Gingipain-dependent interactions with the host are important for survival of Porphyromonas gingivalis

scientific article

Gingipain-dependent interactions with the host are important for survival of Porphyromonas gingivalis is …
instance of (P31):
scholarly articleQ13442814
review articleQ7318358

External links are
P356DOI10.2741/2922
P932PMC publication ID3403687
P698PubMed publication ID18508429

P2093author name stringCarlos A Casiano
Hansel M Fletcher
Shaun M Sheets
Antonette G Robles-Price
Rachelle M E McKenzie
P2860cites workIdentification of GRIM-19, a novel cell death-regulatory gene induced by the interferon-beta and retinoic acid combination, using a genetic approachQ22254731
Granzymes A and B directly cleave lamins and disrupt the nuclear lamina during granule-mediated cytolysisQ24291188
Granzyme A activates an endoplasmic reticulum-associated caspase-independent nuclease to induce single-stranded DNA nicksQ24291688
GRIM-19 interacts with nucleotide oligomerization domain 2 and serves as downstream effector of anti-bacterial function in intestinal epithelial cellsQ24297555
Cleaving the oxidative repair protein Ape1 enhances cell death mediated by granzyme AQ24338600
Caspases: the executioners of apoptosisQ24530218
Intrinsic apoptotic pathways of gingival epithelial cells modulated by Porphyromonas gingivalisQ24633584
Disruption of epithelial cell-matrix interactions induces apoptosisQ24673611
Complete genome sequence of the oral pathogenic Bacterium porphyromonas gingivalis strain W83Q24682539
Role of oxidants in microbial pathophysiologyQ24683780
Tumor suppressor NM23-H1 is a granzyme A-activated DNase during CTL-mediated apoptosis, and the nucleosome assembly protein SET is its inhibitorQ28182042
Anoikis mechanismsQ28215553
Butyric acid-induced T-cell apoptosis is mediated by caspase-8 and -9 activation in a Fas-independent mannerQ28359805
Thioredoxin-dependent hydroperoxide peroxidase activity of bacterioferritin comigratory protein (BCP) as a new member of the thiol-specific antioxidant protein (TSA)/Alkyl hydroperoxide peroxidase C (AhpC) familyQ28369099
Caspases: enemies withinQ29547315
Biological roles of oligosaccharides: all of the theories are correctQ29616459
Repair of oxidative damage to DNA: enzymology and biologyQ29618065
Caspase and bid involvement in Clostridium difficile toxin A-induced apoptosis and modulation of toxin A effects by glutamine and alanyl-glutamine in vivo and in vitroQ30439015
Emerging strategies in microbial haem capture.Q30636480
Damage recognition in nucleotide excision repair of DNA.Q30839135
Pleiotropic pigmentation mutants of Porphyromonas gingivalisQ30857715
Induction of rapid histone degradation by the cytotoxic T lymphocyte protease Granzyme A.Q31520093
Acquisition of iron from human transferrin by Porphyromonas gingivalis: a role for Arg- and Lys-gingipain activitiesQ32155652
Expression of Arg-Gingipain RgpB is required for correct glycosylation and stability of monomeric Arg-gingipain RgpA from Porphyromonas gingivalis W50.Q33220254
The regulation of apoptosis by microbial pathogens.Q33599759
Chronic Helicobacter pylori infection induces an apoptosis-resistant phenotype associated with decreased expression of p27(kip1)Q33600141
Base excision repair of 8-hydroxyguanine protects DNA from endogenous oxidative stressQ33601035
Oxidative stressQ33632507
Apoptosis without caspases: an inefficient molecular guillotine?Q33669485
Cellular adhesion molecules and atherogenesisQ33686005
Gingipains from Porphyromonas gingivalis W83 induce cell adhesion molecule cleavage and apoptosis in endothelial cellsQ33716013
Altered gingipain maturation in vimA- and vimE-defective isogenic mutants of Porphyromonas gingivalisQ33716035
Nitric oxide: a potential inducer of adhesion-related apoptosis--anoikisQ35721576
Programmed cell deaths. Apoptosis and alternative deathstylesQ35750745
