RINT1 Loss Impairs Retinogenesis Through TRP53-Mediated Apoptosis

scientific article published on 30 July 2020

RINT1 Loss Impairs Retinogenesis Through TRP53-Mediated Apoptosis is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.3389/FCELL.2020.00711
P932PMC publication ID7406574
P698PubMed publication ID32850831

P2093author name stringPierre-Olivier Frappart
Anielle L Gomes
Gabriel E Matos-Rodrigues
Rodrigo A P Martins
P2860cites workRINT-1, a novel Rad50-interacting protein, participates in radiation-induced G(2)/M checkpoint controlQ24290563
RINT-1 regulates the localization and entry of ZW10 to the syntaxin 18 complexQ24311852
Implication of ZW10 in membrane trafficking between the endoplasmic reticulum and GolgiQ24317648
Chk1 is an essential kinase that is regulated by Atr and required for the G(2)/M DNA damage checkpointQ24604730
The DNA-damage response in human biology and diseaseQ24606586
Classification of cell death: recommendations of the Nomenclature Committee on Cell Death 2009Q24653924
RINT-1 serves as a tumor suppressor and maintains Golgi dynamics and centrosome integrity for cell survivalQ24675915
Moonlighting functions of the NRZ (mammalian Dsl1) complexQ26825961
Math5 is required for retinal ganglion cell and optic nerve formationQ28345639
Requirement for math5 in the development of retinal ganglion cellsQ28345916
Math5 determines the competence state of retinal ganglion cell progenitorsQ28506349
An essential function for NBS1 in the prevention of ataxia and cerebellar defectsQ28507300
Defective neurogenesis resulting from DNA ligase IV deficiency requires AtmQ28510231
Ocular Anomalies in Seckel's SyndromeQ69040073
A P53-Independent DNA Damage Response Suppresses Oncogenic Proliferation and Genome InstabilityQ89548697
The Role of Autophagy in Glaucomatous Optic NeuropathyQ90643285
An intrinsic S/G2 checkpoint enforced by ATRQ91113594
DNA double-strand break repair-pathway choice in somatic mammalian cellsQ91529889
RAG-2 deficiency results in fewer phosphorylated histone H2AX foci, but increased retinal ganglion cell death and altered axonal growthQ91767877
The multiple mechanisms that regulate p53 activity and cell fateQ92062954
De novo genesis of retinal ganglion cells by targeted expression of Klf4 in vivoQ92576583
Neurogenesis and Specification of Retinal Ganglion CellsQ92637310
RINT1 Bi-allelic Variations Cause Infantile-Onset Recurrent Acute Liver Failure and Skeletal AbnormalitiesQ92780373
Aneuploid acute myeloid leukemia exhibits a signature of genomic alterations in the cell cycle and protein degradation machineryQ93336562
Conditional inactivation of the NBS1 gene in the mouse central nervous system leads to neurodegeneration and disorganization of the visual systemQ41938037
Bloom syndrome: multiple retinopathies in a chromosome breakage disorderQ42219871
DNA-PK promotes the survival of young neurons in the embryonic mouse retinaQ43071286
Retinal Features in Seckel's SyndromeQ44618676
Radiation-induced apoptosis in developing mouse retina exhibits dose-dependent requirement for ATM phosphorylation of p53.Q44749119
Timing and topography of cell genesis in the rat retinaQ44911589
Cell differentiation in the retina of the mouseQ45193462
Congenital hypertrophy of retinal pigment epithelium in non-Gardner's polyposis kindredsQ45879873
Genome integrity and disease prevention in the nervous systemQ47148140
Characterization of the phenotype and birthdates of pyknotic dead cells in the nervous system by a combination of DNA staining and immunohistochemistry for 5'-bromodeoxyuridine and neural antigensQ48277761
The early development of the optic nerve and chiasm in embryonic rat.Q48385159
Synergistic tumor suppressor activity of BRCA2 and p53 in a conditional mouse model for breast cancer.Q52544495
Bilateral retinal detachment in Seckel syndrome.Q52873379
BRCA2 function and the central nervous system.Q53530318
