Semaphorin 4A Stabilizes Human Regulatory T Cell Phenotype via Plexin B1

scientific article published on 01 February 2019

Semaphorin 4A Stabilizes Human Regulatory T Cell Phenotype via Plexin B1 is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.4049/IMMUNOHORIZONS.1800026
P932PMC publication ID6590919
P698PubMed publication ID31236543

P50authorAmit GoldingQ56250347
Molly HritzoQ93004970
P2093author name stringLuca Tamagnone
Achsah D Keegan
Svetlana P Chapoval
Xiulan Qi
P2860cites workExpression of neuroimmune semaphorins 4A and 4D and their receptors in the lung is enhanced by allergen and vascular endothelial growth factorQ21263141
Antigen-specific regulatory T cells develop via the ICOS-ICOS-ligand pathway and inhibit allergen-induced airway hyperreactivityQ24302386
Neuroimmune semaphorin 4A downregulates the severity of allergic responseQ24601341
Conversion of peripheral CD4+CD25- naive T cells to CD4+CD25+ regulatory T cells by TGF-beta induction of transcription factor Foxp3Q24672849
Foxp3 programs the development and function of CD4+CD25+ regulatory T cellsQ27860714
p53-Dependent and p53-independent activation of autophagy by ARFQ28264892
Neuroimmune semaphorin 4D is necessary for optimal lung allergic inflammationQ28295886
Sema4A induces cell morphological changes through B-type plexin-mediated signalingQ28506174
Nonredundant roles of Sema4A in the immune system: defective T cell priming and Th1/Th2 regulation in Sema4A-deficient miceQ28585413
Epigenetic modification of the FoxP3 TSDR in HAM/TSP decreases the functional suppression of Tregs.Q30371156
Tim-2 regulates T helper type 2 responses and autoimmunityQ33220331
Allergic diseases and asthma: a global public health concern and a call to actionQ33712275
Class IV semaphorin Sema4A enhances T-cell activation and interacts with Tim-2.Q34154039
Ikaros, Aiolos and Helios: transcription regulators and lymphoid malignanciesQ34197736
Defining a functionally distinct subset of human memory CD4+ T cells that are CD25POS and FOXP3NEG.Q34274920
Neuroimmune semaphorin 4A as a drug and drug target for asthmaQ34367862
The role of the transcription factor Foxp3 in the development of regulatory T cellsQ34569892
Expression of Helios, an Ikaros transcription factor family member, differentiates thymic-derived from peripherally induced Foxp3+ T regulatory cellsQ34617154
Stability and function of regulatory T cells is maintained by a neuropilin-1-semaphorin-4a axis.Q34655006
A role for the transcription factor Helios in human CD4(+)CD25(+) regulatory T cellsQ34696683
Smad3 and NFAT cooperate to induce Foxp3 expression through its enhancerQ34729938
CD4 T cells: fates, functions, and faultsQ34813153
Differences in Expression Level of Helios and Neuropilin-1 Do Not Distinguish Thymus-Derived from Extrathymically-Induced CD4+Foxp3+ Regulatory T CellsQ35818676
Helios, and not FoxP3, is the marker of activated Tregs expressing GARP/LAP.Q36299565
The costimulatory role of TIM moleculesQ37474954
The antiproliferative effect of kefir cell-free fraction on HuT-102 malignant T lymphocytesQ37602865
Suppression assays with human T regulatory cells: a technical guide.Q37967572
Asthma phenotypes: the evolution from clinical to molecular approachesQ38007831
Polyclonal Regulatory T Cell Therapy for Control of Inflammation in Kidney Transplants.Q38662974
Hypomethylation of the Treg-Specific Demethylated Region in FOXP3 Is a Hallmark of the Regulatory T-cell Subtype in Adult T-cell LeukemiaQ38810781
Semaphorins 4A and 4D in chronic inflammatory diseases.Q38935490
Regulatory T cells in allergic diseases.Q38946820
A Critical Evaluation of Anti-IL-13 and Anti-IL-4 Strategies in Severe Asthma.Q38956459
Prospects for new and emerging therapeutics in severe asthma: the role of biologicsQ39278773