Morphological features of cell deathQ35773151
Signalling mechanisms of anoikisQ35787408
Persistent bacterial infections: the interface of the pathogen and the host immune systemQ35889600
Regulation of integrin functions by N-glycansQ35910283
Iron and heme utilization in Porphyromonas gingivalis.Q36010834
Protein glycosylation in bacterial mucosal pathogensQ36058412
The role of host cell death in Salmonella infections.Q36080758
Apoptosis and its modulation during infection with Toxoplasma gondii: molecular mechanisms and role in pathogenesis.Q36080769
Porphyromonas gingivalis, Treponema denticola, and Tannerella forsythia: the "red complex", a prototype polybacterial pathogenic consortium in periodontitisQ36107786
Environmental signals controlling expression of virulence determinants in bacteriaQ36109256
Integrins as a distinct subtype of dependence receptorsQ36149589
Reactive oxygen species and human inflammatory periodontal diseasesQ36204473
Extracellular matrix survival signals transduced by focal adhesion kinase suppress p53-mediated apoptosis.Q36255622
Clinging to life: cell to matrix adhesion and cell survivalQ36301231
Porphyromonas gingivalis-epithelial cell interactions in periodontitisQ36457270
Recognition and repair of compound DNA lesions (base damage and mismatch) by human mismatch repair and excision repair systemsQ36565271
Periodontal disease and systemic conditions: a bidirectional relationship.Q36602669
Periodontal infections and cardiovascular disease: the heart of the matter.Q36609001
Inhibition of anchorage-dependent cell spreading triggers apoptosis in cultured human endothelial cellsQ36676242
The role of reactive oxygen and antioxidant species in periodontal tissue destructionQ36703964
Isolation, expression, and nucleotide sequence of the sod gene from Porphyromonas gingivalisQ36962541
The vimE gene downstream of vimA is independently expressed and is involved in modulating proteolytic activity in Porphyromonas gingivalis W83.Q37522801
8-oxo-7,8-dihydroguanine is removed by a nucleotide excision repair-like mechanism in Porphyromonas gingivalis W83.Q37596229
The molecular biology of apoptosisQ37688810
Distinct transcriptional profiles characterize oral epithelium-microbiota interactionsQ38520459
Secretion, processing and activation of bacterial extracellular proteasesQ38766392
Hemoglobinase activity of the lysine gingipain protease (Kgp) of Porphyromonas gingivalis W83.Q39496808
Targeted disruption of fibronectin-integrin interactions in human gingival fibroblasts by the RI protease of Porphyromonas gingivalis W50.Q39510504
Effect of temperature on growth, hemagglutination, and protease activity of Porphyromonas gingivalisQ39510560
Characterization of Porphyromonas gingivalis-induced degradation of epithelial cell junctional complexesQ39514636
Regulation of the Porphyromonas gingivalis fimA (Fimbrillin) geneQ39517061
Role of oxyR in the oral anaerobe Porphyromonas gingivalisQ34514368
Temporal activation of anti- and pro-apoptotic factors in human gingival fibroblasts infected with the periodontal pathogen, Porphyromonas gingivalis: potential role of bacterial proteases in host signallingQ34521878
Repair of oxidative DNA damage: mechanisms and functionsQ34562458
Molecular mechanisms of "detachment-induced apoptosis--Anoikis".Q34629157
Triggering caspase-independent cell death to combat cancer.Q34688272
How oxygen damages microbes: oxygen tolerance and obligate anaerobiosisQ34695118
A novel repair enzyme: UVRABC excision nuclease of Escherichia coli cuts a DNA strand on both sides of the damaged regionQ34708982
Role of Porphyromonas gingivalis FeoB2 in metal uptake and oxidative stress protectionQ34721202
Activation of the phosphatidylinositol 3-kinase/Akt pathway contributes to survival of primary epithelial cells infected with the periodontal pathogen Porphyromonas gingivalisQ34758757
