A review of therapeutic options for managing the metabolic aspects of polycystic ovary syndrome

scientific article published on 06 July 2020

A review of therapeutic options for managing the metabolic aspects of polycystic ovary syndrome is …
instance of (P31):
scholarly articleQ13442814

External links are
P356DOI10.1177/2042018820938305
P932PMC publication ID7338645
P698PubMed publication ID32670541

P50authorMohammed Altigani AbdallaQ97521499
P2093author name stringThozhukat Sathyapalan
Harshal Deshmukh
Stephen Atkin
P2860cites workReduction in the Incidence of Type 2 Diabetes with Lifestyle Intervention or MetforminQ22250892
Lifestyle changes in women with polycystic ovary syndromeQ24234000
MicroRNA genes are transcribed by RNA polymerase IIQ24562649
The effects of a low-carbohydrate, ketogenic diet on the polycystic ovary syndrome: a pilot studyQ25257236
Naltrexone HCI/bupropion HCI for chronic weight management in obese adults: patient selection and perspectivesQ26746239
Bupropion: a systematic review and meta-analysis of effectiveness as an antidepressantQ26747727
Imeglimin: A Potential New Multi-Target Drug for Type 2 DiabetesQ26800961
Dyslipidemia in women with polycystic ovary syndromeQ27025695
Endothelial function and its relationship to leptin, homocysteine, and insulin resistance in lean and overweight eumenorrheic women and PCOS patients: a pilot studyQ46607817
A comparison between rimonabant and metformin in reducing biochemical hyperandrogenaemia and insulin resistance in patients with polycystic ovary syndrome (PCOS): a randomized open-label parallel study.Q46646075
Myo-inositol administration positively affects hyperinsulinemia and hormonal parameters in overweight patients with polycystic ovary syndromeQ46706686
The polycystic ovary syndrome associated with morbid obesity may resolve after weight loss induced by bariatric surgeryQ46724489
Imeglimin normalizes glucose tolerance and insulin sensitivity and improves mitochondrial function in liver of a high-fat, high-sucrose diet mice modelQ46791363
Randomized trial of lifestyle modification and pharmacotherapy for obesityQ46807914
Effect of hypocaloric diet plus sibutramine treatment on hormonal and metabolic features in overweight and obese women with polycystic ovary syndrome: a randomized, 24-week studyQ46856627
The effect of atorvastatin on pancreatic beta cell requirement in women with polycystic ovary syndromeQ47143029
A novel glucagon-like peptide-1/glucagon receptor dual agonist exhibits weight-lowering and diabetes-protective effectsQ47196326
Effect of sibutramine on weight reduction in women with polycystic ovary syndrome: a randomized, double-blind, placebo-controlled trialQ47281414
Insulin sensitivity after metformin suspension in normal-weight women with polycystic ovary syndromeQ47287008
Exercise without weight loss is an effective strategy for obesity reduction in obese individuals with and without Type 2 diabetesQ47383540
The Role of Glucagon in the Pathophysiology and Treatment of Type 2 DiabetesQ47747717
A rationally designed monomeric peptide triagonist corrects obesity and diabetes in rodentsQ48246762
DPP4 INHIBITOR SITAGLIPTIN AS A POTENTIAL TREATMENT OPTION IN METFORMIN-INTOLERANT OBESE WOMEN WITH POLYCYSTIC OVARY SYNDROME: A PILOT RANDOMIZED STUDY.Q49964159
Vitamin B12 deficiency and the knowledge and practice of physicians regarding screening for vitamin B12 deficiency among type 2 diabetic patients on metformin in selected hospitals in Riyadh, Saudi ArabiaQ92969166
Dapagliflozin and Cardiovascular Outcomes in Type 2 DiabetesQ92980564
LY3298176, a novel dual GIP and GLP-1 receptor agonist for the treatment of type 2 diabetes mellitus: From discovery to clinical proof of conceptQ93349907
Biogenesis of small RNAs in animalsQ27861013
