Towards an understanding of women's brain aging: the immunology of pregnancy and menopause

scientific article published on 03 June 2020

Towards an understanding of women's brain aging: the immunology of pregnancy and menopause is …
instance of (P31):
scholarly articleQ13442814

External links are
P356DOI10.1016/J.YFRNE.2020.100850
P698PubMed publication ID32504632

P2093author name stringClaudia Barth
Ann-Marie G de Lange
P2860cites workMicrochimerism in Japanese women patients with systemic sclerosisQ78044345
Feto-maternal microchimerism in connective tissue diseasesQ78516511
Changes in serum cytokine concentrations during the menopausal transitionQ79428451
Chimerism occurs in thyroid, lung, skin and lymph nodes of women with sonsQ80841841
The association of luteinizing hormone and follicle-stimulating hormone with cytokines and markers of disease activity in rheumatoid arthritis: a case-control studyQ83906110
Greater depressive symptoms, cognition, and markers of brain aging: Northern Manhattan StudyQ88617860
Role of inflammation and oxidative stress in the etiology of primary ovarian insufficiencyQ88990920
From baby brain to mommy brain: Widespread gray matter gain after giving birthQ89918078
Common brain disorders are associated with heritable patterns of apparent aging of the brainQ90263046
Differential effects of completed and incomplete pregnancies on the risk of Alzheimer diseaseQ90321586
Modulating inflammation for cancer therapyQ91521931
Early and late effects of maternal experience on hippocampal neurogenesis, microglia, and the circulating cytokine milieuQ92069195
The long and short term effects of motherhood on the brainQ92074295
Applying a Women's Health Lens to the Study of the Aging BrainQ92105083
Pregnancy Immunogenetics and Genomics: Implications for Pregnancy-Related Complications and Autoimmune DiseaseQ92225885
The Pregnancy Pickle: Evolved Immune Compensation Due to Pregnancy Underlies Sex Differences in Human DiseasesQ92757840
Decreased effector regulatory T cells and increased activated CD4+ T cells in premature ovarian insufficiencyQ93049323
Male microchimerism in the human female brainQ21134035
Male fetal progenitor cells persist in maternal blood for as long as 27 years postpartumQ24567463
One-year brain atrophy evident in healthy agingQ24642943
FOXP3(+) Treg Cells and Gender Bias in Autoimmune DiseasesQ26781235
Hippocampal plasticity during the peripartum period: influence of sex steroids, stress and ageingQ26862576
The structural biology of oestrogen metabolismQ27009283
Fetal microchimerism in women with breast cancerQ28251536
The genetical evolution of social behaviour. IIQ28256861
Transfer of fetal cells with multilineage potential to maternal tissueQ28270559
A new paradigm for depression in new mothers: the central role of inflammation and how breastfeeding and anti-inflammatory treatments protect maternal mental healthQ28395601
Age-related decline of myelin proteins is highly correlated with activation of astrocytes and microglia in the rat CNSQ28568321
Androgens alter T-cell immunity by inhibiting T-helper 1 differentiationQ28655545
Neuroinflammatory component of gray matter pathology in multiple sclerosisQ29398383
Genome-wide trans-ancestry meta-analysis provides insight into the genetic architecture of type 2 diabetes susceptibilityQ29417007
Brain atrophy in Alzheimer's Disease and agingQ30251935
High consistency of regional cortical thinning in aging across multiple samplesQ30489836
Correlations of Y chromosome microchimerism with disease activity in patients with SLE: analysis of preliminary dataQ30804232
Estrogen- and progesterone-mediated structural neuroplasticity in women: evidence from neuroimaging.Q31047972
B cell subsets in postmenopausal women and the effect of hormone replacement therapyQ31926177
Endocrine factors modulating immune responses in pregnancyQ33611653
Estrogen: a master regulator of bioenergetic systems in the brain and bodyQ33623924
The maternal brain: an organ with peripartal plasticityQ33634903
Onset of progressive phase is an age-dependent clinical milestone in multiple sclerosisQ33643239
APOE predicts amyloid-beta but not tau Alzheimer pathology in cognitively normal agingQ33695738
Cortical abnormalities in adults and adolescents with major depression based on brain scans from 20 cohorts worldwide in the ENIGMA Major Depressive Disorder Working GroupQ33726399
