GutSelf: Interindividual Variability in the Processing of Dietary Compounds by the Human Gastrointestinal Tract

scientific article published on 01 October 2019

GutSelf: Interindividual Variability in the Processing of Dietary Compounds by the Human Gastrointestinal Tract is …
instance of (P31):
review articleQ7318358
scholarly articleQ13442814

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P356DOI10.1002/MNFR.201900677
P932PMC publication ID6900003
P698PubMed publication ID31483113

P50authorGuy VergèresQ91983129
Francesca DanesiQ42368338
P2093author name stringAlexandra Schmid
Didier Dupont
Danit R Shahar
Alessandra Bordoni
Barbara Walther
Lidia Tomás-Cobos
Amélie Deglaire
Aida Sainz Fernandez
Roberta Re
Doreen Gille
Aaron M Lett
Ana Echaniz
Juan Antonio Nieto
P2860cites workMultiple functions of microsomal triglyceride transfer proteinQ21245057
The fatty acid translocase gene CD36 and lingual lipase influence oral sensitivity to fat in obese subjectsQ22337004
A G protein-coupled receptor responsive to bile acidsQ24338558
Linking long-term dietary patterns with gut microbial enterotypesQ24609914
The SLC6A14 gene shows evidence of association with obesityQ24654114
The reduced folate carrier (SLC19A1) c.80G>A polymorphism is associated with red cell folate concentrations among womenQ24657376
The Functions of Metallothionein and ZIP and ZnT Transporters: An Overview and PerspectiveQ26766916
Lactose Intolerance in Adults: Biological Mechanism and Dietary ManagementQ26782227
From 'lactose intolerance' to 'lactose nutrition'Q26827397
Human genetic variation influences vitamin C homeostasis by altering vitamin C transport and antioxidant enzyme functionQ27024648
Low serum amylase and obesity, diabetes and metabolic syndrome: A novel interpretationQ28066021
Heritability of plasma noncholesterol sterols and relationship to DNA sequence polymorphism in ABCG5 and ABCG8Q28207077
SLC26A3 mutations in congenital chloride diarrheaQ28215471
Cloning and gene defects in microsomal triglyceride transfer protein associated with abetalipoproteinaemiaQ28262033
Procolipase gene: no association with early-onset obesity or fat intakeQ28269501
Mutations in SLC6A19, encoding B0AT1, cause Hartnup disorderQ28275108
Plasma levels of lathosterol and phytosterols in relation to age, sex, anthropometric parameters, plasma lipids, and apolipoprotein E phenotype, in 160 Dutch familiesQ67934513
Serum plant sterols and cholesterol precursors reflect cholesterol absorption and synthesis in volunteers of a randomly selected male populationQ68689666
The secretin-pancreozymin test in the diagnosis of pancreatic insufficiencyQ69932540
Bile acids and pancreatic enzymes during absorption in the newbornQ70437036
Fat preference and adherence to a reduced-fat dietQ70574084
Transport and metabolism of water-soluble vitamins in intestine and kidneyQ71353276
Dietary fat modulates gastric lipase activity in healthy humansQ71838565
Protein digestibility of the same protein preparations by human and rat assays and by in vitro enzymic digestion methodsQ72126714
Postprandial modulation of dietary and whole-body nitrogen utilization by carbohydrates in humansQ73019090
Differential expression of ACAT1 and ACAT2 among cells within liver, intestine, kidney, and adrenal of nonhuman primatesQ73275731
Variability of the masticatory process during chewing of elastic model foodsQ73387208
Fat perception is related to PROP taster statusQ73401797
Will recommended changes in fat and fibre intake affect cholesterol absorption and sterol excretion? An ileostomy studyQ73616966
The influence of the albumin fraction on the bioavailability and postprandial utilization of pea protein given selectively to humansQ73953847
Assessment of net postprandial protein utilization of 15N-labelled milk nitrogen in human subjectsQ78091423
The poor digestibility of rapeseed protein is balanced by its very high metabolic utilization in humansQ79802985
Reduction of cholesterol absorption by dietary plant sterols and stanols in mice is independent of the Abcg5/8 transporterQ79954670
Postprandial metabolic utilization of wheat protein in humansQ81247024
Functional analysis of promoter variants in the microsomal triglyceride transfer protein (MTTP) geneQ81247400
