| scholarly article | Q13442814 |
| P356 | DOI | 10.1038/S41598-020-73249-Z |
| P698 | PubMed publication ID | 33004905 |
| P2093 | author name string | Sandra Nuyts | |
| Mary Glorieux | |||
| Rüveyda Dok | |||
| P2860 | cites work | Identification and Characterization of NVP-BKM120, an Orally Available Pan-Class I PI3-Kinase Inhibitor | Q27676347 |
| Frequent mutation of the PI3K pathway in head and neck cancer defines predictive biomarkers | Q27852227 | ||
| Response of head and neck squamous cell carcinoma cells carrying PIK3CA mutations to selected targeted therapies | Q27853149 | ||
| PI3K mutations in breast cancer: prognostic and therapeutic implications | Q28081992 | ||
| Comprehensive genomic characterization of head and neck squamous cell carcinomas | Q28256121 | ||
| PI3K and cancer: lessons, challenges and opportunities | Q30080017 | ||
| Deconvolution of Buparlisib's mechanism of action defines specific PI3K and tubulin inhibitors for therapeutic intervention | Q30841629 | ||
| Inhibition of phosphatidylinositol 3-kinase/AKT signaling by NVP-BKM120 promotes ABT-737-induced toxicity in a caspase-dependent manner through mitochondrial dysfunction and DNA damage response in established and primary cultured glioblastoma cells | Q33750838 | ||
| Targeting Phosphatidylinositide3-Kinase/Akt pathway by BKM120 for radiosensitization in hepatocellular carcinoma | Q33977001 | ||
| Interaction of radiation therapy with molecular targeted agents | Q34124285 | ||
| PIK3CA mutations in androgen receptor-positive triple negative breast cancer confer sensitivity to the combination of PI3K and androgen receptor inhibitors | Q34296476 | ||
| A genetic basis for the variation in the vulnerability of cancer to DNA damage | Q34523304 | ||
| Radiation Enhancement of Head and Neck Squamous Cell Carcinoma by the Dual PI3K/mTOR Inhibitor PF-05212384. | Q35751948 | ||
| Role of Phosphatidylinositol-3-Kinase Pathway in Head and Neck Squamous Cell Carcinoma | Q35994228 | ||
| Dual Targeting of Akt and mTORC1 Impairs Repair of DNA Double-Strand Breaks and Increases Radiation Sensitivity of Human Tumor Cells | Q36006229 | ||
| Buparlisib and paclitaxel in patients with platinum-pretreated recurrent or metastatic squamous cell carcinoma of the head and neck (BERIL-1): a randomised, double-blind, placebo-controlled phase 2 trial | Q36263259 | ||
| DNA double strand break repair defect and sensitivity to poly ADP-ribose polymerase (PARP) inhibition in human papillomavirus 16-positive head and neck squamous cell carcinoma | Q36413681 | ||
| Defining biomarkers to predict sensitivity to PI3K/Akt/mTOR pathway inhibitors in breast cancer | Q36703783 | ||
| PI3K/mTOR Inhibitor PF-04691502 Antitumor Activity Is Enhanced with Induction of Wild-Type TP53 in Human Xenograft and Murine Knockout Models of Head and Neck Cancer | Q37025086 | ||
| Activation of the PI3-K/AKT pathway and implications for radioresistance mechanisms in head and neck cancer | Q37097424 | ||
| Antitumor Activity of NVP-BKM120—A Selective Pan Class I PI3 Kinase Inhibitor Showed Differential Forms of Cell Death Based on p53 Status of Glioma Cells | Q37203000 | ||
| PI3 Kinase Pathway and MET Inhibition is Efficacious in Malignant Pleural Mesothelioma | Q37252398 | ||
| The phosphatidylinositol‐3 kinase I inhibitor BKM120 induces cell death in B‐chronic lymphocytic leukemia cells in vitro | Q37358321 | ||
| Integrative radiogenomic profiling of squamous cell lung cancer | Q37375987 | ||
| Nuclear p16INK4a expression predicts enhanced radiation response in head and neck cancers | Q37437660 | ||
| COSMIC: somatic cancer genetics at high-resolution | Q37556877 | ||
| Doubling down on the PI3K-AKT-mTOR pathway enhances the antitumor efficacy of PARP inhibitor in triple negative breast cancer model beyond BRCA-ness | Q37584321 | ||
| The ATP-competitive mTOR inhibitor INK128 enhances in vitro and in vivo radiosensitivity of pancreatic carcinoma cells | Q37626177 | ||
| Phosphatidylinositide 3-kinase (PI3K) and PI3K-related kinase (PIKK) activity contributes to radioresistance in thyroid carcinomas | Q37665265 | ||
| Blockade efficacy of MEK/ERK-dependent autophagy enhances PI3K/Akt inhibitor NVP-BKM120's therapeutic effectiveness in lung cancer cells | Q37687154 | ||
| The hedgehog inhibitor GANT61 sensitizes prostate cancer cells to ionizing radiation both in vitro and in vivo | Q37708945 | ||
| PI3K and Akt as molecular targets for cancer therapy: current clinical outcomes | Q37727180 | ||
| Novel method for PIK3CA mutation analysis: locked nucleic acid--PCR sequencing | Q38094416 | ||
| Targeting PI3K in Cancer: Any Good News? | Q38105322 | ||
| Radioresistance in head and neck squamous cell carcinoma: Biological bases and therapeutic implications | Q38226307 | ||
| Targeting the PI3K/AKT/mTOR pathway in squamous cell carcinoma of the head and neck | Q38297381 | ||
