scholarly article | Q13442814 |
P356 | DOI | 10.1074/JBC.274.25.17955 |
P698 | PubMed publication ID | 10364243 |
P2093 | author name string | K Yamamoto | |
K Nakayama | |||
Y Shi | |||
N Abe | |||
K Okamoto | |||
D B Ratnayake | |||
P433 | issue | 25 | |
P407 | language of work or name | English | Q1860 |
P921 | main subject | proteolysis | Q33123 |
Porphyromonas gingivalis | Q3214147 | ||
P1104 | number of pages | 6 | |
P304 | page(s) | 17955-17960 | |
P577 | publication date | 1999-06-01 | |
P1433 | published in | Journal of Biological Chemistry | Q867727 |
P1476 | title | Genetic analyses of proteolysis, hemoglobin binding, and hemagglutination of Porphyromonas gingivalis. Construction of mutants with a combination of rgpA, rgpB, kgp, and hagA | |
P478 | volume | 274 |
Q37596229 | 8-oxo-7,8-dihydroguanine is removed by a nucleotide excision repair-like mechanism in Porphyromonas gingivalis W83. |
Q38916275 | A Porphyromonas gingivalis Periplasmic Novel Exopeptidase, Acylpeptidyl Oligopeptidase, Releases N-Acylated Di- and Tripeptides from Oligopeptides |
Q33631022 | A Porphyromonas gingivalis mutant defective in a putative glycosyltransferase exhibits defective biosynthesis of the polysaccharide portions of lipopolysaccharide, decreased gingipain activities, strong autoaggregation, and increased biofilm formati |
Q42081808 | A combination of both arginine- and lysine-specific gingipain activity of Porphyromonas gingivalis is necessary for the generation of the micro-oxo bishaem-containing pigment from haemoglobin. |
Q40997028 | A functional virulence complex composed of gingipains, adhesins, and lipopolysaccharide shows high affinity to host cells and matrix proteins and escapes recognition by host immune systems |
Q47364041 | A novel peptidic inhibitor derived from Streptococcus cristatus ArcA attenuates virulence potential of Porphyromonas gingivalis. |
Q30492785 | A protein secretion system linked to bacteroidete gliding motility and pathogenesis |
Q39240953 | A two-component system regulates gene expression of the type IX secretion component proteins via an ECF sigma factor |
Q32155652 | Acquisition of iron from human transferrin by Porphyromonas gingivalis: a role for Arg- and Lys-gingipain activities |
Q44425221 | Adhesins encoded by the gingipain genes of Porphyromonas gingivalis are responsible for co-aggregation with Prevotella intermedia |
Q64100240 | Adhesive protein-mediated cross-talk between Candida albicans and Porphyromonas gingivalis in dual species biofilm protects the anaerobic bacterium in unfavorable oxic environment |
Q35755292 | Antigens of bacteria associated with periodontitis. |
Q43181650 | Association between epithelial cell death and invasion by microspheres conjugated to Porphyromonas gingivalis vesicles with different types of fimbriae |
Q38922535 | Attenuation of the phosphatidylinositol 3-kinase/Akt signaling pathway by Porphyromonas gingivalis gingipains RgpA, RgpB, and Kgp. |
Q39771727 | Bacteria-derived hydrogen sulfide promotes IL-8 production from epithelial cells. |
Q33879806 | Bacterial heme sources: the role of heme, hemoprotein receptors and hemophores |
Q37015215 | Binding of complement inhibitor C4b-binding protein contributes to serum resistance of Porphyromonas gingivalis |
Q33996913 | Binding specificity of the Porphyromonas gingivalis heme and hemoglobin receptor HmuR, gingipain K, and gingipain R1 for heme, porphyrins, and metalloporphyrins |
Q30834227 | CPG70 is a novel basic metallocarboxypeptidase with C-terminal polycystic kidney disease domains from Porphyromonas gingivalis. |
Q39520913 | Calprotectin expression in vitro by oral epithelial cells confers resistance to infection by Porphyromonas gingivalis |
Q34886897 | Cardiovascular disease and the role of oral bacteria |
Q50020356 | Cell cycle arrest and apoptosis induced by Porphyromonas gingivalis requires JNK- and p53-mediated p38 activation in human trophoblasts |
Q57295298 | Characterization and development of SAPP as a specific peptidic inhibitor that targets Porphyromonas gingivalis |
Q33586891 | Characterization of hemin-binding protein 35 (HBP35) in Porphyromonas gingivalis: its cellular distribution, thioredoxin activity and role in heme utilization |
Q34011300 | Characterization of the Plesiomonas shigelloides genes encoding the heme iron utilization system |
Q34301436 | Cleavage of extracellular matrix in periodontitis: gingipains differentially affect cell adhesion activities of fibronectin and tenascin-C. |
