The hemoglobin receptor protein of porphyromonas gingivalis inhibits receptor activator NF-kappaB ligand-induced osteoclastogenesis from bone marrow macrophages

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The hemoglobin receptor protein of porphyromonas gingivalis inhibits receptor activator NF-kappaB ligand-induced osteoclastogenesis from bone marrow macrophages is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.1128/IAI.74.5.2544-2551.2006
P932PMC publication ID1459701
P698PubMed publication ID16622189

P50authorMariko NaitoQ114019319
P2093author name stringKoji Nakayama
Hitoshi Hotokezaka
Naoya Ohara
Noriaki Yoshida
Hideki Kitaura
Eiko Sakai
Yuka Narita
Yuji Fujimura
Mamiko Yoshimura
P2860cites workStimulation by toll-like receptors inhibits osteoclast differentiationQ24301850
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Osteoclast differentiation factor is a ligand for osteoprotegerin/osteoclastogenesis-inhibitory factor and is identical to TRANCE/RANKLQ24682139
OPGL is a key regulator of osteoclastogenesis, lymphocyte development and lymph-node organogenesisQ28589430
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A new member of tumor necrosis factor ligand family, ODF/OPGL/TRANCE/RANKL, regulates osteoclast differentiation and functionQ33542094
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Interleukin-18 (interferon-gamma-inducing factor) is produced by osteoblasts and acts via granulocyte/macrophage colony-stimulating factor and not via interferon-gamma to inhibit osteoclast formationQ36377004
Porphyromonas gingivalis induces receptor activator of NF-kappaB ligand expression in osteoblasts through the activator protein 1 pathwayQ36575882
The inhibitory effect of interleukin-10 on mouse osteoclast formation involves novel tyrosine-phosphorylated proteinsQ38312425
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Prostaglandin E(2) is a main mediator in receptor activator of nuclear factor-kappaB ligand-dependent osteoclastogenesis induced by Porphyromonas gingivalis, Treponema denticola, and Treponema socranskii.Q38514192
Effect of various factors on induction of liver tumors in animals by the alpha-isomer of benzene hexachlorideQ39337062
Bacterial fimbriae and their peptides activate human gingival epithelial cells through Toll-like receptor 2.Q39522825
Bacteroides gingivalis, Bacteroides intermedius and Actinobacillus actinomycetemcomitans in human periodontal diseasesQ39631665
Lipopolysaccharides from periodontopathic bacteria Porphyromonas gingivalis and Capnocytophaga ochracea are antagonists for human toll-like receptor 4.Q39653471
Porphyromonas gingivalis lipopolysaccharide is poorly recognized by molecular components of innate host defense in a mouse model of early inflammationQ39823660
Melatonin at pharmacologic doses increases bone mass by suppressing resorption through down-regulation of the RANKL-mediated osteoclast formation and activation.Q40720945
Mechanisms of alveolar bone destruction in periodontitis.Q41754991
Bifurcation of osteoclasts and dendritic cells from common progenitorsQ43757343
Molecular epidemiology and association of putative pathogens in root canal infectionQ44305135
Interleukin-7 is a direct inhibitor of in vitro osteoclastogenesisQ44514609
Serum antibodies against the hemoglobin-binding domain (HA2) of Porphyromonas gingivalisQ44944224
Intragingival occurrence of Actinobacillus actinomycetemcomitans and Bacteroides gingivalis in active destructive periodontal lesionsQ44952742
Autolysis of Porphyromonas gingivalis is accompanied by an increase in several periodontal pathogenic factors in the supernatantQ44991883
Osteoclast development in immobilized bone is suppressed by parathyroidectomy in miceQ45199769
Integrin activation by bacterial fimbriae through a pathway involving CD14, Toll-like receptor 2, and phosphatidylinositol-3-kinaseQ45288377
A model of periodontitis in the rat: effect of lipopolysaccharide on bone resorption, osteoclast activity, and local peptidergic innervationQ50098093
Local bone injections of LPS and M-CSF increase bone resorption by different pathways in vivo in rats.Q51670417
Inhibition of RANKL-induced osteoclast formation in mouse bone marrow cells by IL-12: involvement of IFN-γ possibly induced from non-T cell populationQ51813167
The natural history of periodontal disease in humans: risk factors for tooth loss in caries-free subjects receiving no oral health care.Q51966358
Effect of IL-12 on TNF-alpha-mediated osteoclast formation in bone marrow cells: apoptosis mediated by Fas/Fas ligand interaction.Q52113524
Construction and characterization of arginine-specific cysteine proteinase (Arg-gingipain)-deficient mutants of Porphyromonas gingivalis. Evidence for significant contribution of Arg-gingipain to virulence.Q52508036
Removal of endotoxin from recombinant protein preparations.Q54560669
RANKL maintains bone homeostasis through c-Fos-dependent induction of interferon-βQ57675150
Bone and haematopoietic defects in mice lacking c-fosQ58326969
Dual Modulation of Osteoclast Differentiation by LipopolysaccharideQ58456589
T-cell-mediated regulation of osteoclastogenesis by signalling cross-talk between RANKL and IFN-γQ59064307
Pleiotropic effects of a null mutation in the c-fos proto-oncogeneQ62555352
Endotoxin: Stimulation of Bone Resorption in Tissue CultureQ69905970
Bacterial invasion of periodontal tissues in advanced periodontitis in humansQ70961359
Effects of interleukin-4 on the formation of macrophages and osteoclast-like cellsQ72671386
Haemoglobin receptor protein is intragenically encoded by the cysteine proteinase-encoding genes and the haemagglutinin-encoding gene of Porphyromonas gingivalisQ74183899
A lipid A-associated protein of Porphyromonas gingivalis, derived from the haemagglutinating domain of the RI protease gene family, is a potent stimulator of interleukin 6 synthesisQ77659084
Genetic analyses of proteolysis, hemoglobin binding, and hemagglutination of Porphyromonas gingivalis. Construction of mutants with a combination of rgpA, rgpB, kgp, and hagAQ77863752
P433issue5
P407language of work or nameEnglishQ1860
P921main subjectNF-κBQ411114
Porphyromonas gingivalisQ3214147
P304page(s)2544-2551
P577publication date2006-05-01
P1433published inInfection and ImmunityQ6029193
P1476titleThe hemoglobin receptor protein of porphyromonas gingivalis inhibits receptor activator NF-kappaB ligand-induced osteoclastogenesis from bone marrow macrophages
P478volume74

