GWAS of thyroid stimulating hormone highlights pleiotropic effects and inverse association with thyroid cancer

scientific article published on 07 August 2020

GWAS of thyroid stimulating hormone highlights pleiotropic effects and inverse association with thyroid cancer is …
instance of (P31):
scholarly articleQ13442814

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P819ADS bibcode2020NatCo..11.3981Z
P356DOI10.1038/S41467-020-17718-Z
P932PMC publication ID7414135
P698PubMed publication ID32769997

P50authorAlbert de la ChapelleQ5618748
Kári StefánssonQ6453246
Michael BoehnkeQ6828710
George Davey SmithQ21003878
Juha KarjalainenQ23039806
Alexander TeumerQ28039340
Serena SannaQ28050036
Ida SurakkaQ29839641
Silvia NaitzaQ32985018
Cristen J. WillerQ37389746
Matthew ZawistowskiQ63719030
Cintia E CitterioQ86623465
Anne CappolaQ88050382
Sarah E GrahamQ89112636
Joshua WeinstockQ89768656
Romana T Netea-MaierQ89912308
Wei ZhouQ91290466
Ben BrumptonQ92602624
Morgan D OnekaQ93094534
Humaira RasheedQ98245651
Matthew D RingelQ98304510
Julius GudmundssonQ114530409
Hannes HjartarsonQ117262592
Jon HrafnkelssonQ117262593
Mark Joseph DalyQ39071290
Lambertus KiemeneyQ40024880
Bjørn Olav ÅsvoldQ41607561
Sandya LiyanarachchiQ43376214
Lars G FritscheQ47452535
Theo S PlantingaQ47503044
Jonas B NielsenQ56952461
Brooke N WolfordQ57165299
Erich M SturgisQ61112847
Leigha SenterQ63370944
P2093author name stringPeter Taylor
Omer Kabil
Li Xu
Marco Medici
Jon G Jonasson
Jose I Mayordomo
Tanmoy Roychowdhury
Aarno Palotie
Layal Chaker
Chad M Brummett
Kristian Hveem
Gudmar Thorleifsson
Mitja Kurki
Peter Arvan
Maiken E Gabrielsen
Huiling He
Whitney E Hornsby
Anita Pandit
Anne Heidi Skogholt
Eirin B Haug
Ulla T Schultheiss
William Overton
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Conditional and joint multiple-SNP analysis of GWAS summary statistics identifies additional variants influencing complex traitsQ36670925
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Thyroid-Stimulating Hormone, Thyroid Hormones, and Risk of Papillary Thyroid Cancer: A Nested Case-Control Study.Q40257921
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Frequent TSH receptor genetic alterations with variable signaling impairment in a large series of children with nonautoimmune isolated hyperthyrotropinemia.Q44574146
Serum thyrotropin concentration as a biochemical predictor of thyroid malignancy in patients presenting with thyroid nodules.Q46713092
TSH, Thyroid Hormone, and PTC-LetterQ50066610
Thermogenesis by THADA.Q50444806
The relationship between TSH and free T₄ in a large population is complex and nonlinear and differs by age and sex.Q51218122
Thyroid cancer mortality and incidence: a global overview.Q51260483
Thyroid-stimulating hormone, thyroglobulin, and thyroid hormones and risk of differentiated thyroid carcinoma: the EPIC study.Q51322666
Detection of widespread horizontal pleiotropy in causal relationships inferred from Mendelian randomization between complex traits and diseases.Q52311755
Role of Human Leukocyte Antigens (HLA) in Autoimmune Diseases.Q52727983
The MR-Base platform supports systematic causal inference across the human phenome.Q55427190
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The UK Biobank resource with deep phenotyping and genomic dataQ57296608
Association of Polygenic Risk Scores for Multiple Cancers in a Phenome-wide Study: Results from The Michigan Genomics InitiativeQ57612089
Genome-wide analyses identify a role for SLC17A4 and AADAT in thyroid hormone regulationQ58061656
THADA Regulates the Organismal Balance between Energy Storage and Heat ProductionQ58374814
P433issue1
P921main subjectthyroid cancerQ826522
genome-wide association studyQ1098876
pleiotropyQ1134884
P304page(s)3981
P577publication date2020-08-07
P1433published inNature CommunicationsQ573880
P1476titleGWAS of thyroid stimulating hormone highlights pleiotropic effects and inverse association with thyroid cancer
P478volume11

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