Microbial/host interactions: mechanisms involved in host responses to microbial antigensQ34981933
Apoptotic pathways: involvement of lysosomal proteasesQ35000696
Oxidative nucleotide damage: consequences and preventionQ35026366
Enzymology of the repair of free radicals-induced DNA damageQ35026369
Oxy radicals, lipid peroxidation and DNA damageQ35035506
Programmed cell death: many ways for cells to die decently.Q35043428
The role of gingipains in the pathogenesis of periodontal diseaseQ35068830
Gingipains from Porphyromonas gingivalis W83 synergistically disrupt endothelial cell adhesion and can induce caspase-independent apoptosisQ35073929
The RgpB C-terminal domain has a role in attachment of RgpB to the outer membrane and belongs to a novel C-terminal-domain family found in Porphyromonas gingivalisQ35075282
Many cuts to ruin: a comprehensive update of caspase substratesQ35091412
Proteolytic and hydrolytic enzymes from putative periodontal pathogens: characterization, molecular genetics, effects on host defenses and tissues and detection in gingival crevice fluidQ35092090
Bacterial glycoproteins: functions, biosynthesis and applicationsQ35104114
Gingipain RgpB is excreted as a proenzyme in the vimA-defective mutant Porphyromonas gingivalis FLL92.Q35106177
Anoikis in the cardiovascular system: known and unknown extracellular mediatorsQ35556526
Nucleotide sequence of the Porphyromonas gingivalis W83 recA homolog and construction of a recA-deficient mutantQ35557864
Caspases: an ancient cellular sword of DamoclesQ35597035
Molecular genetics of Porphyromonas gingivalis: gingipains and other virulence factorsQ35610523
Gingipains, the major cysteine proteinases and virulence factors of Porphyromonas gingivalis: structure, function and assembly of multidomain protein complexesQ35610528
Glycosylation of the Arg-gingipains of Porphyromonas gingivalis and comparison with glycoconjugate structure and synthesis in other bacteriaQ35610535
Heat shock proteins in the regulation of apoptosis: new strategies in tumor therapy: a comprehensive reviewQ35697057
Inactivation of membrane tumor necrosis factor alpha by gingipains from Porphyromonas gingivalisQ33716115
Virulence factors of Porphyromonas gingivalis.Q33752051
Volatile fatty acid, metabolic by-product of periodontopathic bacteria, induces apoptosis in WEHI 231 and RAJI B lymphoma cells and splenic B cells.Q33754406
Contact-dependent protein secretion in Porphyromonas gingivalisQ33765304
The induction of apoptosis by bacterial pathogensQ33765932
Gene expression in Porphyromonas gingivalis after contact with human epithelial cellsQ33769338
Molecular genetics and nomenclature of proteases of Porphyromonas gingivalisQ33852051
Temperature-regulated expression of bacterial virulence genesQ33878638
Inactivation of vimF, a putative glycosyltransferase gene downstream of vimE, alters glycosylation and activation of the gingipains in Porphyromonas gingivalis W83.Q33883348
The modulation of host cell apoptosis by intracellular bacterial pathogensQ33957483
Protective role of catalase in Pseudomonas aeruginosa biofilm resistance to hydrogen peroxide.Q33985805
An iron-regulated alkyl hydroperoxide reductase (AhpC) confers aerotolerance and oxidative stress resistance to the microaerophilic pathogen Campylobacter jejuniQ33992668
Binding specificity of the Porphyromonas gingivalis heme and hemoglobin receptor HmuR, gingipain K, and gingipain R1 for heme, porphyrins, and metalloporphyrinsQ33996913
Alkyl hydroperoxide reductase is the primary scavenger of endogenous hydrogen peroxide in Escherichia coliQ33997228
Variable carbohydrate modifications to the catalytic chains of the RgpA and RgpB proteases of Porphyromonas gingivalis W50.Q34001332
vimA gene downstream of recA is involved in virulence modulation in Porphyromonas gingivalis W83.Q34005626
The nucleotide excision repair protein UvrB, a helicase-like enzyme with a catch.Q34006354