Marked differences in gustatory and gastrointestinal sensitivity to oleic acid between lean and obese menQ83395424
Postmastication digestion factors influence glycemic variability in humansQ84538807
G protein-coupled receptors in human fat taste perceptionQ84831179
Characterization of duodenal expression and localization of fatty acid-sensing receptors in humans: relationships with body mass indexQ85640681
Fat-soluble vitamin intestinal absorption: absorption sites in the intestine and interactions for absorptionQ86096179
Increased number of chews during a fixed-amount meal suppresses postprandial appetite and modulates glycemic response in older malesQ87941805
Impact of sugar on the body, brain, and behaviorQ88717681
Recent insights into the role of ChREBP in intestinal fructose absorption and metabolismQ58795278
Postprandial Evolution in Composition and Characteristics of Human Duodenal Fluids in Different Nutritional StatesQ59285656
Variability of human saliva composition: Possible relationships with fat perception and likingQ60453783
Hereditary hemochromatosis type 1 phenotype modifiers in Italian patients. The controversial role of variants in HAMP, BMP2, FTL and SLC40A1 genesQ61899301
Long-term treatment of hypercholesterolaemia with a new palatable formulation of guar gumQ67263959
Polymorphisms in the amino acid transporter solute carrier family 6 (neurotransmitter transporter) member 14 gene contribute to polygenic obesity in French CaucasiansQ28279030
Compensatory phospholipid digestion is required for cholesterol absorption in pancreatic phospholipase A(2)-deficient miceQ28511201
A novel multiprotein complex is required to generate the prechylomicron transport vesicle from intestinal ERQ28567584
Genome-wide meta-analysis of observational studies shows common genetic variants associated with macronutrient intakeQ30412686
Vitamin D receptor Fok1 polymorphisms affect calcium absorption, kinetics, and bone mineralization rates during puberty.Q31171610
Genetic variation and lactose intolerance: detection methods and clinical implicationsQ33431965
Personalized Nutrition by Prediction of Glycemic Responses.Q33445995
Dietary fiber and prebiotics and the gastrointestinal microbiotaQ33562095
Vitamin Pharmacogenomics: New Insight into Individual Differences in Diseases and Drug ResponsesQ33631610
Circadian rhythms and metabolic syndrome: from experimental genetics to human disease.Q33722806
Intestinal absorption of water-soluble vitamins in health and diseaseQ33725184
Enhanced passive Ca2+ reabsorption and reduced Mg2+ channel abundance explains thiazide-induced hypocalciuria and hypomagnesemiaQ33775321
Overexpression of Transcobalamin 1 is an Independent Negative Prognosticator in Rectal Cancers Receiving Concurrent ChemoradiotherapyQ33820817
Interindividual variability and intra-individual reproducibility of glycemic index values for commercial white breadQ34003165
Obesity, starch digestion and amylase: association between copy number variants at human salivary (AMY1) and pancreatic (AMY2) amylase genesQ34043497
Bile acid metabolites in serum: intraindividual variation and associations with coronary heart disease, metabolic syndrome and diabetes mellitusQ34081372
ABCG5/G8 polymorphisms and markers of cholesterol metabolism: systematic review and meta-analysisQ34116372
Genetic variation in GPBAR1 predisposes to quantitative changes in colonic transit and bile acid excretionQ34131127
Prebiotic effects: metabolic and health benefitsQ34141652
Effects of plant sterols and stanols on intestinal cholesterol metabolism: suggested mechanisms from past to presentQ34276947
Molecular structure of tight junctions and their role in epithelial transport.Q34302113
Genetically heterogeneous selective intestinal malabsorption of vitamin B12: founder effects, consanguinity, and high clinical awareness explain aggregations in Scandinavia and the Middle EastQ34306368
Expression cloning and characterization of a novel adipocyte long chain fatty acid transport proteinQ34325172
Deficiency of acyl CoA:cholesterol acyltransferase 2 prevents atherosclerosis in apolipoprotein E-deficient miceQ34330253
