A Porphyromonas gingivalis Periplasmic Novel Exopeptidase, Acylpeptidyl Oligopeptidase, Releases N-Acylated Di- and Tripeptides from Oligopeptides

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A Porphyromonas gingivalis Periplasmic Novel Exopeptidase, Acylpeptidyl Oligopeptidase, Releases N-Acylated Di- and Tripeptides from Oligopeptides is …
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scholarly articleQ13442814

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P356DOI10.1074/JBC.M115.687566
P932PMC publication ID4786725
P698PubMed publication ID26733202

P2093author name stringShigenobu Kimura
Yuko Ohara-Nemoto
Yu Shimoyama
Gustavo Arruda Bezerra
Takayuki K Nemoto
P2860cites workDetermination of the genome sequence of Porphyromonas gingivalis strain ATCC 33277 and genomic comparison with strain W83 revealed extensive genome rearrangements in P. gingivalisQ22066058
One site mutation disrupts dimer formation in human DPP-IV proteinsQ24305361
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The acylaminoacyl peptidase from Aeropyrum pernix K1 thought to be an exopeptidase displays endopeptidase activityQ27644021
Structures of Human DPP7 Reveal the Molecular Basis of Specific Inhibition and the Architectural Diversity of Proline-Specific PeptidasesQ27672453
A Self-compartmentalizing Hexamer Serine Protease from Pyrococcus Horikoshii: SUBSTRATE SELECTION ACHIEVED THROUGH MULTIMERIZATIONQ27677875
Discrimination based on Gly and Arg/Ser at position 673 between dipeptidyl-peptidase (DPP) 7 and DPP11, widely distributed DPPs in pathogenic and environmental gram-negative bacteriaQ28485564
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Porphyromonas gingivalis DPP-7 represents a novel type of dipeptidylpeptidaseQ31629212
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Prevalence of Porphyromonas gingivalis and periodontal health statusQ33687844
Prolyl tripeptidyl peptidase from Porphyromonas gingivalis. A novel enzyme with possible pathological implications for the development of periodontitisQ33856227
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Emerging family of proline-specific peptidases of Porphyromonas gingivalis: purification and characterization of serine dipeptidyl peptidase, a structural and functional homologue of mammalian prolyl dipeptidyl peptidase IVQ34003494
Molecular cloning and structural characterization of the Arg-gingipain proteinase of Porphyromonas gingivalis. Biosynthesis as a proteinase-adhesin polyproteinQ34317271
The association between rheumatoid arthritis and periodontal diseaseQ34346150
The prolyl oligopeptidase familyQ34578122
Protease II from Escherichia coli: Sequencing and Expression of the Enzyme Gene and Characterization of the Expressed Enzyme1Q34663443
Porphyromonas gingivalis, Treponema denticola, and Tannerella forsythia: the "red complex", a prototype polybacterial pathogenic consortium in periodontitisQ36107786
Genome of the pathogen Porphyromonas gingivalis recovered from a biofilm in a hospital sink using a high-throughput single-cell genomics platformQ36800454
Putative respiratory chain of Porphyromonas gingivalisQ37742169
Scalable web services for the PSIPRED Protein Analysis Workbench.Q38420965
Asp- and Glu-specific novel dipeptidyl peptidase 11 of Porphyromonas gingivalis ensures utilization of proteinaceous energy sourcesQ38928970
Metabolic pathways for cytotoxic end product formation from glutamate- and aspartate-containing peptides by Porphyromonas gingivalisQ39587565
Butyrate and propionate: important components of toxic dental plaque extracts.Q40614579
Resolution of the multiplicity of the glutamate and aspartate transport systems of Escherichia coliQ40829335
Phenylalanine 664 of dipeptidyl peptidase (DPP) 7 and Phenylalanine 671 of DPP11 mediate preference for P2-position hydrophobic residues of a substrateQ41263799
Porphyromonas gingivalis outer membrane vesicles exclusively contain outer membrane and periplasmic proteins and carry a cargo enriched with virulence factorsQ41608941
Identification and characterization of prokaryotic dipeptidyl-peptidase 5 from Porphyromonas gingivalisQ41984188
Complete genome sequence of the bacterium Porphyromonas gingivalis TDC60, which causes periodontal disease.Q42120475
Does the importance of the C-terminal residues in the maturation of RgpB from Porphyromonas gingivalis reveal a novel mechanism for protein export in a subgroup of Gram-Negative bacteria?Q42957420
Crystal structure of an acylpeptide hydrolase/esterase from Aeropyrum pernix K1.Q43016205
Activation of oligopeptidase B from Streptomyces griseus by thiol-reacting reagents is independent of the single reactive cysteine residueQ43295738
Glycylprolyl dipeptidylaminopeptidase from Bacteroides gingivalisQ43642751
Preferential utilization of dipeptides by Porphyromonas gingivalisQ43661676
pGenTHREADER and pDomTHREADER: new methods for improved protein fold recognition and superfamily discriminationQ43796689
Purification and characterisation of a trypsin-like serine oligopeptidase from Trypanosoma congolense.Q46224745
Evidence for tissue-specific forms of glutaminyl cyclaseQ48148372
Effects of a bacterial lipid byproduct on human pulp fibroblasts in vitro.Q53565116
Amino Acid Transport Systems in Escherichia coli K12Q53760422
Purification and partial characterization of alpha-N-acylpeptide hydrolase from bovine liverQ67355657
Isolation and characterization of gingivain, a cysteine proteinase from Porphyromonas gingivalis strain W83Q68493659
Bacterial profiles of subgingival plaques in periodontitisQ69859706
Competition for peptides and amino acids among periodontal bacteriaQ70845621
Association of oral Bacteroides with gingivitis and adult periodontitisQ72509875
Relationship of sidechain hydrophobicity and alpha-helical propensity on the stability of the single-stranded amphipathic alpha-helixQ73510301
Genetic analyses of proteolysis, hemoglobin binding, and hemagglutination of Porphyromonas gingivalis. Construction of mutants with a combination of rgpA, rgpB, kgp, and hagAQ77863752
Antibodies to periodontal organisms are associated with decreased kidney function. The Dental Atherosclerosis Risk In Communities studyQ79434630
Crystal structure and mechanism of tripeptidyl activity of prolyl tripeptidyl aminopeptidase from Porphyromonas gingivalisQ80128008
Butyric acid induces apoptosis in inflamed fibroblastsQ80241588
Oral bacteria in the occluded arteries of patients with Buerger diseaseQ80361929
P433issue11
P407language of work or nameEnglishQ1860
P921main subjectPorphyromonas gingivalisQ3214147
P304page(s)5913-5925
P577publication date2016-01-05
P1433published inJournal of Biological ChemistryQ867727
P1476titleA Porphyromonas gingivalis Periplasmic Novel Exopeptidase, Acylpeptidyl Oligopeptidase, Releases N-Acylated Di- and Tripeptides from Oligopeptides
P478volume291

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cites work (P2860)
Q48255950Degradation of Incretins and Modulation of Blood Glucose Levels by Periodontopathic Bacterial Dipeptidyl Peptidase 4.
Q99565605Metabolic cooperativity between Porphyromonas gingivalis and Treponema denticola
Q94562979Structural and functional insights into oligopeptide acquisition by the RagAB transporter from Porphyromonas gingivalis

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