| scholarly article | Q13442814 |
| review article | Q7318358 |
| P50 | author | George Hajishengallis | Q39672238 |
| P2093 | author name string | George Hajishengallis | |
| P2860 | cites work | Complement: coming full circle. | Q37623518 |
| Therapeutic potential of complement modulation | Q37644190 | ||
| The role of the neutrophil in rheumatoid arthritis | Q37680243 | ||
| Crosstalk pathways between Toll-like receptors and the complement system | Q37691806 | ||
| Too old to fight? Aging and its toll on innate immunity | Q37715721 | ||
| Periodontitis: a polymicrobial disruption of host homeostasis | Q37761827 | ||
| Mechanisms of resistance of Porphyromonas gingivalis to killing by serum complement | Q38481466 | ||
| Microbial complexes in subgingival plaque | Q38553206 | ||
| Gingival fluid and serum in periodontal diseases. I. Quantitative study of immunoglobulins, complement components, and other plasma proteins | Q39466529 | ||
| Complement factors in gingival crevice material from healthy and inflamed gingiva in humans | Q39734410 | ||
| Porphyromonas gingivalis mediates the shedding and proteolysis of complement regulatory protein CD46 expressed by oral epithelial cells | Q39809096 | ||
| The human complement fragment receptor, C5L2, is a recycling decoy receptor. | Q39902889 | ||
| Differential interactions of fimbriae and lipopolysaccharide from Porphyromonas gingivalis with the Toll-like receptor 2-centred pattern recognition apparatus | Q40230062 | ||
| TLR2 transmodulates monocyte adhesion and transmigration via Rac1- and PI3K-mediated inside-out signaling in response to Porphyromonas gingivalis fimbriae | Q40271727 | ||
| Peptide mapping of bacterial fimbrial epitopes interacting with pattern recognition receptors | Q40380207 | ||
| Intracellular signaling and cytokine induction upon interactions of Porphyromonas gingivalis fimbriae with pattern-recognition receptors | Q40545709 | ||
| Identification of C 3a, IgG, IgM in Inflamed Human Gingiva | Q40557064 | ||
| Combinational clustering of receptors following stimulation by bacterial products determines lipopolysaccharide responses | Q40574382 | ||
| Detection of Functional Complement Components in Gingival Crevicular Fluid from Humans with Periodontal Disease | Q40765711 | ||
| Gingival Fluid and Serum in Periodontal Diseases: II. Evidence for Cleavage of Complement Components C3, C3 Proactivator (Factor B) and C4 in Gingival Fluid | Q40839980 | ||
| Direct anti-inflammatory effect of a bacterial virulence factor: IL-10-dependent suppression of IL-12 production by filamentous hemagglutinin from Bordetella pertussis | Q40900630 | ||
| Fifth complement cascade protein (C5) cleavage fragments disrupt the SDF-1/CXCR4 axis: further evidence that innate immunity orchestrates the mobilization of hematopoietic stem/progenitor cells | Q41004835 | ||
| Outside-in signaling by lipopolysaccharide through a tailless integrin | Q41103047 | ||
| Deposits of immunoglobulins, complement, and immune complexes in inflamed human gingiva | Q41448063 | ||
| The gingival tissues: the architecture of periodontal protection | Q41754677 | ||
| Stimulation of human rheumatoid synovial cells by non-lethal complement membrane attack | Q42479395 | ||
| Complement-induced phospholipase A2 activation in experimental membranous nephropathy | Q42485155 | ||
| Microbial hijacking of complement-toll-like receptor crosstalk | Q42911622 | ||
| Single nucleotide polymorphisms of complement component 5 and periodontitis | Q43243486 | ||
| Complement receptor 3 blockade promotes IL-12-mediated clearance of Porphyromonas gingivalis and negates its virulence in vivo | Q43985683 | ||
| Complement factor 5 is a quantitative trait gene that modifies liver fibrogenesis in mice and humans | Q44042948 | ||
| Adhesins encoded by the gingipain genes of Porphyromonas gingivalis are responsible for co-aggregation with Prevotella intermedia | Q44425221 | ||
