The glycosylation in SARS-CoV-2 and its receptor ACE2

scholarly article by Yanqiu Gong published in November 2021

The glycosylation in SARS-CoV-2 and its receptor ACE2 is …
instance of (P31):
review articleQ7318358
scholarly articleQ13442814

External links are
P356DOI10.1038/S41392-021-00809-8
P932PMC publication ID8591162
P698PubMed publication ID34782609

P2093author name stringLunzhi Dai
Zhixin Tian
Yanqiu Gong
Suideng Qin
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Differentiating N-linked glycan structural isomers in metastatic and nonmetastatic tumor cells using sequential mass spectrometryQ37120207
Glycosylation analysis of glycoproteins and proteoglycans using capillary electrophoresis-mass spectrometry strategiesQ37177390
Boronic Acid-based approach for separation and immobilization of glycoproteins and its application in sensingQ37291380
Separation, detection and quantitation of peptides by liquid chromatography and capillary electrochromatographyQ37364856
Integrated Omics and Computational Glycobiology Reveal Structural Basis for Influenza A Virus Glycan Microheterogeneity and Host Interactions.Q37372252
Identification of Novel N-Glycosylation Sites at Noncanonical Protein Consensus MotifsQ37401444
N-linked glycosylation enrichment for in-depth cell surface proteomics of diffuse large B-cell lymphoma subtypesQ37428835
Vertebrate protein glycosylation: diversity, synthesis and functionQ37601831
A systematic approach to protein glycosylation analysis: a path through the mazeQ37790268
Structural basis of receptor recognition by SARS-CoV-2Q90738246
Structure of the SARS-CoV-2 spike receptor-binding domain bound to the ACE2 receptorQ90738260
COVID-19, ACE2, and the cardiovascular consequencesQ90757948
Virology, Epidemiology, Pathogenesis, and Control of COVID-19Q90773888
COVID-19, SARS and MERS: are they closely related?Q90799557
The role of galectins in virus infection - A systemic literature reviewQ90828681
Pharmacotherapy and adjunctive treatment for idiopathic pulmonary fibrosis (IPF)Q90839124
Advances in mass spectrometry-based glycoproteomicsQ91379582
Site- and structure-specific quantitative N-glycoproteomics study of differential N-glycosylation in MCF-7 cancer cellsQ91410936
Gal-3 is a potential biomarker for spinal cord injury and Gal-3 deficiency attenuates neuroinflammation through ROS/TXNIP/NLRP3 signaling pathwayQ91431725
High-throughput Serum N-Glycomics: Method Comparison and Application to Study Rheumatoid Arthritis and Pregnancy-associated ChangesQ91638315
SARS-CoV-2 Vaccines: Status ReportQ91662248
A Plant-Produced in vivo deglycosylated full-length Pfs48/45 as a Transmission-Blocking Vaccine Candidate against malariaQ91723010
Effects of Belapectin, an Inhibitor of Galectin-3, in Patients With Nonalcoholic Steatohepatitis With Cirrhosis and Portal HypertensionQ91776300
Natural antibodies - facts known and unknownQ91871967
A New Searching Strategy for the Identification of O-Linked GlycopeptidesQ91887207
Mapping human N-linked glycoproteins and glycosylation sites using mass spectrometryQ91934872
Coronaviruses and SARS-COV-2Q91953835
GlycopeptideGraphMS: Improved Glycopeptide Detection and Identification by Exploiting Graph Theoretical Patterns in Mass and Retention TimeQ91954789
Proteomics analysis of site-specific glycoforms by a virtual multistage mass spectrometry methodQ92133207
Cumulative Burden of Colorectal Cancer-Associated Genetic Variants Is More Strongly Associated With Early-Onset vs Late-Onset CancerQ92184158
GPSeeker Enables Quantitative Structural N-Glycoproteomics for Site- and Structure-Specific Characterization of Differentially Expressed N-Glycosylation in Hepatocellular CarcinomaQ92221737
Recent advances in glycoinformatic platforms for glycomics and glycoproteomicsQ92235926