T-cell subsets (Th1 versus Th2).Q33989214
Gender differences in autoimmune diseaseQ34040802
Genetic conflicts in human pregnancyQ34060435
50 years of hormonal contraception-time to find out, what it does to our brainQ34071651
Gender specificity of altered human immune cytokine profiles in agingQ34072272
Lack of evidence of foetal microchimerism in female Spanish patients with systemic sclerosisQ73003135
Antiinflammatory effects of estrogen on microglial activationQ73027691
The immune response during the luteal phase of the ovarian cycle: a Th2-type response?Q73134957
Immune effects of hormone replacement therapy in post-menopausal womenQ73559562
Serum interleukin-6, soluble interleukin-6 receptor and soluble gp130 exhibit different patterns of age- and menopause-related changesQ73617563
The evaluation of determinants of early postpartum low mood: the importance of parity and inter-pregnancy intervalQ73807298
Th2-oriented profile of male offspring T cells present in women with systemic sclerosis and reactive with maternal major histocompatibility complex antigensQ77628805
Inflammation in Alzheimer disease-a brief review of the basic science and clinical literatureQ37982377
Androgen in postmenopausal womenQ37997227
History of oral contraceptive drugs and their use worldwideQ38079343
Childbirths and risk of female predominant and other autoimmune diseases in a population-based Danish cohort.Q38437632
Parity and the risk of autoimmune thyroid disease: a community-based study.Q38442358
Perimenopause as a neurological transition stateQ38501586
A possible role of estrone produced in adipose tissues in modulating postmenopausal bone densityQ38531711
Neuroplasticity in the maternal hippocampus: Relation to cognition and effects of repeated stressQ38539991
Sex differences in Alzheimer risk: Brain imaging of endocrine vs chronologic agingQ38601642
Immunological implications of pregnancy-induced microchimerism.Q38686693
Multiparity improves outcomes after cerebral ischemia in female mice despite features of increased metabovascular riskQ38711384
Inflammatory markers in late pregnancy in association with postpartum depression-A nested case-control studyQ38747140
Associations between specific autoimmune diseases and subsequent dementia: retrospective record-linkage cohort study, UK.Q38751838
Defeating Alzheimer's disease and other dementias: a priority for European science and societyQ38778638
Estrogens, Neuroinflammation, and Neurodegeneration.Q38838452
The importance of studying sex differences in disease: The example of multiple sclerosisQ39015338
Pregnancy leads to long-lasting changes in human brain structureQ39089403
An examination of changes in maternal neuroimmune function during pregnancy and the postpartum periodQ39153376
A survey of neuroimmune changes in pregnant and postpartum female ratsQ39337538
The unique immunological and microbial aspects of pregnancyQ39382358
Claudin-5 as a novel estrogen target in vascular endotheliumQ39775405
Hormonal contraception and the development of autoimmunity: A review of the literatureQ40039972
Hormone therapy, timing of initiation, and cognition in women aged older than 60 years: the REMEMBER pilot study.Q40335153
Significant fetal-maternal hemorrhage after termination of pregnancy: implications for development of fetal cell microchimerism.Q40717942
Lifelong estrogen exposure and cognitive performance in elderly womenQ41618550
Th1-type immunity is incompatible with successful pregnancyQ41632972
Estrogen use, APOE, and cognitive decline: evidence of gene-environment interactionQ41737310
Interferon-gamma-producing T cells, pregnancy, and postpartum relapses of multiple sclerosis.Q43462697
Hormonal and reproductive risk factors for development of systemic lupus erythematosus: results of a population-based, case-control studyQ43505242
Cytokine pattern in postmenopauseQ43911039
Does the use of hormonal contraceptives cause microstructural changes in cerebral white matter? Preliminary results of a DTI and tractography study.Q44021001
Estradiol in vivo regulation of brain mitochondrial proteome.Q44224743
Cumulative estrogen exposure, number of menstrual cycles, and Alzheimer's risk in a cohort of British womenQ44274296
Trends in incidence and mortality in rheumatoid arthritis in Rochester, Minnesota, over a forty-year periodQ44506234