| Properdin can initiate complement activation by binding specific target surfaces and providing a platform for de novo convertase assembly | Q44441855 | ||
| Oral health and mortality risk from pneumonia in the elderly | Q44468713 | ||
| C5a negatively regulates toll-like receptor 4-induced immune responses | Q44924554 | ||
| Integrin activation by bacterial fimbriae through a pathway involving CD14, Toll-like receptor 2, and phosphatidylinositol-3-kinase | Q45288377 | ||
| Rewiring phagocytic signal transduction. | Q45989926 | ||
| Over-expression of forkhead box P3 and its association with receptor activator of nuclear factor-kappa B ligand, interleukin (IL) -17, IL-10 and transforming growth factor-beta during the progression of chronic periodontitis. | Q46023685 | ||
| Activation of complement components C3 and C5 by a cysteine proteinase (gingipain-1) from Porphyromonas (Bacteroides) gingivalis. | Q46312320 | ||
| Evidence of the presence of T helper type 17 cells in chronic lesions of human periodontal disease | Q46484299 | ||
| Involvement of periodontopathic anaerobes in aspiration pneumonia | Q46796488 | ||
| Innate immune recognition of invasive bacteria accelerates atherosclerosis in apolipoprotein E-deficient mice | Q47658739 | ||
| Regulation by C5a of neutrophil activation during sepsis | Q47672797 | ||
| Complement-dependent stimulation of prostaglandin synthesis and bone resorption | Q47851391 | ||
| The complement receptor 1, CR1 (CD35), mediates inhibitory signals in human T-lymphocytes. | Q53643906 | ||
| Role for endotoxin and complement in periodontal tissue destruction. | Q53772162 | ||
| The involvement of IL-23 and the Th17 pathway in periodontitis. | Q54473229 | ||
| Fimbrial proteins of porphyromonas gingivalis mediate in vivo virulence and exploit TLR2 and complement receptor 3 to persist in macrophages. | Q54476982 | ||
| Surface protease of Treponema denticola hydrolyzes C3 and influences function of polymorphonuclear leukocytes | Q57920105 | ||
| C5L2 is critical for the biological activities of the anaphylatoxins C5a and C3a | Q59097002 | ||
| Complement and C4 Null Alleles in Severe Chronic Adult Periodontitis | Q59244326 | ||
| Roles of the Alternative Complement Pathway and C1q during Innate Immunity to Streptococcus pyogenes | Q63257860 | ||
| Protection of Gingival Epithelium against Complement-mediated Damage by Strong Expression of the Membrane Attack Complex Inhibitor Protectin (CD59) | Q63305217 | ||
| Simultaneous assessment of complement components C3, C4, and B and their cleavage products in human gingival fluid. II. Longitudinal changes during periodontal therapy | Q67299794 | ||
| Assessment of complement cleavage in gingival fluid during experimental gingivitis in man | Q69484403 | ||
| Transmigration and infiltration of leucocytes in human junctional epithelium | Q69505575 | ||
| Assessment of complement cleavage in gingival fluid in humans with and without periodontal disease | Q69996935 | ||
| Neutrophils and IgG at the host-plaque interface on children's teeth | Q71996838 | ||
| Biosynthesis of complement components in chronically inflamed gingiva | Q72763051 | ||
| C-1 esterase inhibitor dysfunction localised to the periodontal tissues: clues to the role of stress in the pathogenesis of chronic periodontitis? | Q73111757 | ||
| IL-1 and TNF antagonists inhibit the inflammatory response and bone loss in experimental periodontitis | Q74463699 | ||
| Senescence in innate immune responses: reduced neutrophil phagocytic capacity and CD16 expression in elderly humans | Q77337997 | ||
| Role of ICAM-1 and ICAM-2 and alternate CD11/CD18 ligands in neutrophil transendothelial migration | Q77787136 | ||
| Role of complement component C1q in the IgG-independent opsonophagocytosis of group B streptococcus | Q78145251 | ||
| Treatment of periodontitis and endothelial function | Q79848712 | ||