Glyco-DIA: a method for quantitative O-glycoproteomics with in silico-boosted glycopeptide librariesQ92432902
Advances toward mapping the full extent of protein site-specific O-GalNAc glycosylation that better reflects underlying glycomic complexityQ92448534
Spontaneous Glycan Reattachment Following N-Glycanase Treatment of Influenza and HIV Vaccine AntigensQ92493535
Advances in hydrophilic nanomaterials for glycoproteomicsQ92633404
Glycosylation of viral surface proteins probed by mass spectrometryQ92766714
New Energy Setup Strategy for Intact N-Glycopeptides Characterization Using Higher-Energy Collisional DissociationQ92848186
Post-translational modification of baculovirus-encoded proteinsQ92975253
Enzymatic Release of Glycoprotein N-Glycans and Fluorescent LabelingQ93133579
The Architecture of SARS-CoV-2 TranscriptomeQ93208123
The trinity of COVID-19: immunity, inflammation and interventionQ94452368
Glycomics and glycoproteomics of viruses: Mass spectrometry applications and insights toward structure-function relationshipsQ94462993
A SARS-CoV-2 protein interaction map reveals targets for drug repurposingQ94470555
Deducing the N- and O- glycosylation profile of the spike protein of novel coronavirus SARS-CoV-2Q94503955
Site-specific glycan analysis of the SARS-CoV-2 spikeQ94520441
Rapid development of an inactivated vaccine candidate for SARS-CoV-2Q94589803
Cell entry mechanisms of SARS-CoV-2Q94589965
Potent neutralizing antibodies against SARS-CoV-2 identified by high-throughput single-cell sequencing of convalescent patients' B cellsQ95262934
Cross-neutralization of SARS-CoV-2 by a human monoclonal SARS-CoV antibodyQ95300582
Expression of the SARS-CoV-2 ACE2 Receptor in the Human Airway EpitheliumQ95304682
DNA vaccine protection against SARS-CoV-2 in rhesus macaquesQ95337677
Glycoinformatics approach for identifying target positions to inhibit initial binding of SARS-CoV-2 S1 protein to the host cellQ95605363
The cytokine storm in COVID-19: An overview of the involvement of the chemokine/chemokine-receptor systemQ95645944
Low collision energy fragmentation in structure-specific glycoproteomics analysisQ95646204
Optimal Dissociation Methods Differ for N- and O-glycopeptidesQ96160474
α-glucosidase inhibitors as host-directed antiviral agents with potential for the treatment of COVID-19Q96219633
Proteolytic Cleavage of the SARS-CoV-2 Spike Protein and the Role of the Novel S1/S2 SiteQ96225931
Protein glycosylation analysis by HILIC-LC-MS of Proteinase K-generated N- and O-glycopeptidesQ43133934
Synthesis of N-linked glycopeptides on solid support and their evaluation as protease substratesQ43156979
Investigations on the chromatographic behaviour of zwitterionic stationary phases used in hydrophilic interaction chromatographyQ43414844
Photodissociation of conformer-selected ubiquitin ions reveals site-specific cis/trans isomerization of proline peptide bondsQ43624959
A new strategy for identification of N-glycosylated proteins and unambiguous assignment of their glycosylation sites using HILIC enrichment and partial deglycosylation.Q44978166
The GlycanBuilder and GlycoWorkbench glycoinformatics tools: updates and new developmentsQ46156566
Use of multidimensional lectin affinity chromatography in differential glycoproteomicsQ46462285
Structure elucidation of native N- and O-linked glycans by tandem mass spectrometry (tutorial).Q46614544
HPLC-based analysis of serum N-glycans on a 96-well plate platform with dedicated database software.Q46808539
Analysis of mammalian O-glycopeptides -  we have made a good start, but there is a long way to go.Q46846034
Tools for glycoproteomic analysis: size exclusion chromatography facilitates identification of tryptic glycopeptides with N-linked glycosylation sitesQ46972135
Glycoproteins Enrichment and LC-MS/MS Glycoproteomics in Central Nervous System Applications.Q47153267
