Acthar Gel (repository corticotropin injection) for persistently active SLE: study design and baseline characteristics from a multicentre, randomised, double-blind, placebo-controlled trial

scientific article published on 21 April 2020

Acthar Gel (repository corticotropin injection) for persistently active SLE: study design and baseline characteristics from a multicentre, randomised, double-blind, placebo-controlled trial is …
instance of (P31):
scholarly articleQ13442814

External links are
P356DOI10.1136/LUPUS-2020-000383
P932PMC publication ID7204552
P698PubMed publication ID32399253

P50authorAnca AskanaseQ91519987
P2093author name stringEnxu Zhao
Richard A Furie
Erin Connolly-Strong
Julie Zhu
P2860cites workACTH protects against glucocorticoid-induced osteonecrosis of boneQ24631407
Astrocytes: new targets of melanocortin 4 receptor actionsQ26865387
Systemic lupus erythematosus.Q53202066
The melanocortin system in control of inflammation.Q55426694
Advances in the treatment of Systemic Lupus Erythematosus: from back to the future, to the future and beyondQ57154870
Glucocorticoids and irreversible damage in patients with systemic lupus erythematosusQ87556958
Immunomodulatory effects of H.P. Acthar Gel on B cell development in the NZB/W F1 mouse model of systemic lupus erythematosusQ87740032
A phase III, randomized, placebo-controlled study of belimumab, a monoclonal antibody that inhibits B lymphocyte stimulator, in patients with systemic lupus erythematosusQ28254310
ACTH: The forgotten therapyQ28258012
Efficacy and safety of belimumab in patients with active systemic lupus erythematosus: a randomised, placebo-controlled, phase 3 trialQ28304807
Efficacy and Safety of Subcutaneous Belimumab in Systemic Lupus Erythematosus: A Fifty-Two-Week Randomized, Double-Blind, Placebo-Controlled StudyQ33698040
Numerical scoring for the BILAG-2004 indexQ34056232
Targeting melanocortin receptors as a novel strategy to control inflammation.Q35682900
Direct effects of HP Acthar Gel on human B lymphocyte activation in vitroQ36218750
Mechanisms of action of adrenocorticotropic hormone and other melanocortins relevant to the clinical management of patients with multiple sclerosisQ36613389
Corticosteroids: do they damage the cardiovascular system?Q36679823
Curbing Inflammation through Endogenous Pathways: Focus on Melanocortin PeptidesQ36877176
Efficacy and tolerability of repository corticotropin injection in patients with persistently active SLE: results of a phase 4, randomised, controlled pilot studyQ37464041
Efficacy and Safety of Epratuzumab in Moderately to Severely Active Systemic Lupus Erythematosus: Results From Two Phase III Randomized, Double-Blind, Placebo-Controlled TrialsQ37633396
Clinical practice. Glucocorticoid-induced bone diseaseQ37898140
Unmet Needs in the Pathogenesis and Treatment of Systemic Lupus Erythematosus.Q39150632
Glucocorticoids act directly on osteoblasts and osteocytes to induce their apoptosis and reduce bone formation and strengthQ40604863
Bone loss is more severe in primary adrenal than in pituitary-dependent Cushing's syndromeQ44807843
A pivotal phase III, randomised, placebo-controlled study of belimumab in patients with systemic lupus erythematosus located in China, Japan and South KoreaQ49359821
Repository corticotropin injection in patients with persistently active SLE requiring corticosteroids: post hoc analysis of results from a two-part, 52-week pilot studyQ49480873
P275copyright licenseCreative Commons Attribution-NonCommercial 4.0 InternationalQ34179348
P6216copyright statuscopyrightedQ50423863
P433issue1
P921main subjectplaceboQ269829
multicenter clinical trialQ6934595
placebo-controlled trialQ108853737
P304page(s)e000383
P577publication date2020-04-21
P1433published inLupus science & medicineQ27725658
P1476titleActhar Gel (repository corticotropin injection) for persistently active SLE: study design and baseline characteristics from a multicentre, randomised, double-blind, placebo-controlled trial
P478volume7

Search more.