Q41195120 | Cleavage of human transferrin by Porphyromonas gingivalis gingipains promotes growth and formation of hydroxyl radicals |
Q39824564 | Cleavage of protease-activated receptors on an immortalized oral epithelial cell line by Porphyromonas gingivalis gingipains. |
Q35668006 | Comprehensive transcriptome analysis of the periodontopathogenic bacterium Porphyromonas gingivalis W83. |
Q42618490 | Construction of recombinant hemagglutinin derived from the gingipain-encoding gene of Porphyromonas gingivalis, identification of its target protein on erythrocytes, and inhibition of hemagglutination by an interdomain regional peptide |
Q48255950 | Degradation of Incretins and Modulation of Blood Glucose Levels by Periodontopathic Bacterial Dipeptidyl Peptidase 4. |
Q33996920 | Degradation of host heme proteins by lysine- and arginine-specific cysteine proteinases (gingipains) of Porphyromonas gingivalis. |
Q59136826 | Deletion of a conserved transcript PG_RS02100 expressed during logarithmic growth in Porphyromonas gingivalis results in hyperpigmentation and increased tolerance to oxidative stress |
Q22066058 | Determination of the genome sequence of Porphyromonas gingivalis strain ATCC 33277 and genomic comparison with strain W83 revealed extensive genome rearrangements in P. gingivalis |
Q34076596 | Dichotomy of gingipains action as virulence factors: from cleaving substrates with the precision of a surgeon's knife to a meat chopper-like brutal degradation of proteins. |
Q33852308 | Differential response of Porphyromonas gingivalis to varying levels and duration of hydrogen peroxide-induced oxidative stress |
Q39656552 | Discrete proteolysis of focal contact and adherens junction components in Porphyromonas gingivalis-infected oral keratinocytes: a strategy for cell adhesion and migration disabling. |
Q33452861 | Distinct roles of long/short fimbriae and gingipains in homotypic biofilm development by Porphyromonas gingivalis |
Q39487934 | Distribution of Porphyromonas gingivalis biotypes defined by alleles of the kgp (Lys-gingipain) gene |
Q42957420 | Does the importance of the C-terminal residues in the maturation of RgpB from Porphyromonas gingivalis reveal a novel mechanism for protein export in a subgroup of Gram-Negative bacteria? |
Q92513828 | Effect of deletion of the rgpA gene on selected virulence of Porphyromonas gingivalis |
Q41997090 | Effect of extracytoplasmic function sigma factors on autoaggregation, hemagglutination, and cell surface properties of Porphyromonas gingivalis. |
Q33187831 | Effect of inactivation of the Arg- and/or Lys-gingipain gene on selected virulence and physiological properties of Porphyromonas gingivalis |
Q24645315 | Entry of Porphyromonas gingivalis outer membrane vesicles into epithelial cells causes cellular functional impairment |
Q39241833 | Exopeptidases and gingipains in Porphyromonas gingivalis as prerequisites for its amino acid metabolism |
Q24642308 | Gingipain enzymes from Porphyromonas gingivalis preferentially bind immobilized extracellular proteins: a mechanism favouring colonization? |
Q24630104 | Gingipain-dependent interactions with the host are important for survival of Porphyromonas gingivalis |
Q38182102 | Gingipains from Porphyromonas gingivalis - Complex domain structures confer diverse functions |
Q36711718 | Gingipains: Critical Factors in the Development of Aspiration Pneumonia Caused by Porphyromonas gingivalis |
Q44695410 | Hemoglobin hydrolysis and heme acquisition by Porphyromonas gingivalis |
Q39078386 | Hemoglobin receptor protein from Porphyromonas gingivalis induces interleukin-8 production in human gingival epithelial cells through stimulation of the mitogen-activated protein kinase and NF-κB signal transduction pathways |
Q39900355 | High molecular weight gingipains from Porphyromonas gingivalis induce cytokine responses from human macrophage-like cells via a nonproteolytic mechanism |
Q34072532 | Highly specific protease-based approach for detection of porphyromonas gingivalis in diagnosis of periodontitis. |
Q36575351 | Humoral responses to Porphyromonas gingivalis gingipain adhesin domains in subjects with chronic periodontitis |
Q41984188 | Identification and characterization of prokaryotic dipeptidyl-peptidase 5 from Porphyromonas gingivalis |
Q35508052 | Identification of Dipeptidyl-Peptidase (DPP)5 and DPP7 in Porphyromonas endodontalis, Distinct from Those in Porphyromonas gingivalis |
Q38687979 | Identification of Streptococcus cristatus peptides that repress expression of virulence genes in Porphyromonas gingivalis. |