Porphyromonas gingivalis fimbria-dependent activation of inflammatory genes in human aortic endothelial cells.Q34034262
Noncaspase proteases in apoptosisQ34037785
Fimbria-dependent activation of cell adhesion molecule expression in Porphyromonas gingivalis-infected endothelial cellsQ34116111
Hijacking of apoptotic pathwaysby bacterial pathogensQ34117471
Role of rubrerythrin in the oxidative stress response of Porphyromonas gingivalisQ34125205
Porphyromonas gingivalis RgpA and Kgp proteinases and adhesins are C terminally processed by the carboxypeptidase CPG70.Q34143471
Characterization of a unique glycosylated anchor endopeptidase that cleaves the LPXTG sequence motif of cell surface proteins of Gram-positive bacteriaQ34153505
DNA damage and oxygen radical toxicityQ34172435
Role of bacterial proteinases in matrix destruction and modulation of host responsesQ34200755
The HtrA (DegP) protein, essential for Escherichia coli survival at high temperatures, is an endopeptidaseQ34205435
Environmental cues and gene expression in Porphyromonas gingivalis and Actinobacillus actinomycetemcomitans.Q34252429
Molecular cloning and structural characterization of the Arg-gingipain proteinase of Porphyromonas gingivalis. Biosynthesis as a proteinase-adhesin polyproteinQ34317271
Four deaths and a funeral: from caspases to alternative mechanisms.Q34325335
Molecular mechanisms of bacteria induced apoptosis.Q34398419
THE DISAPPEARANCE OF THYMINE DIMERS FROM DNA: AN ERROR-CORRECTING MECHANISMQ34398677
The HtrA family of serine proteasesQ34447737
Gingipains of Porphyromonas gingivalis modulate leukocyte adhesion molecule expression induced in human endothelial cells by ligation of CD99.Q34491722
Identification of apoptosis-inducing factor in human coronary artery endothelial cellsQ44283221
Hemoglobin hydrolysis and heme acquisition by Porphyromonas gingivalisQ44695410
The effect of oxygen on the growth and physiology of Porphyromonas gingivalisQ44761512
Studies on NADH oxidase and alkyl hydroperoxide reductase produced by Porphyromonas gingivalis.Q44858773
Alkyl hydroperoxide peroxidase subunit C (ahpC) protects against organic peroxides but does not affect the virulence of Porphyromonas gingivalis W83.Q44946525
The C-terminal domains of the gingipain K polyprotein are necessary for assembly of the active enzyme and expression of associated activitiesQ45156919
Molecular cloning and characterization of Porphyromonas gingivalis lysine-specific gingipain. A new member of an emerging family of pathogenic bacterial cysteine proteinasesQ46086294
Lactoferrin-enhanced anoikis: a defense against neonatal necrotizing enterocolitis.Q46346997
Intrinsic pathway of hydroquinone induced apoptosis occurs via both caspase-dependent and caspase-independent mechanismsQ46389392
Detection of periodontopathic bacteria and an oxidative stress marker in saliva from periodontitis patientsQ46534745
Differential display analysis of Porphyromonas gingivalis gene activation response to heat and oxidative stressQ46534753
Functional dissociation of DeltaPsim and cytochrome c release defines the contribution of mitochondria upstream of caspase activation during granzyme B-induced apoptosisQ46706728
Porphyromonas gingivalis-related cardiac cell apoptosis was majorly co-activated by p38 and extracellular signal-regulated kinase pathwaysQ46892099
Porphyromonas gingivalis enhances FasL expression via up-regulation of NFkappaB-mediated gene transcription and induces apoptotic cell death in human gingival epithelial cellsQ46973398
Cleavage of p130Cas in anoikisQ47242527
Characterization of the proteinase-dependent cytotoxicity of Porphyromonas gingivalisQ47671159
Hemoglobin-binding protein purified from Porphyromonas gingivalis is identical to lysine-specific cysteine proteinase (Lys-gingipain).Q47680541
Involvement of a lysine-specific cysteine proteinase in hemoglobin adsorption and heme accumulation by Porphyromonas gingivalisQ47724105