Human thymocytes secrete luteinizing hormone: an autocrine regulator of T-cell proliferationQ44995482
The effect of different doses of micronized 17beta-estradiol on C-reactive protein, interleukin-6, and lipids in older womenQ45042716
17beta-estradiol differentially regulates blood-brain barrier permeability in young and aging female rats.Q45096375
Brain magnetic resonance imaging findings in patients with systemic sclerosisQ46220666
Parity and Risk of Thyroid Autoimmunity Based on the NHANES (2001-2002, 2007-2008, 2009-2010, and 2011-2012).Q46240152
Motherhood and the hormones of pregnancy modify concentrations of hippocampal neuronal dendritic spinesQ46590660
Decrease in hippocampal neurogenesis during pregnancy: a link to immunityQ46637809
Dynamic Brains and the Changing Rules of Neuroplasticity: Implications for Learning and RecoveryQ46760489
Opposite effects of microchimerism on breast and colon cancerQ46884475
Pregnancy-associated progenitor cells differentiate and mature into neurons in the maternal brain.Q34131118
Wired for reproduction: organization and development of sexually dimorphic circuits in the mammalian forebrainQ34132322
Continuous versus cyclic progesterone exposure differentially regulates hippocampal gene expression and functional profilesQ34185639
A dominant negative ERβ splice variant determines the effectiveness of early or late estrogen therapy after ovariectomy in ratsQ34201028
Epigenetic regulation of estrogen-dependent memoryQ34243105
Pregnancy and pregnancy-associated hormones alter immune responses and disease pathogenesisQ34260259
Microchimeric fetal cells play a role in maternal wound healing after pregnancyQ34352689
Estrogen regulation of glucose metabolism and mitochondrial function: therapeutic implications for prevention of Alzheimer's diseaseQ34360055
Microchimerism in recurrent miscarriageQ34455664
Dose and temporal pattern of estrogen exposure determines neuroprotective outcome in hippocampal neurons: therapeutic implicationsQ34558386
Hormonal changes in the menopause transitionQ34644005
Androgens and estrogens modulate the immune and inflammatory responses in rheumatoid arthritisQ34735562
Estrogen anti-inflammatory activity in brain: a therapeutic opportunity for menopause and neurodegenerative diseasesQ34784469
Inflammation and pregnancy: the role of the immune system at the implantation siteQ34806659
The HRT controversy: observational studies and RCTs fall in lineQ34975284
The plasticity of human maternal brain: longitudinal changes in brain anatomy during the early postpartum periodQ35053878
Follicle-stimulating hormone stimulates TNF production from immune cells to enhance osteoblast and osteoclast formationQ35075554
What is normal in normal aging? Effects of aging, amyloid and Alzheimer's disease on the cerebral cortex and the hippocampusQ35129501
Genetic pleiotropy between multiple sclerosis and schizophrenia but not bipolar disorder: differential involvement of immune-related gene lociQ35168836
How immune mechanisms are affected by pregnancyQ35172870
C terminus of Hsc70-interacting protein (CHIP)-mediated degradation of hippocampal estrogen receptor-alpha and the critical period hypothesis of estrogen neuroprotectionQ35198156
Sex hormones modulate brain damage in multiple sclerosis: MRI evidenceQ35485697
White matter hyperintensities on brain magnetic resonance in systemic sclerosisQ35555552
Estrogen and cognition: applying preclinical findings to clinical perspectivesQ35591832
Antigenic challenge in the etiology of autoimmune disease in womenQ35622496
Onset timing, thoughts of self-harm, and diagnoses in postpartum women with screen-positive depression findings.Q35632995
The adaptation of the blood-brain barrier to vascular endothelial growth factor and placental growth factor during pregnancyQ35647966
Estrogens in the nervous system: mechanisms and nonreproductive functionsQ35672515
Hormone concentrations throughout uncomplicated pregnancies: a longitudinal studyQ36067573
White matter injury and microglia/macrophage polarization are strongly linked with age-related long-term deficits in neurological function after stroke.Q36113123
Progesterone and autoimmune diseaseQ36202227
Preliminary evidence that long-term estrogen use reduces white matter loss in agingQ36296643
Menopausal hot flashes and white matter hyperintensitiesQ36355611
Sex differences in the causes and consequences of white matter hyperintensitiesQ46939985
