Breaking bad: manipulation of the host response by Porphyromonas gingivalis.

scientific article published on February 2014

Breaking bad: manipulation of the host response by Porphyromonas gingivalis. is …
instance of (P31):
scholarly articleQ13442814

External links are
P356DOI10.1002/EJI.201344202
P932PMC publication ID3925422
P698PubMed publication ID24338806

P50authorRichard LamontQ89232703
George HajishengallisQ39672238
P2860cites workPorphyromonas gingivalis facilitates the development and progression of destructive arthritis through its unique bacterial peptidylarginine deiminase (PAD)Q21089593
Low-abundance biofilm species orchestrates inflammatory periodontal disease through the commensal microbiota and complementQ24594632
Porphyromonas gingivalis as a potential community activist for diseaseQ24616806
The C5a receptor impairs IL-12-dependent clearance of Porphyromonas gingivalis and is required for induction of periodontal bone lossQ24618908
Gingipain-dependent interactions with the host are important for survival of Porphyromonas gingivalisQ24630104
Intrinsic apoptotic pathways of gingival epithelial cells modulated by Porphyromonas gingivalisQ24633584
P. gingivalis accelerates gingival epithelial cell progression through the cell cycleQ24650372
Porphyromonas gingivalis-host interactions: open war or intelligent guerilla tactics?Q24655246
Porphyromonas gingivalis: an invasive and evasive opportunistic oral pathogenQ27002394
Tyrosine phosphorylation and bacterial virulenceQ27009174
Microbial manipulation of receptor crosstalk in innate immunityQ30499616
Identification of a second lipopolysaccharide in Porphyromonas gingivalis W50Q33319075
Efficacy of antibiotics against periodontopathogenic bacteria within epithelial cells: an in vitro studyQ45162034
Integrin activation by bacterial fimbriae through a pathway involving CD14, Toll-like receptor 2, and phosphatidylinositol-3-kinaseQ45288377
Activation of complement components C3 and C5 by a cysteine proteinase (gingipain-1) from Porphyromonas (Bacteroides) gingivalis.Q46312320
Fimbrial proteins of porphyromonas gingivalis mediate in vivo virulence and exploit TLR2 and complement receptor 3 to persist in macrophages.Q54476982
'Blooming' in the gut: how dysbiosis might contribute to pathogen evolutionQ63968591
Gingival epithelial cell signalling and cytoskeletal responses to Porphyromonas gingivalis invasionQ64449425
Persistence of extracrevicular bacterial reservoirs after treatment of aggressive periodontitis.Q64943983
Cutting Edge: TLR2 is required for the innate response to Porphyromonas gingivalis: activation leads to bacterial persistence and TLR2 deficiency attenuates induced alveolar bone resorptionQ79401044
The quorum-sensing molecule N-3-oxododecanoyl homoserine lactone (3OC12-HSL) enhances the host defence by activating human polymorphonuclear neutrophils (PMN)Q80102959
Biphasic effect of gingipains from Porphyromonas gingivalis on the human complement systemQ80358557
Phagocytosis of staphylococci biofilms by polymorphonuclear neutrophils: S. aureus and S. epidermidis differ with regard to their susceptibility towards the host defenseQ84781883
Destruction of Bacterial Biofilms by Polymorphonuclear Neutrophils: Relative contribution of Phagocytosis, DNA Release, and DegranulationQ85125504
Immune defense against S. epidermidis biofilms: components of the extracellular polymeric substance activate distinct bactericidal mechanisms of phagocytic cellsQ87443896
Ability of bacteria associated with chronic inflammatory disease to stimulate E-selectin expression and promote neutrophil adhesionQ39821679
Differential interactions of fimbriae and lipopolysaccharide from Porphyromonas gingivalis with the Toll-like receptor 2-centred pattern recognition apparatusQ40230062
TLR2 transmodulates monocyte adhesion and transmigration via Rac1- and PI3K-mediated inside-out signaling in response to Porphyromonas gingivalis fimbriaeQ40271727
Actinobacillus actinomycetemcomitans, Porphyromonas gingivalis, and Tannerella forsythensis are components of a polymicrobial intracellular flora within human buccal cells.Q40459069
Complement factor D̄-like activity of Porphyromonas gingivalis W83Q41132518
Porphyromonas gingivalis infection sequesters pro-apoptotic Bad through Akt in primary gingival epithelial cellsQ41577708
The gingival tissues: the architecture of periodontal protectionQ41754677