Genetic variation of Porphyromonas gingivalis genes encoding gingipains, cysteine proteinases with arginine or lysine specificityQ48039254
A cell-associated protein complex of Porphyromonas gingivalis W50 composed of Arg- and Lys-specific cysteine proteinases and adhesinsQ48047767
Domain-specific rearrangement between the two Arg-gingipain-encoding genes in Porphyromonas gingivalis: possible involvement of nonreciprocal recombinationQ48055797
Novel stationary-phase-upregulated protein of Porphyromonas gingivalis influences production of superoxide dismutase, thiol peroxidase and thioredoxinQ48147411
Spontaneous mutation, oxidative DNA damage, and the roles of base and nucleotide excision repair in the yeast Saccharomyces cerevisiaeQ50519819
Induction of apoptosis in human gingival fibroblasts by a Porphyromonas gingivalis protease preparation.Q53940500
HtrA is the unique surface housekeeping protease in Lactococcus lactis and is required for natural protein processingQ60529736
Interaction of Porphyromonas gingivalis with KB cells: comparison of different clinical isolatesQ64449483
Effect of cysteine protease of Porphyromonas gingivalis on adhesion molecules in gingival epithelial cellsQ64449775
Cytotoxicity of Porphyromonas gingivalis toward cultured human gingival fibroblastsQ64450353
Superoxide dismutase, catalase and peroxidases in oral anaerobic bacteriaQ68754639
Binding of hemoglobin by Porphyromonas gingivalisQ70983898
Mechanism of oxidative DNA damage induction in a strict anaerobe, Prevotella melaninogenicaQ73098903
Caspase inhibition prevents the mitochondrial release of apoptosis-inducing factorQ73549292
Efficient repair of hydrogen peroxide-induced DNA damage by Escherichia coli requires SOS induction of RecA and RuvA proteinsQ73795289
Proteolysis of human monocyte CD14 by cysteine proteinases (gingipains) from Porphyromonas gingivalis leading to lipopolysaccharide hyporesponsivenessQ73910774
Molecular mediators of Porphyromonas gingivalis-induced T-cell apoptosisQ74471218
Iron protoporphyrin IX-albumin complexing increases the capacity and avidity of its binding to the periodontopathogen Porphyromonas gingivalisQ74629295
Tumor necrosis factor modulates fibroblast apoptosis, PMN recruitment, and osteoclast formation in response to P. gingivalis infectionQ77165208
In vitro studies of lymphocyte apoptosis induced by the periodontal pathogen Porphyromonas gingivalisQ77338494
Genetic analyses of proteolysis, hemoglobin binding, and hemagglutination of Porphyromonas gingivalis. Construction of mutants with a combination of rgpA, rgpB, kgp, and hagAQ77863752
Granzyme A loading induces rapid cytolysis and a novel form of DNA damage independently of caspase activationQ77879079
VimA is part of the maturation pathway for the major gingipains of Porphyromonas gingivalis W83Q79317261
HtrA in Porphyromonas gingivalis can regulate growth and gingipain activity under stressful environmental conditionsQ79317263
Monitoring of dnaK gene expression in Porphyromonas gingivalis by oxygen stress using DNA microarrayQ80404856
Proteomics-based analysis of a counter-oxidative stress system in Porphyromonas gingivalisQ81466177
Superoxide dismutase-encoding gene of the obligate anaerobe Porphyromonas gingivalis is regulated by the redox-sensing transcription activator OxyRQ82891253
The HA2 haemagglutinin domain of the lysine-specific gingipain (Kgp) of Porphyromonas gingivalis promotes micro-oxo bishaem formation from monomeric iron(III) protoporphyrin IXQ83877834
???Q24530651
Interleukin-8 and intercellular adhesion molecule 1 regulation in oral epithelial cells by selected periodontal bacteria: multiple effects of Porphyromonas gingivalis via antagonistic mechanismsQ39518638
Porphyromonas gingivalis gingipains and adhesion to epithelial cellsQ39519857