| Biphasic effect of gingipains from Porphyromonas gingivalis on the human complement system | Q80358557 | ||
| Low mannose-binding lectin (MBL) levels in neonates with pneumonia and sepsis | Q80824122 | ||
| Mannose-binding lectin and mannose-binding lectin-associated serine protease 2 in susceptibility, severity, and outcome of pneumonia in adults | Q81532915 | ||
| Levels of interleukin-17 in gingival crevicular fluid and in supernatants of cellular cultures of gingival tissue from patients with chronic periodontitis | Q81614908 | ||
| Factor H-related protein 1 (CFHR-1) inhibits complement C5 convertase activity and terminal complex formation | Q84071466 | ||
| Cytochemistry and ultrastructure of gingival sulcus cells | Q93839036 | ||
| The C5a chemoattractant receptor mediates mucosal defence to infection | Q24318486 | ||
| Porphyromonas gingivalis-host interactions: open war or intelligent guerilla tactics? | Q24655246 | ||
| Function, structure and therapeutic potential of complement C5a receptors | Q24669712 | ||
| Porphyromonas gingivalis fimbriae proactively modulate beta2 integrin adhesive activity and promote binding to and internalization by macrophages | Q24678639 | ||
| Resolution of inflammation: a new paradigm for the pathogenesis of periodontal diseases | Q28206660 | ||
| Complement-induced impairment of innate immunity during sepsis | Q28221448 | ||
| The dark side of C5a in sepsis | Q28252425 | ||
| The classical complement cascade mediates CNS synapse elimination | Q28261273 | ||
| Cell signals transduced by complement | Q28268676 | ||
| Targeting to Fcgamma receptors, but not CR3 (CD11b/CD18), increases clearance of Bordetella pertussis | Q28511441 | ||
| Identification of two distinct mechanisms of phagocytosis controlled by different Rho GTPases | Q29614245 | ||
| Complement: a key system for immune surveillance and homeostasis | Q29615484 | ||
| Points of control in inflammation | Q29620319 | ||
| Complement-dependent clearance of apoptotic cells by human macrophages | Q30442812 | ||
| Specific inhibition of the classical complement pathway by C1q-binding peptides. | Q30776720 | ||
| Transcriptional suppression of interleukin-12 gene expression following phagocytosis of apoptotic cells | Q31813068 | ||
| Animal models for Porphyromonas gingivalis-mediated periodontal disease. | Q31958913 | ||
| Gene expression in periodontal tissues following treatment | Q33349622 | ||
| The spectrum of complement alternative pathway-mediated diseases | Q33380274 | ||
| Complement regulators and inhibitory proteins | Q33386110 | ||
| Neutrophil fate in gingival crevicular fluid | Q33523593 | ||
| Periodontal microbiota and carotid intima-media thickness: the Oral Infections and Vascular Disease Epidemiology Study (INVEST) | Q33616752 | ||
| Complement evasion by human pathogens | Q33623972 | ||
| Mobilization studies in complement-deficient mice reveal that optimal AMD3100 mobilization of hematopoietic stem cells depends on complement cascade activation by AMD3100-stimulated granulocytes | Q33726179 | ||
| The C5a receptor (C5aR) C5L2 is a modulator of C5aR-mediated signal transduction. | Q33748190 | ||
| C-reactive protein and complement are important mediators of tissue damage in acute myocardial infarction | Q33883883 | ||
| CR3: a general purpose adhesion-recognition receptor essential for innate immunity | Q33887451 | ||
| Regulation of B lymphocyte responses to foreign and self-antigens by the CD19/CD21 complex | Q33932719 | ||
| Periodontal inflammation and bone loss in aged mice. | Q33949702 | ||
| Review article: ageing and the neutrophil: no appetite for killing? | Q33992839 | ||
| Adhesion molecule deficiencies increase Porphyromonas gingivalis-induced alveolar bone loss in mice | Q34004532 | ||
| Complement and its role in innate and adaptive immune responses | Q34088142 | ||