ATP-dependent activation of an inflammasome in primary gingival epithelial cells infected by Porphyromonas gingivalisQ41818799
A Porphyromonas gingivalis tyrosine phosphatase is a multifunctional regulator of virulence attributesQ41828590
Intercellular spreading of Porphyromonas gingivalis infection in primary gingival epithelial cellsQ41859338
Porphyromonas gingivalis SerB-mediated dephosphorylation of host cell cofilin modulates invasion efficiencyQ41982299
Human Toll-like receptor 4 responses to P. gingivalis are regulated by lipid A 1- and 4'-phosphatase activitiesQ42714693
Microbial hijacking of complement-toll-like receptor crosstalkQ42911622
Periodontitis in RA-the citrullinated enolase connection.Q42916208
ATP scavenging by the intracellular pathogen Porphyromonas gingivalis inhibits P2X7-mediated host-cell apoptosis.Q43185488
Complement receptor 3 blockade promotes IL-12-mediated clearance of Porphyromonas gingivalis and negates its virulence in vivoQ43985683
Involvement of integrins in fimbriae-mediated binding and invasion by Porphyromonas gingivalis.Q44004516
C5a negatively regulates toll-like receptor 4-induced immune responsesQ44924554
Host defence against Staphylococcus aureus biofilms infection: phagocytosis of biofilms by polymorphonuclear neutrophils (PMN).Q33414914
Proteomics of Porphyromonas gingivalis within a model oral microbial communityQ33447901
Pathway analysis for intracellular Porphyromonas gingivalis using a strain ATCC 33277 specific databaseQ33499084
Neutrophil fate in gingival crevicular fluidQ33523593
Temperature-dependent modulation of Porphyromonas gingivalis lipid A structure and interaction with the innate host defenses.Q33789766
Epithelial cell pro-inflammatory cytokine response differs across dental plaque bacterial speciesQ33975334
Dichotomy of gingipains action as virulence factors: from cleaving substrates with the precision of a surgeon's knife to a meat chopper-like brutal degradation of proteins.Q34076596
Periodontal innate immune mechanisms relevant to atherosclerosis and obesityQ34083329
The human oral microbiomeQ34127792
Review: Pathogen-induced inflammation at sites distant from oral infection: bacterial persistence and induction of cell-specific innate immune inflammatory pathways.Q34181823
Role of Porphyromonas gingivalis phosphoserine phosphatase enzyme SerB in inflammation, immune response, and induction of alveolar bone resorption in ratsQ34290681
The keystone-pathogen hypothesis.Q34297138
Pathogen-mediated proteolysis of the cell death regulator RIPK1 and the host defense modulator RIPK2 in human aortic endothelial cells.Q34299368
Periodontal diseases.Q34468885
Beyond the red complex and into more complexity: the polymicrobial synergy and dysbiosis (PSD) model of periodontal disease etiology.Q34470176
Structural Dissection and In Vivo Effectiveness of a Peptide Inhibitor of Porphyromonas gingivalis Adherence to Streptococcus gordoniiQ34484719
Microbial interactions in building of communitiesQ34518087
The subgingival microbiome in health and periodontitis and its relationship with community biomass and inflammationQ34543230
The serine phosphatase SerB of Porphyromonas gingivalis suppresses IL-8 production by dephosphorylation of NF-κB RelA/p65Q34699747
The atherogenic bacterium Porphyromonas gingivalis evades circulating phagocytes by adhering to erythrocytesQ34740007
Roles of the host oxidative immune response and bacterial antioxidant rubrerythrin during Porphyromonas gingivalis infection.Q34862986
Review of osteoimmunology and the host response in endodontic and periodontal lesionsQ34920792
A Porphyromonas gingivalis haloacid dehalogenase family phosphatase interacts with human phosphoproteins and is important for invasionQ34984268
Corruption of innate immunity by bacterial proteasesQ35003110
Origin and function of the cellular components in gingival crevice fluidQ35092082
The pathogenic persona of community-associated oral streptococciQ35640402
"Gum bug, leave my heart alone!"--epidemiologic and mechanistic evidence linking periodontal infections and atherosclerosis.Q35866675
Distinct and complex bacterial profiles in human periodontitis and health revealed by 16S pyrosequencingQ35979362
Porphyromonas gingivalis promotes Th17 inducing pathways in chronic periodontitisQ36157309
Microbial carriage state of peripheral blood dendritic cells (DCs) in chronic periodontitis influences DC differentiation, atherogenic potential.Q36284016