Porphyromonas gingivalis fimbriae inhibit caspase-3-mediated apoptosis of monocytic THP-1 cells under growth factor deprivation via extracellular signal-regulated kinase-dependent expression of p21 Cip/WAF1.Q39521503
Association of mitogen-activated protein kinase pathways with gingival epithelial cell responses to Porphyromonas gingivalis infectionQ39529442
Role of superoxide dismutase activity in the physiology of Porphyromonas gingivalis.Q39612964
Campylobacter protein glycosylation affects host cell interactionsQ39654628
Hydrolysis of epithelial junctional proteins by Porphyromonas gingivalis gingipainsQ39654845
Nuclear targeting of Porphyromonas gingivalis W50 protease in epithelial cellsQ39656418
Discrete proteolysis of focal contact and adherens junction components in Porphyromonas gingivalis-infected oral keratinocytes: a strategy for cell adhesion and migration disabling.Q39656552
Calcium oscillations in gingival epithelial cells infected with Porphyromonas gingivalisQ39683212
Purification, gene cloning, gene expression, and mutants of Dps from the obligate anaerobe Porphyromonas gingivalisQ39730048
In vivo induction of apoptosis and immune responses in mice by administration of lipopolysaccharide from Porphyromonas gingivalisQ39824769
Involvement of arginine-specific cysteine proteinase (Arg-gingipain) in fimbriation of Porphyromonas gingivalisQ39841339
Porphyromonas gingivalis strain-dependent activation of human endothelial cellsQ40016880
Role of superoxide dismutase in resistance of Porphyromonas gingivalis to killing by polymorphonuclear leukocytesQ40149421
The role of oxygen and its derivatives in microbial pathogenesis and host defenseQ40191358
The extracellular matrix as a cell survival factorQ40241699
Anti-apoptotic N-cadherin signaling and its prognostic implication in human hepatocellular carcinomas.Q40295652
Role of calcineurin in Porphyromonas gingivalis-induced myocardial cell hypertrophy and apoptosisQ40337512
Jararhagin, a snake venom metalloproteinase, induces a specialized form of apoptosis (anoikis) selective to endothelial cellsQ40379408
Involvement of lysosomal cathepsins in the cleavage of DNA topoisomerase I during necrotic cell deathQ40403781
Lipopolysaccharide from the periodontal pathogen Porphyromonas gingivalis prevents apoptosis of HL60-derived neutrophils in vitroQ40403822
Repair of DNA containing the oxidatively-damaged base, 8-oxoguanineQ40486514
Role of glycosylphosphatidylinositols in the activation of phospholipase A2 and the neurotoxicity of prionsQ40489236
Gingipain adhesin domains mediate Porphyromonas gingivalis adherence to epithelial cellsQ40582349
Proteolysis of ICAM-1 on Human Oral Epithelial Cells by GingipainsQ40630742
Serine proteases mediate apoptosis-like cell death and phagocytosis under caspase-inhibiting conditions.Q40632735
Arg-gingipain is responsible for the degradation of cell adhesion molecules of human gingival fibroblasts and their death induced by Porphyromonas gingivalisQ40784513
Role of free radicals and antioxidants in the pathogenesis of the inflammatory periodontal diseasesQ40849481
Mutagenesis by 8-oxoguanine: an enemy withinQ40849891
Apoptosis in Porphyromonas gingivalis-specific T-cell linesQ40868434
Involvement of FADD and caspase-8 signalling in detachment-induced apoptosisQ40925076
Regulation of matrix metalloproteinases during extracellular matrix turnover.Q40951726
Porphyromonas gingivalis: a proteinase/gene accounting auditQ40953479
A role for Jun-N-terminal kinase in anoikis; suppression by bcl-2 and crmA.Q41149112
In vitro models of tissue penetration and destruction by Porphyromonas gingivalisQ41195310
DNA glycosylases in the base excision repair of DNAQ41532551
Glycoproteins in prokaryotesQ41650848
Assessment of the Relative Cytotoxicity of Porphyromonas gingivalis Cells, Products, and Components on Human Epithelial Cell LinesQ41651177
