Androgen-Mediated Anti-inflammatory Cellular Processes as Therapeutic Targets in Lupus

scientific article published on 23 June 2020

Androgen-Mediated Anti-inflammatory Cellular Processes as Therapeutic Targets in Lupus is …
instance of (P31):
scholarly articleQ13442814
review articleQ7318358

External links are
P356DOI10.3389/FIMMU.2020.01271
P932PMC publication ID7324484
P698PubMed publication ID32655565

P2093author name stringJessica M Jones
Trine N Jørgensen
P2860cites workMyeloid-derived suppressor cells as regulators of the immune systemQ28131637
Bone marrow stromal cells mediate androgenic suppression of B lymphocyte developmentQ28365790
CD19(+)CD24(hi)CD38(hi) B cells exhibit regulatory capacity in healthy individuals but are functionally impaired in systemic Lupus Erythematosus patientsQ34093165
Characterization of a rare IL-10-competent B-cell subset in humans that parallels mouse regulatory B10 cells.Q34144779
Dehydroepiandrosterone treatment of women with mild-to-moderate systemic lupus erythematosus: a multicenter randomized, double-blind, placebo-controlled trialQ34158711
Plasmacytoid dendritic cell interferon-α production to R-848 stimulation is decreased in male infants.Q34329421
From Monocytes to M1/M2 Macrophages: Phenotypical vs. Functional DifferentiationQ34359869
An open study of dehydroepiandrosterone in systemic lupus erythematosusQ34725009
Gonadectomy of male BALB/c mice increases Tim-3(+) alternatively activated M2 macrophages, Tim-3(+) T cells, Th2 cells and Treg in the heart during acute coxsackievirus-induced myocarditisQ35143201
Animal Models of Interferon Signature Positive LupusQ35686914
Interleukin-6 exacerbates glomerulonephritis in (NZB x NZW)F1 miceQ35833886
Androgen receptor modulates Foxp3 expression in CD4+CD25+Foxp3+ regulatory T-cellsQ36063781
A Regulatory Feedback between Plasmacytoid Dendritic Cells and Regulatory B Cells Is Aberrant in Systemic Lupus ErythematosusQ36718239
Activated renal macrophages are markers of disease onset and disease remission in lupus nephritisQ36985612
IFN-γ differentially regulates subsets of Gr-1(+)CD11b(+) myeloid cells in chronic inflammation.Q39624968
TLR7 ligands induce higher IFN-alpha production in females.Q40247926
Low plasma androgens in women with systemic lupus erythematosusQ41331741
Patients with systemic lupus erythematosus and secondary antiphospholipid syndrome have decreased numbers of circulating CD4⁺CD25⁺Foxp3⁺ Treg and CD3⁻CD19⁺ B cellsQ41920666
Forkhead box p3+ regulatory T cell underlies male resistance to experimental type 2 autoimmune hepatitisQ43128400
Effects of dehydroepiandrosterone on fatigue and well-being in women with quiescent systemic lupus erythematosus: a randomised controlled trialQ43255461
Quantitative and qualitative deficiencies of regulatory T cells in patients with systemic lupus erythematosus (SLE).Q44098845
Androgenic status of males with systemic lupus erythematosusQ44156151
Evidence for the presence of androgen receptors in the synovial tissue of rheumatoid arthritis patients and healthy controlsQ44815684
Effects of prasterone on disease activity and symptoms in women with active systemic lupus erythematosusQ45081882
Development of systemic lupus erythematosus in a male-to-female transsexual: the role of sex hormones revisitedQ45721965
Effect of estrogen and progesterone on macrophage activation during wound healingQ46157697
Myeloid-derived suppressor cells contribute to systemic lupus erythaematosus by regulating differentiation of Th17 cells and TregsQ46541732
Elimination of Granulocytic Myeloid-Derived Suppressor Cells in Lupus-Prone Mice Linked to Reactive Oxygen Species-Dependent Extracellular Trap FormationQ46662797
Testosterone patches in the management of patients with mild/moderate systemic lupus erythematosusQ46780001
Effects of dehydroepiandrosterone supplement on health-related quality of life in glucocorticoid treated female patients with systemic lupus erythematosusQ46864446
Dihydrotestosterone levels at birth associate positively with higher proportions of circulating immature/naïve CD5+ B cells in boysQ46974888
Significant symptomatic improvement of subacute cutaneous lupus after testosterone therapy in a female-to-male transgender subjectQ47616038
IL-6 receptor blockage inhibits the onset of autoimmune kidney disease in NZB/W F1 miceQ47901598
Neutrophils Slow Disease Progression in Murine Lupus via Modulation of Autoreactive Germinal CentersQ48325825
