scholarly article | Q13442814 |
P50 | author | Rachel A. Henry Bonami | Q43108114 |
Rachel E Miles | Q93242694 | ||
P2093 | author name string | Fang Yu | |
Todd D Giorgio | |||
Craig L Duvall | |||
Peggy L Kendall | |||
Elizabeth J Curvino | |||
Meredith A Jackson | |||
Ella N Hoogenboezem | |||
Sean K Bedingfield | |||
Shrusti S Patel | |||
Mitchell E Stokan | |||
P2860 | cites work | Liver immunology and its role in inflammation and homeostasis | Q26750478 |
Knocking down disease: a progress report on siRNA therapeutics | Q28082939 | ||
Correlating animal and human phase Ia/Ib clinical data with CALAA-01, a targeted, polymer-based nanoparticle containing siRNA. | Q30837863 | ||
A combinatorial polymer library approach yields insight into nonviral gene delivery | Q33338185 | ||
Liposome formulations with prolonged circulation time in blood and enhanced uptake by tumors | Q33649082 | ||
Revisit complexation between DNA and polyethylenimine - Effect of uncomplexed chains free in the solution mixture on gene transfection. | Q33740338 | ||
Combinatorial synthesis of chemically diverse core-shell nanoparticles for intracellular delivery | Q33969814 | ||
Delivery of siRNA therapeutics: barriers and carriers | Q34293708 | ||
Enhancing in vivo circulation and siRNA delivery with biodegradable polyethylenimine-graft-polycaprolactone-block-poly(ethylene glycol) copolymers | Q34308149 | ||
Dendritic cells and liver fibrosis | Q34322229 | ||
The modification of siRNA with 3' cholesterol to increase nuclease protection and suppression of native mRNA by select siRNA polyplexes | Q34389925 | ||
A two-stage poly(ethylenimine)-mediated cytotoxicity: implications for gene transfer/therapy | Q34558019 | ||
Dendritic cells and immune regulation in the liver | Q35043807 | ||
siRNA delivery from triblock copolymer micelles with spatially-ordered compartments of PEG shell, siRNA-loaded intermediate layer, and hydrophobic core | Q35115838 | ||
Polycation-siRNA nanoparticles can disassemble at the kidney glomerular basement membrane. | Q35778918 | ||
Breaking up the correlation between efficacy and toxicity for nonviral gene delivery | Q35971611 | ||
Zwitterionic gel encapsulation promotes protein stability, enhances pharmacokinetics, and reduces immunogenicity. | Q36120371 | ||
Combinatorial optimization of PEG architecture and hydrophobic content improves ternary siRNA polyplex stability, pharmacokinetics, and potency in vivo | Q36331202 | ||
Zwitterionic Nanocarrier Surface Chemistry Improves siRNA Tumor Delivery and Silencing Activity Relative to Polyethylene Glycol. | Q36382827 | ||
Odyssey of a cancer nanoparticle: from injection site to site of action | Q36459196 | ||
Membrane and nuclear permeabilization by polymeric pDNA vehicles: efficient method for gene delivery or mechanism of cytotoxicity? | Q36474508 | ||
Toxicity of cationic lipids and cationic polymers in gene delivery | Q36532318 | ||
Delivery of intracellular-acting biologics in pro-apoptotic therapies | Q36588920 | ||
Ex vivo red blood cell hemolysis assay for the evaluation of pH-responsive endosomolytic agents for cytosolic delivery of biomacromolecular drugs. | Q36765566 | ||
CRLX101 nanoparticles localize in human tumors and not in adjacent, nonneoplastic tissue after intravenous dosing. | Q36802373 | ||
Nanoparticle interaction with biological membranes: does nanotechnology present a Janus face? | Q36809026 | ||
Factors affecting the clearance and biodistribution of polymeric nanoparticles. | Q37146591 | ||
Principles of nanoparticle design for overcoming biological barriers to drug delivery | Q37162182 | ||
Cationic nanoparticles induce nanoscale disruption in living cell plasma membranes | Q37365453 | ||
Balancing cationic and hydrophobic content of PEGylated siRNA polyplexes enhances endosome escape, stability, blood circulation time, and bioactivity in vivo | Q37378292 | ||
Sterically stabilized liposomes: improvements in pharmacokinetics and antitumor therapeutic efficacy | Q37650345 | ||
Tumor delivery of macromolecular drugs based on the EPR effect | Q37715368 | ||
Polycation-based nanoparticle delivery of RNAi therapeutics: adverse effects and solutions | Q38026631 | ||
The EPR effect for macromolecular drug delivery to solid tumors: Improvement of tumor uptake, lowering of systemic toxicity, and distinct tumor imaging in vivo | Q38054216 | ||
Biocompatibility of engineered nanoparticles for drug delivery | Q38069385 | ||