Q33492148 | Identification of a gingipain-sensitive surface ligand of Porphyromonas gingivalis that induces Toll-like receptor 2- and 4-independent NF-kappaB activation in CHO cells |
Q34334143 | Identification of amino acid residues involved in heme binding and hemoprotein utilization in the Porphyromonas gingivalis heme receptor HmuR. |
Q41898463 | Identification of an O-antigen chain length regulator, WzzP, in Porphyromonas gingivalis. |
Q36211069 | Identification of signaling pathways mediating cell cycle arrest and apoptosis induced by Porphyromonas gingivalis in human trophoblasts |
Q39654838 | Immunization with the RgpA-Kgp proteinase-adhesin complexes of Porphyromonas gingivalis protects against periodontal bone loss in the rat periodontitis model |
Q41195310 | In vitro models of tissue penetration and destruction by Porphyromonas gingivalis |
Q33883348 | Inactivation of vimF, a putative glycosyltransferase gene downstream of vimE, alters glycosylation and activation of the gingipains in Porphyromonas gingivalis W83. |
Q38897738 | Inhibition of gingipains and Porphyromonas gingivalis growth and biofilm formation by prenyl flavonoids |
Q64449483 | Interaction of Porphyromonas gingivalis with KB cells: comparison of different clinical isolates |
Q34009791 | Intra- and interspecies regulation of gene expression by Actinobacillus actinomycetemcomitans LuxS. |
Q41476453 | Invasion of epithelial cells and proteolysis of cellular focal adhesion components by distinct types of Porphyromonas gingivalis fimbriae |
Q36410939 | Involvement of an Skp-Like Protein, PGN_0300, in the Type IX Secretion System of Porphyromonas gingivalis |
Q42385791 | Involvement of extracytoplasmic function sigma factors in virulence regulation in Porphyromonas gingivalis W83 |
Q39884788 | Involvement of the Wbp pathway in the biosynthesis of Porphyromonas gingivalis lipopolysaccharide with anionic polysaccharide |
Q33675274 | Metal uptake in host-pathogen interactions: role of iron in Porphyromonas gingivalis interactions with host organisms |
Q47334710 | Molecular mechanisms of Porphyromonas gingivalis-host cell interaction on periodontal diseases |
Q73866307 | Monoclonal antibody against Porphyromonas gingivalis hemagglutinin inhibits hemolytic activity |
Q37153667 | Mucosal Langerhans Cells Promote Differentiation of Th17 Cells in a Murine Model of Periodontitis but Are Not Required for Porphyromonas gingivalis-Driven Alveolar Bone Destruction |
Q35833765 | Noncanonical activation of β-catenin by Porphyromonas gingivalis |
Q64265564 | Oral Mucosal Epithelial Cells |
Q33952348 | Por secretion system-dependent secretion and glycosylation of Porphyromonas gingivalis hemin-binding protein 35. |
Q104064523 | PorA, a conserved C-terminal domain-containing protein, impacts the PorXY-SigP signaling of the type IX secretion system |
Q41459114 | PorV is an Outer Membrane Shuttle Protein for the Type IX Secretion System. |
Q34892870 | Porphyrin-mediated cell surface heme capture from hemoglobin by Porphyromonas gingivalis |
Q35983505 | Porphyromonas gingivalis Gingipain-Dependently Enhances IL-33 Production in Human Gingival Epithelial Cells. |
Q29028828 | Porphyromonas gingivalis Gingipains Trigger a Proinflammatory Response in Human Monocyte-derived Macrophages Through the p38α Mitogen-activated Protein Kinase Signal Transduction Pathway |
Q26850410 | Porphyromonas gingivalis and related bacteria: from colonial pigmentation to the type IX secretion system and gliding motility |
Q61037930 | Porphyromonas gingivalis in Alzheimer's disease brains: Evidence for disease causation and treatment with small-molecule inhibitors. |
Q33454003 | Porphyromonas gingivalis induce apoptosis in human gingival epithelial cells through a gingipain-dependent mechanism |
Q36575882 | Porphyromonas gingivalis induces receptor activator of NF-kappaB ligand expression in osteoblasts through the activator protein 1 pathway |
Q34236546 | Porphyromonas gingivalis peptidoglycans induce excessive activation of the innate immune system in silkworm larvae. |
Q39102655 | Porphyromonas gingivalis promotes invasion of oral squamous cell carcinoma through induction of proMMP9 and its activation |
Q40118000 | Porphyromonas gingivalis suppresses invasion of Fusobacterium nucleatum into gingival epithelial cells. |
Q57045926 | Porphyromonas gingivalis triggers NLRP3-mediated inflammasome activation in macrophages in a bacterial gingipains-independent manner |
