Inflammation induces endothelial-to-mesenchymal transition and promotes vascular calcification through downregulation of BMPR2

scientific article published on 16 January 2019

Inflammation induces endothelial-to-mesenchymal transition and promotes vascular calcification through downregulation of BMPR2 is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.1002/PATH.5193
P932PMC publication ID6590480
P698PubMed publication ID30430573

P50authorMarie-José GoumansQ59390020
Hans van DamQ64513644
Peter Ten DijkeQ87987980
Gonzalo Sanchez-DuffhuesQ88807823
P2093author name stringMargreet R de Vries
Amaya García de Vinuesa
Jan H Lindeman
Vera van de Pol
Marlieke E Geerts
Stef Gt Janson
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ALK2 R206H mutation linked to fibrodysplasia ossificans progressiva confers constitutive activity to the BMP type I receptor and sensitizes mesenchymal cells to BMP-induced osteoblast differentiation and bone formationQ28265302
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Inflammation-induced endothelial-to-mesenchymal transition: a novel mechanism of intestinal fibrosisQ35474247
Long-Term Expansion in Platelet Lysate Increases Growth of Peripheral Blood-Derived Endothelial-Colony Forming Cells and Their Growth Factor-Induced Sprouting CapacityQ35664202
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Selective enhancement of endothelial BMPR-II with BMP9 reverses pulmonary arterial hypertension.Q35832692
Endothelial-Mesenchymal Transition in Vascular Calcification of Ins2Akita/+ Mice.Q36218686
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Microtubule stabilization by bone morphogenetic protein receptor-mediated scaffolding of c-Jun N-terminal kinase promotes dendrite formationQ39736479
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DNA damage in transcribed genes induces apoptosis via the JNK pathway and the JNK-phosphatase MKP-1.Q40393322
Constitutive JNK activation in NIH 3T3 fibroblasts induces a partially transformed phenotypeQ40728305
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Bone morphogenetic protein 9 (BMP9) and BMP10 enhance tumor necrosis factor-α-induced monocyte recruitment to the vascular endothelium mainly via activin receptor-like kinase 2.Q41484602
SLUG is expressed in endothelial cells lacking primary cilia to promote cellular calcificationQ41509428
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Anti-human activin receptor-like kinase 1 (ALK1) antibody attenuates bone morphogenetic protein 9 (BMP9)-induced ALK1 signaling and interferes with endothelial cell sproutingQ41964822
Cloned spindle and epithelioid cells from murine Kaposi's sarcoma-like tumors are of endothelial originQ42810465
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Role for Runt-related Transcription Factor 2 in Proliferative and Calcified Vascular Lesions in Pulmonary Arterial Hypertension.Q46277870
Endothelial-to-mesenchymal transition in cardiovascular diseases: Developmental signaling pathways gone awryQ48096975
Integrin-YAP/TAZ-JNK cascade mediates atheroprotective effect of unidirectional shear flow.Q51281265
Impaired fracture healing in the absence of TNF-alpha signaling: the role of TNF-alpha in endochondral cartilage resorption.Q52100443
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Accelerated atherosclerosis and calcification in vein grafts: a study in APOE*3 Leiden transgenic mice.Q55036145
Endothelial-to-mesenchymal transition in pulmonary hypertension.Q55068646
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The natural history of aortic atherosclerosis: a systematic histopathological evaluation of the peri-renal regionQ82325127
P4510describes a project that usesImageJQ1659584
P433issue3
P921main subjectvascular calcificationQ54911504
P304page(s)333-346
P577publication date2019-01-16
P1433published inJournal of PathologyQ400296
P1476titleInflammation induces endothelial-to-mesenchymal transition and promotes vascular calcification through downregulation of BMPR2
P478volume247

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cites work (P2860)
Q91588126Endothelial Colony Forming Cells as an Autologous Model to Study Endothelial Dysfunction in Patients with a Bicuspid Aortic Valve
Q95338257Growth differentiation factor 15 in adverse cardiac remodelling: from biomarker to causal player
Q90334233Interplay between BMPs and Reactive Oxygen Species in Cell Signaling and Pathology
Q91730362Lethal giant larvae 1 inhibits smooth muscle calcification via high mobility group box 1
Q90631576Research Models for Studying Vascular Calcification
Q94479612TGF-beta and TNF-alpha cooperatively induce mesenchymal transition of lymphatic endothelial cells via activation of Activin signals
Q94564513TGF-β-Induced Endothelial to Mesenchymal Transition in Disease and Tissue Engineering

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