Decitabine attenuates nociceptive behavior in a murine model of bone cancer pain

scientific article published on 01 March 2019

Decitabine attenuates nociceptive behavior in a murine model of bone cancer pain is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.1097/J.PAIN.0000000000001442
P932PMC publication ID6377317
P698PubMed publication ID30422869

P2093author name stringAnne-Marie Heegaard
Camilla Kristine Appel
Brian Lee Schmidt
Chi Tonglien Viet
Nicole Newell Scheff
P2860cites workBone cancer pain: from mechanism to therapyQ27025262
Activation mechanism of endothelin ETB receptor by endothelin-1Q27727996
A new generation of Ca2+ indicators with greatly improved fluorescence propertiesQ27860793
GSTP1 DNA methylation and expression status is indicative of 5-aza-2'-deoxycytidine efficacy in human prostate cancer cellsQ28477278
Decitabine rescues cisplatin resistance in head and neck squamous cell carcinomaQ28544907
Endothelin-B receptor activation triggers an endogenous analgesic cascade at sites of peripheral injuryQ28564446
CpG island methylator phenotype underlies sporadic microsatellite instability and is tightly associated with BRAF mutation in colorectal cancerQ29614277
Ethical guidelines for investigations of experimental pain in conscious animalsQ29617510
Dissociation between the relief of skeletal pain behaviors and skin hypersensitivity in a model of bone cancer painQ30831131
Methylnaltrexone for opioid-induced constipation in advanced illnessQ33439945
Hypermethylation of EDNRB promoter contributes to the risk of colorectal cancerQ33645099
Peripheral endothelin B receptor agonist-induced antinociception involves endogenous opioids in miceQ33814735
Evidence for the endothelin system as an emerging therapeutic target for the treatment of chronic painQ34140692
Use of opioid analgesics in the treatment of cancer pain: evidence-based recommendations from the EAPC.Q34251507
Attenuation of activity in an endogenous analgesia circuit by ongoing pain in the ratQ34267113
Malignant bone pain: pathophysiology and treatmentQ34418896
Peripheral mechanisms of opioid analgesiaQ34926296
Demethylating drugs as novel analgesics for cancer pain.Q34959705
Endothelin-1-induced ET(A) receptor-mediated nociception, hyperalgesia and oedema in the mouse hind-paw: modulation by simultaneous ET(B) receptor activationQ35041995
Evaluation of mammary gland development and function in mouse modelsQ35379314
Precision and performance characteristics of bisulfite conversion and real-time PCR (MethyLight) for quantitative DNA methylation analysisQ35790157
DNA Methylation Modulates Nociceptive Sensitization after IncisionQ35831786
Re-expression of the methylated EDNRB gene in oral squamous cell carcinoma attenuates cancer-induced painQ36031497
Modulation by decitabine of gene expression and growth of osteosarcoma U2OS cells in vitro and in xenografts: identification of apoptotic genes as targets for demethylationQ36082658
Endogenous opioids inhibit early-stage pancreatic pain in a mouse model of pancreatic cancerQ36178615
Epigenetic regulation by decitabine of melanoma differentiation in vitro and in vivoQ36266756
Contribution of endoplasmic reticulum Ca2+ regulatory mechanisms to the inflammation-induced increase in the evoked Ca2+ transient in rat cutaneous dorsal root ganglion neuronsQ36900946
Knockout of endothelin type B receptor signaling attenuates bleomycin-induced skin sclerosis in miceQ36923228
Spinal cord mechanisms of painQ37140262
Effect of peripheral endothelin-1 concentration on carcinoma-induced pain in miceQ37407420
Epigenetic regulation of HGF/Met receptor axis is critical for the outgrowth of bone metastasis from breast carcinomaQ37745101
European Palliative Care Research collaborative pain guidelines. Central side-effects management: what is the evidence to support best practice in the management of sedation, cognitive impairment and myoclonus?Q37792645
Early progress in epigenetic regulation of endothelin pathway genesQ37973381
Bone cancer pain: causes, consequences, and therapeutic opportunitiesQ38126710
Pain and nociception: mechanisms of cancer-induced bone painQ38209631
Cancer induced bone painQ38336942
Endothelin-1 production and decreased endothelin B receptor expression in advanced prostate cancerQ38361625
Importance of dose-schedule of 5-aza-2'-deoxycytidine for epigenetic therapy of cancerQ38529787