Clinical-grade regulatory T cells: Comparative analysis of large-scale expansion conditionsQ39331928
Mechanisms of immune regulation in allergic diseases: the role of regulatory T and B cells.Q39402881
Innate and adaptive type 2 immunity in lung allergic inflammation.Q39402938
Activity of deacetylase inhibitor panobinostat (LBH589) in cutaneous T-cell lymphoma models: Defining molecular mechanisms of resistanceQ39744464
Human T-cell lines with well-defined T-cell receptor gene rearrangements as controls for the BIOMED-2 multiplex polymerase chain reaction tubes.Q40195952
Neuropilin-1: a surface marker of regulatory T cellsQ40584286
Regulation of CD3 expression in a protein kinase C isozyme-deficient T-cell lineQ41509951
Cytokines in chronic respiratory diseasesQ42113962
ONC201 selectively induces apoptosis in cutaneous T-cell lymphoma cells via activating pro-apoptotic integrated stress response and inactivating JAK/STAT and NF-κB pathwaysQ42365296
An inhibitory role for Sema4A in antigen-specific allergic asthmaQ45211082
Antigen presentation by the CD4 positive monocyte subsetQ45214423
TGF-beta induces Foxp3 + T-regulatory cells from CD4 + CD25 - precursorsQ45877917
IL-2 is essential for TGF-beta to convert naive CD4+CD25- cells to CD25+Foxp3+ regulatory T cells and for expansion of these cellsQ46040716
Acquisition of anergic and suppressive activities in transforming growth factor-beta-costimulated CD4+CD25- T cellsQ47240613
Plasmacytoid dendritic cells protect from viral bronchiolitis and asthma through semaphorin 4a-mediated T reg expansionQ47561020
Imaging flow cytometry: A method for examining dynamic native FOXO1 localization in human lymphocytesQ47654601
Omalizumab effectively protects against early and late allergic responses in asthma after 4 weeks.Q48329241
Human Semaphorin-4A drives Th2 responses by binding to receptor ILT-4.Q50325168
Histone deacetylase inhibition modulates deoxyribonucleotide pools and enhances the antitumor effects of the ribonucleotide reductase inhibitor 3'-C-methyladenosine in leukaemia cells.Q53268361
Foxp3-dependent and -independent molecules specific for CD25+CD4+ natural regulatory T cells revealed by DNA microarray analysis.Q54597061
Cutaneous T-cell lymphoma: malignant proliferation of T-regulatory cellsQ56903036
CD4+CD25high regulatory cells in human peripheral bloodQ56905059
Plexin signaling hampers integrin-based adhesion, leading to Rho-kinase independent cell rounding, and inhibiting lamellipodia extension and cell motilityQ56914602
A neuronal receptor, neuropilin-1, is essential for the initiation of the primary immune responseQ57218726
T-cell lymphoma cell lines (HUT102 and HUT78) established at the National Cancer Institute: history and importance to understanding the biology, clinical features, and therapy of cutaneous T-cell lymphomas (CTCL) and adult T-cell leukemia-lymphomasQ71529097
Nasal tolerance induces antigen-specific CD4+CD25- regulatory T cells that can transfer their regulatory capacity to naive CD4+ T cellsQ73401157
CD4 and CD8 expression by dendritic cell subtypes in mouse thymus and spleenQ73520530
Neuropilin-1 expression identifies a subset of regulatory T cells in human lymph nodes that is modulated by preoperative chemoradiation therapy in cervical cancerQ79920604
T cell, Ig domain, mucin domain-2 gene-deficient mice reveal a novel mechanism for the regulation of Th2 immune responses and airway inflammationQ80283980
Biologicals for asthma in patients with asthma-COPD overlapQ89425137
P433issue2
P304page(s)71-87
P577publication date2019-02-01
P1476titleSemaphorin 4A Stabilizes Human Regulatory T Cell Phenotype via Plexin B1
P478volume3

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