Gary K Owens

researcher

Gary K Owens is …
instance of (P31):
humanQ5

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P214VIAF ID290937860

P734family nameOwensQ357139
OwensQ357139
OwensQ357139
P735given nameGaryQ1820274
GaryQ1820274
P106occupationresearcherQ1650915

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author (P50)
Q30274746"Attack of the Clones": Commonalities Between Cancer and Atherosclerosis
Q304358375' CArG degeneracy in smooth muscle alpha-actin is required for injury-induced gene suppression in vivo
Q273426595-Lipoxygenase pathway in experimental abdominal aortic aneurysms
Q30434820A G/C element mediates repression of the SM22alpha promoter within phenotypically modulated smooth muscle cells in experimental atherosclerosis.
Q30470837A new single-injury model of balloon angioplasty in cholesterol-fed rabbits: beneficial effect of hirudin and comparison with double-injury model
Q30464911A retinoic acid-induced clonal cell line derived from multipotential P19 embryonal carcinoma cells expresses smooth muscle characteristics
Q30470269A transforming growth factor beta (TGFbeta) control element drives TGFbeta-induced stimulation of smooth muscle alpha-actin gene expression in concert with two CArG elements
Q30311219A transforming growth factor-beta control element required for SM alpha-actin expression in vivo also partially mediates GKLF-dependent transcriptional repression
Q30434317ANG II type 2 receptor regulates smooth muscle growth and force generation in late fetal mouse development
Q30467577ANG II- or AVP-induced increases in protein synthesis are not dependent on autocrine secretion of PDGF-AA.
Q30464704Activated alpha 2-macroglobulin and transforming growth factor-beta 1 induce a synergistic smooth muscle cell proliferative response
Q30276803Activation of the pluripotency factor OCT4 in smooth muscle cells is atheroprotective
Q30412759Adenosine 2A receptor modulates inflammation and phenotype in experimental abdominal aortic aneurysms
Q56883827All-trans-retinoic acid limits restenosis after balloon angioplasty in the focally atherosclerotic rabbit : a favorable effect on vessel remodeling
Q30462210Angiotensin II induces hypertrophy, not hyperplasia, of cultured rat aortic smooth muscle cells
Q30467802Angiotensin II stimulates increased protein synthesis, not increased DNA synthesis, in intact rat aortic segments, in vitro
Q30464081Angiotensin II-induced hypertrophy of rat vascular smooth muscle is associated with increased 18 S rRNA synthesis and phosphorylation of the rRNA transcription factor, upstream binding factor
Q30434958Angiotensin II-induced mitogenesis of spontaneously hypertensive rat-derived cultured smooth muscle cells is dependent on autocrine production of transforming growth factor-beta
Q30471070Angiotensin II-induced stimulation of smooth muscle alpha-actin expression by serum response factor and the homeodomain transcription factor MHox
Q30469807Arterial thrombin activity after angioplasty in an atherosclerotic rabbit model: time course and effect of hirudin
Q30440172Assessment of contractility of purified smooth muscle cells derived from embryonic stem cells.
Q30419933Bone marrow-derived MCP1 required for experimental aortic aneurysm formation and smooth muscle phenotypic modulation
Q30434254Bone marrow-derived cell-specific chemokine (C-C motif) receptor-2 expression is required for arteriolar remodeling
Q30307166CArG elements control smooth muscle subtype-specific expression of smooth muscle myosin in vivo
Q47724846Cigarette Smoke Initiates Oxidative Stress-Induced Cellular Phenotypic Modulation Leading to Cerebral Aneurysm Pathogenesis
Q30417628Cigarette smoke modulates vascular smooth muscle phenotype: implications for carotid and cerebrovascular disease
Q96429533Clonally expanding smooth muscle cells promote atherosclerosis by escaping efferocytosis and activating the complement cascade
Q30310837Combinatorial Control of Smooth Muscle–Specific Gene Expression
Q30441798Concise review: epigenetic mechanisms contribute to pluripotency and cell lineage determination of embryonic stem cells
Q30440313Conditional deletion of Krüppel-like factor 4 delays downregulation of smooth muscle cell differentiation markers but accelerates neointimal formation following vascular injury
Q30442507Conditional mouse models to study developmental and pathophysiological gene function in muscle.
Q30439134Control of SRF binding to CArG box chromatin regulates smooth muscle gene expression in vivo.
Q30417509Cooperative binding of KLF4, pELK-1, and HDAC2 to a G/C repressor element in the SM22α promoter mediates transcriptional silencing during SMC phenotypic switching in vivo
Q27311289Coronary Artery Disease Associated Transcription Factor TCF21 Regulates Smooth Muscle Precursor Cells That Contribute to the Fibrous Cap
Q30279158Coronary Artery Disease Associated Transcription Factor TCF21 Regulates Smooth Muscle Precursor Cells that Contribute to the Fibrous Cap
Q42371429Corrigendum: KLF4-dependent phenotypic modulation of smooth muscle cells has a key role in atherosclerotic plaque pathogenesis
Q30413049Critical role of TNF-α in cerebral aneurysm formation and progression to rupture
Q39904340Derivation of contractile smooth muscle cells from embryonic stem cells.
