| scholarly article | Q13442814 |
| review article | Q7318358 |
| P50 | author | John D. Lambris | Q6228220 |
| George Hajishengallis | Q39672238 | ||
| P2860 | cites work | HCV core protein interaction with gC1q receptor inhibits Th1 differentiation of CD4+ T cells via suppression of dendritic cell IL-12 production | Q24294460 |
| gC1q receptor ligation selectively down-regulates human IL-12 production through activation of the phosphoinositide 3-kinase pathway | Q24336138 | ||
| An anti-inflammatory function for the complement anaphylatoxin C5a-binding protein, C5L2 | Q24337675 | ||
| Microbe sensing, positive feedback loops, and the pathogenesis of inflammatory diseases | Q24647287 | ||
| Porphyromonas gingivalis-host interactions: open war or intelligent guerilla tactics? | Q24655246 | ||
| Function, structure and therapeutic potential of complement C5a receptors | Q24669712 | ||
| Porphyromonas gingivalis fimbriae proactively modulate beta2 integrin adhesive activity and promote binding to and internalization by macrophages | Q24678639 | ||
| The dark side of C5a in sepsis | Q28252425 | ||
| Direct extracellular interaction between the early secreted antigen ESAT-6 of Mycobacterium tuberculosis and TLR2 inhibits TLR signaling in macrophages | Q28301043 | ||
| C5L2, a nonsignaling C5A binding protein | Q28565469 | ||
| Phosphoinositide-mediated adaptor recruitment controls Toll-like receptor signaling | Q28593045 | ||
| Systems biology of innate immunity | Q28752485 | ||
| Recognition of microorganisms and activation of the immune response | Q29617903 | ||
| IL-17 family cytokines and the expanding diversity of effector T cell lineages | Q29619361 | ||
| Transcriptional suppression of interleukin-12 gene expression following phagocytosis of apoptotic cells | Q31813068 | ||
| C1q differentially modulates phagocytosis and cytokine responses during ingestion of apoptotic cells by human monocytes, macrophages, and dendritic cells. | Q33745559 | ||
| The C5a receptor (C5aR) C5L2 is a modulator of C5aR-mediated signal transduction. | Q33748190 | ||
| Complement activation by CpG in a human whole blood loop system: mechanisms and immunomodulatory effects | Q33801802 | ||
| Locally produced complement fragments C5a and C3a provide both costimulatory and survival signals to naive CD4+ T cells | Q34760201 | ||
| Host innate immune receptors and beyond: making sense of microbial infections | Q34785533 | ||
| The role of the anaphylatoxins in health and disease | Q34983578 | ||
| Isoforms of mammalian adenylyl cyclase: multiplicities of signaling | Q35679436 | ||
| The role of complement in the development of systemic lupus erythematosus | Q35698485 | ||
| Regulation of Toll-like receptor-mediated inflammatory response by complement in vivo | Q35850677 | ||
| CD46 in Neisseria pathogenesis | Q35879538 | ||
| The role of complement in inflammatory diseases from behind the scenes into the spotlight | Q35963146 | ||
| Toll-like receptors, endogenous ligands, and systemic autoimmune disease. | Q36079856 | ||
| The dynamics of LPS recognition: complex orchestration of multiple receptors | Q36096351 | ||
| The classical and regulatory functions of C1q in immunity and autoimmunity | Q36299455 | ||
| Membrane complement regulatory proteins | Q36336220 | ||
| The role of complement in danger sensing and transmission | Q36499763 | ||
| How microorganisms tip the balance between interleukin-12 family members | Q37033837 | ||
| Subversion of innate immunity by periodontopathic bacteria via exploitation of complement receptor-3 | Q37113561 | ||
| Induction of distinct TLR2-mediated proinflammatory and proadhesive signaling pathways in response to Porphyromonas gingivalis fimbriae | Q37200512 | ||
| When signaling pathways collide: positive and negative regulation of toll-like receptor signal transduction | Q37217884 | ||
| Increased IL-23 secretion and altered chemokine production by dendritic cells upon CD46 activation in patients with multiple sclerosis | Q37243469 | ||
| A new inflammatory cytokine on the block: re-thinking periodontal disease and the Th1/Th2 paradigm in the context of Th17 cells and IL-17. | Q37249268 | ||
| Harmful molecular mechanisms in sepsis | Q37273299 | ||