| Targeting EGFR-PI3K-AKT-mTOR signaling enhances radiosensitivity in head and neck squamous cell carcinoma | Q38344592 | ||
| Phosphatidylinositol 3-kinase/Akt signaling as a key mediator of tumor cell responsiveness to radiation | Q38550785 | ||
| Inhibiting the PI3K signaling pathway: buparlisib as a new targeted option in breast carcinoma | Q38618654 | ||
| In Vitro and In Vivo Synergistic Antitumor Activity of the Combination of BKM120 and Erlotinib in Head and Neck Cancer: Mechanism of Apoptosis and Resistance | Q38719583 | ||
| Treatment effect of buparlisib, cetuximab and irradiation in wild-type or PI3KCA-mutated head and neck cancer cell lines | Q38918345 | ||
| In vitro multifaceted activities of a specific group of novel phosphatidylinositol 3-kinase inhibitors on hotspot mutant PIK3CA. | Q38963261 | ||
| Increased radiosensitivity of HPV-positive head and neck cancer cell lines due to cell cycle dysregulation and induction of apoptosis | Q39006076 | ||
| Regulation of O2 consumption by the PI3K and mTOR pathways contributes to tumor hypoxia | Q39015424 | ||
| p16INK4a impairs homologous recombination-mediated DNA repair in human papillomavirus-positive head and neck tumors. | Q39029551 | ||
| HNSCC cell lines positive for HPV and p16 possess higher cellular radiosensitivity due to an impaired DSB repair capacity | Q39163509 | ||
| Characterization of the Mechanism of Action of the Pan Class I PI3K Inhibitor NVP-BKM120 across a Broad Range of Concentrations | Q39338784 | ||
| Inhibitor of pan class-I PI3K induces differentially apoptotic pathways in acute leukemia cells: Shedding new light on NVP-BKM120 mechanism of action. | Q39418236 | ||
| GDC-0980 is a novel class I PI3K/mTOR kinase inhibitor with robust activity in cancer models driven by the PI3K pathway | Q39458307 | ||
| Head and neck cancer: improving outcomes with a multidisciplinary approach. | Q41522410 | ||
| Misregulation of DNA damage repair pathways in HPV-positive head and neck squamous cell carcinoma contributes to cellular radiosensitivity | Q42244844 | ||
| Preclinical Assessment of the Absorption and Disposition of the Phosphatidylinositol 3-Kinase/Mammalian Target of Rapamycin Inhibitor GDC-0980 and Prediction of Its Pharmacokinetics and Efficacy in Human | Q42717476 | ||
| Selective PI3K inhibition by BKM120 and BEZ235 alone or in combination with chemotherapy in wild-type and mutated human gastrointestinal cancer cell lines | Q43411752 | ||
| Novel DNA targeted therapies for head and neck cancers: clinical potential and biomarkers | Q45790068 | ||
| Akt1 Stimulates Homologous Recombination Repair of DNA Double-Strand Breaks in a Rad51-Dependent Manner | Q47383621 | ||
| Hsp90 inhibition enhances PI-3 kinase inhibition and radiosensitivity in glioblastoma. | Q51754497 | ||
| Molecular Alterations and Buparlisib Efficacy in Patients with Squamous Cell Carcinoma of the Head and Neck: Biomarker Analysis from BERIL-1. | Q52680878 | ||
| PI3K pathway inhibitors approach junction | Q54570634 | ||
| Loss of PTEN-assisted G2/M checkpoint impedes homologous recombination repair and enhances radio-curability and PARP inhibitor treatment response in prostate cancer. | Q55371418 | ||
| Dual blockade of PI3K and MEK in combination with radiation in head and neck cancer. | Q55689566 | ||
| Alcohol Drinking in Never Users of Tobacco, Cigarette Smoking in Never Drinkers, and the Risk of Head and Neck Cancer: Pooled Analysis in the International Head and Neck Cancer Epidemiology Consortium | Q57559757 | ||
| Global cancer statistics 2018: GLOBOCAN estimates of incidence and mortality worldwide for 36 cancers in 185 countries | Q60142201 | ||
| Buparlisib with thoracic radiotherapy and its effect on tumour hypoxia: A phase I study in patients with advanced non-small cell lung carcinoma | Q64074090 | ||
| Head and neck cancer | Q77387887 | ||
| Dual Inhibition of the PI3K/mTOR Pathway Increases Tumor Radiosensitivity by Normalizing Tumor Vasculature | Q82638153 | ||
| Cotargeting BCL-2 and PI3K Induces BAX-Dependent Mitochondrial Apoptosis in AML Cells | Q88112398 | ||
| Differential compensation mechanisms define resistance to PI3K inhibitors in PIK3CA amplified HNSCC | Q89181553 | ||
| Radiosensitization approaches for HPV-positive and HPV-negative head and neck squamous carcinomas | Q91702037 | ||
| Alpelisib: First Global Approval | Q93133555 | ||
| P433 | issue | 1 | |
| P921 | main subject | head and neck cancer | Q1783924 |
| head and neck carcinoma | Q18554836 | ||
| neck cancer | Q18966654 | ||
| P304 | page(s) | 16208 | |
| P577 | publication date | 2020-10-01 | |
| P1433 | published in | Scientific Reports | Q2261792 |
| P1476 | title | The influence of PI3K inhibition on the radiotherapy response of head and neck cancer cells | |
| P478 | volume | 10 |
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