| P2093 | author name string | Alice L Rodriguez | |
| | Colleen M Niswender | |
| | Craig W Lindsley | |
| | P Jeffrey Conn | |
| | Anna L Blobaum | |
| | Carson W Reed | |
| | Jordan P Washecheck | |
| | Ashton Hunter | |
| | Jacob J Kalbfleisch | |
| | Madison J Wong | |
| P2860 | cites work | The metabotropic glutamate receptor subtype 7 rs3792452 polymorphism is associated with the response to methylphenidate in children with attention-deficit/hyperactivity disorder. | Q53281893 |
| | Metabotropic Glutamate Receptor 7: A New Therapeutic Target in Neurodevelopmental Disorders | Q58573091 |
| | VU6010608, a Novel mGlu7 NAM from a Series of N-(2-(1H-1,2,4-Triazol-1-yl)-5-(trifluoromethoxy)phenyl)benzamides | Q89689611 |
| | Discovery of an Orally Bioavailable and Central Nervous System (CNS) Penetrant mGlu7 Negative Allosteric Modulator (NAM) in Vivo Tool Compound: N-(2-(1 H-1,2,4-triazol-1-yl)-5-(trifluoromethoxy)phenyl)-4-(cyclopropylmethoxy)-3-methoxybenzamide (VU60 | Q90878633 |
| | Surveying heterocycles as amide bioisosteres within a series of mGlu7 NAMs: Discovery of VU6019278 | Q92610895 |
| | Synthesis and SAR of a series of mGlu7 NAMs based on an ethyl-8-methoxy-4-(4-phenylpiperazin-1-yl)quinoline carboxylate core | Q99200520 |
| | Phasic and Tonic mGlu7 Receptor Activity Modulates the Thalamocortical Network | Q27318820 |
| | Genome-wide copy number variation study associates metabotropic glutamate receptor gene networks with attention deficit hyperactivity disorder | Q28254567 |
| | Increased seizure susceptibility in mice lacking metabotropic glutamate receptor 7 | Q28507609 |
| | Concomitant deficits in working memory and fear extinction are functionally dissociated from reduced anxiety in metabotropic glutamate receptor 7-deficient mice | Q28508341 |
| | Lack of the metabotropic glutamate receptor subtype 7 selectively modulates Theta rhythm and working memory | Q28513068 |
| | Lack of the metabotropic glutamate receptor subtype 7 selectively impairs short-term working memory but not long-term memory | Q28589028 |
| | Metabotropic glutamate receptor subtype 7 ablation causes deficit in fear response and conditioned taste aversion | Q28594987 |
| | Novel loci for major depression identified by genome-wide association study of Sequenced Treatment Alternatives to Relieve Depression and meta-analysis of three studies | Q28751388 |
| | Identification of positive allosteric modulators VU0155094 (ML397) and VU0422288 (ML396) reveals new insights into the biology of metabotropic glutamate receptor 7 | Q30402875 |
| | A family-based association study of DNA sequence variants in GRM7 with schizophrenia in an Indonesian population | Q33488127 |
| | Characterization of the novel positive allosteric modulator of the metabotropic glutamate receptor 4 ADX88178 in rodent models of neuropsychiatric disorders | Q34125116 |
| | A selective metabotropic glutamate receptor 7 agonist: activation of receptor signaling via an allosteric site modulates stress parameters in vivo | Q34234693 |
| | ADX71743, a potent and selective negative allosteric modulator of metabotropic glutamate receptor 7: in vitro and in vivo characterization | Q34318862 |
| | Allelic association, DNA resequencing and copy number variation at the metabotropic glutamate receptor GRM7 gene locus in bipolar disorder | Q34507224 |
| | Association between the GRM7 rs3792452 polymorphism and attention deficit hyperacitiveity disorder in a Korean sample | Q34538304 |
| | Activation of the mGlu7 receptor elicits antidepressant-like effects in mice | Q34648343 |
| | Exome sequencing in mostly consanguineous Arab families with neurologic disease provides a high potential molecular diagnosis rate | Q36082177 |
| | Practical Strategies and Concepts in GPCR Allosteric Modulator Discovery: Recent Advances with Metabotropic Glutamate Receptors | Q37183072 |
| | Metabotropic glutamate receptors: physiology, pharmacology, and disease | Q37670222 |
| | Rare de novo deletion of metabotropic glutamate receptor 7 (GRM7) gene in a patient with autism spectrum disorder | Q38447329 |
| | Diagnostic Yield and Novel Candidate Genes by Exome Sequencing in 152 Consanguineous Families With Neurodevelopmental Disorders. | Q39015715 |
| | Genome-wide association study of response to methylphenidate in 187 children with attention-deficit/hyperactivity disorder | Q42598732 |
| | A genome-wide significant linkage for severe depression on chromosome 3: the depression network study | Q43756830 |
| | The metabotropic glutamate receptor 7 allosteric modulator AMN082: a monoaminergic agent in disguise? | Q44369820 |
| | Deficits in acquisition and extinction of conditioned responses in mGluR7 knockout mice | Q46741586 |
| | Metabotropic glutamate receptor subtype 7 ablation causes dysregulation of the HPA axis and increases hippocampal BDNF protein levels: implications for stress-related psychiatric disorders | Q46764278 |
| | mGlu7 potentiation rescues cognitive, social, and respiratory phenotypes in a mouse model of Rett syndrome. | Q47738098 |
| | High-resolution chromosome ideogram representation of recognized genes for bipolar disorder. | Q48058600 |
| | Significant association of GRM7 and GRM8 genes with schizophrenia and major depressive disorder in the Han Chinese population | Q48068852 |
| | Discovery of VU6005649, a CNS Penetrant mGlu7/8 Receptor PAM Derived from a Series of Pyrazolo[1,5-a]pyrimidines | Q50066117 |
| | Role of metabotropic glutamate receptor 7 in autism spectrum disorders: a pilot study | Q50303624 |
| | Altered short-term synaptic plasticity in mice lacking the metabotropic glutamate receptor mGlu7. | Q52007247 |
| P433 | issue | 9 | |
| P304 | page(s) | 1773-1779 | |
| P577 | publication date | 2020-08-20 | |
| P1433 | published in | ACS Medicinal Chemistry Letters | Q2819061 |
| P1476 | title | Discovery of VU6027459: A First-in-Class Selective and CNS Penetrant mGlu7 Positive Allosteric Modulator Tool Compound | |
| P478 | volume | 11 | |