MicroRNAs: genomics, biogenesis, mechanism, and functionQ27861070
Effects of Inositol(s) in Women with PCOS: A Systematic Review of Randomized Controlled TrialsQ28073603
Inositol Treatment and ART Outcomes in Women with PCOSQ28077261
The widespread regulation of microRNA biogenesis, function and decayQ28131796
A systematic assessment of cardiovascular outcomes in the saxagliptin drug development program for type 2 diabetesQ28282265
Robust anti-obesity and metabolic effects of a dual GLP-1/glucagon receptor peptide agonist in rodents and non-human primatesQ30368984
Pharmacological and lifestyle interventions to prevent or delay type 2 diabetes in people with impaired glucose tolerance: systematic review and meta-analysisQ30829257
Sibutramine treatment in obesity: predictors of weight loss including rorschach personality dataQ33195173
Statins in the treatment of polycystic ovary syndromeQ33789151
Hyperinsulinemia in polycystic ovary syndrome correlates with increased cardiovascular risk independent of obesityQ33886379
Endocannabinoid receptor blockade reduces alanine aminotransferase in polycystic ovary syndrome independent of weight loss.Q33908763
Favourable metabolic effects of a eucaloric lower-carbohydrate diet in women with PCOS.Q33952149
The effect of myoinositol supplementation on insulin resistance in patients with gestational diabetesQ34026140
Urinary chiro- and myo-inositol levels as a biological marker for type 2 diabetes mellitus.Q34033525
The effect of liraglutide on weight loss in women with polycystic ovary syndrome: an observational studyQ34091483
Effect of sibutramine on cardiovascular outcomes in overweight and obese subjectsQ34136304
Effects of a eucaloric reduced-carbohydrate diet on body composition and fat distribution in women with PCOS.Q34314979
Polycystic ovary syndrome: a review of treatment options with a focus on pharmacological approachesQ34364053
Semaglutide and Cardiovascular Outcomes in Patients with Type 2 DiabetesQ34540403
A randomized, phase 3 trial of naltrexone SR/bupropion SR on weight and obesity-related risk factors (COR-II)Q34585609
Empagliflozin, Cardiovascular Outcomes, and Mortality in Type 2 DiabetesQ34673134
Orlistat in polycystic ovarian syndrome reduces weight with improvement in lipid profile and pregnancy ratesQ34975539
Sodium-glucose cotransporter 2 inhibitors for type 2 diabetes: a systematic review and meta-analysisQ34985373
The psychiatric side-effects of rimonabantQ34990771
Lifestyle modification programs in polycystic ovary syndrome: systematic review and meta-analysis.Q35007744
The effects of treatment with liraglutide on atherothrombotic risk in obese young women with polycystic ovary syndrome and controlsQ35312833
Weight loss with naltrexone SR/bupropion SR combination therapy as an adjunct to behavior modification: the COR-BMOD trial.Q35695148
Safety and tolerability of sitagliptin in patients with type 2 diabetes: a pooled analysisQ42209597
Metformin improves endothelial function and carotid intima media thickness in patients with PCOS.Q42474494
Naltrexone effect on pulsatile GnRH therapy for ovulation induction in polycystic ovary syndrome: a pilot prospective studyQ42508741
Effect of naltrexone plus bupropion on weight loss in overweight and obese adults (COR-I): a multicentre, randomised, double-blind, placebo-controlled, phase 3 trialQ42950914
Mechanism of action of DPP-4 inhibitors--new insightsQ43235398
Atorvastatin pretreatment augments the effect of metformin in patients with polycystic ovary syndrome (PCOS).Q43291794
Myo-inositol may prevent gestational diabetes in PCOS womenQ43429253
Effects of metformin on ovulation rate, hormonal and metabolic profiles in women with clomiphene-resistant polycystic ovaries: a randomized, double-blinded placebo-controlled trialQ43688567
Metformin in women with PCOS, prosQ43852376