Exome-wide association study identifies a TM6SF2 variant that confers susceptibility to nonalcoholic fatty liver diseaseQ34404491
Biosynthesis of triacylglycerolsQ34409520
Vitamin D bioavailability: state of the art.Q34423940
Effects of antinutritional factors on protein digestibility and amino acid availability in foods.Q34431969
Acyl-CoA: cholesterol acyltransferase-2 gene polymorphisms and their association with plasma lipids and coronary artery disease risks.Q34455584
Bile acid synthesis in humans has a rapid diurnal variation that is asynchronous with cholesterol synthesisQ34467201
Digestibility of cooked and raw egg protein in humans as assessed by stable isotope techniquesQ34475183
Multiple rare variants in NPC1L1 associated with reduced sterol absorption and plasma low-density lipoprotein levelsQ34478587
Bile acid secretion in cystic fibrosis: evidence for a defect unrelated to fat malabsorptionQ34530665
New insights into cystinuria: 40 new mutations, genotype-phenotype correlation, and digenic inheritance causing partial phenotypeQ34553967
Oral detection of short-, medium-, and long-chain free fatty acids in humansQ37091079
Common variants in the CD36 gene are associated with oral fat perception, fat preferences, and obesity in African AmericansQ37095831
Brief oral stimulation, but especially oral fat exposure, elevates serum triglycerides in humansQ37100295
Physiology of Intestinal Absorption and SecretionQ37115961
Vitamin D and agingQ37195168
Vitamin C transporter gene (SLC23A1 and SLC23A2) polymorphisms, plasma vitamin C levels, and gastric cancer risk in the EPIC cohortQ37300010
Associations between single nucleotide polymorphisms in folate uptake and metabolizing genes with blood folate, homocysteine, and DNA uracil concentrationsQ37309187
Acyl chain length, saturation, and hydrophobicity modulate the efficiency of dietary fatty acid absorption in adult humansQ37342060
A novel association between a SNP in CYBRD1 and serum ferritin levels in a cohort study of HFE hereditary haemochromatosisQ37399509
Vitamin D gene pathway polymorphisms and risk of colorectal, breast, and prostate cancerQ37463085
Diet and Gut Microbial Function in Metabolic and Cardiovascular Disease RiskQ37595816
Fat and fatty acid terminology, methods of analysis and fat digestion and metabolism: a background review paperQ37596829
The mechanism of the formation and secretion of chylomicronsQ37759662
Involvement of CD36 and intestinal alkaline phosphatases in fatty acid transport in enterocytes, and the response to a high-fat dietQ37822516
Oral fatty acid signaling and intestinal lipid processing: support and suppositionQ37842838
Effects of dietary fat on appetite and energy intake in health and obesity--oral and gastrointestinal sensory contributionsQ37877303
Genetic variations involved in interindividual variability in carotenoid status.Q37940438
The impact of nutrition on the human microbiomeQ38031933
Copy number polymorphism of the salivary amylase gene: implications in human nutrition research.Q38042330
Is there a dose-response relation of dietary glycemic load to risk of type 2 diabetes? Meta-analysis of prospective cohort studiesQ38077878
Mammalian iron transporters: families SLC11 and SLC40.Q38090772
Fat taste in humans: sources of within- and between-subject variabilityQ38107747
Bioavailability of vitamin E in humans: an updateQ38111475
Specificity of infant digestive conditions: some clues for developing relevant in vitro models.Q38192074
Intestinal lipid absorption and lipoprotein formationQ38206075
Insights from human congenital disorders of intestinal lipid metabolismQ38267212
Recent advances in fatty acid perception and geneticsQ38483555
Transporters for the Intestinal Absorption of Cholesterol, Vitamin E, and Vitamin K.Q38768787
Genetic and environmental modifiers of Wilson diseaseQ38825242
Functional characterization of two single nucleotide polymorphisms of acyl-coenzyme A:cholesterol acyltransferase 2.Q38881748
TM6SF2 rs58542926 impacts lipid processing in liver and small intestine.Q39062036
Host-related factors explaining interindividual variability of carotenoid bioavailability and tissue concentrations in humansQ39094660