| Complement promotes the development of inflammatory T-helper 17 cells through synergistic interaction with Toll-like receptor signaling and interleukin-6 production | Q37291621 | ||
| CD14-Mac-1 interactions in Bacillus anthracis spore internalization by macrophages | Q37310685 | ||
| Human genetic deficiencies reveal the roles of complement in the inflammatory network: lessons from nature | Q37320731 | ||
| Functional roles for C5a receptors in sepsis | Q37367089 | ||
| The ins and outs of leukocyte integrin signaling | Q37419383 | ||
| The human complement fragment receptor, C5L2, is a recycling decoy receptor. | Q39902889 | ||
| Generation of inhibitory NFkappaB complexes and phosphorylated cAMP response element-binding protein correlates with the anti-inflammatory activity of complement protein C1q in human monocytes | Q40185662 | ||
| TLR2 transmodulates monocyte adhesion and transmigration via Rac1- and PI3K-mediated inside-out signaling in response to Porphyromonas gingivalis fimbriae | Q40271727 | ||
| Peptide mapping of bacterial fimbrial epitopes interacting with pattern recognition receptors | Q40380207 | ||
| Evidence for a functional role of the second C5a receptor C5L2. | Q40443506 | ||
| Cross-talk between CD14 and complement receptor 3 promotes phagocytosis of mycobacteria: regulation by phosphatidylinositol 3-kinase and cytohesin-1. | Q40445044 | ||
| Toll-like receptor 2-mediated NF-kappa B activation requires a Rac1-dependent pathway | Q40819427 | ||
| Microbial hijacking of complement-toll-like receptor crosstalk | Q42911622 | ||
| Complement receptor 3 blockade promotes IL-12-mediated clearance of Porphyromonas gingivalis and negates its virulence in vivo | Q43985683 | ||
| Chemotaxis inhibitory protein of Staphylococcus aureus binds specifically to the C5a and formylated peptide receptor | Q44903281 | ||
| C5a negatively regulates toll-like receptor 4-induced immune responses | Q44924554 | ||
| Integrin activation by bacterial fimbriae through a pathway involving CD14, Toll-like receptor 2, and phosphatidylinositol-3-kinase | Q45288377 | ||
| Mechanism of suppression of cell-mediated immunity by measles virus | Q45770172 | ||
| C1q and MBL, components of the innate immune system, influence monocyte cytokine expression. | Q45973916 | ||
| Rewiring phagocytic signal transduction. | Q45989926 | ||
| G(i)-protein-dependent inhibition of IL-12 production is mediated by activation of the phosphatidylinositol 3-kinase-protein 3 kinase B/Akt pathway and JNK. | Q46664094 | ||
| Selective suppression of IL-12 production by human herpesvirus 6. | Q47800124 | ||
| Fimbrial proteins of porphyromonas gingivalis mediate in vivo virulence and exploit TLR2 and complement receptor 3 to persist in macrophages. | Q54476982 | ||
| Dendritic cell function in allostimulation is modulated by C5aR signaling. | Q54712683 | ||
| C1q enhances IFN-gamma production by antigen-specific T cells via the CD40 costimulatory pathway on dendritic cells. | Q54770577 | ||
| Active MAC-1 (CD11b/CD18) on DCs inhibits full T-cell activation | Q58807981 | ||
| C5L2 is critical for the biological activities of the anaphylatoxins C5a and C3a | Q59097002 | ||
| Complement protein C1q induces maturation of human dendritic cells | Q60861601 | ||
| A global analysis of cross-talk in a mammalian cellular signalling network | Q83339233 | ||
| P433 | issue | 4 | |
| P921 | main subject | toll-like receptor | Q408004 |
| P304 | page(s) | 154-163 | |
| P577 | publication date | 2010-02-10 | |
| P1433 | published in | Trends in Immunology | Q15265730 |
| P1476 | title | Crosstalk pathways between Toll-like receptors and the complement system | |
| P478 | volume | 31 |
| Q34468902 | A mathematical model of CR3/TLR2 crosstalk in the context of Francisella tularensis infection |
| Q35108521 | A systems biological approach reveals multiple crosstalk mechanism between gram-positive and negative bacterial infections: an insight into core mechanism and unique molecular signatures |
| Q34086998 | Absence of signaling into CD4⁺ cells via C3aR and C5aR enables autoinductive TGF-β1 signaling and induction of Foxp3⁺ regulatory T cells. |
| Q35103285 | Activated microglia proliferate at neurites of mutant huntingtin-expressing neurons |
| Q34412613 | Albumin-based Microbubbles Bind Up-regulated Scavenger Receptors following Vascular Injury |