Q30417984Detection of histone modifications at specific gene loci in single cells in histological sections
Q30306023Development of a smooth muscle-targeted cre recombinase mouse reveals novel insights regarding smooth muscle myosin heavy chain promoter regulation.
Q41474291Developmental changes in isoactin expression in rat aortic smooth muscle cells in vivo. Relationship between growth and cytodifferentiation
Q30460194Differential effect of platelet-derived growth factor- versus serum-induced growth on smooth muscle alpha-actin and nonmuscle beta-actin mRNA expression in cultured rat aortic smooth muscle cells
Q30472866Early plus delayed hirudin reduces restenosis in the atherosclerotic rabbit more than early administration alone: potential implications for dosing of antithrombin agents
Q30468424Effect of thrombin inhibition with desulfatohirudin on early kinetics of cellular proliferation after balloon angioplasty in atherosclerotic rabbits
Q30442965Elements of the smooth muscle alpha-actin promoter required in cis for transcriptional activation in smooth muscle. Evidence for cell type-specific regulation
Q28085153Epigenetic Control of Smooth Muscle Cell Identity and Lineage Memory
Q36449063Excitation-transcription coupling in arterial smooth muscle.
Q30470081Expression of the smooth muscle myosin heavy chain gene is regulated by a negative-acting GC-rich element located between two positive-acting serum response factor-binding elements
Q30433885Forced expression of myocardin is not sufficient for induction of smooth muscle differentiation in multipotential embryonic cells
Q100516888Genetic Regulation of Atherosclerosis-Relevant Phenotypes in Human Vascular Smooth Muscle Cells
Q30414961Genetic and pharmacologic disruption of interleukin-1β signaling inhibits experimental aortic aneurysm formation
Q30429015Genetic inactivation of IL-1 signaling enhances atherosclerotic plaque instability and reduces outward vessel remodeling in advanced atherosclerosis in mice
Q63915751Genetic inactivation of IL-1 signaling enhances atherosclerotic plaque instability and reduces outward vessel remodeling in advanced atherosclerosis in mice
Q54502831Hyperplastic growth response of vascular smooth muscle cells following induction of acute hypertension in rats by aortic coarctation.
Q30355344Inhibition of interleukin-1β decreases aneurysm formation and progression in a novel model of thoracic aortic aneurysms.
Q30471257Interaction of CArG elements and a GC-rich repressor element in transcriptional regulation of the smooth muscle myosin heavy chain gene in vascular smooth muscle cells
Q56340944Interleukin-1β has atheroprotective effects in advanced atherosclerotic lesions of mice
Q30421700Interleukin-1β modulates smooth muscle cell phenotype to a distinct inflammatory state relative to PDGF-DD via NF-κB-dependent mechanisms
Q56334440Irradiation abolishes smooth muscle investment into vascular lesions in specific vascular beds
Q100546201KLF4 (Kruppel-Like Factor 4)-Dependent Perivascular Plasticity Contributes to Adipose Tissue inflammation
Q30410765KLF4 regulates abdominal aortic aneurysm morphology and deletion attenuates aneurysm formation
Q45067616KLF4-dependent perivascular cell plasticity mediates pre-metastatic niche formation and metastasis
Q30299921KLF4-dependent phenotypic modulation of smooth muscle cells has a key role in atherosclerotic plaque pathogenesis
Q30435516Kruppel-like factor 4 abrogates myocardin-induced activation of smooth muscle gene expression.
Q28579612Kruppel-like factor 4, Elk-1, and histone deacetylases cooperatively suppress smooth muscle cell differentiation markers in response to oxidized phospholipids
Q30433980L-type voltage-gated Ca2+ channels modulate expression of smooth muscle differentiation marker genes via a rho kinase/myocardin/SRF-dependent mechanism.
Q30439147LPP expression during in vitro smooth muscle differentiation and stent-induced vascular injury
Q30304454Local adenovirus-mediated delivery of hirudin in a rabbit arterial injury model
Q30415442Loss of CDKN2B promotes p53-dependent smooth muscle cell apoptosis and aneurysm formation
Q30433459Lost in transdifferentiation.
Q30442406Mass spectrometric identification of phosphorylation sites of rRNA transcription factor upstream binding factor
Q30449270Mechanisms of angiotensin II- and arginine vasopressin-induced increases in protein synthesis and content in cultured rat aortic smooth muscle cells. Evidence for selective increases in smooth muscle isoactin expression
Q30438261Mobilization of bone marrow-derived cells enhances the angiogenic response to hypoxia without transdifferentiation into endothelial cells
Q30435971Molecular determinants of vascular smooth muscle cell diversity
Q30306339Molecular mechanisms of decreased smooth muscle differentiation marker expression after vascular injury.