Top-Down Proteomics of Large Proteins up to 223 kDa Enabled by Serial Size Exclusion Chromatography StrategyQ47220928
Accurate phosphorylation site localization using phospho-bracketsQ47348158
Large-scale identification and visualization of N-glycans with primary structures using GlySeekerQ47379081
Exploiting the reversible covalent bonding of boronic acids: recognition, sensing, and assembly.Q47562366
Development of a data independent acquisition mass spectrometry workflow to enable glycopeptide analysis without predefined glycan compositional knowledge.Q47604730
Determination of site-specific glycan heterogeneity on glycoproteinsQ47650180
Microfluidic Capillary Electrophoresis-Mass Spectrometry for Analysis of Monosaccharides, Oligosaccharides, and GlycopeptidesQ48116778
Evaluation of Different N-Glycopeptide Enrichment Methods for N-Glycosylation Sites Mapping in Mouse BrainQ48592705
Glycoprotein Enrichment Analytical Techniques: Advantages and DisadvantagesQ49812897
N- and O-glycosylation analysis of human C1-inhibitor reveals extensive mucin-type O-glycosylationQ49886884
Investigation of O-glycosylation heterogeneity of recombinant coagulation factor IX using LC-MS/MS.Q50049635
Efficient and accurate glycopeptide identification pipeline for high-throughput site-specific N-glycosylation analysis.Q51091942
Fast, robust and high-resolution glycosylation profiling of intact monoclonal IgG antibodies using nanoLC-chip-QTOF.Q51457632
Global Aspects of Viral Glycosylation Enveloped viruses/herpesvirus/mass spectrometry/mucin type O-glycosylation/viral glycans.Q52341713
Global site-specific analysis of glycoprotein N-glycan processing.Q53068939
Beta 1-6 branching of Asn-linked oligosaccharides is directly associated with metastasis.Q53529803
Large-scale assignment of N-glycosylation sites using complementary enzymatic deglycosylation.Q54297336
Toward full peptide sequence coverage by dual fragmentation combining electron-transfer and higher-energy collision dissociation tandem mass spectrometry.Q55056794
Deciphering Protein O-Glycosylation: Solid-Phase Chemoenzymatic Cleavage and EnrichmentQ56349359
Characterization of glycosylation sites for a recombinant IgG1 monoclonal antibody and a CTLA4-Ig fusion protein by liquid chromatography-mass spectrometry peptide mappingQ56898429
Intact Human Alpha-Acid Glycoprotein (AGP) Analyzed by ESI-qTOF-MS: Simultaneous Determination of the Glycan Composition of Multiple Glycosylation SitesQ57181402
Rapid phenolic O-glycosylation of small molecules and complex unprotected peptides in aqueous solventQ57581070
The benefits of hybrid fragmentation methods for glycoproteomicsQ57665965
Crosstalk between phosphorylation and O-GlcNAcylation: friend or foeQ57665970
Glycosylation Site Analysis of Human Platelets by Electrostatic Repulsion Hydrophilic Interaction ChromatographyQ57842255
Unravelling the Role of O-glycans in Influenza A Virus InfectionQ58608748
Chemical Tagging in Mass Spectrometry for Systems BiologyQ58612613
Identification and Quantification of Protein GlycosylationQ58703048
Enzymatic Digestion and Mass Spectroscopies of N-Linked Glycans in Lacquer Stellacyanin fromRhus verniciferaQ59110781
Dopant Enriched Nitrogen Gas Combined with Sheathless Capillary Electrophoresis–Electrospray Ionization-Mass Spectrometry for Improved Sensitivity and Repeatability in Glycopeptide AnalysisQ60709652
Capturing site-specific heterogeneity with large-scale N-glycoproteome analysisQ64066959
Coronavirus envelope protein: current knowledgeQ64287253
Exploitation of glycosylation in enveloped virus pathobiologyQ64359271
Purified human anti-Tn and anti-T antibodies specifically recognize carcinoma tissues.Q64902298
Glycosylation in health and disease.Q64912085
Characterizing the selectivity of ER α-glucosidase inhibitors.Q64916951