| Q35922386 | Alternative Pathway Inhibition by Exogenous Factor H Fails to Attenuate Inflammation and Vascular Leakage in Experimental Pneumococcal Sepsis in Mice |
| Q57191731 | Anaphylatoxin Receptors C3aR and C5aR1 Are Important Factors That Influence the Impact of Ethanol on the Adipose Secretome |
| Q33418637 | Antisense oligonucleotide therapies: the promise and the challenges from a toxicologic pathologist's perspective |
| Q37983788 | Astrocyte immune responses in epilepsy |
| Q37586359 | Breaking bad: manipulation of the host response by Porphyromonas gingivalis. |
| Q36107219 | C5a and toll-like receptor 4 crosstalk in retinal pigment epithelial cells |
| Q60628150 | C5aR1 interacts with TLR2 in osteoblasts and stimulates the osteoclast-inducing chemokine CXCL10 |
| Q35565857 | CD14 and complement crosstalk and largely mediate the transcriptional response to Escherichia coli in human whole blood as revealed by DNA microarray |
| Q91959121 | Ca2+/Calmodulin-dependent kinase II delta B is essential for cardiomyocyte hypertrophy and complement gene expression after LPS and HSP60 stimulation in vitro |
| Q40306336 | Cell-specific deletion of C1qa identifies microglia as the dominant source of C1q in mouse brain |
| Q39092541 | Chimeric anti-CD14 IGG2/4 Hybrid antibodies for therapeutic intervention in pig and human models of inflammation |
| Q92035579 | Clinical promise of next-generation complement therapeutics |
| Q47883886 | Combination Therapy with Low-Dose IVIG and a C1-esterase Inhibitor Ameliorates Brain Damage and Functional Deficits in Experimental Ischemic Stroke |
| Q45877606 | Combination of a TLR4 ligand and anaphylatoxin C5a for the induction of antigen-specific cytotoxic T cell responses |
| Q61449507 | Complement Activation as a Helping Hand for Inflammophilic Pathogens and Cancer |
| Q55354503 | Complement Activation in Inflammatory Skin Diseases. |
| Q40444704 | Complement Component 3 Regulates IFN-α Production by Plasmacytoid Dendritic Cells following TLR7 Activation by a Plant Virus-like Nanoparticle. |
| Q26797414 | Complement Involvement in Periodontitis: Molecular Mechanisms and Rational Therapeutic Approaches |
| Q52597637 | Complement Receptor 3-Mediated Inhibition of Inflammasome Priming by Ras GTPase-Activating Protein During Francisella tularensis Phagocytosis by Human Mononuclear Phagocytes. |
| Q61800178 | Complement Receptor C5aR1 Inhibition Reduces Pyroptosis in hDPP4-Transgenic Mice Infected with MERS-CoV |
| Q92646754 | Complement activation in obesity, insulin resistance, and type 2 diabetes mellitus |
| Q26862615 | Complement and dysbiosis in periodontal disease |
| Q37769810 | Complement and periodontitis. |
| Q34162421 | Complement and viral pathogenesis |
| Q38558926 | Complement component C3 - The "Swiss Army Knife" of innate immunity and host defense |
| Q37531649 | Complement factor B is the downstream effector of TLRs and plays an important role in a mouse model of severe sepsis. |
| Q33432423 | Complement in disease: a defence system turning offensive |
| Q36756850 | Complement in immune and inflammatory disorders: pathophysiological mechanisms |
| Q41497854 | Complement inhibition attenuates acute kidney injury after ischemia-reperfusion and limits progression to renal fibrosis in mice. |
| Q37180462 | Complement inhibition in pre-clinical models of periodontitis and prospects for clinical application |
| Q40506861 | Complement mediates a primed inflammatory response after traumatic lung injury |
| Q34366931 | Complement modulates the cutaneous microbiome and inflammatory milieu |
| Q34364911 | Complement opsonization of HIV-1 results in decreased antiviral and inflammatory responses in immature dendritic cells via CR3 |
| Q61441031 | Complement plays a central role in Candida albicans-induced cytokine production by human PBMCs |
| Q36460034 | Complement therapeutics in inflammatory diseases: promising drug candidates for C3-targeted intervention |
| Q64102307 | Complement-Dependent Mechanisms and Interventions in Periodontal Disease |
| Q36302901 | Complement-targeted therapeutics in periodontitis |
| Q29615484 | Complement: a key system for immune surveillance and homeostasis |
| Q34501875 | Complementing the inflammasome. |