Local complement-targeted intervention in periodontitis: proof-of-concept using a C5a receptor (CD88) antagonistQ36417215
Role of TLR2-dependent IL-10 production in the inhibition of the initial IFN-γ T cell response to Porphyromonas gingivalis.Q36476646
The role of T cells in periodontal disease: homeostasis and autoimmunityQ36703937
Role of differential expression of streptococcal arginine deiminase in inhibition of fimA expression in Porphyromonas gingivalisQ36747267
Porphyromonas gingivalis-nucleoside-diphosphate-kinase inhibits ATP-induced reactive-oxygen-species via P2X7 receptor/NADPH-oxidase signalling and contributes to persistence.Q36763229
A novel class of lipoprotein lipase-sensitive molecules mediates Toll-like receptor 2 activation by Porphyromonas gingivalisQ36804694
Bacterial invasion of epithelial cells and spreading in periodontal tissueQ36824616
Exploring the genetic basis of chronic periodontitis: a genome-wide association studyQ36839033
Subgingival biofilm formationQ36880067
Suppression of T-cell chemokines by Porphyromonas gingivalisQ36970761
Binding of complement inhibitor C4b-binding protein contributes to serum resistance of Porphyromonas gingivalisQ37015215
Induction of bone loss by pathobiont-mediated Nod1 signaling in the oral cavityQ37040382
Importance of TLR2 in early innate immune response to acute pulmonary infection with Porphyromonas gingivalis in miceQ37059185
The human microbiome: from symbiosis to pathogenesisQ37064798
Porphyromonas gingivalis RgpA-Kgp proteinase-adhesin complexes penetrate gingival tissue and induce proinflammatory cytokines or apoptosis in a concentration-dependent mannerQ37099426
Serine lipids of Porphyromonas gingivalis are human and mouse Toll-like receptor 2 ligandsQ37123738
A new inflammatory cytokine on the block: re-thinking periodontal disease and the Th1/Th2 paradigm in the context of Th17 cells and IL-17.Q37249268
Modulation of TLR2 protein expression by miR-105 in human oral keratinocytesQ37371743
Negative correlation of distributions of Streptococcus cristatus and Porphyromonas gingivalis in subgingival plaqueQ37451753
Disulfide formation in the ER and mitochondria: two solutions to a common process.Q37508527
Neutrophil homeostasis and periodontal health in children and adultsQ37594566
Crosstalk pathways between Toll-like receptors and the complement systemQ37691806
Comparison of neutrophil functions in aggressive and chronic periodontitisQ37733777
Genetic and environmental risk factors for chronic periodontitis and aggressive periodontitisQ37733780
Periodontitis: a polymicrobial disruption of host homeostasisQ37761827
Destructive and protective roles of cytokines in periodontitis: a re-appraisal from host defense and tissue destruction viewpointsQ37782516
Targeting IL-17 and TH17 cells in chronic inflammationQ38047820
Mucosal innate immune cells regulate both gut homeostasis and intestinal inflammationQ38177725
Mechanisms of resistance of Porphyromonas gingivalis to killing by serum complementQ38481466
Distinct transcriptional profiles characterize oral epithelium-microbiota interactionsQ38520459
Microbial complexes in subgingival plaqueQ38553206
Analysis of the intracellular fate of Legionella pneumophila mutantsQ38559824
Porphyromonas gingivalis induction of microRNA-203 expression controls suppressor of cytokine signaling 3 in gingival epithelial cellsQ38686982
Local chemokine paralysis, a novel pathogenic mechanism for Porphyromonas gingivalis.Q39570767
Exit of intracellular Porphyromonas gingivalis from gingival epithelial cells is mediated by endocytic recycling pathwayQ39620387
Streptococcus cristatus ArcA interferes with Porphyromonas gingivalis pathogenicity in miceQ39745708
P433issue2
P407language of work or nameEnglishQ1860
P921main subjectPorphyromonas gingivalisQ3214147
P304page(s)328-338
P577publication date2014-02-01
P1433published inEuropean Journal of ImmunologyQ5412727
P1476titleBreaking bad: manipulation of the host response by Porphyromonas gingivalis
P478volume44

Reverse relations

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Q87452148Welcome aboard!
Q89134087[Cloning, expression, and purification of c-di-AMP metabolism-related genes from Porphyromonas gingivalis]
Q93346764[Expression of triggering receptors expressed by myeloid cells-1 in macrophages stimulated by Porphyromonas gingivalis-lipopolysaccharide]

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