Effects of orlistat on fat-soluble vitamins in obese adolescentsQ44069742
Empagliflozin improves glycaemic and weight control as add-on therapy to pioglitazone or pioglitazone plus metformin in patients with type 2 diabetes: a 24-week, randomized, placebo-controlled trialQ44251536
Relation of intra-abdominal fat distribution to metabolic disorders in nonobese patients with polycystic ovary syndromeQ44473192
Effects of dapagliflozin on body weight, total fat mass, and regional adipose tissue distribution in patients with type 2 diabetes mellitus with inadequate glycemic control on metforminQ44653784
Effect of the insulin sensitizer pioglitazone on insulin resistance, hyperandrogenism, and ovulatory dysfunction in women with polycystic ovary syndromeQ45006023
Orlistat is as beneficial as metformin in the treatment of polycystic ovarian syndrome.Q45145839
Association of polycystic ovary syndrome with cardiovascular risk factors.Q45917076
Effect of rimonabant and metformin on glucose-dependent insulinotropic polypeptide and glucagon-like peptide-1 in obese women with polycystic ovary syndrome.Q45986103
Metformin maintains the weight loss and metabolic benefits following rimonabant treatment in obese women with polycystic ovary syndrome (PCOS).Q46172452
The effect of atorvastatin in patients with polycystic ovary syndrome: a randomized double-blind placebo-controlled study.Q46305285
Naltrexone treatment in clomiphene resistant women with polycystic ovary syndromeQ46473099
Metformin and weight loss in obese women with polycystic ovary syndrome: comparison of dosesQ46484240
Effect of metformin, orlistat and pioglitazone treatment on mean insulin resistance and its biological variability in polycystic ovary syndrome.Q46545539
Incretin levels in polycystic ovary syndrome.Q46568299
A two-year randomized trial of obesity treatment in primary care practiceQ35766121
SGLT-2 Inhibitors: A New Mechanism for Glycemic ControlQ35906490
Recent advances in the treatment of polycystic ovary syndromeQ35906966
Defining the role of bariatric surgery in polycystic ovarian syndrome patientsQ35906974
Prevalence and characteristics of the metabolic syndrome in women with polycystic ovary syndromeQ35995837
Liraglutide and Cardiovascular Outcomes in Type 2 DiabetesQ36050559
Medical management of metabolic dysfunction in PCOS.Q36132055
Increased expression of circulating miRNA-93 in women with polycystic ovary syndrome may represent a novel, non-invasive biomarker for diagnosisQ36298211
Evidence for statin therapy in polycystic ovary syndromeQ36327934
D-chiro-inositol metabolism in diabetes mellitusQ36626417
Quality of life and psychological well being in polycystic ovary syndromeQ36835266
Glucose intolerance in polycystic ovary syndrome--a position statement of the Androgen Excess Society.Q37023259
Role of diet in the treatment of polycystic ovary syndrome.Q37119729
Efficacy and safety of the human glucagon-like peptide-1 analog liraglutide in combination with metformin and thiazolidinedione in patients with type 2 diabetes (LEAD-4 Met+TZD).Q37235840
HMG-CoA reductase inhibitors: do they have potential in the treatment of polycystic ovary syndrome?Q37253000
Effects of naltrexone sustained-release/bupropion sustained-release combination therapy on body weight and glycemic parameters in overweight and obese patients with type 2 diabetesQ37331171
Treatment of obesity in polycystic ovary syndrome: a position statement of the Androgen Excess and Polycystic Ovary Syndrome Society.Q37343173
Mechanism of action of inhibitors of dipeptidyl-peptidase-4 (DPP-4).Q37595940
Adipose tissue, metabolic syndrome and polycystic ovary syndrome: from pathophysiology to treatmentQ37631759
The physiologic role of incretin hormones: clinical applications.Q37728788