Myeloid-Derived Suppressor Cells Induce the Expansion of Regulatory B Cells and Ameliorate Autoimmunity in the Sanroque Mouse Model of Systemic Lupus ErythematosusQ48955929
Gr-1(high) CD11b+ cells suppress B cell differentiation and lupus-like disease in lupus-prone male mice.Q50919779
Gr1+ cells suppress T-dependent antibody responses in (NZB x NZW)F1 male mice through inhibition of T follicular helper cells and germinal center formation.Q51167398
A double-blind, placebo-controlled, clinical trial of dehydroepiandrosterone in severe systemic lupus erythematosus.Q53931682
Treatment of systemic lupus erythematosus with dehydroepiandrosterone: 50 patients treated up to 12 months.Q53958684
Factors Influencing the Differentiation of Human Monocytic Myeloid-Derived Suppressor Cells Into Inflammatory Macrophages.Q55040962
Testosterone is an endogenous regulator of BAFF and splenic B cell number.Q55171520
Androgen-Induced Immunosuppression.Q55357541
Adoptive Regulatory T Cell Therapy in a Patient with Systemic Lupus ErythematosusQ57052192
Androgen and Androgen Receptor as Enhancers of M2 Macrophage Polarization in Allergic Lung InflammationQ57284683
Sex Hormones Determine Immune ResponseQ58700785
Novel Treatments in LupusQ59798146
Identification of alterations in macrophage activation associated with disease activity in systemic lupus erythematosusQ60301328
Phenotypic and Functional Diversities of Myeloid-Derived Suppressor Cells in Autoimmune DiseasesQ60935643
Loss of the androgen receptor suppresses intrarenal calcium oxalate crystals deposition via altering macrophage recruitment/M2 polarization with change of the miR-185-5p/CSF-1 signalsQ64069377
Regulating IRFs in IFN Driven DiseaseQ64102243
Suppressed androgen receptor expression promotes M2 macrophage reprogramming through the STAT3/SOCS3 pathwayQ64298437
Research Progress on Regulatory B Cells in Systemic Lupus Erythematosus.Q64996308
Increased CD14+HLA-DR-/low Myeloid-Derived Suppressor Cells Correlate With Disease Severity in Systemic Lupus Erythematosus Patients in an iNOS-Dependent Manner.Q64998120
Plasma sex hormones and aromatase activity in tissues of patients with systemic lupus erythematosusQ67482142
Experience with 19-nortestosterone in the therapy of systemic lupus erythematosus: worsened disease after treatment with 19-nortestosterone in men and lack of improvement in womenQ68136500
Sex hormones in male patients with systemic lupus erythematosus: a comparison with other disease groupsQ70510524
Castration alters peripheral immune function in normal male miceQ72238590
Plasma androgens in women with disseminated lupus erythematosusQ72780327
Alterations in peripheral B cells and B cell progenitors following androgen ablation in miceQ73702849
Testosterone suppresses anti-DNA antibody production in peripheral blood mononuclear cells from patients with systemic lupus erythematosusQ73766197
Profile of sex hormones in male patients with systemic lupus erythematosusQ73922586
New onset systemic lupus erythematosus in a transgender man: possible role of feminizing sex hormonesQ79721086
Dysfunctional CD4+,CD25+ regulatory T cells in untreated active systemic lupus erythematosus secondary to interferon-alpha-producing antigen-presenting cellsQ80800895
Macrophage Polarization Modulates Development of Systemic Lupus ErythematosusQ86363420
Regulatory T cells in autoimmune diseaseQ89171054
BAFF inhibition attenuates fibrosis in scleroderma by modulating the regulatory and effector B cell balanceQ90225269
Update on the epidemiology, risk factors, and disease outcomes of systemic lupus erythematosusQ90346707
B cell alterations during BAFF inhibition with belimumab in SLEQ90795990
PAM3 supports the generation of M2-like macrophages from lupus patient monocytes and improves disease outcome in murine lupusQ91208596
New-onset lupus nephritis after male-to-female sex reassignment surgeryQ91550342
Biologics in the Treatment of Lupus Erythematosus: A Critical Literature ReviewQ92513141
Therapeutic effects of a novel BAFF blocker on arthritisQ92972089
P275copyright licenseCreative Commons Attribution 4.0 InternationalQ20007257
P921main subjectanti-inflammatory agentQ581996
P304page(s)1271
P577publication date2020-06-23
P1433published inFrontiers in ImmunologyQ27723748
P1476titleAndrogen-Mediated Anti-inflammatory Cellular Processes as Therapeutic Targets in Lupus
P478volume11

Search more.