β-catenin and γ-catenin are dispensable for T lymphocytes and AML leukemic stem cells

scientific article published on 21 August 2020

β-catenin and γ-catenin are dispensable for T lymphocytes and AML leukemic stem cells is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.7554/ELIFE.55360
P932PMC publication ID7462606
P698PubMed publication ID32820720

P50authorHai-Hui XueQ55313234
P2093author name stringXin Zhao
Qiang Shan
Peng Shao
Fengyin Li
Kexin Gai
P2860cites workWnt signaling arrests effector T cell differentiation and generates CD8+ memory stem cellsQ24651232
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Requirement for beta-catenin in anterior-posterior axis formation in miceQ28507627
Redundant regulation of T cell differentiation and TCRalpha gene expression by the transcription factors LEF-1 and TCF-1Q28513432
Deletion of β-catenin impairs T cell developmentQ28587501
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TCF-1 and LEF-1 act upstream of Th-POK to promote the CD4(+) T cell fate and interact with Runx3 to silence Cd4 in CD8(+) T cellsQ33779910
Essential role of the Wnt pathway effector Tcf-1 for the establishment of functional CD8 T cell memory.Q34006736
Differentiation and persistence of memory CD8(+) T cells depend on T cell factor 1Q34085034
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LEF-1 and TCF-1 orchestrate T(FH) differentiation by regulating differentiation circuits upstream of the transcriptional repressor Bcl6Q35983849
TCF1 Is Required for the T Follicular Helper Cell Response to Viral Infection.Q36113729
Effects of forced expression of an NH2-terminal truncated beta-Catenin on mouse intestinal epithelial homeostasisQ36255369
Beta-catenin is dispensable for hematopoiesis and lymphopoiesisQ36399011
Loss of beta-catenin impairs the renewal of normal and CML stem cells in vivoQ36488720
Hematopoietic and Leukemic Stem Cells Have Distinct Dependence on Tcf1 and Lef1 Transcription Factors.Q36987654
WNT signalling in the immune system: WNT is spreading its wingsQ37212748
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Influence of time and number of antigen encounters on memory CD8 T cell development.Q38211624
From inception to output, Tcf1 and Lef1 safeguard development of T cells and innate immune cells.Q38213433
T follicular helper cell differentiation, function, and roles in diseaseQ38264816
Translocation products in acute myeloid leukemia activate the Wnt signaling pathway in hematopoietic cells.Q38343552
Differential Requirements for Tcf1 Long Isoforms in CD8+ and CD4+ T Cell Responses to Acute Viral Infection.Q38708013
Cutting Edge: β-Catenin-Interacting Tcf1 Isoforms Are Essential for Thymocyte Survival but Dispensable for Thymic Maturation Transitions.Q38872732
Motor neuron position and topographic order imposed by β- and γ-catenin activitiesQ39464378
β-Catenin mediates the establishment and drug resistance of MLL leukemic stem cellsQ39620290
The transcription factor TCF-1 initiates the differentiation of T(FH) cells during acute viral infection.Q41088363
The TCF-1 and LEF-1 transcription factors have cooperative and opposing roles in T cell development and malignancy.Q41510704
Hematopoietic stem cell development requires transient Wnt/β-catenin activityQ41814485
Constitutive activation of Wnt signaling favors generation of memory CD8 T cellsQ41830072
Beta-catenin stabilization stalls the transition from double-positive to single-positive stage and predisposes thymocytes to malignant transformationQ41869389
Cutting edge: β-catenin is dispensable for T cell effector differentiation, memory formation, and recall responses.Q41886494
Targeting tetramer-forming GABPβ isoforms impairs self-renewal of hematopoietic and leukemic stem cells.Q42038343
A C-terminally truncated form of β-catenin acts as a novel regulator of Wnt/β-catenin signaling in planarians.Q42695832
The Wnt/beta-catenin pathway is required for the development of leukemia stem cells in AML.Q42723875
beta-Catenin is essential for survival of leukemic stem cells insensitive to kinase inhibition in mice with BCR-ABL-induced chronic myeloid leukemiaQ46345796
The transcription factor Runx3 guards cytotoxic CD8+ effector T cells against deviation towards follicular helper T cell lineage.Q47149143
Disruption of peripheral leptin signaling in mice results in hyperleptinemia without associated metabolic abnormalitiesQ48171683
Tcf7l1 protects the anterior neural fold from adopting the neural crest fate.Q48200084
Stabilization of NF-κB-Inducing Kinase Suppresses MLL-AF9-Induced Acute Myeloid LeukemiaQ49216080
Activation of the canonical Wnt pathway leads to loss of hematopoietic stem cell repopulation and multilineage differentiation block.Q50926584
Beta-catenin does not regulate memory T cell phenotype.Q51054671
Prostaglandin E1 and Its Analog Misoprostol Inhibit Human CML Stem Cell Self-Renewal via EP4 Receptor Activation and Repression of AP-1.Q52757771
Hematopoietic stem cell and multilineage defects generated by constitutive β-catenin activationQ57615464
An HMG-box-containing T-cell factor required for thymocyte differentiation.Q59058515
Functional genomic landscape of acute myeloid leukaemiaQ59086861
Ezh2 programs T differentiation by integrating phosphorylation-dependent activation of Bcl6 and polycomb-dependent repression of p19ArfQ60300338
The beta-catenin--TCF-1 pathway ensures CD4(+)CD8(+) thymocyte survivalQ74286666
Beta-catenin stabilization extends regulatory T cell survival and induces anergy in nonregulatory T cellsQ80622205
Simultaneous loss of beta- and gamma-catenin does not perturb hematopoiesis or lymphopoiesisQ81250982
Long-term, multilineage hematopoiesis occurs in the combined absence of beta-catenin and gamma-cateninQ81375017
Stabilized beta-catenin extends thymocyte survival by up-regulating Bcl-xLQ81598302
Control of Lymphocyte Fate, Infection, and Tumor Immunity by TCF-1Q91307277
Cutting Edge: Tcf1 Instructs T Follicular Helper Cell Differentiation by Repressing Blimp1 in Response to Acute Viral InfectionQ91839392
P577publication date2020-08-21
P1433published ineLifeQ2000008
P1476titleβ-catenin and γ-catenin are dispensable for T lymphocytes and AML leukemic stem cells
P478volume9

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