Bone pain: current and future treatments.Q38759480
Study of breakthrough cancer pain in an animal model induced by endothelin-1.Q38797886
High-incidence spontaneous tumors in JF1/Ms mice: relevance of hypomorphic germline mutation and subsequent promoter methylation of EdnrbQ39066757
Decitabine, independent of apoptosis, exerts its cytotoxic effects on cell growth in melanoma cellsQ39456914
P2X7 receptor-deficient mice are susceptible to bone cancer pain.Q39544211
DNA methyltransferase deficiency modifies cancer susceptibility in mice lacking DNA mismatch repairQ39674490
Endothelin-1 enhances proliferation of lung cancer cells by increasing intracellular free Ca2+.Q40009811
Comparison of biological effects of non-nucleoside DNA methylation inhibitors versus 5-aza-2'-deoxycytidine.Q40361515
Coordinate regulation of microenvironmental stimuli and role of methylation in bone metastasis from breast carcinomaQ40415482
The control of pain in peripheral tissue by opioids.Q40531445
New bone formation in an osteoblastic tumor model is increased by endothelin-1 overexpression and decreased by endothelin A receptor blockadeQ40957581
Identification of endothelin–1 in the pathophysiology of metastatic adenocarcinoma of the prostateQ41304383
Pain-induced analgesia mediated by mesolimbic reward circuitsQ41683720
The role of DNA damage and repair in decitabine-mediated apoptosis in multiple myelomaQ42459032
The endothelin receptor B (EDNRB) promoter displays heterogeneous, site specific methylation patterns in normal and tumor cellsQ43579789
Influence of sex differences on the progression of cancer-induced bone painQ44282139
Opioid receptors and endogenous opioids in diverse human and animal cancersQ44342157
Local peripheral effects of mu-opioid receptor agonists in neuropathic pain in ratsQ44345132
Microenvironmental stimuli affect Endothelin-1 signaling responsible for invasiveness and osteomimicry of bone metastasis from breast cancerQ44539462
Activation of p53/p21Waf1/Cip1 pathway by 5-aza-2'-deoxycytidine inhibits cell proliferation, induces pro-apoptotic genes and mitogen-activated protein kinases in human prostate cancer cells.Q45309425
MethyLightQ46394365
Acute stress contributes to individual differences in pain and pain-related brain activity in healthy and chronic pain patients.Q46757999
Spontaneous pain-like behaviors are more sensitive to morphine and buprenorphine than mechanically evoked behaviors in a rat model of acute postoperative pain.Q46796521
Incidence of bone metastases in patients with solid tumors: analysis of oncology electronic medical records in the United StatesQ47202399
Endothelin and the tumorigenic component of bone cancer painQ47320031
Expression of endothelin-1, endothelin-A, and endothelin-B receptor in human breast cancer and correlation with long-term follow-upQ47594375
Tumor necrosis factor alpha secreted from oral squamous cell carcinoma contributes to cancer pain and associated inflammationQ48014095
Mu-opioid antagonists for opioid-induced bowel dysfunction in people with cancer and people receiving palliative careQ57689172
Production of dissociated sensory neuron cultures and considerations for their use in studying neuronal function and plasticityQ60681167
Neuropeptide Y is Up-regulated and Induces Antinociception in Cancer-induced Bone PainQ60745189
Analgesic effect of intraarticular morphine after arthroscopic knee surgeryQ68253539
Endothelin-1 participation in overt and inflammatory painQ69084409
Endothelins potentiate formalin-induced nociception and paw edema in miceQ73640341
Local injection of a selective endothelin-B receptor agonist inhibits endothelin-1-induced pain-like behavior and excitation of nociceptors in a naloxone-sensitive mannerQ74661539
Endogenous beta-endorphin induces thermal analgesia at the initial stages of a murine osteosarcomaQ80163328
A role for endothelin in neuropathic pain after chronic constriction injury of the sciatic nerveQ81511338
Endothelin: Ominous Player in Breast CancerQ94365440
P4510describes a project that usesImageJQ1659584
P433issue3
P921main subjectbone cancerQ18554919
cancer painQ3712728
murine modelQ122890741
P304page(s)619-631
P577publication date2019-03-01
P1433published inPainQ2317902
P1476titleDecitabine attenuates nociceptive behavior in a murine model of bone cancer pain
P478volume160