Add Alzheimer's disease to the list of autoimmune diseasesQ47624527
Kynurenic acid is reduced in females and oral contraceptive users: Implications for depressionQ47722395
Reproductive factors and risk of systemic lupus erythematosus: nationwide cohort study in DenmarkQ47846590
Multiparity-induced enhancement of hippocampal neurogenesis and spatial memory depends on ovarian hormone status in middle age.Q48165955
Immune cell circulating subsets are affected by gonadal functionQ48201151
Microglia and Alzheimer's diseaseQ48301324
The maternal 'baby brain' revisitedQ48337951
Systemic sclerosis: brain abnormalities revealed by conventional magnetic resonance imaging and magnetization transfer imagingQ48598100
Differential longitudinal changes in cortical thickness, surface area and volume across the adult life span: regions of accelerating and decelerating change.Q48706099
Selective sparing of brain tissue in postmenopausal women receiving hormone replacement therapyQ48884485
Progesterone attenuates demyelination and microglial reaction in the lysolecithin-injured spinal cordQ50436940
Fetal progenitor cells naturally transferred through pregnancy participate in inflammation and angiogenesis during wound healing.Q50510648
Pregnancy persistently affects memory T cell populations.Q50610830
Fetal microchimerism in the maternal mouse brain: a novel population of fetal progenitor or stem cells able to cross the blood-brain barrier?Q50758919
Long-term prospective study of the influence of estrone levels on events in postmenopausal women with or at high risk for coronary artery disease.Q51355481
3 Tesla MRI detects accelerated hippocampal volume reduction in postmenopausal women.Q51526355
Pregnancy allows the transfer and differentiation of fetal lymphoid progenitors into functional T and B cells in mothers.Q51720614
Lack of association between thyroid autoantibodies and parity in a population study argues against microchimerism as a trigger of thyroid autoimmunity.Q51826332
White matter hyperintensities in the forties: their prevalence and topography in an epidemiological sample aged 44-48.Q51886805
Incidence of AD may decline in the early 90s for men, later for women: The Cache County study.Q51960492
Effect of hormone replacement therapy on post-menopausal changes of lymphocytes and T cell subsets.Q52025730
Reproductive period, endogenous estrogen exposure and dementia incidence among women in Latin America and China; A 10/66 population-based cohort study.Q52681403
Pregnancy is associated with a lower risk of onset and a better prognosis in multiple sclerosis.Q52880959
The discrepancy between observational studies and randomized trials of menopausal hormone therapy: did expectations shape experience?Q52957319
Senile plaques stimulate microglia to release a neurotoxin found in Alzheimer brainQ53201329
Endogenous estrogen levels and Alzheimer's disease among postmenopausal women.Q53233390
The number of pregnancies is a risk factor for Alzheimer's disease.Q53282854
Brain Aging and APOE ε4 Interact to Reveal Potential Neuronal Compensation in Healthy Older Adults.Q53418756
Microchimerism and HLA-compatible relationships of pregnancy in scleroderma.Q53782517
A gender gap in autoimmunity.Q55032884
Androgen-Induced Immunosuppression.Q55357541
Sex differences in autoimmune diseaseQ55970264
Executive summary of the Stages of Reproductive Aging Workshop + 10: addressing the unfinished agenda of staging reproductive agingQ56995376
Women's Pregnancy Life History and Alzheimer's Risk: Can Immunoregulation Explain the Link?Q57174073
Inflammation: Bridging Age, Menopause and APOEε4 Genotype to Alzheimer's DiseaseQ57816569
Sex Hormones in Acquired Immunity and Autoimmune DiseaseQ58583865
Exercise and the Aging Brain: Considerations for Sex DifferencesQ60045415
Increased Alzheimer's risk during the menopause transition: A 3-year longitudinal brain imaging studyQ60303191
Sex differences in Alzheimer disease — the gateway to precision medicineQ60637417
Global, regional, and national burden of Alzheimer's disease and other dementias, 1990-2016: a systematic analysis for the Global Burden of Disease Study 2016Q60641769
Cross-Sectional and Longitudinal MRI Brain Scans Reveal Accelerated Brain Aging in Multiple SclerosisQ64078909
Autoimmune Disease in Women: Endocrine Transition and Risk Across the LifespanQ64081204