Q30470362Molecular regulation of smooth muscle cell differentiation.
Q30441514Multiple repressor pathways contribute to phenotypic switching of vascular smooth muscle cells
Q30312218Myocardin and Prx1 contribute to angiotensin II-induced expression of smooth muscle alpha-actin
Q30310712Myocardin is a key regulator of CArG-dependent transcription of multiple smooth muscle marker genes
Q29347238Myocardin is differentially required for the development of smooth muscle cells and cardiomyocytes
Q30434723Myosin light chain kinase knockout
Q30467899Native and activated forms of alpha 2-macroglobulin increase expression of platelet-derived growth factor alpha-receptor in vascular smooth muscle cells. Evidence for autocrine transforming growth factor-beta activity
Q90908931Novel Autoimmune IgM Antibody Attenuates Atherosclerosis in IgM Deficient Low-Fat Diet-Fed, but Not Western Diet-Fed Apoe-/- Mice
Q46757550Nox1 overexpression potentiates angiotensin II-induced hypertension and vascular smooth muscle hypertrophy in transgenic mice
Q30465020Nuclear proteins bind a cis-acting element in the smooth muscle alpha-actin promoter
Q30277876Origin of Matrix-Producing Cells That Contribute to Aortic Fibrosis in Hypertension
Q79365777Origin of neointimal smooth muscle: we've come full circle
Q30435622Over-expression of the transcription factor, ZBP-89, leads to enhancement of the C2C12 myogenic program
Q30444292Oxidized phospholipids induce phenotypic switching of vascular smooth muscle cells in vivo and in vitro
Q30436774Oxidized phospholipids induce type VIII collagen expression and vascular smooth muscle cell migration
Q30437153PDGF-DD, a novel mediator of smooth muscle cell phenotypic modulation, is upregulated in endothelial cells exposed to atherosclerosis-prone flow patterns
Q28569320PIAS1 activates the expression of smooth muscle cell differentiation marker genes by interacting with serum response factor and class I basic helix-loop-helix proteins.
Q30427433PIAS1 mediates TGFbeta-induced SM alpha-actin gene expression through inhibition of KLF4 function-expression by protein sumoylation
Q28594760PRISM/PRDM6, a transcriptional repressor that promotes the proliferative gene program in smooth muscle cells.
Q28505500Pitx2 is functionally important in the early stages of vascular smooth muscle cell differentiation
Q91506735PlaqOmics Leducq Fondation Trans-Atlantic Network
Q44980179Platelet-derived growth factor regulates actin isoform expression and growth state in cultured rat aortic smooth muscle cells
Q30432867Platelet-derived growth factor-BB and Ets-1 transcription factor negatively regulate transcription of multiple smooth muscle cell differentiation marker genes
Q44923453Platelet-derived growth factor-BB represses smooth muscle cell marker genes via changes in binding of MKL factors and histone deacetylases to their promoters
Q30311540Platelet-derived growth factor-BB-induced suppression of smooth muscle cell differentiation
Q30455733Platelet-derived growth factor-induced destabilization of smooth muscle alpha-actin mRNA.
Q30305991Positive- and negative-acting Kruppel-like transcription factors bind a transforming growth factor beta control element required for expression of the smooth muscle cell differentiation marker SM22alpha in vivo.
Q52529960Predictors of luminal narrowing by neointima after angioplasty in atherosclerotic rabbits.
Q30443716Programming smooth muscle plasticity with chromatin dynamics
Q45048571Reconciling Smooth Muscle Cell Oligoclonality and Proliferative Capacity in Experimental Atherosclerosis
Q40800314Recruitment of serum response factor and hyperacetylation of histones at smooth muscle-specific regulatory regions during differentiation of a novel P19-derived in vitro smooth muscle differentiation system
Q30303899Regulation of smooth muscle alpha-actin expression in vivo is dependent on CArG elements within the 5' and first intron promoter regions
Q45011932Response to letter regarding article, "Inhibition of interleukin-1β decreases aneurysm formation and progression in a novel model of thoracic aortic aneurysm".
