Gingipain enzymes from Porphyromonas gingivalis preferentially bind immobilized extracellular proteins: a mechanism favouring colonization?

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Gingipain enzymes from Porphyromonas gingivalis preferentially bind immobilized extracellular proteins: a mechanism favouring colonization? is …
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scholarly articleQ13442814

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P356DOI10.1111/J.1600-0765.2008.01128.X
P932PMC publication ID2718433
P698PubMed publication ID18973544
P5875ResearchGate publication ID23441134

P50authorJan PotempaQ11718746
Aneta SrokaQ59660101
P2093author name stringA D McAlister
J Travis
N S Quinsey
R E Fitzpatrick
R N Pike
P2860cites workInactivation of membrane tumor necrosis factor alpha by gingipains from Porphyromonas gingivalisQ33716115
Degradation of host heme proteins by lysine- and arginine-specific cysteine proteinases (gingipains) of Porphyromonas gingivalis.Q33996920
Porphyromonas gingivalis RgpA and Kgp proteinases and adhesins are C terminally processed by the carboxypeptidase CPG70.Q34143471
Molecular cloning and structural characterization of the Arg-gingipain proteinase of Porphyromonas gingivalis. Biosynthesis as a proteinase-adhesin polyproteinQ34317271
Purification and characterization of a 50-kDa cysteine proteinase (gingipain) from Porphyromonas gingivalisQ34335344
Lysine- and arginine-specific proteinases from Porphyromonas gingivalis. Isolation, characterization, and evidence for the existence of complexes with hemagglutininsQ34347503
Inhibitory effects of Porphyromonas gingivalis fimbriae on interactions between extracellular matrix proteins and cellular integrinsQ34395151
The hemagglutinin gene A (hagA) of Porphyromonas gingivalis 381 contains four large, contiguous, direct repeats.Q35522174
A role for fimbriae in Porphyromonas gingivalis invasion of oral epithelial cellsQ35547810
Characterization of the binding activities of proteinase-adhesin complexes from Porphyromonas gingivalisQ35607423
Characterization of an adherence and antigenic determinant of the ArgI protease of Porphyromonas gingivalis which is present on multiple gene products.Q38355964
Functional differences among FimA variants of Porphyromonas gingivalis and their effects on adhesion to and invasion of human epithelial cellsQ39653533
Isolation and characterization of a minor fimbria from Porphyromonas gingivalisQ39826640
Construction and characterization of a fimA mutant of Porphyromonas gingivalisQ39860055
Major outer membrane proteins and proteolytic processing of RgpA and Kgp of Porphyromonas gingivalis W50.Q42157652
Fluorescence energy transfer detects changes in fibronectin structure upon surface bindingQ42202994
The cloning, expression and sequence analysis of a second Porphyromonas gingivalis gene that codes for a protein involved in hemagglutinationQ42627873
Duplication and differential expression of hemagglutinin genes in Porphyromonas gingivalisQ42645223
Involvement of integrins in fimbriae-mediated binding and invasion by Porphyromonas gingivalis.Q44004516
Adhesins encoded by the gingipain genes of Porphyromonas gingivalis are responsible for co-aggregation with Prevotella intermediaQ44425221
The C-terminal domains of the gingipain K polyprotein are necessary for assembly of the active enzyme and expression of associated activitiesQ45156919
The expression and function of a Bacteroides gingivalis hemagglutinin gene in Escherichia coliQ45769610
Molecular cloning and characterization of Porphyromonas gingivalis lysine-specific gingipain. A new member of an emerging family of pathogenic bacterial cysteine proteinasesQ46086294
Biochemical and functional properties of lysine-specific cysteine proteinase (Lys-gingipain) as a virulence factor of Porphyromonas gingivalis in periodontal diseaseQ46859545
Bacterial fimbriae activate human peripheral blood monocytes utilizing TLR2, CD14 and CD11a/CD18 as cellular receptorsQ64449475
Specific interactions between Porphyromonas gingivalis fimbriae and human extracellular matrix proteinsQ64449792
Identification of a molecule of Porphyromonas gingivalis that binds to Streptococcus gordoniiQ64450217
Involvement of Porphyromonas gingivalis fimbriae in adherence to Streptococcus gordoniiQ64450333
Genetic analyses of proteolysis, hemoglobin binding, and hemagglutination of Porphyromonas gingivalis. Construction of mutants with a combination of rgpA, rgpB, kgp, and hagAQ77863752
Characterization of proteinase-adhesin complexes of Porphyromonas gingivalisQ79930588
P433issue3
P407language of work or nameEnglishQ1860
P921main subjectperiodontologyQ938196
Porphyromonas gingivalisQ3214147
P304page(s)348-53
P577publication date2009-06-01
P1433published inJournal of Periodontal ResearchQ15759338
P1476titleGingipain enzymes from Porphyromonas gingivalis preferentially bind immobilized extracellular proteins: a mechanism favouring colonization?
P478volume44

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cites work (P2860)
Q34301436Cleavage of extracellular matrix in periodontitis: gingipains differentially affect cell adhesion activities of fibronectin and tenascin-C.
Q34076596Dichotomy of gingipains action as virulence factors: from cleaving substrates with the precision of a surgeon's knife to a meat chopper-like brutal degradation of proteins.
Q37374882Lysine gingipain (kgp) biovars of Porphyromonas gingivalis exhibit differential distribution on oral mucosal sites
Q43749260Meningococcal surface fibril (Msf) binds to activated vitronectin and inhibits the terminal complement pathway to increase serum resistance
Q35783075Porphyromonas gingivalis-derived RgpA-Kgp Complex Activates the Macrophage Urokinase Plasminogen Activator System: IMPLICATIONS FOR PERIODONTITIS
Q34746987Role of vimA in cell surface biogenesis in Porphyromonas gingivalis
Q46931083The autoantibody repertoire in periodontitis: a role in the induction of autoimmunity to citrullinated proteins in rheumatoid arthritis?
Q34152964Treponema denticola chymotrypsin-like proteinase (CTLP) integrates spirochaetes within oral microbial communities
Q28292158Vitronectin in bacterial pathogenesis: a host protein used in complement escape and cellular invasion

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