NFATc3 controls tumour growth by regulating proliferation and migration of human astroglioma cells

scientific article published on 27 June 2019

NFATc3 controls tumour growth by regulating proliferation and migration of human astroglioma cells is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.1038/S41598-019-45731-W
P932PMC publication ID6597574
P698PubMed publication ID31249342

P50authorSonsoles HortelanoQ51520011
Pilar Sánchez-GómezQ58788702
Juan Miguel RedondoQ58840487
Eva CanoQ60321241
P2093author name stringAurelio Hernández-Laín
Katia Urso
Javier Cotrina
Andrés Fernández
Belén de Andrés
Patricia Velasco
P2860cites workExpression of NFAT-family proteins in normal human T cellsQ24646521
Preclinical Test of Dacomitinib, an Irreversible EGFR Inhibitor, Confirms Its Effectiveness for GlioblastomaQ27853163
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Secreted frizzle-related protein 2 stimulates angiogenesis via a calcineurin/NFAT signaling pathwayQ28505775
Activation of peroxisome proliferator-activated receptor gamma inhibits endothelin-1-induced cardiac hypertrophy via the calcineurin/NFAT signaling pathwayQ28580167
Gliomas induce and exploit microglial MT1-MMP expression for tumor expansionQ30489174
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Tight control of exogenous SERCA expression is required to obtain acceleration of calcium transients with minimal cytotoxic effects in cardiac myocytesQ32069272
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A preclinical orthotopic model for glioblastoma recapitulates key features of human tumors and demonstrates sensitivity to a combination of MEK and PI3K pathway inhibitorsQ34818301
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NFAT1 promotes intratumoral neutrophil infiltration by regulating IL8 expression in breast cancerQ35630191
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Transcriptional regulation of the human interleukin-6 gene promoter in human T-cell leukemia virus type I-infected T-cell lines: evidence for the involvement of NF-kappa B.Q38302916
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Regulator of calcineurin 1 mediates pathological vascular wall remodelingQ38583217
Cytokine Signaling in Tumor ProgressionQ38598868
NFATc1 activation promotes the invasion of U251 human glioblastoma multiforme cells through COX-2.Q38903683
CX3CR1/CX3CL1 axis negatively controls glioma cell invasion and is modulated by transforming growth factor-β1.Q39698815
Calcium/calcineurin signaling in primary cortical astrocyte cultures: Rcan1-4 and cyclooxygenase-2 as NFAT target genes.Q40009971
CXCR3 and its binding chemokines in myeloma cells: expression of isoforms and potential relationships with myeloma cell proliferation and survivalQ40212749
NFAT induces breast cancer cell invasion by promoting the induction of cyclooxygenase-2.Q40310709
Cyclosporine a induces growth arrest or programmed cell death of human glioma cells.Q40387310
Platelet-activating factor-induced chemokine gene expression requires NF-kappaB activation and Ca2+/calcineurin signaling pathways. Inhibition by receptor phosphorylation and beta-arrestin recruitmentQ40525980
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MCP-1 expression in CNS-1 astrocytoma cells: implications for macrophage infiltration into tumors in vivoQ40738678
Regulator of calcineurin 1 (Rcan1) has a protective role in brain ischemia/reperfusion injuryQ42547344
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NFAT4 is expressed in primary astrocytes and activated by glutamateQ44387885
Oxidative and calcium stress regulate DSCR1 (Adapt78/MCIP1) protein.Q44555300
Renaming the DSCR1/Adapt78 gene family as RCAN: regulators of calcineurin.Q44832032
Depolarization of neural cells induces transcription of the Down syndrome critical region 1 isoform 4 via a calcineurin/nuclear factor of activated T cells-dependent pathwayQ46564469
Targeted deletion of the calcineurin inhibitor DSCR1 suppresses tumor growthQ46613131
Nuclear factor of activated T cells (NFAT) as a new component of the signal transduction pathway in glioma cells.Q47903767
The invasion promoting effect of microglia on glioblastoma cells is inhibited by cyclosporin A.Q48369087
GlioVis data portal for visualization and analysis of brain tumor expression datasetsQ48379249
Analysis of interleukin (IL)-8 expression in human astrocytomas: associations with IL-6, cyclooxygenase-2, vascular endothelial growth factor, and microvessel morphometryQ48682386
NFATc3 regulates the transcription of genes involved in T-cell activation and angiogenesis.Q53242935
Regulation of interleukin-8 expression by reduced oxygen pressure in human glioblastomaQ58323583
Calcium Signaling in Brain Cancers: Roles and Therapeutic TargetingQ64243523
Inhibition of T cell signaling by immunophilin-ligand complexes correlates with loss of calcineurin phosphatase activityQ67534468
The effects of cyclosporin A and FK506 on proliferation and IL-8 production of cultured human keratinocytesQ70818929
NF-ATp, a T lymphocyte DNA-binding protein that is a target for calcineurin and immunosuppressive drugsQ72069311
Quantitative determination of lentiviral vector particle numbers by real-time PCRQ74551285
P4510describes a project that usesImageJQ1659584
P433issue1
P921main subjectcell migrationQ189092
P304page(s)9361
P577publication date2019-06-27
P1433published inScientific ReportsQ2261792
P1476titleNFATc3 controls tumour growth by regulating proliferation and migration of human astroglioma cells
P478volume9

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Q89659079The Role of TRPC1 in Modulating Cancer Progressioncites workP2860

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