Current issues of RNAi therapeutics delivery and development | Q38238806 | ||
Clinical experiences with systemically administered siRNA-based therapeutics in cancer | Q38633261 | ||
Lipophilic siRNA targets albumin in situ and promotes bioavailability, tumor penetration, and carrier-free gene silencing. | Q38663657 | ||
Drugging the 'undruggable' cancer targets | Q38667658 | ||
Immunology in the liver--from homeostasis to disease | Q38693925 | ||
Advances in the delivery of RNA therapeutics: from concept to clinical reality. | Q38706445 | ||
Effect of charge ratio on lipoplex-mediated gene delivery and liver toxicity | Q38816533 | ||
Recent progress in development of siRNA delivery vehicles for cancer therapy | Q38847589 | ||
Introduction of stearoyl moieties into a biocompatible cationic polyaspartamide derivative, PAsp(DET), with endosomal escaping function for enhanced siRNA-mediated gene knockdown. | Q39720008 | ||
Hydrophobic interactions between polymeric carrier and palmitic acid-conjugated siRNA improve PEGylated polyplex stability and enhance in vivo pharmacokinetics and tumor gene silencing | Q39779323 | ||
In vivo pharmacokinetics, tissue distribution and underlying mechanisms of various PEI(-PEG)/siRNA complexes | Q39986907 | ||
Efficient in vivo delivery of siRNA to the liver by conjugation of alpha-tocopherol | Q39999051 | ||
Application of poly(2-(dimethylamino)ethyl methacrylate)-based polyplexes for gene transfer into human ovarian carcinoma cells | Q40380233 | ||
Excess polycation mediates efficient chitosan-based gene transfer by promoting lysosomal release of the polyplexes | Q41933150 | ||
Evasion of the Accelerated Blood Clearance Phenomenon by Coating of Nanoparticles with Various Hydrophilic Polymers | Q42925153 | ||
Intravenous fate of poly(2-(dimethylamino)ethyl methacrylate)-based polyplexes | Q44682521 | ||
In vivo disassembly of IV administered siRNA matrix nanoparticles at the renal filtration barrier | Q44995263 | ||
Stability of siRNA polyplexes from poly(ethylenimine) and poly(ethylenimine)-g-poly(ethylene glycol) under in vivo conditions: effects on pharmacokinetics and biodistribution measured by Fluorescence Fluctuation Spectroscopy and Single Photon Emissi | Q45999838 | ||
Evaluation of proinflammatory cytokine production induced by linear and branched polyethylenimine/plasmid DNA complexes in mice | Q46979772 | ||
Anti-PEG antibodies in the clinic: Current issues and beyond PEGylation | Q47102857 | ||
Selective mTORC2 Inhibitor Therapeutically Blocks Breast Cancer Cell Growth and Survival. | Q52390750 | ||
Targeted polymeric micelles for siRNA treatment of experimental cancer by intravenous injection. | Q53169867 | ||
Actively-targeted polyion complex micelles stabilized by cholesterol and disulfide cross-linking for systemic delivery of siRNA to solid tumors. | Q53525118 | ||
Pre-existing anti-polyethylene glycol antibody reduces the therapeutic efficacy and pharmacokinetics of PEGylated liposomes. | Q55242101 | ||
Block Copolymer Micelles in Nanomedicine Applications | Q57174691 | ||
Effect of polymer structure on micelles formed between siRNA and cationic block copolymer comprising thiols and amidines | Q57184939 | ||
Polymer brush-stabilized polyplex for a siRNA carrier with long circulatory half-life | Q57744083 | ||
Biodegradable Zwitterionic Nanogels with Long Circulation for Antitumor Drug Delivery | Q62273079 | ||
Prolonged circulation time and enhanced accumulation in malignant exudates of doxorubicin encapsulated in polyethylene-glycol coated liposomes | Q72785658 | ||
Amino-modified and lipid-conjugated dicer-substrate siRNA enhances RNAi efficacy | Q83210784 | ||
Accelerated blood clearance phenomenon upon repeated injection of PEG-modified PLA-nanoparticles | Q84295405 | ||
Specific effects of PEGylation on gene delivery efficacy of polyethylenimine: interplay between PEG substitution and N/P ratio | Q84596041 | ||
A brush-polymer conjugate of exendin-4 reduces blood glucose for up to five days and eliminates poly(ethylene glycol) antigenicity | Q89164775 | ||
P304 | page(s) | 245-259 | |
P577 | publication date | 2018-11-10 | |
P1433 | published in | Biomaterials | Q15751139 |
P1476 | title | Dual carrier-cargo hydrophobization and charge ratio optimization improve the systemic circulation and safety of zwitterionic nano-polyplexes | |
P478 | volume | 192 |
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