The MRE11-RAD50-NBS1 Complex Conducts the Orchestration of Damage Signaling and Outcomes to Stress in DNA Replication and Repair.Q54980026
Identification of candidate cancer predisposing variants by performing whole-exome sequencing on index patients from BRCA1 and BRCA2-negative breast cancer familiesQ64075131
The intersection between DNA damage response and cell death pathwaysQ28611423
Rare mutations in RINT1 predispose carriers to breast and Lynch syndrome-spectrum cancersQ28652056
qBase relative quantification framework and software for management and automated analysis of real-time quantitative PCR dataQ29616810
The intersection of Golgi-ER retrograde and autophagic traffickingQ33357109
Retinal vasculopathy in Fanconi anemiaQ33505745
A p53-independent role for the MDM2 antagonist Nutlin-3 in DNA damage response initiationQ33825730
The MRN complex in double-strand break repair and telomere maintenanceQ34127693
Regulating proliferation during retinal developmentQ34238084
The p53 network: cellular and systemic DNA damage responses in aging and cancerQ34248711
Requirement for Atm in ionizing radiation-induced cell death in the developing central nervous systemQ34467644
The Rb-related p130 protein controls telomere lengthening through an interaction with a Rad50-interacting protein, RINT-1.Q34511522
Nbn and atm cooperate in a tissue and developmental stage-specific manner to prevent double strand breaks and apoptosis in developing brain and eye.Q34919494
From progenitors to differentiated cells in the vertebrate retinaQ34990515
Neurogenesis and the Cell CycleQ35558404
Morphological features of cell deathQ35773151
Math5 defines the ganglion cell competence state in a subpopulation of retinal progenitor cells exiting the cell cycle.Q35914616
Cell Cycle Regulation and Apoptotic Responses of the Embryonic Chick Retina by Ionizing RadiationQ36013224
Evaluation of Rint1 as a modifier of intestinal tumorigenesis and cancer riskQ36298287
Integrative functional genomics identifies RINT1 as a novel GBM oncogeneQ36344771
Developmental abnormalities of the optic nerve and chiasmQ36959882
Mouse models of DNA double-strand break repair and neurological diseaseQ37155146
A new role for RINT-1 in SNARE complex assembly at the trans-Golgi network in coordination with the COG complexQ37167924
The p53 family and programmed cell deathQ37310208
Rint1 inactivation triggers genomic instability, ER stress and autophagy inhibition in the brain.Q37354009
The molecular basis of retinal ganglion cell death in glaucomaQ37966513
Retinal neurogenesisQ38175009
Bilateral retinal detachment in Werner syndromeQ38265224
The essential kinase ATR: ensuring faithful duplication of a challenging genome.Q38622938
N-myc regulates growth and fiber cell differentiation in lens developmentQ38674970
RINT-1 interacts with MSP58 within nucleoli and plays a role in ribosomal gene transcriptionQ38751504
Autophagy in the eye: Development, degeneration, and agingQ38938383
A role for the MRN complex in ATR activation via TOPBP1 recruitmentQ39167332
ATR maintains chromosomal integrity during postnatal cerebellar neurogenesis and is required for medulloblastoma formationQ39226312
Pax6 is required for the multipotent state of retinal progenitor cellsQ40813005
Birth dates of retinal ganglion cells giving rise to the crossed and uncrossed optic projections in the mouseQ41387837
ATR maintains select progenitors during nervous system developmentQ41767755
Neurogenesis requires TopBP1 to prevent catastrophic replicative DNA damage in early progenitors.Q41826040
P275copyright licenseCreative Commons Attribution 4.0 InternationalQ20007257
P6216copyright statuscopyrightedQ50423863
P304page(s)711
P577publication date2020-07-30
P1433published inFrontiers in Cell and Developmental BiologyQ27725488
P1476titleRINT1 Loss Impairs Retinogenesis Through TRP53-Mediated Apoptosis
P478volume8

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