Expression and function of the bile acid receptor GpBAR1 (TGR5) in the murine enteric nervous system.Q39726655
Gastrointestinal digestion and absorption of lipidQ39826401
Degree of particle size breakdown during mastication may be a possible cause of interindividual glycemic variability.Q39865732
NPC1L1 (Niemann-Pick C1-like 1) mediates sterol-specific unidirectional transport of non-esterified cholesterol in McArdle-RH7777 hepatoma cellsQ40128303
Intestinal synthesis, secretion, and transport of lipoproteinsQ40207202
Clinical relevance of intestinal peptide uptakeQ40244905
Intestinal fat digestion, absorption, and transport. A reviewQ40282858
ATP-binding cassette transporter G8 M429V polymorphism as a novel genetic marker of higher cholesterol absorption in hypercholesterolaemic Japanese subjectsQ40432217
Detection of a promoter polymorphism in the gene of intestinal fatty acid binding protein (I-FABP).Q40722963
Synthesis and secretion of hepatic apolipoprotein B-containing lipoproteins.Q40750994
Localization of the lipid receptors CD36 and CLA-1/SR-BI in the human gastrointestinal tract: towards the identification of receptors mediating the intestinal absorption of dietary lipidsQ40780084
The basal secretion of pepsin by the human stomachQ40981169
THE ROLE OF PEPSIN, PEPTIC INHIBITORY SUBSTANCES, AND HYDROCHLORIC ACID IN NORMAL SUBJECTS AND IN THE PRODUCTION OF PEPTIC ULCERS.Q40997260
Analysis and update of the human solute carrier (SLC) gene superfamilyQ41857194
The apolipoprotein A5 (APOA5) gene predisposes Caucasian children to elevated triglycerides and vitamin E (Four Provinces Study).Q42945169
Vitamin C transporter gene polymorphisms, dietary vitamin C and serum ascorbic acidQ43001411
Oral sensitivity to fatty acids, food consumption and BMI in human subjectsQ43144935
In-vitro characterization of the six clustered variants of NPC1L1 observed in cholesterol low absorbersQ43262889
Ileal digestibility of dietary protein in the growing pig and adult humanQ43286318
Recent fat intake modulates fat taste sensitivity in lean and overweight subjectsQ43464262
Sequential release of milk protein-derived bioactive peptides in the jejunum in healthy humans.Q43762610
Minced beef is more rapidly digested and absorbed than beef steak, resulting in greater postprandial protein retention in older men.Q43796105
Variants of the microsomal triglyceride transfer protein gene are associated with plasma cholesterol levels and body mass indexQ43855756
The bioavailability and postprandial utilisation of sweet lupin (Lupinus albus)-flour protein is similar to that of purified soyabean protein in human subjects: a study using intrinsically 15N-labelled proteinsQ44027563
Resistance to diet-induced hypercholesterolemia and gallstone formation in ACAT2-deficient miceQ44094368
A gut microbiota-targeted dietary intervention for amelioration of chronic inflammation underlying metabolic syndromeQ34629179
Genetic regulation of serum phytosterol levels and risk of coronary artery diseaseQ34660068
Phytosterols in human nutritionQ34676113
Amino acid transport across mammalian intestinal and renal epitheliaQ34736025
Enterocyte fatty acid-binding proteins (FABPs): different functions of liver and intestinal FABPs in the intestineQ35071134
Gut microbiota signatures predict host and microbiota responses to dietary interventions in obese individualsQ35113086
A perspective on the complexity of dietary fiber structures and their potential effect on the gut microbiotaQ35218153
INTESTINAL ABSORPTION OF FATS.Q35469270
New Insights into the Regulation of Chylomicron ProductionQ35631859
Understanding the gastrointestinal tract of the elderly to develop dietary solutions that prevent malnutritionQ35668855
MTTP-297H polymorphism reduced serum cholesterol but increased risk of non-alcoholic fatty liver disease-a cross-sectional study.Q35803568
Fat in the intestine as a regulator of appetite--role of CCK.Q35994542
Recent advances in small bowel diseases: Part II.Q36093336
In vivo determination of amino acid bioavailability in humans and model animals.Q36185582
Intestine-specific MTP and global ACAT2 deficiency lowers acute cholesterol absorption with chylomicrons and HDLsQ36196789
