FTY720 Regulates Mitochondria Biogenesis in Dendritic Cells to Prevent Kidney Ischemic Reperfusion Injury

scientific article published on 23 June 2020

FTY720 Regulates Mitochondria Biogenesis in Dendritic Cells to Prevent Kidney Ischemic Reperfusion Injury is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.3389/FIMMU.2020.01278
P932PMC publication ID7328774
P698PubMed publication ID32670281

P2093author name stringAmandeep Bajwa
Canan Kuscu
Valeria Mas
Daniel Maluf
Cem Kuscu
LiPing Huang
Liza Makowski
Maria Namwanje
James D Eason
Kailo Schlegel
Thomas V Rousselle
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Activation of sphingosine-1-phosphate 1 receptor in the proximal tubule protects against ischemia-reperfusion injuryQ30432124
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Immune mechanisms and novel pharmacological therapies of acute kidney injuryQ30434767
Regulatory T cells suppress innate immunity in kidney ischemia-reperfusion injuryQ30435312
IL-17 produced by neutrophils regulates IFN-gamma-mediated neutrophil migration in mouse kidney ischemia-reperfusion injuryQ30437432
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CX3CR1+ interstitial dendritic cells form a contiguous network throughout the entire kidney.Q33246091
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Equilibrative nucleoside transporter 1 (ENT1) regulates postischemic blood flow during acute kidney injury in miceQ35698980
Inhibition of sphingosine 1-phosphate receptor 2 protects against renal ischemia-reperfusion injuryQ35715879
Topographical and biological evidence revealed FTY720-mediated anergy-polarization of mouse bone marrow-derived dendritic cells in vitroQ36000945
Identification of the CD4(+) T cell as a major pathogenic factor in ischemic acute renal failureQ36169286
Commitment to glycolysis sustains survival of NO-producing inflammatory dendritic cells.Q36177914
Sphingosine 1-phosphate and its receptors: an autocrine and paracrine networkQ36184401
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Local application of FTY720 to the lung abrogates experimental asthma by altering dendritic cell functionQ38904716
Renal ischemia-reperfusion injury: renal dendritic cells loudly sound the alarm.Q53563325
Prolongation of heart allograft survival by immature dendritic cells generated from recipient type bone marrow progenitors.Q53874628
Analysis of mtDNA/nDNA Ratio in Mice.Q54878977
Biodistribution and vaccine efficiency of murine dendritic cells are dependent on the route of administrationQ57779785
Mesenchymal stem cells and their mitochondrial transfer: a double-edged sword.Q64972643
FTY720 application following isolated warm liver ischemia improves long-term survival and organ protection in a mouse modelQ79959742
Signals from type 1 sphingosine 1-phosphate receptors enhance adult mouse cardiac myocyte survival during hypoxiaQ80980910
FTY720 for treatment of ischemia-reperfusion injury following complete renal ischemia in C57/BL6 miceQ83220017
Dendritic Cells As Inducers of Peripheral ToleranceQ88820708
Tacrolimus in combination with FTY720--an analysis of renal and blood parametersQ95814552
Sphingosine kinase 1 protects against renal ischemia-reperfusion injury in mice by sphingosine-1-phosphate1 receptor activationQ39488891
The immune modulator FTY720 targets sphingosine 1-phosphate receptorsQ40736684
Extracellular export of sphingosine kinase-1 enzyme. Sphingosine 1-phosphate generation and the induction of angiogenic vascular maturationQ40763807
Mitochondrial transfer from bone-marrow-derived stromal cells to pulmonary alveoli protects against acute lung injuryQ42128038
Mouse lines with photo-activatable mitochondria to study mitochondrial dynamicsQ42257935
Fingolimod additionally acts as immunomodulator focused on the innate immune system beyond its prominent effects on lymphocyte recirculationQ42320254
Adoptive transfer of FTY720-treated immature BMDCs significantly prolonged cardiac allograft survivalQ43034429
FTY720, a novel immunosuppressive agent with insulinotropic activity, prolongs graft survival in a mouse islet transplantation modelQ43552670
First human trial of FTY720, a novel immunomodulator, in stable renal transplant patientsQ43931513
Long-term islet graft survival in streptozotocin- and autoimmune-induced diabetes models by immunosuppressive and potential insulinotropic agent FTY720.Q44002416
FTY720: a novel approach to the treatment of hepatic ischemia-reperfusion injuryQ44101254
FTY720 pretreatment reduces warm hepatic ischemia reperfusion injury through inhibition of T-lymphocyte infiltrationQ44188438
Prevention of autoimmune diabetes by FTY720 in nonobese diabetic miceQ44260906
FTY720 for treatment of ischemia-reperfusion injury following complete renal ischemia; impact on long-term survival and T-lymphocyte tissue infiltrationQ44299688
Immunosuppression with FTY720 and cyclosporine A inhibits rejection of adult porcine islet xenografts in ratsQ44419307
FTY720 reduces T-cell recruitment into murine intestinal allograft and prevents activation of graft-infiltrating cellsQ44469232
The effect of immunomodulators on prevention of autoimmune diabetes is stage dependent: FTY720 prevents diabetes at three different stages in the diabetes-resistant biobreeding rat.Q44813941
Selective sphingosine 1-phosphate 1 receptor activation reduces ischemia-reperfusion injury in mouse kidneyQ44916450
FTY720 impairs necrosis development after ischemia-reperfusion injuryQ44934183
Design of clinical trials in acute kidney injury: a report from an NIDDK workshop--prevention trialsQ44974183
Dynamin-Related Protein 1 Deficiency Promotes Recovery from AKI.Q45071365
FTY720 attenuates hepatic ischemia-reperfusion injury in normal and cirrhotic livers.Q45214556
The immunomodulator FTY720 interferes with effector functions of human monocyte-derived dendritic cells.Q45229482
FTY720 prevents renal T-cell infiltration after ischemia/reperfusion injuryQ46420521
Transient FTY720 treatment promotes immune-mediated clearance of a chronic viral infection.Q46428828
Prevention and cure of autoimmune diabetes in nonobese diabetic mice by continuous administration of FTY720.Q46478164
The sphingosine-1-phosphate receptor agonist FTY720 modulates dendritic cell trafficking in vivoQ46741854
Vitamin D3 Induces Tolerance in Human Dendritic Cells by Activation of Intracellular Metabolic PathwaysQ49160110
P275copyright licenseCreative Commons Attribution 4.0 InternationalQ20007257
P6216copyright statuscopyrightedQ50423863
P304page(s)1278
P577publication date2020-06-23
P1433published inFrontiers in ImmunologyQ27723748
P1476titleFTY720 Regulates Mitochondria Biogenesis in Dendritic Cells to Prevent Kidney Ischemic Reperfusion Injury
P478volume11

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