A Porphyromonas gingivalis mutant defective in a putative glycosyltransferase exhibits defective biosynthesis of the polysaccharide portions of lipopolysaccharide, decreased gingipain activities, strong autoaggregation, and increased biofilm formati

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A Porphyromonas gingivalis mutant defective in a putative glycosyltransferase exhibits defective biosynthesis of the polysaccharide portions of lipopolysaccharide, decreased gingipain activities, strong autoaggregation, and increased biofilm formati is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.1128/IAI.00071-10
P8608Fatcat IDrelease_lg345fotqre45cucuuvn7uubea
P932PMC publication ID2937442
P698PubMed publication ID20624909

P2093author name stringShigeyuki Ebisu
Yuichiro Noiri
Hideharu Yukitake
Keiko Sato
Koji Nakayama
Mikiyo Yamaguchi
P2860cites workDetermination of the genome sequence of Porphyromonas gingivalis strain ATCC 33277 and genomic comparison with strain W83 revealed extensive genome rearrangements in P. gingivalisQ22066058
Differential lipopolysaccharide core capping leads to quantitative and correlated modifications of mechanical and structural properties in Pseudomonas aeruginosa biofilmsQ28492796
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Pleiotropic pigmentation mutants of Porphyromonas gingivalisQ30857715
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Genetic variation of Porphyromonas gingivalis genes encoding gingipains, cysteine proteinases with arginine or lysine specificityQ48039254
A cell-associated protein complex of Porphyromonas gingivalis W50 composed of Arg- and Lys-specific cysteine proteinases and adhesinsQ48047767
Domain-specific rearrangement between the two Arg-gingipain-encoding genes in Porphyromonas gingivalis: possible involvement of nonreciprocal recombinationQ48055797
Identification of a Porphyromonas gingivalis novel protein sov required for the secretion of gingipainsQ48078707
Novel stationary-phase-upregulated protein of Porphyromonas gingivalis influences production of superoxide dismutase, thiol peroxidase and thioredoxinQ48147411
Effect of host responses on the pathogenicity of strains of Porphyromonas gingivalis.Q51194193
Construction and characterization of arginine-specific cysteine proteinase (Arg-gingipain)-deficient mutants of Porphyromonas gingivalis. Evidence for significant contribution of Arg-gingipain to virulence.Q52508036
K-antigens in Porphyromonas gingivalis are associated with virulence.Q54229629
Haemin binding as a factor in the virulence of Porphyromonas gingivalisQ71419305
Novel polysaccharide capsular serotypes in Porphyromonas gingivalisQ71549792
Transposon-induced pigment-deficient mutants of Porphyromonas gingivalisQ71989746
Studying biofilm formation of mutans streptococciQ73147765
Peptostreptococcus micros coaggregates with Fusobacterium nucleatum and non-encapsulated Porphyromonas gingivalisQ73305571
Isolation and characterization of the cell-surface polysaccharides of Porphyromonas gingivalis ATCC 53978Q73388183
Adhesion of Porphyromonas gingivalis serotypes to pocket epitheliumQ73723736
Haemoglobin receptor protein is intragenically encoded by the cysteine proteinase-encoding genes and the haemagglutinin-encoding gene of Porphyromonas gingivalisQ74183899
Genetic analyses of proteolysis, hemoglobin binding, and hemagglutination of Porphyromonas gingivalis. Construction of mutants with a combination of rgpA, rgpB, kgp, and hagAQ77863752
VimA is part of the maturation pathway for the major gingipains of Porphyromonas gingivalis W83Q79317261
Sequential action of R- and K-specific gingipains of Porphyromonas gingivalis in the generation of the haem-containing pigment from oxyhaemoglobinQ80496884
Identification and cloning of genes from Porphyromonas gingivalis after mutagenesis with a modified Tn4400 transposon from Bacteroides fragilisQ95759788
Participation of bacterial biofilms in refractory and chronic periapical periodontitisQ30867135
Bacterial interactions and successions during plaque developmentQ33255111
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Distinct roles of long/short fimbriae and gingipains in homotypic biofilm development by Porphyromonas gingivalisQ33452861
Altered gingipain maturation in vimA- and vimE-defective isogenic mutants of Porphyromonas gingivalisQ33716035
Genetics of O-antigen biosynthesis in Pseudomonas aeruginosaQ33728775
Tetratricopeptide repeat protein-associated proteins contribute to the virulence of Porphyromonas gingivalisQ33877275
Inactivation of vimF, a putative glycosyltransferase gene downstream of vimE, alters glycosylation and activation of the gingipains in Porphyromonas gingivalis W83.Q33883348
Variable carbohydrate modifications to the catalytic chains of the RgpA and RgpB proteases of Porphyromonas gingivalis W50.Q34001332
Life below the gum line: pathogenic mechanisms of Porphyromonas gingivalisQ34010067
Factors in virulence expression and their role in periodontal disease pathogenesisQ34015505