β-Carotene 15,15'-monooxygenase 1 single nucleotide polymorphisms in relation to plasma carotenoid and retinol concentrations in women of European descentQ36398341
Mechanisms involved in the intestinal absorption of dietary vitamin A and provitamin A carotenoidsQ36475339
The G-protein-coupled receptor GPR40 directly mediates long-chain fatty acid-induced secretion of cholecystokininQ36477035
Microsomal triglyceride transfer protein gene -493G/T polymorphism and its association with serum lipid levels in Bama Zhuang long-living families in ChinaQ36560992
Plasma concentrations of plant sterols: physiology and relationship with coronary heart disease.Q36604244
Regulation of intestinal cholesterol absorptionQ36604358
Role of the gut in lipid homeostasisQ36660888
Genetic Variation in Human Vitamin C Transporter Genes in Common Complex Diseases.Q36670980
Human pancreatic digestive enzymesQ36700204
Effect of SNPs on iron metabolismQ36776654
CYP24A1 and CYP27B1 polymorphisms modulate vitamin D metabolism in colon cancer cells.Q36778121
Digestibilities of energy, protein, fat and nonstarch polysaccharides in a low fiber diet and diets containing coarse or fine whole meal rye are comparable in rats and humansQ36799222
Heritable variation in food preferences and their contribution to obesityQ36824623
Vitamin K nutrition, metabolism, and requirements: current concepts and future researchQ36828726
Human nutrition and genetic variationQ36830072
Functionality of fatty acid chemoreception: a potential factor in the development of obesity?Q36994085
Guar gum and similar soluble fibers in the regulation of cholesterol metabolism: current understandings and future research prioritiesQ37019897
Association of ferroportin Q248H polymorphism with elevated levels of serum ferritin in African Americans in the Hemochromatosis and Iron Overload Screening (HEIRS) StudyQ37055398
Effect of genotype on micronutrient absorption and metabolism: a review of iron, copper, iodine and selenium, and folates.Q37063254
Protection against diet-induced obesity and obesity- related insulin resistance in Group 1B PLA2-deficient miceQ44176917
Effects of gender, age, and body mass index on gastrointestinal transit timesQ44456437
The effect of addition of linoleic acid on food intake regulation in linoleic acid tasters and linoleic acid non-tastersQ44502442
Colonic absorption of bacterially synthesized vitamin K2 in the ratQ44615755
The postprandial chylomicron triacylglycerol response to dietary fat in healthy male adults is significantly explained by a combination of single nucleotide polymorphisms in genes involved in triacylglycerol metabolismQ44668831
Lack of the intestinal Muc1 mucin impairs cholesterol uptake and absorption but not fatty acid uptake in Muc1-/- miceQ44838177
Cholesterol absorption is mainly regulated by the jejunal and ileal ATP-binding cassette sterol efflux transporters Abcg5 and Abcg8 in miceQ44854850
Effects of intraduodenal fatty acids on appetite, antropyloroduodenal motility, and plasma CCK and GLP-1 in humans vary with their chain lengthQ44912774
Polymorphisms in the ABCG5 and ABCG8 genes associate with cholesterol absorption and insulin sensitivityQ44919511
Common sequence variations in ABCG8 are related to plant sterol metabolism in healthy volunteersQ45134243
Rapid alternative absorption of dietary long-chain fatty acids with upregulation of intestinal glycosylated CD36 in liver cirrhosisQ45668706
Polyunsaturated fatty acids down-regulate in vitro expression of the key intestinal cholesterol absorption protein NPC1L1: no effect of monounsaturated nor saturated fatty acids.Q46011608
Adaptive regulation of intestinal folate uptake: effect of dietary folate deficiency.Q46036330
Changes in plasma triacylglycerol concentrations after sequential lunch and dinner in healthy subjectsQ46415489
Trimethylamine-N-oxide (TMAO) response to animal source foods varies among healthy young men and is influenced by their gut microbiota composition: A randomized controlled trial.Q46523205
Biochemical basis for retinol deficiency induced by the I41N and G75D mutations in human plasma retinol-binding protein.Q46698714
Compensatory increase in hepatic lipogenesis in mice with conditional intestine-specific Mttp deficiency.Q46851248