| Complement-targeted therapeutics | Q34255011 | ||
| Mechanisms of signal transduction activated by sublytic assembly of terminal complement complexes on nucleated cells | Q34397088 | ||
| Periodontal diseases. | Q34468885 | ||
| C5a receptor-deficient dendritic cells promote induction of Treg and Th17 cells | Q34579613 | ||
| Phagosome maturation: aging gracefully | Q34682299 | ||
| The economics of periodontal diseases | Q34725935 | ||
| Locally produced complement fragments C5a and C3a provide both costimulatory and survival signals to naive CD4+ T cells | Q34760201 | ||
| Modulation of the antitumor immune response by complement | Q34838919 | ||
| Rapid leukocyte integrin activation by chemokines | Q34862111 | ||
| Roles of the host oxidative immune response and bacterial antioxidant rubrerythrin during Porphyromonas gingivalis infection. | Q34862986 | ||
| Classifying periodontal diseases--a long-standing dilemma | Q34866426 | ||
| Therapeutic inhibition of the early phase of complement activation | Q34978616 | ||
| The role of the anaphylatoxins in health and disease | Q34983578 | ||
| Corruption of innate immunity by bacterial proteases | Q35003110 | ||
| Origin and function of the cellular components in gingival crevice fluid | Q35092082 | ||
| Humoral immune responses in gingival crevice fluid: local and systemic implications | Q35092097 | ||
| Phagocyte sabotage: disruption of macrophage signalling by bacterial pathogens | Q35120164 | ||
| Role of C5a-C5aR interaction in sepsis | Q35608139 | ||
| Regulation of Toll-like receptor-mediated inflammatory response by complement in vivo | Q35850677 | ||
| The role of complement in inflammatory diseases from behind the scenes into the spotlight | Q35963146 | ||
| Role of C5a in inflammatory responses | Q36072464 | ||
| Porphyromonas gingivalis, Treponema denticola, and Tannerella forsythia: the "red complex", a prototype polybacterial pathogenic consortium in periodontitis | Q36107786 | ||
| Neutrophil-derived cytokines: potential therapeutic targets in inflammation. | Q36230445 | ||
| MacrophAging: a cellular and molecular review. | Q36257851 | ||
| Membrane complement regulatory proteins | Q36336220 | ||
| Receptors for C3b and C3bi promote phagocytosis but not the release of toxic oxygen from human phagocytes | Q36348349 | ||
| Immune cell migration in inflammation: present and future therapeutic targets | Q36348737 | ||
| Complement receptor type 3 (CR3) binds to an Arg-Gly-Asp-containing region of the major surface glycoprotein, gp63, of Leishmania promastigotes | Q36355119 | ||
| Holding T cells in check--a new role for complement regulators? | Q36365888 | ||
| Periodontal disease and adverse pregnancy outcomes: a systematic review | Q36367800 | ||
| Essential role for the C5a receptor in regulating the effector phase of synovial infiltration and joint destruction in experimental arthritis | Q36371879 | ||
| Innate immune signaling and Porphyromonas gingivalis-accelerated atherosclerosis. | Q36376749 | ||
| Regulation of interleukin-12 by complement receptor 3 signaling | Q36377284 | ||
| The I domain is a major recognition site on the leukocyte integrin Mac-1 (CD11b/CD18) for four distinct adhesion ligands. | Q36383058 | ||
| Activator-specific requirement of properdin in the initiation and amplification of the alternative pathway complement | Q36384714 | ||
| Chemotaxis inhibitory protein of Staphylococcus aureus, a bacterial antiinflammatory agent. | Q36403878 | ||
| Oral biofilms, periodontitis, and pulmonary infections | Q36481768 | ||
| The role of reactive oxygen and antioxidant species in periodontal tissue destruction | Q36703964 | ||
| Complement and coagulation: strangers or partners in crime? | Q36750470 | ||
| Analysis of gingival crevicular fluid as applied to the diagnosis of oral and systemic diseases | Q36792241 | ||
| Porphyromonas gingivalis interactions with complement receptor 3 (CR3): innate immunity or immune evasion? | Q36814065 | ||