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cites work (P2860)
Q54688248A challenge with Porphyromonas gingivalis differentially affects the osteoclastogenesis potential of periodontal ligament fibroblasts from periodontitis patients and non-periodontitis donors.
Q38176010Apoptosis-associated uncoupling of bone formation and resorption in osteomyelitis
Q49380410Bacterial modulators of bone remodeling in the periodontal pocket
Q40141904Differential Innate Immune Signaling in Macrophages by Wild-Type Vaccinia Mature Virus and a Mutant Virus with a Deletion of the A26 Protein
Q39344809Effects of Porphyromonas gingivalis surface-associated material on osteoclast formation
Q50054877Enterococcus faecalis immunoregulates osteoclastogenesis of macrophages
Q39078386Hemoglobin receptor protein from Porphyromonas gingivalis induces interleukin-8 production in human gingival epithelial cells through stimulation of the mitogen-activated protein kinase and NF-κB signal transduction pathways
Q33675274Metal uptake in host-pathogen interactions: role of iron in Porphyromonas gingivalis interactions with host organisms
Q47334710Molecular mechanisms of Porphyromonas gingivalis-host cell interaction on periodontal diseases
Q64265564Oral Mucosal Epithelial Cells
Q42816515Recombinant Porphyromonas gingivalis FimA preproprotein expressed in Escherichia coli is lipidated and the mature or processed recombinant FimA protein forms a short filament in vitro.

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