PorA, a conserved C-terminal domain-containing protein, impacts the PorXY-SigP signaling of the type IX secretion system

scientific article published on 03 December 2020

PorA, a conserved C-terminal domain-containing protein, impacts the PorXY-SigP signaling of the type IX secretion system is …
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scholarly articleQ13442814

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P356DOI10.1038/S41598-020-77987-Y
P932PMC publication ID7712824
P698PubMed publication ID33273542

P50authorMariko NaitoQ114019319
P2093author name stringKatsumi Imada
Hideharu Yukitake
Keiko Sato
Koji Nakayama
Mikio Shoji
Yusuke Handa
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Porphyromonas gingivalis Type IX Secretion Substrates Are Cleaved and Modified by a Sortase-Like MechanismQ28547754
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A protein secretion system linked to bacteroidete gliding motility and pathogenesisQ30492785
Structural classification of bacterial response regulators: diversity of output domains and domain combinationsQ33245450
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Tetratricopeptide repeat protein-associated proteins contribute to the virulence of Porphyromonas gingivalisQ33877275
Por secretion system-dependent secretion and glycosylation of Porphyromonas gingivalis hemin-binding protein 35.Q33952348
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The multiple forms of trypsin-like activity present in various strains of Porphyromonas gingivalis are due to the presence of either Arg-gingipain or Lys-gingipainQ35397754
Analysis of the Streptomyces coelicolor sigE gene reveals the existence of a subfamily of eubacterial RNA polymerase sigma factors involved in the regulation of extracytoplasmic functionsQ35648817
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PG0026 is the C-terminal signal peptidase of a novel secretion system of Porphyromonas gingivalisQ36098046
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The outer-membrane export signal of Porphyromonas gingivalis type IX secretion system (T9SS) is a conserved C-terminal β-sandwich domainQ36719608
Sequence-independent processing site of the C-terminal domain (CTD) influences maturation of the RgpB protease from Porphyromonas gingivalisQ37171621
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Glycobiology of the oral pathogen Porphyromonas gingivalis and related speciesQ38604580
SigCH, an extracytoplasmic function sigma factor of Porphyromonas gingivalis regulates the expression of cdhR and hmuYR.Q39112064
A two-component system regulates gene expression of the type IX secretion component proteins via an ECF sigma factorQ39240953
Themes and variations in gene regulation by extracytoplasmic function (ECF) sigma factorsQ39346572
Type IX secretion: the generation of bacterial cell surface coatings involved in virulence, gliding motility and the degradation of complex biopolymers.Q39438640
Involvement of the Wbp pathway in the biosynthesis of Porphyromonas gingivalis lipopolysaccharide with anionic polysaccharideQ39884788
Studies of the extracytoplasmic function sigma factor PG0162 in Porphyromonas gingivalisQ40690135
A functional virulence complex composed of gingipains, adhesins, and lipopolysaccharide shows high affinity to host cells and matrix proteins and escapes recognition by host immune systemsQ40997028
PorV is an Outer Membrane Shuttle Protein for the Type IX Secretion System.Q41459114
Role of Mfa5 in Expression of Mfa1 Fimbriae in Porphyromonas gingivalis.Q41551370
Identification of an O-antigen chain length regulator, WzzP, in Porphyromonas gingivalis.Q41898463
The periodontopathogen Porphyromonas gingivalis binds iron protoporphyrin IX in the mu-oxo dimeric form: an oxidative buffer and possible pathogenic mechanismQ42115902
Construction of recombinant hemagglutinin derived from the gingipain-encoding gene of Porphyromonas gingivalis, identification of its target protein on erythrocytes, and inhibition of hemagglutination by an interdomain regional peptideQ42618490
Construction and characterization of a nonpigmented mutant of Porphyromonas gingivalis: cell surface polysaccharide as an anchorage for gingipainsQ42673712
Porphyromonas gingivalis mutant defective in a putative extracytoplasmic function sigma factor shows a mutator phenotypeQ43287079
Cloning of a Bacteroides gingivalis outer membrane protein gene in Escherichia coliQ44186665
Identification of Porphyromonas gingivalis proteins secreted by the Por secretion systemQ44705620
The major structural components of two cell surface filaments of Porphyromonas gingivalis are matured through lipoprotein precursorsQ44912264
Diverse C-Terminal Sequences Involved in Flavobacterium johnsoniae Protein Secretion.Q44971723
Identification of a new membrane-associated protein that influences transport/maturation of gingipains and adhesins of Porphyromonas gingivalisQ45213234
Porphyromonas gingivalis C-terminal signal peptidase PG0026 and HagA interact with outer membrane protein PG27/LptO.Q45346359
Characterization of RagA and RagB in Porphyromonas gingivalis: study using gene-deletion mutantsQ46927591
Involvement of a lysine-specific cysteine proteinase in hemoglobin adsorption and heme accumulation by Porphyromonas gingivalisQ47724105
Design and Preparation of the Fragment Proteins of the Flagellar Components Suitable for X-Ray Crystal Structure Analysis.Q51066615
Analysis of a Lys-specific serine endopeptidase secreted via the type IX secretion system in Porphyromonas gingivalis.Q53061256
Dropping anchor: attachment of peptidylarginine deiminase via A-LPS to secreted outer membrane vesicles of Porphyromonas gingivalis.Q55279783
Immunoglobulin-like domains of the cargo proteins are essential for protein stability during secretion by the type IX secretion systemQ58036642
Type 9 secretion system structures reveal a new protein transport mechanismQ58599951
Arg-gingipain acts as a major processing enzyme for various cell surface proteins in Porphyromonas gingivalisQ64449894
Genetic analyses of proteolysis, hemoglobin binding, and hemagglutination of Porphyromonas gingivalis. Construction of mutants with a combination of rgpA, rgpB, kgp, and hagAQ77863752
Protein substrates of a novel secretion system are numerous in the Bacteroidetes phylum and have in common a cleavable C-terminal secretion signal, extensive post-translational modification, and cell-surface attachmentQ85639692
PGN_0297 is an essential component of the type IX secretion system (T9SS) in Porphyromonas gingivalis: Tn-seq analysis for exhaustive identification of T9SS-related genesQ90836038
The Carboxy-Terminal Region of Flavobacterium johnsoniae SprB Facilitates Its Secretion by the Type IX Secretion System and Propulsion by the Gliding Motility MachineryQ91526697
Diverse Bacterial Genes Modulate Plant Root Association by Beneficial BacteriaQ104479285
P433issue1
P304page(s)21109
P577publication date2020-12-03
P1433published inScientific ReportsQ2261792
P1476titlePorA, a conserved C-terminal domain-containing protein, impacts the PorXY-SigP signaling of the type IX secretion system
P478volume10

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