The Effect of Low Carbohydrate Diets on Fertility Hormones and Outcomes in Overweight and Obese Women: A Systematic Review.Q37729636
Effects of the SGLT2 inhibitor dapagliflozin on HDL cholesterol, particle size, and cholesterol efflux capacity in patients with type 2 diabetes: a randomized placebo-controlled trialQ37736727
Exercise therapy in polycystic ovary syndrome: a systematic reviewQ37787632
Polycystic ovary syndrome: etiology, pathogenesis and diagnosisQ37832125
Dyslipidemia in PCOS.Q37971240
Insulin resistance: a significant risk factor of endometrial cancerQ37997180
Metabolic effects of SGLT-2 inhibitors beyond increased glucosuria: A review of the clinical evidenceQ38305698
Comparison of the effect between pioglitazone and metformin in treating patients with PCOS:a meta-analysis.Q38645244
A systematic review of GLP-1 agonists on the metabolic syndrome in women with polycystic ovariesQ38667575
Canagliflozin and Cardiovascular and Renal Events in Type 2 DiabetesQ38729780
The New Biology and Pharmacology of Glucagon.Q38919742
Bariatric surgery for obesity and metabolic disorders: state of the art.Q39023968
Risk of atherosclerosis in women with polycystic ovary syndrome: a study from South IndiaQ40109816
Pioglitazone-induced congestive heart failure and pulmonary edema in a patient with preserved ejection fractionQ40166604
PPAR-gamma: adipogenic regulator and thiazolidinedione receptorQ41755813
Ovarian function and metabolic factors in women with oligomenorrhea treated with metformin in a randomized double blind placebo-controlled trialQ42166214
Identification, assessment, and management of overweight and obesity: summary of updated NICE guidance.Q50610497
Glucagon-Like Peptide-1 (GLP-1) Receptor Agonists in the Treatment of Obese Women with Polycystic Ovary Syndrome.Q51244187
Imeglimin, a novel glimin oral antidiabetic, exhibits a good efficacy and safety profile in type 2 diabetic patients.Q51357963
A treatment strategy implementing combination therapy with sitagliptin and metformin results in superior glycaemic control versus metformin monotherapy due to a low rate of addition of antihyperglycaemic agents.Q51373947
Total cholesterol, high density lipoprotein and triglyceride for cardiovascular disease in elderly patients treated with metformin.Q51480546
Improvement in endocrine and ovarian function during dietary treatment of obese women with polycystic ovary syndromeQ51607514
Empagliflozin monotherapy with sitagliptin as an active comparator in patients with type 2 diabetes: a randomised, double-blind, placebo-controlled, phase 3 trial.Q51748822
The Sustained Effects of a Dual GIP/GLP-1 Receptor Agonist, NNC0090-2746, in Patients with Type 2 Diabetes.Q51832665
Recommendations from the international evidence-based guideline for the assessment and management of polycystic ovary syndromeQ58836759
Recommendations from the international evidence-based guideline for the assessment and management of polycystic ovary syndromeQ58836764
Metabolic effects of glucagon in humansQ60944099
Dietary Composition in the Treatment of Polycystic Ovary Syndrome: A Systematic Review to Inform Evidence-Based GuidelinesQ61958552
Canagliflozin and Renal Outcomes in Type 2 Diabetes and NephropathyQ63170509
The Effect of Exenatide on Cardiovascular Risk Markers in Women With Polycystic Ovary SyndromeQ64084410
Emerging Role of SGLT-2 Inhibitors for the Treatment of ObesityQ64232819
Exercise, or exercise and diet for the management of polycystic ovary syndrome: a systematic review and meta-analysisQ64237430
Atorvastatin reduces malondialdehyde concentrations in patients with polycystic ovary syndrome.Q64951371
Differences in clinical and endocrine features between obese and non-obese subjects with polycystic ovary syndrome: an analysis of 263 consecutive casesQ67294340