| Q54216769 | Dengue virus induces increased activity of the complement alternative pathway in infected cells. |
| Q38897358 | Development of mucosal immunity in children: a rationale for sublingual immunotherapy? |
| Q40110537 | Distinct herpesvirus resistances and immune responses of three gynogenetic clones of gibel carp revealed by comprehensive transcriptomes. |
| Q39729995 | Double blockade of CD14 and complement C5 abolishes the cytokine storm and improves morbidity and survival in polymicrobial sepsis in mice |
| Q28077955 | Dual inhibition of complement and Toll-like receptors as a novel approach to treat inflammatory diseases-C3 or C5 emerge together with CD14 as promising targets |
| Q47952463 | Errant gardeners: glial-cell-dependent synaptic pruning and neurodevelopmental disorders |
| Q28485277 | Fine tuning inflammation at the front door: macrophage complement receptor 3-mediates phagocytosis and immune suppression for Francisella tularensis |
| Q30582298 | Genetic and intervention studies implicating complement C3 as a major target for the treatment of periodontitis |
| Q38716217 | Gingipain of Porphyromonas gingivalis manipulates M1 macrophage polarization through C5a pathway |
| Q40513220 | HIV-1-derived single-stranded RNA acts as activator of human neutrophils |
| Q40561877 | HIV-1-neutrophil interactions trigger neutrophil activation and Toll-like receptor expression |
| Q47589005 | HMGB1-induced angiogenesis in perforated disc cells of human temporomandibular joint. |
| Q58603861 | Harmful Roles of TLR3 and TLR9 in Cardiac Dysfunction Developing during Polymicrobial Sepsis |
| Q35866976 | Higher Throughput Quantification of Neutralizing Antibody to Herpes Simplex Viruses |
| Q34018825 | Human pentraxin 3 binds to the complement regulator c4b-binding protein. |
| Q90068078 | Identification of an Increased Alveolar Macrophage Subpopulation in Old Mice That Displays Unique Inflammatory Characteristics and Is Permissive to Mycobacterium tuberculosis Infection |
| Q38229557 | IgG4-related disease and its pathogenesis-cross-talk between innate and acquired immunity |
| Q39424405 | Increased nucleic Acid receptor expression in chronic periodontitis |
| Q44758803 | Induction of Antiviral Immune Response through Recognition of the Repeating Subunit Pattern of Viral Capsids Is Toll-Like Receptor 2 Dependent. |
| Q30660501 | Infection-induced NETosis is a dynamic process involving neutrophil multitasking in vivo. |
| Q36717275 | Inhibition of pre-existing natural periodontitis in non-human primates by a locally administered peptide inhibitor of complement C3 |
| Q38803235 | Injection site reactions after subcutaneous oligonucleotide therapy |
| Q38991032 | Injury site-specific targeting of complement inhibitors for treating stroke |
| Q92110459 | Innate Immune Recognition: An Issue More Complex Than Expected |
| Q38120744 | Innate immunity and neuroinflammation |
| Q37528466 | Integrin CD11b positively regulates TLR4-induced signalling pathways in dendritic cells but not in macrophages |
| Q36022738 | Interactions between coagulation and complement--their role in inflammation |
| Q49551272 | Leishmania donovani Inhibitor of Serine Peptidases 2 Mediated Inhibition of Lectin Pathway and Upregulation of C5aR Signaling Promote Parasite Survival inside Host |
| Q38757564 | Let's Tie the Knot: Marriage of Complement and Adaptive Immunity in Pathogen Evasion, for Better or Worse |
| Q53698113 | Linkage of Infection to Adverse Systemic Complications: Periodontal Disease, Toll-Like Receptors, and Other Pattern Recognition Systems. |
| Q36417215 | Local complement-targeted intervention in periodontitis: proof-of-concept using a C5a receptor (CD88) antagonist |
| Q24594632 | Low-abundance biofilm species orchestrates inflammatory periodontal disease through the commensal microbiota and complement |
| Q41426465 | M cells expressing the complement C5a receptor are efficient targets for mucosal vaccine delivery. |
| Q34008200 | Mechanism and implications of CXCR4-mediated integrin activation by Porphyromonas gingivalis |
| Q38672397 | Meconium-induced inflammation and surfactant inactivation: specifics of molecular mechanisms |
| Q30499616 | Microbial manipulation of receptor crosstalk in innate immunity |