Q90271733Revealing the Origins of Foam Cells in Atherosclerotic Lesions
Q30464339Reversible permeabilization. A novel technique for the intracellular introduction of antisense oligodeoxynucleotides into intact smooth muscle
Q28203628Selective expression of an endogenous inhibitor of FAK regulates proliferation and migration of vascular smooth muscle cells
Q30253052Shifting the Focus of Preclinical, Murine Atherosclerosis Studies From Prevention to Late-Stage Intervention
Q30304262Similarities and differences in smooth muscle alpha-actin induction by TGF-beta in smooth muscle versus non-smooth muscle cells
Q30431496Smooth and cardiac muscle-selective knock-out of Kruppel-like factor 4 causes postnatal death and growth retardation
Q30304678Smooth muscle alpha-actin CArG elements coordinate formation of a smooth muscle cell-selective, serum response factor-containing activation complex
Q30310714Smooth muscle alpha-actin gene requires two E-boxes for proper expression in vivo and is a target of class I basic helix-loop-helix proteins
Q30418243Smooth muscle cell phenotypic switching in atherosclerosis
Q30411230Smooth muscle cell plasticity: fact or fiction?
Q30252988Smooth muscle cell-specific deletion of Col15a1 unexpectedly leads to impaired development of advanced atherosclerotic lesions
Q30444477Smooth muscle cells and myofibroblasts use distinct transcriptional mechanisms for smooth muscle alpha-actin expression
Q30306237Smooth muscle differentiation marker gene expression is regulated by RhoA-mediated actin polymerization
Q30439447Smooth muscle of telokin-deficient mice exhibits increased sensitivity to Ca2+ and decreased cGMP-induced relaxation
Q30434473Smooth muscle phenotypic modulation is an early event in aortic aneurysms
Q30472036Smooth muscle-specific expression of the smooth muscle myosin heavy chain gene in transgenic mice requires 5'-flanking and first intronic DNA sequence
Q30443089Smooth muscle-targeted knockout of connexin43 enhances neointimal formation in response to vascular injury
Q30436555Sp1-dependent activation of KLF4 is required for PDGF-BB-induced phenotypic modulation of smooth muscle
Q30440617Sphingosine-1-phosphate receptor subtypes differentially regulate smooth muscle cell phenotype
Q40347198Stem cells and their derivatives can bypass the requirement of myocardin for smooth muscle gene expression
Q30471918Substitution of the degenerate smooth muscle (SM) alpha-actin CC(A/T-rich)6GG elements with c-fos serum response elements results in increased basal expression but relaxed SM cell specificity and reduced angiotensin II inducibility
Q30410453TNF-α induces phenotypic modulation in cerebral vascular smooth muscle cells: implications for cerebral aneurysm pathology
Q45069046The CANTOS Trial: One Important Step for Clinical Cardiology but a Giant Leap for Vascular Biology
Q97568309The Stem Cell Pluripotency Genes Klf4 and Oct4 Regulate Complex SMC Phenotypic Changes Critical in Late-Stage Atherosclerotic Lesion Pathogenesis
Q30434710The actin associated protein palladin is important for the early smooth muscle cell differentiation
Q30437315The actin-associated protein Palladin is required for development of normal contractile properties of smooth muscle cells derived from embryoid bodies
Q30464808The smooth muscle alpha-actin gene promoter is differentially regulated in smooth muscle versus non-smooth muscle cells
Q30307689The smooth muscle myosin heavy chain gene exhibits smooth muscle subtype-selective modular regulation in vivo
Q30413885Therapeutic implications of estrogen for cerebral vasospasm and delayed cerebral ischemia induced by aneurysmal subarachnoid hemorrhage
Q30469144Thrombin and vascular smooth muscle cell proliferation: implications for atherosclerosis and restenosis
Q30449306Thrombin stimulates proliferation of cultured rat aortic smooth muscle cells by a proteolytically activated receptor
Q30465017Thrombin-induced mitogenesis in cultured aortic smooth muscle cells requires prolonged thrombin exposure
Q30466667Thrombin-induced mitogenesis of vascular SMC is partially mediated by autocrine production of PDGF-AA.
Q44904226Transforming growth factor-beta1 signaling contributes to development of smooth muscle cells from embryonic stem cells.
Q30457213Tumor necrosis factor-α modulates cerebral aneurysm formation and rupture
Q30277316Vascular Smooth Muscle Cells in Atherosclerosis
Q42484202Vascular hypertrophy in angiotensin II-induced hypertension is mediated by vascular smooth muscle cell-derived H2O2.
Q30457214Vascular smooth muscle cells in cerebral aneurysm pathogenesis
Q30426429WD repeat-containing protein 5, a ubiquitously expressed histone methyltransferase adaptor protein, regulates smooth muscle cell-selective gene activation through interaction with pituitary homeobox 2.
Q30418789Xenotropic MLV envelope proteins induce tumor cells to secrete factors that promote the formation of immature blood vessels.
Q90724359ZFP148 (Zinc-Finger Protein 148) Binds Cooperatively With NF-1 (Neurofibromin 1) to Inhibit Smooth Muscle Marker Gene Expression During Abdominal Aortic Aneurysm Formation
Q30470186alpha-Thrombin induces transforming growth factor-beta1 mRNA and protein in cultured vascular smooth muscle cells via a proteolytically activated receptor

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