Glycosylation of lipoprotein lipase in human subcutaneous and omental adipose tissuesQ68233145
Lectin affinity chromatography of glycopeptidesQ69076240
Glycan analysis by modern instrumental methodsQ37829419
From lectin structure to functional glycomics: principles of the sugar code.Q37860605
Stationary and mobile phases in hydrophilic interaction chromatography: a reviewQ37866441
Strategies for the profiling, characterisation and detailed structural analysis of N-linked oligosaccharidesQ38038071
Glycopeptide enrichment and separation for protein glycosylation analysis.Q38045258
N-glycoproteomics: mass spectrometry-based glycosylation site annotation.Q38048786
N-linked protein glycosylation in the ER.Q38098761
The use of sialidase therapy for respiratory viral infectionsQ38100493
Increasing the α 2, 6 sialylation of glycoproteins may contribute to metastatic spread and therapeutic resistance in colorectal cancerQ38169157
Interaction modes and approaches to glycopeptide and glycoprotein enrichmentQ38171227
Antibody signature induced by SARS-CoV-2 spike protein immunogens in rabbitsQ96230047
Cytokine Storm Induced by SARS-CoV-2Q96342930
Isomeric Separation of N-Glycopeptides Derived from Glycoproteins by Porous Graphitic Carbon (PGC) LC-MS/MSQ96437772
The ORF3a protein of SARS-CoV-2 induces apoptosis in cellsQ96576788
Open database searching enables the identification and comparison of bacterial glycoproteomes without defining glycan compositions prior to searchingQ96639231
A potential role for Galectin-3 inhibitors in the treatment of COVID-19Q96687334
Tracking changes in SARS-CoV-2 Spike: evidence that D614G increases infectivity of the COVID-19 virusQ96870819
Interactions of SARS-CoV-2 envelope protein with amilorides correlate with antiviral activityQ107134284
Simultaneous enrichment and separation of neutral and sialyl glycopeptides of SARS-CoV-2 spike protein enabled by dual-functionalized Ti-IMAC materialQ107329301
Glycosylation is a key in SARS-CoV-2 infectionQ107344131
Site-Specific O-Glycosylation Analysis of SARS-CoV-2 Spike Protein Produced in Insect and Human CellsQ107344366
How glycobiology can help us treat and beat the COVID-19 pandemicQ107349011
A COVID-19 Vaccine: Big Strides Come with Big ChallengesQ107349021
Glycans of SARS-CoV-2 Spike Protein in Virus Infection and Antibody ProductionQ107349422
Impact of Expressing Cells on Glycosylation and Glycan of the SARS-CoV-2 Spike GlycoproteinQ107377078
Glycosylation of SARS-CoV-2: structural and functional insightsQ107466751
Assessing Antigen Structural Integrity through Glycosylation Analysis of the SARS-CoV-2 Viral SpikeQ107466804
The Polybasic Cleavage Site in SARS-CoV-2 Spike Modulates Viral Sensitivity to Type I Interferon and IFITM2Q107473264
Heterogeneity of Glycan Processing on Trimeric SARS-CoV-2 Spike Protein Revealed by Charge Detection Mass SpectrometryQ108105033
Quantitative single-cell proteomics as a tool to characterize cellular hierarchiesQ108126951
Circulating SARS-CoV-2 spike N439K variants maintain fitness while evading antibody-mediated immunityQ108396862
Role of Structural and Non-Structural Proteins and Therapeutic Targets of SARS-CoV-2 for COVID-19Q109117104
P433issue1
P921main subjectprotein glycosylationQ14839643
SARS-CoV-2Q82069695
spike glycoprotein [SARS-CoV-2]Q87917585
Viroporin 3aQ88200603
envelope protein [SARS-CoV-2]Q88655710
membrane protein [SARS-CoV-2]Q88656821
P577publication date2021-11-15
P1433published inSignal Transduction and Targeted TherapyQ108821959
P1476titleThe glycosylation in SARS-CoV-2 and its receptor ACE2
P478volume6

Reverse relations

cites work (P2860)
Q101235543Maturation of spike protein
Q101210482Spike glycoprotein of SARS-CoV-2 binds ACE2 on host cell

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