Targeting PIK3CG in Combination with Paclitaxel as a Potential Therapeutic Regimen in Claudin-Low Breast Cancer

scientific article published on 20 April 2020

Targeting PIK3CG in Combination with Paclitaxel as a Potential Therapeutic Regimen in Claudin-Low Breast Cancer is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.2147/CMAR.S250171
P932PMC publication ID7182462
P698PubMed publication ID32368142

P50authorShubing ZhangQ94526129
P2093author name stringHao Yang
Jun Chang
Zhijian Li
Ling Hong
Keli Xu
Yaozhong Liu
Wenrui Ye
Yiwen Pan
P2860cites workIdentification of human triple-negative breast cancer subtypes and preclinical models for selection of targeted therapiesQ29617680
Targeting Met and Notch in the Lfng-deficient, Met-amplified triple-negative breast cancer.Q33631501
PI3Kγ is a molecular switch that controls immune suppressionQ33822173
PI3Kγ mediates kaposi's sarcoma-associated herpesvirus vGPCR-induced sarcomagenesis.Q35207596
Manic fringe promotes a claudin-low breast cancer phenotype through notch-mediated PIK3CG induction.Q35612277
Stress hormones reduce the efficacy of paclitaxel in triple negative breast cancer through induction of DNA damageQ35677932
Expression of miR-200c in claudin-low breast cancer alters stem cell functionality, enhances chemosensitivity and reduces metastatic potentialQ36042570
Autophagy inhibition re-sensitizes pulse stimulation-selected paclitaxel-resistant triple negative breast cancer cells to chemotherapy-induced apoptosisQ36609034
Identification of upregulated phosphoinositide 3-kinase γ as a target to suppress breast cancer cell migration and invasionQ36799499
Predicting drug responsiveness in human cancers using genetically engineered mice.Q37187379
Characterization of cell lines derived from breast cancers and normal mammary tissues for the study of the intrinsic molecular subtypes.Q37321751
Cancer metastasis: Mechanisms of inhibition by melatoninQ38972864
Targeting nonclassical oncogenes for therapy in T-ALL.Q39362097
Mcl-1 and Bcl-2/Bax ratio are associated with treatment response but not with Rai stage in B-cell chronic lymphocytic leukemiaQ44706243
PI3Kgamma is a key regulator of inflammatory responses and cardiovascular homeostasisQ45345832
PTEN Regulates PI(3,4)P2 Signaling Downstream of Class I PI3K.Q47100426
Treg depletion potentiates checkpoint inhibition in claudin-low breast cancerQ47927802
Phosphoinositide 3-Kinase Gamma Inhibition Protects from Anthracycline Cardiotoxicity and Reduces Tumor Growth.Q49953587
Beclin1 enhances cisplatin-induced apoptosis via Bcl-2-modulated autophagy in laryngeal carcinoma cells Hep-2.Q50095882
TRA2A Promoted Paclitaxel Resistance and Tumor Progression in Triple-Negative Breast Cancers via Regulating Alternative Splicing.Q51053007
DPYSL3 modulates mitosis, migration, and epithelial-to-mesenchymal transition in claudin-low breast cancerQ60310878
Knockdown of lncRNA H19 restores chemo-sensitivity in paclitaxel-resistant triple-negative breast cancer through triggering apoptosis and regulating Akt signaling pathwayQ61947586
Autophagy facilitates multidrug resistance development through inhibition of apoptosis in breast cancer cellsQ86538006
Epithelial Paradox: Clinical Significance of Coexpression of E-cadherin and Vimentin With Regard to Invasion and Metastasis of Breast CancerQ88019648
Pre-treatment with the CDK4/6 inhibitor palbociclib improves the efficacy of paclitaxel in TNBC cellsQ90044964
Characteristics, behaviour and role of biomarkers in metastatic triple-negative breast cancerQ90347970
CircCDR1as upregulates autophagy under hypoxia to promote tumor cell survival via AKT/ERK½/mTOR signaling pathways in oral squamous cell carcinomasQ90467633
A small molecule interacts with VDAC2 to block mouse BAK-driven apoptosisQ90576291
Recurrent and metastatic extragastrointestinal stromal tumors of the mesentery with C-KIT and PDGFRA mutations: a case reportQ90624593
Brain metastasis-related microRNAs in patients with advanced breast cancerQ90655998
Synergistic enhancement of apoptosis by coralyne and paclitaxel in combination on MDA-MB-231 a triple-negative breast cancer cell lineQ92577579
Low Dose of Paclitaxel Combined with XAV939 Attenuates Metastasis, Angiogenesis and Growth in Breast Cancer by Suppressing Wnt SignalingQ92641713
Autophagy manipulation as a strategy for efficient anticancer therapies: possible consequencesQ92757487
P275copyright licenseCreative Commons Attribution-NonCommercial 3.0 UnportedQ18810331
P6216copyright statuscopyrightedQ50423863
P4510describes a project that usesImageJQ1659584
P921main subjectpaclitaxelQ423762
P304page(s)2641-2651
P577publication date2020-04-20
P1433published inCancer Management and ResearchQ5031417
P1476titleTargeting PIK3CG in Combination with Paclitaxel as a Potential Therapeutic Regimen in Claudin-Low Breast Cancer
P478volume12

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