Intercellular spreading of Porphyromonas gingivalis infection in primary gingival epithelial cellsQ41859338
The periodontopathogen Porphyromonas gingivalis binds iron protoporphyrin IX in the mu-oxo dimeric form: an oxidative buffer and possible pathogenic mechanismQ42115902
Construction and characterization of a nonpigmented mutant of Porphyromonas gingivalis: cell surface polysaccharide as an anchorage for gingipainsQ42673712
Does the importance of the C-terminal residues in the maturation of RgpB from Porphyromonas gingivalis reveal a novel mechanism for protein export in a subgroup of Gram-Negative bacteria?Q42957420
Environmental regulation of recA gene expression in Porphyromonas gingivalisQ43169399
Association between epithelial cell death and invasion by microspheres conjugated to Porphyromonas gingivalis vesicles with different types of fimbriaeQ43181650
Identification of proteins differentially expressed in human monocytes exposed to Porphyromonas gingivalis and its purified components by high-throughput immunoblottingQ43197057
Protease-active extracellular protein preparations from Porphyromonas gingivalis W83 induce N-cadherin proteolysis, loss of cell adhesion, and apoptosis in human epithelial cellsQ43631259
Inhibition of epithelial cell apoptosis by Porphyromonas gingivalisQ43652933
The recA gene in Porphyromonas gingivalis is expressed during infection of the murine hostQ43666245
Two distinct mechanisms for induction of dendritic cell apoptosis in response to intact Streptococcus pneumoniaeQ43702131
Crystallization and preliminary X-ray studies of the protease domain of the heat-shock protein HtrA from Thermotoga maritima.Q43830439
Carbohydrate moieties on the procofactor factor V, but not the derived cofactor factor Va, regulate its inactivation by activated protein C.Q43868495
The periodontal pathogen Porphyromonas gingivalis harnesses the chemistry of the mu-oxo bishaem of iron protoporphyrin IX to protect against hydrogen peroxide.Q43896377
Roles for Arg- and Lys-gingipains in the disruption of cytokine responses and loss of viability of human endothelial cells by Porphyromonas gingivalis infectionQ44219911
Death of HT29 adenocarcinoma cells induced by TNF family receptor activation is caspase-independent and displays features of both apoptosis and necrosisQ44246409
Sequential autolytic processing activates the zymogen of Arg-gingipainQ44281862
P407language of work or nameEnglishQ1860
P921main subjectPorphyromonas gingivalisQ3214147
P304page(s)3215-38
P577publication date2008-01-01
P1433published inFrontiers in BioscienceQ5506062
P1476titleGingipain-dependent interactions with the host are important for survival of Porphyromonas gingivalis
P478volume13

Reverse relations

cites work (P2860)
Q34205609A Computational Simulation Study of Benzamidine Derivatives Binding to Arginine-Specific Gingipain (HRgpA) from Periodontopathogen Porphyromonas gingivalis
Q34057081Abrogation of neuraminidase reduces biofilm formation, capsule biosynthesis, and virulence of Porphyromonas gingivalis
Q34270695Antibacterial effect of crude extract and metabolites of Phytolacca americana on pathogens responsible for periodontal inflammatory diseases and dental caries
Q39771727Bacteria-derived hydrogen sulfide promotes IL-8 production from epithelial cells.
Q36824616Bacterial invasion of epithelial cells and spreading in periodontal tissue
Q38188864Bacterial proteases: targets for diagnostics and therapy.
Q87083143Bactericidal effect of extracts and metabolites of Robinia pseudoacacia L. on Streptococcus mutans and Porphyromonas gingivalis causing dental plaque and periodontal inflammatory diseases
Q37586359Breaking bad: manipulation of the host response by Porphyromonas gingivalis.
Q35003110Corruption of innate immunity by bacterial proteases
Q41460026Crystallization and preliminary X-ray crystallographic studies of dipeptidyl peptidase 11 from Porphyromonas gingivalis.