Q99565601 | Probiotics alter biofilm formation and the transcription of Porphyromonas gingivalis virulence-associated genes |
Q34769946 | Propeptide-mediated inhibition of cognate gingipain proteinases. |
Q39730048 | Purification, gene cloning, gene expression, and mutants of Dps from the obligate anaerobe Porphyromonas gingivalis |
Q101038893 | Quercetin inhibits virulence properties of Porphyromas gingivalis in periodontal disease |
Q89143062 | Regulation of the Peptidoglycan Amidase PGLYRP2 in Epithelial Cells by Interleukin-36γ |
Q36425009 | Resistance of Porphyromonas gingivalis ATCC 33277 to direct killing by antimicrobial peptides is protease independent |
Q37075590 | Response of Porphyromonas gingivalis to heme limitation in continuous culture. |
Q64982172 | Riemerella anatipestifer GldM is required for bacterial gliding motility, protein secretion, and virulence. |
Q47221520 | Riemerella anatipestifer Type IX Secretion System Is Required for Virulence and Gelatinase Secretion |
Q42799322 | Role for gingipains in Porphyromonas gingivalis traffic to phagolysosomes and survival in human aortic endothelial cells |
Q34009727 | Role of RgpA, RgpB, and Kgp proteinases in virulence of Porphyromonas gingivalis W50 in a murine lesion model |
Q24548657 | Role of gingipains in growth of Porphyromonas gingivalis in the presence of human serum albumin |
Q42078203 | Saliva enables the antimicrobial activity of LL-37 in the presence of proteases of Porphyromonas gingivalis |
Q83293247 | Selective inhibition of Porphyromonas gingivalis growth by a factor Xa inhibitor, DX-9065a |
Q39503928 | Signaling system in Porphyromonas gingivalis based on a LuxS protein |
Q33996474 | Sodium ion-driven serine/threonine transport in Porphyromonas gingivalis |
Q34007214 | Specific antibodies to Porphyromonas gingivalis Lys-gingipain by DNA vaccination inhibit bacterial binding to hemoglobin and protect mice from infection |
Q37435146 | Structural and functional probing of PorZ, an essential bacterial surface component of the type-IX secretion system of human oral-microbiomic Porphyromonas gingivalis. |
Q30152912 | Structural and mutational analyses of dipeptidyl peptidase 11 from Porphyromonas gingivalis reveal the molecular basis for strict substrate specificity. |
Q43666241 | Studies on the aminopeptidase activities of Porphyromonas gingivalis |
Q34129081 | Subgingival colonization by Porphyromonas gingivalis |
Q34521878 | Temporal activation of anti- and pro-apoptotic factors in human gingival fibroblasts infected with the periodontal pathogen, Porphyromonas gingivalis: potential role of bacterial proteases in host signalling |
Q42682829 | The K1K2 region of Lys-gingipain of Porphyromonas gingivalis blocks induction of HLA expression by gamma interferon |
Q35075282 | The RgpB C-terminal domain has a role in attachment of RgpB to the outer membrane and belongs to a novel C-terminal-domain family found in Porphyromonas gingivalis |
Q33729399 | The Type IX Secretion System (T9SS): Highlights and Recent Insights into Its Structure and Function. |
Q44426303 | The collagenase activity ofPorphyromonas gingivalisis due to Arg-gingipain |
Q34601780 | The hemoglobin receptor protein of porphyromonas gingivalis inhibits receptor activator NF-kappaB ligand-induced osteoclastogenesis from bone marrow macrophages |
Q37279079 | The host cytokine response to Porphyromonas gingivalis is modified by gingipains |
Q27680674 | The lysine gingipain adhesin domains from Porphyromonas gingivalis interact with erythrocytes and albumin: Structures correlate to function |
Q37522801 | The vimE gene downstream of vimA is independently expressed and is involved in modulating proteolytic activity in Porphyromonas gingivalis W83. |
Q92157140 | Triggering NETosis via protease-activated receptor (PAR)-2 signaling as a mechanism of hijacking neutrophils function for pathogen benefits |
Q30160350 | Trimeric structure of major outer membrane proteins homologous to OmpA in Porphyromonas gingivalis. |
Q36366485 | Using Tn-seq To Identify Pigmentation-Related Genes of Porphyromonas gingivalis: Characterization of the Role of a Putative Glycosyltransferase |
Q44557445 | Virulence factors of Porphyromonas gingivalis are modified by polyphenol oxidase and asparaginase |
Q34523264 | luxS and arcB control aerobic growth of Actinobacillus actinomycetemcomitans under iron limitation |
Q34005626 | vimA gene downstream of recA is involved in virulence modulation in Porphyromonas gingivalis W83. |
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