Sibutramine reduces food intake in non-dieting women with obesityQ74397262
Polycystic ovary syndrome: symptomatology, pathophysiology, and epidemiologyQ77690927
The metabolic syndrome in polycystic ovary syndromeQ79783210
Effective treatment of polycystic ovarian syndrome with Roux-en-Y gastric bypassQ80151319
Metformin versus lifestyle changes in treating women with polycystic ovary syndromeQ83395696
The incretin effect and secretion in obese and lean women with polycystic ovary syndrome: a pilot studyQ84357802
Atorvastatin therapy decreases androstenedione and dehydroepiandrosterone sulphate concentrations in patients with polycystic ovary syndrome: randomized controlled studyQ85043105
Pharmacologic and Pharmacodynamic Equivalence of 2 Formulations of OrlistatQ88369357
Effects of orlistat on serum androgen levels among iranian obese women with polycystic ovarian syndromeQ88662229
Effects of a ketogenic diet in overweight women with polycystic ovary syndromeQ89905987
Vitamin B12 deficiency and diabetic neuropathy in patients taking metformin: a cross-sectional studyQ90097847
Sitagliptin Decreases Visceral Fat and Blood Glucose in Women With Polycystic Ovarian SyndromeQ90140092
Effects of dipeptidyl peptidase-4 inhibitors on transforming growth factor-β1 signal transduction pathways in the ovarian fibrosis of polycystic ovary syndrome ratsQ90266880
Evaluation of vitamin B12 monitoring in patients on metformin in urban ambulatory care settingsQ90582305
Molecular Mechanisms by Which Imeglimin Improves Glucose HomeostasisQ90672550
The clinical potential of circulating microRNAs in obesityQ90703773
The effects of treatment with liraglutide on quality of life and depression in young obese women with PCOS and controlsQ90840367
Discovering metformin-induced vitamin B12 deficiency in patients with type 2 diabetes in primary careQ90939918
Gastric bypass versus sleeve gastrectomy in patients with type 2 diabetes (Oseberg): a single-centre, triple-blind, randomised controlled trialQ91069220
Expression of microRNA in follicular fluid in women with and without PCOSQ91198889
The influence of orlistat, metformin and diet on serum levels of insulin-like growth factor-1 in obeses women with and without insulin resistanceQ91229039
Molecular mechanisms by which SGLT2 inhibitors can induce insulin sensitivity in diabetic milieu: A mechanistic reviewQ91440606
Effect of Orlistat Versus Metformin in Various Aspects of Polycystic Ovarian Syndrome: A Systematic Review of Randomized Control TrialsQ91495531
The Effect of Atorvastatin (and Subsequent Metformin) on Adipose Tissue Acylation-Stimulatory-Protein Concentration and Inflammatory Biomarkers in Overweight/Obese Women With Polycystic Ovary SyndromeQ91782126
Long-term efficacy of metformin in overweight-obese PCOS: longitudinal follow-up of retrospective cohortQ91916654
Metformin for ovulation induction (excluding gonadotrophins) in women with polycystic ovary syndromeQ92038416
Effects of empagliflozin on metabolic parameters in polycystic ovary syndrome: A randomized controlled studyQ92331782
Polycystic Ovary Syndrome: Pathophysiology, Presentation, and Treatment With Emphasis on Adolescent GirlsQ92437260
Molecular mechanisms by which GLP-1 RA and DPP-4i induce insulin sensitivityQ92698672
GLP-1 receptor agonists versus metformin in PCOS: a systematic review and meta-analysisQ92958714
P275copyright licenseCreative Commons Attribution-NonCommercial 4.0 InternationalQ34179348
P6216copyright statuscopyrightedQ50423863
P921main subjectpolycystic ovary syndromeQ500816
polycystic ovaryQ5547896
P304page(s)2042018820938305
P577publication date2020-07-06
P1433published inTherapeutic advances in endocrinology and metabolismQ26853790
P1476titleA review of therapeutic options for managing the metabolic aspects of polycystic ovary syndrome
P478volume11

Search more.