| Autoinflammatory syndromes with a dermatological perspective | Q36922302 | ||
| Rheumatoid arthritis and the complement system. | Q36939396 | ||
| Mechanisms of evasion of complement by Porphyromonas gingivalis. | Q36991739 | ||
| Binding of complement inhibitor C4b-binding protein contributes to serum resistance of Porphyromonas gingivalis | Q37015215 | ||
| The use of rodent models to investigate host-bacteria interactions related to periodontal diseases | Q37058550 | ||
| Importance of TLR2 in early innate immune response to acute pulmonary infection with Porphyromonas gingivalis in mice | Q37059185 | ||
| Interpain A, a cysteine proteinase from Prevotella intermedia, inhibits complement by degrading complement factor C3. | Q37097298 | ||
| Subversion of innate immunity by periodontopathic bacteria via exploitation of complement receptor-3 | Q37113561 | ||
| The alternative complement pathway revisited | Q37141297 | ||
| A protective role for the fifth complement component (c5) in allergic airway disease | Q37144283 | ||
| Analysis of a unique interaction between the complement regulatory protein factor H and the periodontal pathogen Treponema denticola. | Q37144937 | ||
| Cytokines that promote periodontal tissue destruction | Q37232626 | ||
| The management of inflammation in periodontal disease | Q37232631 | ||
| A new inflammatory cytokine on the block: re-thinking periodontal disease and the Th1/Th2 paradigm in the context of Th17 cells and IL-17. | Q37249268 | ||
| Age-related alterations in innate immune receptor expression and ability of macrophages to respond to pathogen challenge in vitro. | Q37280387 | ||
| The interaction of salivary secretions with the human complement system--a model for the study of host defense systems on inflamed mucosal surfaces | Q37302105 | ||
| Functional roles for C5a receptors in sepsis | Q37367089 | ||
| Toll gates to periodontal host modulation and vaccine therapy | Q37416211 | ||
| Periodontitis in systemic rheumatic diseases | Q37428747 | ||
| The oral microbial consortium's interaction with the periodontal innate defense system | Q37478630 | ||
| Complementary Tolls in the periodontium: how periodontal bacteria modify complement and Toll-like receptor responses to prevail in the host | Q37486358 | ||
| Inflammatory mechanisms and treatment of obstructive airway diseases with neutrophilic bronchitis. | Q37531132 | ||
| Clinical significance of complement deficiencies | Q37598280 | ||
| P433 | issue | 12 | |
| P407 | language of work or name | English | Q1860 |
| P921 | main subject | periodontitis | Q520127 |
| P304 | page(s) | 1992-2001 | |
| P577 | publication date | 2010-06-23 | |
| P1433 | published in | Biochemical Pharmacology | Q864229 |
| P1476 | title | Complement and periodontitis | |
| P478 | volume | 80 |
| Q35988440 | A Metalloproteinase Mirolysin of Tannerella forsythia Inhibits All Pathways of the Complement System |
| Q37283979 | A surface-exposed neuraminidase affects complement resistance and virulence of the oral spirochaete Treponema denticola |
| Q38753408 | Apolipoprotein E Related Co-Morbidities and Alzheimer's Disease |
| Q35932948 | Basic biology and role of interleukin-17 in immunity and inflammation |
| Q37978720 | Complement C5a: impact on the field of veterinary medicine |
| Q36803645 | Complement Factor B Production in Renal Tubular Cells and Its Role in Sodium Transporter Expression During Polymicrobial Sepsis |
| Q53385070 | Complement activation product C4d in oral and oropharyngeal squamous cell carcinoma. |
| Q26862615 | Complement and dysbiosis in periodontal disease |
| Q36302901 | Complement-targeted therapeutics in periodontitis |
| Q39848642 | Differential capacity for complement receptor-mediated immune evasion by Porphyromonas gingivalis depending on the type of innate leukocyte |
