A combination of both arginine- and lysine-specific gingipain activity of Porphyromonas gingivalis is necessary for the generation of the micro-oxo bishaem-containing pigment from haemoglobin.

scientific article

A combination of both arginine- and lysine-specific gingipain activity of Porphyromonas gingivalis is necessary for the generation of the micro-oxo bishaem-containing pigment from haemoglobin. is …
instance of (P31):
scholarly articleQ13442814

External links are
P356DOI10.1042/BJ20031221
P932PMC publication ID1224116
P698PubMed publication ID14741050
P5875ResearchGate publication ID8904988

P50authorJack SilverQ56480316
P2093author name stringAndrew J Birss
John W Smalley
Michael F Thomas
Robert Withnall
P2860cites workThe atomic structure of human methemalbumin at 1.9 AQ27638056
The effects of heme-binding proteins on the peroxidative and catalatic activities of heminQ28141906
Mechanism of oxyhaemoglobin breakdown on reaction with acetylphenylhydrazineQ28321937
Porphyromonas gingivalis proteinases as virulence determinants in progression of periodontal diseasesQ33987592
Degradation of host heme proteins by lysine- and arginine-specific cysteine proteinases (gingipains) of Porphyromonas gingivalis.Q33996920
Variable carbohydrate modifications to the catalytic chains of the RgpA and RgpB proteases of Porphyromonas gingivalis W50.Q34001332
The role of gingipains in the pathogenesis of periodontal diseaseQ35068830
The multiple forms of trypsin-like activity present in various strains of Porphyromonas gingivalis are due to the presence of either Arg-gingipain or Lys-gingipainQ35397754
Hemoglobinase activity of the lysine gingipain protease (Kgp) of Porphyromonas gingivalis W83.Q39496808
Localization of HArep-containing genes on the chromosome of Porphyromonas gingivalis W83.Q39610718
Reactions involving superoxide and normal and unstable haemoglobinsQ40005648
The periodontopathogen Porphyromonas gingivalis binds iron protoporphyrin IX in the mu-oxo dimeric form: an oxidative buffer and possible pathogenic mechanismQ42115902
The catalase activity of ferrihaemsQ42557531
Cloning and sequencing of the gene encoding a novel lysine-specific cysteine proteinase (Lys-gingipain) in Porphyromonas gingivalis: structural relationship with the arginine-specific cysteine proteinase (Arg-gingipain).Q42642365
Catalatic activity of iron(III)-centred catalysts. Role of dimerization in the catalytic action of ferrihaemsQ42925458
Interactions of Porphyromonas gingivalis with oxyhaemoglobin and deoxyhaemoglobinQ43001056
Resonance Raman spectra of heme proteins. Effects of oxidation and spin stateQ43730365
The periodontal pathogen Porphyromonas gingivalis harnesses the chemistry of the mu-oxo bishaem of iron protoporphyrin IX to protect against hydrogen peroxide.Q43896377
Spectroscopic studies on human serum albumin and methemalbumin: optical, steady-state, and picosecond time-resolved fluorescence studies, and kinetics of substrate oxidation by methemalbuminQ43949234
Generation of lys-gingipain protease activity in Porphyromonas gingivalis W50 is independent of Arg-gingipain protease activitiesQ44006483
Microbial etiological agents of destructive periodontal diseasesQ44957526
Molecular cloning and characterization of Porphyromonas gingivalis lysine-specific gingipain. A new member of an emerging family of pathogenic bacterial cysteine proteinasesQ46086294
Involvement of a lysine-specific cysteine proteinase in hemoglobin adsorption and heme accumulation by Porphyromonas gingivalisQ47724105
The prpR1 and prR2 arginine-specific protease genes of Porphyromonas gingivalis W50 produce five biochemically distinct enzymesQ48053207
Studies on the stability of oxyhemoglobin A and its constituent chains and their derivatives.Q54764984
Arg-gingipain acts as a major processing enzyme for various cell surface proteins in Porphyromonas gingivalisQ64449894
Formation of hemichromes from oxidized hemoglobin subunitsQ68601619
The occurrence of Actinobacillus actinomycetemcomitans, Bacteroides gingivalis and Bacteroides intermedius in destructive periodontal disease in adultsQ68734468
The haem pigment of the oral anaerobes Prevotella nigrescens and Prevotella intermedia is composed of iron(III) protoporphyrin IX in the monomeric formQ73653531
Albumin and hemalbumin degradation by Porphyromonas gingivalisQ74188510
Iron protoporphyrin IX-albumin complexing increases the capacity and avidity of its binding to the periodontopathogen Porphyromonas gingivalisQ74629295
Genetic analyses of proteolysis, hemoglobin binding, and hemagglutination of Porphyromonas gingivalis. Construction of mutants with a combination of rgpA, rgpB, kgp, and hagAQ77863752
P433issuePt 3
P407language of work or nameEnglishQ1860
P921main subjectPorphyromonas gingivalisQ3214147
P1104number of pages8
P304page(s)833-840
P577publication date2004-05-01
P1433published inBiochemical JournalQ864221
P1476titleA combination of both arginine- and lysine-specific gingipain activity of Porphyromonas gingivalis is necessary for the generation of the micro-oxo bishaem-containing pigment from haemoglobin
P478volume379

Reverse relations

cites work (P2860)
Q31138714A two-component system regulates hemin acquisition in Porphyromonas gingivalis
Q33753638Antibacterial action of polyphosphate on Porphyromonas gingivalis
Q34401001Characterization of a Hemophore-like Protein from Porphyromonas gingivalis
Q34076596Dichotomy of gingipains action as virulence factors: from cleaving substrates with the precision of a surgeon's knife to a meat chopper-like brutal degradation of proteins.
Q38182102Gingipains from Porphyromonas gingivalis - Complex domain structures confer diverse functions
Q38668096Heme acquisition mechanisms of Porphyromonas gingivalis - strategies used in a polymicrobial community in a heme-limited host environment
Q42359429Hemin binding by Porphyromonas gingivalis strains is dependent on the presence of A-LPS.
Q33841960HmuY haemophore and gingipain proteases constitute a unique syntrophic system of haem acquisition by Porphyromonas gingivalis
Q36932089Mechanism of methaemoglobin breakdown by the lysine-specific gingipain of the periodontal pathogen Porphyromonas gingivalis
Q33675274Metal uptake in host-pathogen interactions: role of iron in Porphyromonas gingivalis interactions with host organisms
Q27001535Oxidative stress resistance in Porphyromonas gingivalis
Q36155466PG1058 Is a Novel Multidomain Protein Component of the Bacterial Type IX Secretion System
Q28547754Porphyromonas gingivalis Type IX Secretion Substrates Are Cleaved and Modified by a Sortase-Like Mechanism
Q26850410Porphyromonas gingivalis and related bacteria: from colonial pigmentation to the type IX secretion system and gliding motility
Q33509371Role of the cysteine protease interpain A of Prevotella intermedia in breakdown and release of haem from haemoglobin
Q35328858Sialidase and sialoglycoproteases can modulate virulence in Porphyromonas gingivalis
Q33321305Specific-wavelength visible light irradiation inhibits bacterial growth of Porphyromonas gingivalis
Q46247224Two-component signal transduction systems in oral bacteria
Q38070935VimA mediates multiple functions that control virulence in Porphyromonas gingivalis
Q35689547VimA-dependent modulation of acetyl coenzyme A levels and lipid A biosynthesis can alter virulence in Porphyromonas gingivalis

Search more.