Screening for Developmental Neurotoxicity at the National Toxicology Program: The Future Is Here

scientific article published on 01 January 2019

Screening for Developmental Neurotoxicity at the National Toxicology Program: The Future Is Here is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.1093/TOXSCI/KFY278
P932PMC publication ID6657567
P698PubMed publication ID30496580

P50authorLinda BirnbaumQ15428834
Jui-Hua HsiehQ59693162
Richard PaulesQ73197449
P2093author name stringPaul M D Foster
Raymond R Tice
Mamta Behl
Nisha S Sipes
Andrew J Shapiro
Kristen Ryan
Nigel J Walker
John R Bucher
Bradley J Collins
Frederick Parham
P2860cites workNeurobehavioural effects of developmental toxicityQ26998967
Freshwater Planarians as an Alternative Animal Model for NeurotoxicologyQ27319602
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A Data Analysis Pipeline Accounting for Artifacts in Tox21 Quantitative High-Throughput Screening AssaysQ30938685
Chemical genomics profiling of environmental chemical modulation of human nuclear receptorsQ33890181
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Regulatory Forum opinion piece: New testing paradigms for reproductive and developmental toxicity--the NTP modified one generation study and OECD 443.Q34577137
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High-content screening assay for identification of chemicals impacting spontaneous activity in zebrafish embryosQ35064824
Meeting report: alternatives for developmental neurotoxicity testingQ35791012
Workgroup report: incorporating in vitro alternative methods for developmental neurotoxicity into international hazard and risk assessment strategiesQ35842533
Neurite outgrowth in human induced pluripotent stem cell-derived neurons as a high-throughput screen for developmental neurotoxicity or neurotoxicityQ35917058
Combination of multiple neural crest migration assays to identify environmental toxicants from a proof-of-concept chemical libraryQ36364780
Acute and developmental behavioral effects of flame retardants and related chemicals in zebrafishQ36623271
Compound selection for in vitro modeling of developmental neurotoxicityQ38015145
Developmental neurotoxicity testing: a path forwardQ38038302
Zebrafish as a systems toxicology model for developmental neurotoxicity testingQ38238589
Expanding the test set: Chemicals with potential to disrupt mammalian brain developmentQ38609808
Adverse outcome pathways: Application to enhance mechanistic understanding of neurotoxicityQ39320908
Editor's Highlight: Comparative Toxicity of Organophosphate Flame Retardants and Polybrominated Diphenyl Ethers to Caenorhabditis elegansQ39448938
Developmental neurotoxicity testing: recommendations for developing alternative methods for the screening and prioritization of chemicals.Q39594231
Use of alternative assays to identify and prioritize organophosphorus flame retardants for potential developmental and neurotoxicity.Q40522904
From the Cover: Developmental Neurotoxicants Disrupt Activity in Cortical Networks on Microelectrode Arrays: Results of Screening 86 Compounds During Neural Network Formation.Q45945253
Developmental exposure to low concentrations of two brominated flame retardants, BDE-47 and BDE-99, causes life-long behavioral alterations in zebrafishQ46303119
Consensus statement on the need for innovation, transition and implementation of developmental neurotoxicity (DNT) testing for regulatory purposesQ49971717
Three-dimensional (3D) tetra-culture brain on chip platform for organophosphate toxicity screeningQ50055399
A high-throughput approach to identify specific neurotoxicants/ developmental toxicants in human neuronal cell function assaysQ50104311
Editor's Highlight: Evaluation of a Microelectrode Array-Based Assay for Neural Network Ontogeny Using Training Set ChemicalsQ50195756
Recommendation on test readiness criteria for new approach methods in toxicology: Exemplified for developmental neurotoxicityQ50421707
OECD/EFSA workshop on developmental neurotoxicity (DNT): The use of non-animal test methods for regulatory purposes.Q50444225
International STakeholder NETwork (ISTNET) for creating a developmental neurotoxicity testing (DNT) roadmap for regulatory purposes.Q50665556
Advancing the science of developmental neurotoxicity (DNT): testing for better safety evaluation.Q50790349
Systematic developmental neurotoxicity assessment of a representative PAH Superfund mixture using zebrafish.Q52327980
Testing for developmental neurotoxicity using a battery of in vitro assays for key cellular events in neurodevelopment.Q52329355
Application of benchmark concentration (BMC) analysis on zebrafish data - a new perspective for quantifying toxicity in alternative animal modelsQ57469635
Teratological and behavioral screening of the National Toxicology Program 91-compound library in zebrafish (Danio rerio)Q58551155
Multi-Behavioral Endpoint Testing of an 87-Chemical Compound Library in Freshwater PlanariansQ89076177
Comparative Analysis of Zebrafish and Planarian Model Systems for Developmental Neurotoxicity Screens Using an 87-Compound LibraryQ90239560
Detection and Prioritization of Developmentally Neurotoxic and/or Neurotoxic Compounds Using ZebrafishQ90303769
Functional and Mechanistic Neurotoxicity Profiling Using Human iPSC-Derived Neural 3D CulturesQ91250348
International Regulatory and Scientific Effort for Improved Developmental Neurotoxicity TestingQ93371604
P433issue1
P921main subjecttoxic encephalopathyQ7830379
P304page(s)6-14
P577publication date2019-01-01
P1433published inToxicological SciencesQ2446966
P1476titleScreening for Developmental Neurotoxicity at the National Toxicology Program: The Future Is Here
P478volume167

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cites work (P2860)
Q90303769Detection and Prioritization of Developmentally Neurotoxic and/or Neurotoxic Compounds Using Zebrafish
Q58107746Heavy metal neurotoxicants induce ALS-linked TDP-43 pathology
Q89752997Potential frameworks to support evaluation of mechanistic data for developmental neurotoxicity outcomes: A symposium report

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