| Q64103359 | Modulation of Iberian Ribbed Newt Complement Component C3 by Stressors Similar to those Encountered during a Stay Onboard the International Space Station |
| Q50193589 | Molecular basis for immunohistochemical and inflammatory changes during progression of gingivitis to periodontitis |
| Q38991040 | More than complementing Tolls: complement-Toll-like receptor synergy and crosstalk in innate immunity and inflammation |
| Q35609638 | MyD88-dependent production of IL-17F is modulated by the anaphylatoxin C5a via the Akt signaling pathway |
| Q50132332 | Mycobacterial Phenolic Glycolipids Selectively Disable TRIF-Dependent TLR4 Signaling in Macrophages |
| Q28082379 | On the Functional Overlap between Complement and Anti-Microbial Peptides |
| Q36750759 | Organ-specific features of natural killer cells |
| Q35767677 | Pathogenesis of aortic dilatation in mucopolysaccharidosis VII mice may involve complement activation |
| Q35544574 | Pathogenic microbes and community service through manipulation of innate immunity |
| Q84301195 | Poly(methyl vinyl ether-co-maleic anhydride) nanoparticles as innate immune system activators |
| Q35247803 | Post challenge inhibition of C3 and CD14 attenuates Escherichia coli-induced inflammation in human whole blood |
| Q38799808 | Proteomic profiling of dextran sulfate sodium induced acute ulcerative colitis mice serum exosomes and their immunomodulatory impact on macrophages |
| Q30430960 | Regulation of NK cell repertoire and function in the liver |
| Q38044665 | Restraint of inflammatory signaling by interdependent strata of negative regulatory pathways |
| Q50516275 | Revisiting the Page & Schroeder model: the good, the bad and the unknowns in the periodontal host response 40 years later. |
| Q34727808 | Role of complement in host-microbe homeostasis of the periodontium |
| Q38365365 | Scientific and Regulatory Policy Committee Points-to-consider Paper*: Drug-induced Vascular Injury Associated with Nonsmall Molecule Therapeutics in Preclinical Development: Part 2. Antisense Oligonucleotides |
| Q64087538 | Significance of Complement System in Ischemic Stroke: A Comprehensive Review |
| Q44961349 | Single nucleotide polymorphisms of pattern recognition receptors and chronic periodontitis |
| Q37634416 | Synergistic interaction between C5a and NOD2 signaling in the regulation of chemokine expression in RAW 264.7 macrophages |
| Q36813665 | Synovium and the innate inflammatory network in osteoarthritis progression |
| Q90305577 | Systems analysis-based assessment of post-treatment adverse events in lymphatic filariasis |
| Q24630948 | TLR activation enhances C5a-induced pro-inflammatory responses by negatively modulating the second C5a receptor, C5L2 |
| Q34786821 | TLR-signaling networks: an integration of adaptor molecules, kinases, and cross-talk. |
| Q24618908 | The C5a receptor impairs IL-12-dependent clearance of Porphyromonas gingivalis and is required for induction of periodontal bone loss |
| Q33863754 | The Controversial C5a Receptor C5aR2: Its Role in Health and Disease |
| Q35846150 | The amphioxus genome provides unique insight into the evolution of immunity |
| Q39014623 | The anti-inflammatory effect of combined complement and CD14 inhibition is preserved during escalating bacterial load |
| Q38211992 | The complement system in inflammatory bowel disease |
| Q35237967 | The effect of Tlr4 and/or C3 deficiency and of neonatal gene therapy on skeletal disease in mucopolysaccharidosis VII mice |
| Q28086874 | The ischemic environment drives microglia and macrophage function |
| Q35897744 | Toll-Like Receptors Promote Mitochondrial Translocation of Nuclear Transcription Factor Nuclear Factor of Activated T-Cells in Prolonged Microglial Activation. |
| Q60925110 | Toll-like receptor 2 confers partial neuroprotection during prion disease |
| Q27692121 | Toll-like receptors (TLRs) and mannan-binding lectin (MBL): on constant alert in a hostile environment |
| Q27010697 | Toll-like receptors in the host defense against Pseudomonas aeruginosa respiratory infection and cystic fibrosis |
| Q43044462 | Toward Personalized Network Biomarkers in Alzheimer's Disease: Computing Individualized Genomic and Protein Crosstalk Maps |
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