Subgingival colonization by Porphyromonas gingivalisQ34129081
Identification and localization of extraradicular biofilm-forming bacteria associated with refractory endodontic pathogensQ34232276
Identification and characterization of the capsular polysaccharide (K-antigen) locus of Porphyromonas gingivalisQ34300876
Molecular cloning and structural characterization of the Arg-gingipain proteinase of Porphyromonas gingivalis. Biosynthesis as a proteinase-adhesin polyproteinQ34317271
Molecular basis for structural diversity in the core regions of the lipopolysaccharides of Escherichia coli and Salmonella entericaQ34477515
The RgpB C-terminal domain has a role in attachment of RgpB to the outer membrane and belongs to a novel C-terminal-domain family found in Porphyromonas gingivalisQ35075282
Porphyromonas gingivalis galE is involved in lipopolysaccharide O-antigen synthesis and biofilm formationQ35217619
The multiple forms of trypsin-like activity present in various strains of Porphyromonas gingivalis are due to the presence of either Arg-gingipain or Lys-gingipainQ35397754
Membrane morphology and leukotoxin secretion are associated with a novel membrane protein of Aggregatibacter actinomycetemcomitansQ36845546
High surface hydrophobicity of autoaggregating Staphylococcus aureus strains isolated from human infections studied with the salt aggregation testQ37075427
Essential role for the gtfA gene encoding a putative glycosyltransferase in the adherence of Porphyromonas gingivalisQ37426598
The assembly system for the outer core portion of R1- and R4-type lipopolysaccharides of Escherichia coli. The R1 core-specific beta-glucosyltransferase provides a novel attachment site for O-polysaccharides.Q38331959
Purification, gene cloning, gene expression, and mutants of Dps from the obligate anaerobe Porphyromonas gingivalisQ39730048
Procedure for isolation of bacterial lipopolysaccharides from both smooth and rough Pseudomonas aeruginosa and Salmonella typhimurium strains.Q39976568
Functional characterization of extracellular vesicles produced by Bacteroides gingivalisQ40162271
Pathogenic strategies of the oral anaerobe, Porphyromonas gingivalisQ40512781
Biosynthesis and expression of cell-surface polysaccharides in gram-negative bacteria.Q40815635
A functional virulence complex composed of gingipains, adhesins, and lipopolysaccharide shows high affinity to host cells and matrix proteins and escapes recognition by host immune systemsQ40997028
Enhanced biofilm formation and loss of capsule synthesis: deletion of a putative glycosyltransferase in Porphyromonas gingivalisQ41953132
Major outer membrane proteins and proteolytic processing of RgpA and Kgp of Porphyromonas gingivalis W50.Q42157652
Construction of recombinant hemagglutinin derived from the gingipain-encoding gene of Porphyromonas gingivalis, identification of its target protein on erythrocytes, and inhibition of hemagglutination by an interdomain regional peptideQ42618490
Cloning and sequencing of the gene encoding a novel lysine-specific cysteine proteinase (Lys-gingipain) in Porphyromonas gingivalis: structural relationship with the arginine-specific cysteine proteinase (Arg-gingipain).Q42642365
Construction and characterization of a nonpigmented mutant of Porphyromonas gingivalis: cell surface polysaccharide as an anchorage for gingipainsQ42673712
Structural analysis of the core region of O-lipopolysaccharide of Porphyromonas gingivalis from mutants defective in O-antigen ligase and O-antigen polymerase.Q43071859
Identification of a new membrane-associated protein that influences transport/maturation of gingipains and adhesins of Porphyromonas gingivalisQ45213234
Lipopolysaccharide biosynthesis-related genes are required for colony pigmentation of Porphyromonas gingivalisQ46068529
PG27 is a novel membrane protein essential for a Porphyromonas gingivalis protease secretion systemQ46136593
Structural analysis of a novel anionic polysaccharide from Porphyromonas gingivalis strain W50 related to Arg-gingipain glycansQ46765229
Biochemical and functional properties of lysine-specific cysteine proteinase (Lys-gingipain) as a virulence factor of Porphyromonas gingivalis in periodontal diseaseQ46859545
Characterization of RagA and RagB in Porphyromonas gingivalis: study using gene-deletion mutantsQ46927591
P433issue9
P407language of work or nameEnglishQ1860
P921main subjectpolysaccharideQ134219
lipopolysaccharideQ421804
biofilmQ467410
Porphyromonas gingivalisQ3214147
P304page(s)3801-3812
P577publication date2010-07-12
P1433published inInfection and ImmunityQ6029193
P1476titleA Porphyromonas gingivalis mutant defective in a putative glycosyltransferase exhibits defective biosynthesis of the polysaccharide portions of lipopolysaccharide, decreased gingipain activities, strong autoaggregation, and increased biofilm formati
P478volume78

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cites work (P2860)
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