Baseline plasma plant sterol concentrations do not predict changes in serum lipids, C-reactive protein (CRP) and plasma plant sterols following intake of a plant sterol-enriched foodQ46855115
Body weight and prior depletion affect plasma ascorbate levels attained on identical vitamin C intake: a controlled-diet studyQ47250434
The association of body weight, dietary intake, and energy expenditure with dietary restraint and disinhibitionQ47358655
Clinical & Vitamin Response to a Short-Term Multi-Micronutrient Intervention in Brazilian Children & Teens: From Population Data to Inter-Individual Responses.Q47556671
Towards utilization of the human genome and microbiome for personalized nutritionQ47582283
PepT1 oligopeptide transporter (SLC15A1) gene polymorphism in inflammatory bowel diseaseQ47744754
Factors influencing the absorption of vitamin D in GIT: an overview.Q48100475
Relative contribution of α-carotene to postprandial vitamin A concentrations in healthy humans after carrot consumption.Q48130604
A Combination of Single-Nucleotide Polymorphisms Is Associated with Interindividual Variability in Cholecalciferol Bioavailability in Healthy Men.Q48260717
The three-factor eating questionnaire to measure dietary restraint, disinhibition and hungerQ48984819
Fatty acids modulate the expression levels of key proteins for cholesterol absorption in Caco-2 monolayerQ49795812
Promoter variant -204A > C of the cholesterol 7α-hydroxylase gene: association with response to plant sterols in humans and increased transcriptional activity in transfected HepG2 cellsQ50069740
Genetic modifiers of folate, vitamin B-12, and homocysteine status in a cross-sectional study of the Canadian populationQ50446187
Lycopene bioavailability is associated with a combination of genetic variants.Q50450036
Single nucleotide polymorphisms related to vitamin B12 serum levels in autoimmune gastritis patients with or without pernicious anaemia.Q50597225
Postprandial whole-body protein metabolism after a meat meal is influenced by chewing efficiency in elderly subjects.Q51008338
Can genetic variability in α-tocopherol bioavailability explain the heterogeneous response to α-tocopherol supplements?Q51314649
Polymorphisms in the CD36/FAT gene are associated with plasma vitamin E concentrations in humans.Q51381935
Oral sensitivity to oleic acid is associated with fat intake and body mass index.Q51438229
Food: a new form of personalised (gut microbiome) medicine for chronic diseases?Q51526680
Postprandial lipemic response is modified by the polymorphism at codon 54 of the fatty acid-binding protein 2 gene.Q51567680
[15N]-labeled pea flour protein nitrogen exhibits good ileal digestibility and postprandial retention in humans.Q51575222
Gustatory mechanisms for the detection of fat.Q52184162
High True Ileal Digestibility but Not Postprandial Utilization of Nitrogen from Bovine Meat Protein in Humans Is Moderately Decreased by High-Temperature, Long-Duration Cooking.Q53379162
Association of L-FABP T94A and MTP I128T polymorphisms with hyperlipidemia in Chinese subjects.Q54174857
Net postprandial utilization of [15N]-labeled milk protein nitrogen is influenced by diet composition in humans.Q54239730
The potential effect of metallothionein 2A -5A/G single nucleotide polymorphism on blood cadmium, lead, zinc and copper levels.Q54358919
The abundance and variety of carbohydrate-active enzymes in the human gut microbiotaQ56562227
Genetic Variants in SGLT1, Glucose Tolerance, and Cardiometabolic RiskQ57025390
FGF21 acts as a negative regulator of bile acid synthesisQ57120005
Intrinsic and Extrinsic Factors Impacting Absorption, Metabolism, and Health Effects of Dietary CarotenoidsQ57177518
Renal polyamine excretion, tubular amino acid reabsorption and molecular genetics in cystinuriaQ57672627
The role of SLC34A2 in intestinal phosphate absorption and phosphate homeostasisQ57808852
P433issue21
P304page(s)e1900677
P577publication date2019-10-01
P1433published inMolecular Nutrition and Food ResearchQ15751861
P1476titleGutSelf: Interindividual Variability in the Processing of Dietary Compounds by the Human Gastrointestinal Tract
P478volume63

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