M2 macrophage-derived extracellular vesicles promote gastric cancer progression via a microRNA-130b-3p/MLL3/GRHL2 signaling cascade

scientific article published on 13 July 2020

M2 macrophage-derived extracellular vesicles promote gastric cancer progression via a microRNA-130b-3p/MLL3/GRHL2 signaling cascade is …
instance of (P31):
scholarly articleQ13442814
retracted paperQ45182324

External links are
P356DOI10.1186/S13046-020-01626-7
P932PMC publication ID7359233
P698PubMed publication ID32660626

P2093author name stringYu Zhang
Ping Yue
Xun Li
Wenbo Meng
P2860cites workDiagnosis and management of high risk group for gastric cancerQ28084323
Tumor-associated macrophages of the M2 phenotype contribute to progression in gastric cancer with peritoneal dissemination.Q30372640
Exosomal transfer of tumor-associated macrophage-derived miR-21 confers cisplatin resistance in gastric cancer cellsQ33560646
MLL3/MLL4 are required for CBP/p300 binding on enhancers and super-enhancer formation in brown adipogenesisQ33878669
MicroRNA profiling of human gastric cancerQ34176847
Current issues and future perspectives of gastric cancer screeningQ34326609
Exosome-mediated transfer of microRNAs within the tumor microenvironment and neuroblastoma resistance to chemotherapyQ36294761
The miR-130 family promotes cell migration and invasion in bladder cancer through FAK and Akt phosphorylation by regulating PTEN.Q36536455
Exosomes derived from HCC cells induce sorafenib resistance in hepatocellular carcinoma both in vivo and in vitroQ37302281
Exosomes play an important role in the process of psoralen reverse multidrug resistance of breast cancerQ37460734
Onco-miR-130 promotes cell proliferation and migration by targeting TGFβR2 in gastric cancerQ37536942
Tumor-recruited M2 macrophages promote gastric and breast cancer metastasis via M2 macrophage-secreted CHI3L1 proteinQ37618668
Grhl2 reduces invasion and migration through inhibition of TGFβ-induced EMT in gastric cancerQ37627432
Interleukin 6 induces M2 macrophage differentiation by STAT3 activation that correlates with gastric cancer progressionQ38614760
MET-targeted therapy for gastric cancer: the importance of a biomarker-based strategy.Q38675350
Gastric cancer: somatic genetics as a guide to therapyQ38823161
Expression and role of grainyhead-like 2 in gastric cancerQ39091704
The influence of socioeconomic status on gestational weight gain: a systematic reviewQ39234319
The role of miR-130a in cancerQ39287026
MicroRNA-130b regulates the tumour suppressor RUNX3 in gastric cancerQ39736530
Exosomes mediate the cell-to-cell transmission of IFN-α-induced antiviral activityQ42285504
Prognostic implications for high expression of oncogenic microRNAs in advanced gastric carcinoma.Q44434844
KDM3A inhibition attenuates high concentration insulin‑induced vascular smooth muscle cell injury by suppressing MAPK/NF‑κB pathwaysQ47246628
Molecular mechanisms and theranostic potential of miRNAs in drug resistance of gastric cancerQ47673159
Tumor-derived exosomal miR-1247-3p induces cancer-associated fibroblast activation to foster lung metastasis of liver cancerQ49509990
Single molecule translocation in smectics illustrates the challenge for time-mapping in simulations on multiple scalesQ49919266
The application of nanoparticles in diagnosis and theranostics of gastric cancer.Q52962749
MicroRNA-363-mediated downregulation of S1PR1 suppresses the proliferation of hepatocellular carcinoma cells.Q54368464
Tumor-derived exosomes induce PD1+ macrophage population in human gastric cancer that promotes disease progression.Q54986381
Tumor-associated macrophages-derived exosomes promote the migration of gastric cancer cells by transfer of functional Apolipoprotein E.Q55282407
Resetting the epigenetic balance of Polycomb and COMPASS function at enhancers for cancer therapyQ56603206
Tumor-derived exosomes induce N2 polarization of neutrophils to promote gastric cancer cell migrationQ57183696
MLL3 enhances the transcription of PD-L1 and regulates anti-tumor immunityQ58596166
M2 macrophage-derived exosomes promote cell migration and invasion in colon cancerQ58605940
Exosomes in gastric cancer: roles, mechanisms, and applicationsQ64089055
microRNA-328 in exosomes derived from M2 macrophages exerts a promotive effect on the progression of pulmonary fibrosis via FAM13A in a rat model.Q64938035
Hypoxic Tumor-Derived Exosomal miR-301a Mediates M2 Macrophage Polarization via PTEN/PI3Kγ to Promote Pancreatic Cancer MetastasisQ89030115
Gastric cancer-derived mesenchymal stromal cells trigger M2 macrophage polarization that promotes metastasis and EMT in gastric cancerQ91697983
P433issue1
P921main subjectextracellular vesicleQ21097485
P304page(s)134
P577publication date2020-07-13
P1433published inJournal of Experimental & Clinical Cancer ResearchQ13739415
P1476titleM2 macrophage-derived extracellular vesicles promote gastric cancer progression via a microRNA-130b-3p/MLL3/GRHL2 signaling cascade
P478volume39

Reverse relations

cites work (P2860)
Q112637035A positive feedback loop between gastric cancer cells and tumor-associated macrophage induces malignancy progression
Q112613791CMPK1 Regulated by miR-130b Attenuates Response to 5-FU Treatment in Gastric Cancer
Q112292431Identification of Key Circulating Exosomal microRNAs in Gastric Cancer
Q112614334Identification of Stemness Characteristics Associated With the Immune Microenvironment and Prognosis in Gastric Cancer
Q112636809Transfer of microRNA-22-3p by M2 macrophage-derived extracellular vesicles facilitates the development of ankylosing spondylitis through the PER2-mediated Wnt/β-catenin axis
Q112647073microRNA-130b-3p Contained in MSC-Derived EVs Promotes Lung Cancer Progression by Regulating the FOXO3/NFE2L2/TXNRD1 Axis

Search more.