Questioning the evidence behind the Saturation Model for testosterone replacement therapy in prostate cancer

scientific article published on 27 April 2020

Questioning the evidence behind the Saturation Model for testosterone replacement therapy in prostate cancer is …
instance of (P31):
review articleQ7318358
scholarly articleQ13442814

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P356DOI10.4111/ICU.2020.61.3.242
P932PMC publication ID7189106
P698PubMed publication ID32377599

P50authorJin Wook KimQ56987070
P2860cites workAdverse Effects of Testosterone Therapy in Adult Men: A Systematic Review and Meta-AnalysisQ22306210
Meta-analysis of incidence rate data in the presence of zero eventsQ30940518
Testosterone dose-response relationships in healthy young men.Q33955919
Testosterone replacement therapy in hypogonadal men at high risk for prostate cancer: results of 1 year of treatment in men with prostatic intraepithelial neoplasiaQ34278601
Testosterone and prostate cancer: an historical perspective on a modern mythQ34552217
Shifting the paradigm of testosterone and prostate cancer: the saturation model and the limits of androgen-dependent growthQ34846764
A triad of telomerase, androgen receptor and early growth response 1 in prostate cancer cells.Q37013269
Guilt by association: a historical perspective on Huggins, testosterone therapy, and prostate cancerQ37189107
Does testosterone therapy increase the risk of prostate cancer?Q37321769
In vitro model systems to study androgen receptor signaling in prostate cancerQ38085294
The effect of testosterone replacement therapy on prostate cancer: a systematic review and meta-analysisQ38180392
The effect of diet-induced insulin resistance on DNA methylation of the androgen receptor promoter in the penile cavernosal smooth muscle of miceQ38449866
Can testosterone therapy be offered to men on active surveillance for prostate cancer? Preliminary resultsQ38573757
Controversies and Advances With Testosterone Therapy: A 40-Year PerspectiveQ38673623
Testosterone Therapy in Men With Prostate CancerQ38683604
Endogenous and exogenous testosterone and the risk of prostate cancer and increased prostate-specific antigen (PSA) level: a meta-analysisQ38700878
Conversion of androgen receptor signaling from a growth suppressor in normal prostate epithelial cells to an oncogene in prostate cancer cells involves a gain of function in c-Myc regulationQ38982717
Factors influencing prostate-specific antigen response among men treated with testosterone therapy for 6 monthsQ40215601
Testosterone and prostate health: debunking myths demands evidence, caution, and good clinical judgmentQ43706693
Studies on prostatic cancer: I. The effect of castration, of estrogen and of androgen injection on serum phosphatases in metastatic carcinoma of the prostate. 1941.Q44018378
Older men are as responsive as young men to the anabolic effects of graded doses of testosterone on the skeletal muscleQ45161400
The Expression of Androgen Receptor and Its Variants in Human Prostate Cancer Tissue according to Disease Status, and Its Prognostic Significance.Q53682998
Shifting the Paradigm of Testosterone Replacement Therapy in Prostate Cancer.Q54970093
Role of Androgen Receptor in Prostate Cancer: A ReviewQ57106160
Androgen receptor levels and androgen contents in the prostate lobes of intact and testosterone-treated Noble ratsQ69874571
Androgen-induced regrowth in the castrated rat ventral prostate: role of 5alpha-reductaseQ73025259
Efficacy and safety study of 1.62% testosterone gel for the treatment of hypogonadal menQ83862092
Testosterone Therapy Can be Given to Men with No Concern that it will Promote Prostate Cancer Development or Progression: ConQ88117792
Testosterone, testosterone therapy and prostate cancerQ90915614
Effect of long term aspirin use on the incidence of prostate cancer: A systematic review and meta-analysisQ93191310
P275copyright licenseCreative Commons Attribution-NonCommercial 4.0 InternationalQ34179348
P433issue3
P921main subjectprostate cancerQ181257
testosteroneQ1318776
testosteroneQ27863114
prostate neoplasmQ56014511
P304page(s)242-249
P577publication date2020-04-27
2020-05-01
P1433published inInvestigative and clinical urologyQ27727133
P1476titleQuestioning the evidence behind the Saturation Model for testosterone replacement therapy in prostate cancer
P478volume61

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Q97527554Letter to the editor: Questioning the evidence behind the Saturation Model for testosterone replacement therapy in prostate cancercites workP2860

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