Q34999051Deletion of lipoprotein PG0717 in Porphyromonas gingivalis W83 reduces gingipain activity and alters trafficking in and response by host cells
Q34076596Dichotomy of gingipains action as virulence factors: from cleaving substrates with the precision of a surgeon's knife to a meat chopper-like brutal degradation of proteins.
Q92513828Effect of deletion of the rgpA gene on selected virulence of Porphyromonas gingivalis
Q93178443Exosomes on the border of species and kingdom intercommunication
Q37254826Genetic diversity in the oral pathogen Porphyromonas gingivalis: molecular mechanisms and biological consequences.
Q33883353Genetic transformation of an obligate anaerobe, P. gingivalis for FMN-green fluorescent protein expression in studying host-microbe interaction.
Q37704954Human neutrophils and oral microbiota: a constant tug-of-war between a harmonious and a discordant coexistence
Q27333995Identification and characterization of fusolisin, the Fusobacterium nucleatum autotransporter serine protease
Q35596229Immune evasion strategies of Porphyromonas gingivalis.
Q38212673Immuno-pathogenesis of Periodontal Disease: Current and Emerging Paradigms
Q34744022In Porphyromonas gingivalis VimF is involved in gingipain maturation through the transfer of galactose
Q34593465Involvement of PG2212 zinc finger protein in the regulation of oxidative stress resistance in Porphyromonas gingivalis W83
Q42385791Involvement of extracytoplasmic function sigma factors in virulence regulation in Porphyromonas gingivalis W83
Q55407560Localization and density of Porphyromonas gingivalis and Tannerella forsythia in gingival and subgingival granulation tissues affected by chronic or aggressive periodontitis.
Q47334710Molecular mechanisms of Porphyromonas gingivalis-host cell interaction on periodontal diseases
Q33681822Necrotrophic growth of periodontopathogens is a novel virulence factor in oral biofilms
Q61453151Outer Membrane Vesicle-Host Cell Interactions
Q27001535Oxidative stress resistance in Porphyromonas gingivalis
Q35830530Periodontal disease and rheumatoid arthritis: the evidence accumulates for complex pathobiologic interactions
Q30844783Porphyromonas gingivalis gingipains cause defective macrophage migration towards apoptotic cells and inhibit phagocytosis of primary apoptotic neutrophils.
Q40714188Porphyromonas gingivalis, a periodontal pathogen, enhances myocardial vulnerability, thereby promoting post-infarct cardiac rupture
Q24655246Porphyromonas gingivalis-host interactions: open war or intelligent guerilla tactics?
Q40075939Preventive effects of the novel antimicrobial peptide Nal-P-113 in a rat Periodontitis model by limiting the growth of Porphyromonas gingivalis and modulating IL-1β and TNF-α production
Q28535433Protective role of the PG1036-PG1037-PG1038 operon in oxidative stress in Porphyromonas gingivalis W83
Q101038893Quercetin inhibits virulence properties of Porphyromas gingivalis in periodontal disease
Q36527543Regulon controlled by the GppX hybrid two component system in Porphyromonas gingivalis
Q42954407Scavenger receptor A is expressed by macrophages in response to Porphyromonas gingivalis, and participates in TNF-alpha expression
Q43071859Structural analysis of the core region of O-lipopolysaccharide of Porphyromonas gingivalis from mutants defective in O-antigen ligase and O-antigen polymerase.
Q37285445The chronicles of Porphyromonas gingivalis: the microbium, the human oral epithelium and their interplay.
Q42266216The diagnostic potential of salivary protease activities in periodontal health and disease
Q37470595The gingipains: scissors and glue of the periodontal pathogen, Porphyromonas gingivalis
Q43683133The role of Porphyromonas gingivalis gingipains in platelet activation and innate immune modulation
Q41337922The role of phagocytosis, oxidative burst and neutrophil extracellular traps in the interaction between neutrophils and the periodontal pathogen Porphyromonas gingivalis
Q38070935VimA mediates multiple functions that control virulence in Porphyromonas gingivalis

Search more.