| Q28385075 | Dysbiosis and alterations in predicted functions of the subgingival microbiome in chronic periodontitis |
| Q35213862 | Elevated serum levels of mannose-binding lectin and diabetic nephropathy in type 2 diabetes |
| Q36356010 | Energy dispersive spectroscopy-scanning transmission electron microscope observations of free radical production in human polymorphonuclear leukocytes phagocytosing non-opsonized Tannerella forsythia |
| Q37632801 | Epigenetic Modulation in Periodontitis: Interaction of Adiponectin and JMJD3-IRF4 Axis in Macrophages |
| Q35229098 | Finding off-targets, biological pathways, and target diseases for chymase inhibitors via structure-based systems biology approach. |
| Q27324002 | From Mouth to Model: Combining in vivo and in vitro Oral Biofilm Growth. |
| Q30582298 | Genetic and intervention studies implicating complement C3 as a major target for the treatment of periodontitis |
| Q33594425 | Importance of Diversity in the Oral Microbiota including Candida Species Revealed by High-Throughput Technologies |
| Q36717275 | Inhibition of pre-existing natural periodontitis in non-human primates by a locally administered peptide inhibitor of complement C3 |
| Q35071902 | Inhibitory effects of areca nut extract on expression of complement receptors and fc receptors in human neutrophils |
| Q36417215 | Local complement-targeted intervention in periodontitis: proof-of-concept using a C5a receptor (CD88) antagonist |
| Q24594632 | Low-abundance biofilm species orchestrates inflammatory periodontal disease through the commensal microbiota and complement |
| Q51248294 | Mirolysin, a LysargiNase from Tannerella forsythia, proteolytically inactivates the human cathelicidin, LL-37. |
| Q41064612 | Molecular aspects of the pathogenesis of periodontitis. |
| Q50193589 | Molecular basis for immunohistochemical and inflammatory changes during progression of gingivitis to periodontitis |
| Q38991040 | More than complementing Tolls: complement-Toll-like receptor synergy and crosstalk in innate immunity and inflammation |
| Q35963446 | Oral inflammatory diseases and systemic inflammation: role of the macrophage. |
| Q92405052 | Osteoimmunology of Oral and Maxillofacial Diseases: Translational Applications Based on Biological Mechanisms |
| Q35544574 | Pathogenic microbes and community service through manipulation of innate immunity |
| Q38954801 | Periodontal and other oral manifestations of immunodeficiency diseases |
| Q35155822 | Polymicrobial synergy and dysbiosis in inflammatory disease |
| Q28083786 | Porphyromonas gingivalis Periodontal Infection and Its Putative Links with Alzheimer's Disease |
| Q34727808 | Role of complement in host-microbe homeostasis of the periodontium |
| Q41983427 | Severe periodontal disease associated with long-term treatment with intravenous immunoglobulin. |
| Q92827850 | Systemic Antibiotic Therapy Reduces Circulating Inflammatory Dendritic Cells and Treg-Th17 Plasticity in Periodontitis |
| Q24618908 | The C5a receptor impairs IL-12-dependent clearance of Porphyromonas gingivalis and is required for induction of periodontal bone loss |
| Q30486707 | The Concise Guide to PHARMACOLOGY 2013/14: G protein-coupled receptors |
| Q37074007 | The Treponema denticola FhbB Protein Is a Dominant Early Antigen That Elicits FhbB Variant-Specific Antibodies That Block Factor H Binding and Cleavage by Dentilisin |
| Q38231443 | The complement system and its role in the pathogenesis of periodontitis: current concepts. |
| Q46328514 | The periodontal war: microbes and immunity. |
| Q36804650 | The surface layer of Tannerella forsythia contributes to serum resistance and oral bacterial coaggregation |
| Q38733696 | Variants of Porphyromonas gingivalis lipopolysaccharide alter lipidation of autophagic protein, microtubule-associated protein 1 light chain 3, LC3. |
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