Progesterone-Related Immune Modulation of Pregnancy and LaborQ64102042
Study of MRI brain findings and carotid US features in systemic sclerosis patients, relationship with disease parametersQ64111768
Cortical thickness variation of the maternal brain in the first 6 months postpartum: associations with parental self-efficacy.Q64960202
Hormonal changes and mood in the puerperiumQ67766975
The immunological pregnancy protective effect of progesterone is manifested via controlling cytokine productionQ71344081
Effect of pregnancy and hormonal changes on the activity of rheumatoid arthritisQ71750740
Subset-specific effects of sex hormones and pituitary gonadotropins on human lymphocyte proliferation in vitroQ72210255
A universal menopausal syndrome?Q36369113
White Matter Lipids as a Ketogenic Fuel Supply in Aging Female Brain: Implications for Alzheimer's Disease.Q36437623
The otherness of self: microchimerism in health and diseaseQ36450729
Fetal microchimerism and maternal health: a review and evolutionary analysis of cooperation and conflict beyond the wombQ36461785
Parity and All-cause Mortality in Women and Men: A Dose-Response Meta-Analysis of Cohort StudiesQ36499602
Menopause leads to elevated expression of macrophage-associated genes in the aging frontal cortex: rat and human studies identify strikingly similar changes.Q36572180
Relationship Between Clinical and Immunological Features with Magnetic Resonance Imaging Abnormalities in Female Patients with Neuropsychiatric Systemic Lupus ErythematosusQ36720077
Estrogen action in neuroprotection and brain inflammation.Q36721776
Reproductive and menopausal factors and risk of systemic lupus erythematosus in womenQ36773713
Very old women at highest risk of dementia and Alzheimer's disease: incidence data from the Kungsholmen Project, Stockholm.Q36843772
Microchimerism in the human brain: more questions than answersQ36846218
Sex differences in Alzheimer's disease and other dementiasQ36893692
Estrogen and CD4+ T cellsQ36925326
Reproduction-induced neuroplasticity: natural behavioural and neuronal alterations associated with the production and care of offspringQ37081752
Postmenopausal hormone therapy and regional brain volumes: the WHIMS-MRI StudyQ37180441
Longitudinal pattern of regional brain volume change differentiates normal aging from MCI.Q37213702
Sub-threshold depressive symptoms and brain structure: A magnetic resonance imaging study within the Whitehall II cohortQ37255464
Essential role of estrogen for improvements in vascular endothelial function with endurance exercise in postmenopausal womenQ37275947
Effects of hormone therapy on brain structure: A randomized controlled trialQ37280188
Number of children is associated with neuropathology of Alzheimer's disease in womenQ37283496
Early decline in glucose transport and metabolism precedes shift to ketogenic system in female aging and Alzheimer's mouse brain: implication for bioenergetic interventionQ37296893
In-vivo Dynamics of the Human Hippocampus across the Menstrual CycleQ37319113
Th1 and Th2 responses: what are they?Q37350671
Multimodal population brain imaging in the UK Biobank prospective epidemiological studyQ37378043
Interbirth intervals: Intrafamilial, intragenomic and intrasomatic conflictQ37566670
Higher risk of progression to dementia in mild cognitive impairment cases who revert to normalQ37593256
The implications of autoimmunity and pregnancyQ37661793
Influence of different estrogens on neuroplasticity and cognition in the hippocampusQ37681138
The role of pregnancy-associated hormones in the development and function of regulatory B cellsQ37689363
Contribution of systemic inflammation to chronic neurodegenerationQ37774280
Fetal microchimerism as an explanation of diseaseQ37823203
Molecular mechanisms involved in the regulation of neuritogenesis by estradiol: Recent advances.Q37942434
Alzheimer's disease, autoimmunity and inflammation. The good, the bad and the uglyQ37945426
Menopause in patients with autoimmune diseasesQ37961466
Immunology and the menstrual cycle.Q37966543
P304page(s)100850
P577publication date2020-06-03
P1433published inFrontiers in NeuroendocrinologyQ15716620
P1476titleTowards an understanding of women's brain aging: the immunology of pregnancy and menopause

Reverse relations

Q98243020The maternal brain: Region-specific patterns of brain aging are traceable decades after childbirthcites workP2860

Search more.