| scholarly article | Q13442814 |
| P2093 | author name string | Theodore J Cory | |
| Russell S Emmons | |||
| Brandt D Pence | |||
| Johnathan R Yarbro | |||
| Kierstin L Davis | |||
| P2860 | cites work | Estimated costs of production and potential prices for the WHO Essential Medicines List. | Q53699577 |
| Respiratory Mononuclear Phagocytes in Human Influenza A Virus Infection: Their Role in Immune Protection and As Targets of the Virus. | Q55689281 | ||
| Monocytes and Macrophages as Viral Targets and Reservoirs | Q58723116 | ||
| Classical monocytes maintain ex vivo glycolytic metabolism and early but not later inflammatory responses in older adults | Q61443505 | ||
| Role of AMP-activated protein kinase in mechanism of metformin action | Q22241898 | ||
| Small molecule blockade of transcriptional coactivation of the hypoxia-inducible factor pathway | Q24299670 | ||
| Analysis of Relative Gene Expression Data Using Real-Time Quantitative PCR and the 2−ΔΔCT Method | Q25938999 | ||
| HIF-1alpha is essential for myeloid cell-mediated inflammation | Q29617581 | ||
| Succinate is an inflammatory signal that induces IL-1β through HIF-1α. | Q33652731 | ||
| Fatty Acid Oxidation Compensates for Lipopolysaccharide-Induced Warburg Effect in Glucose-Deprived Monocytes | Q33734714 | ||
| Metformin suppresses lipopolysaccharide (LPS)-induced inflammatory response in murine macrophages via activating transcription factor-3 (ATF-3) induction. | Q34044814 | ||
| Respiratory syncytial virus and asthma. The role of monocytes | Q34187153 | ||
| Dimethylbiguanide inhibits cell respiration via an indirect effect targeted on the respiratory chain complex I. | Q34506457 | ||
| Metformin suppresses hypoxia-induced stabilization of HIF-1α through reprogramming of oxygen metabolism in hepatocellular carcinoma | Q36729549 | ||
| NF-kappaB links innate immunity to the hypoxic response through transcriptional regulation of HIF-1alpha | Q37158836 | ||
| SARS coronavirus spike protein-induced innate immune response occurs via activation of the NF-kappaB pathway in human monocyte macrophages in vitro | Q37234254 | ||
| A guide to immunometabolism for immunologists. | Q38891307 | ||
| Tubular injury in a rat model of type 2 diabetes is prevented by metformin: a possible role of HIF-1α expression and oxygen metabolism | Q39599967 | ||
| Up-regulation of IL-6 and TNF-alpha induced by SARS-coronavirus spike protein in murine macrophages via NF-kappaB pathway | Q40127236 | ||
| HIF1α and metabolic reprogramming in inflammation. | Q41678886 | ||
| Metformin Inhibits the Production of Reactive Oxygen Species from NADH:Ubiquinone Oxidoreductase to Limit Induction of Interleukin-1β (IL-1β) and Boosts Interleukin-10 (IL-10) in Lipopolysaccharide (LPS)-activated Macrophages. | Q42248604 | ||
| Metformin, an antidiabetic agent, suppresses the production of tumor necrosis factor and tissue factor by inhibiting early growth response factor-1 expression in human monocytes in vitro | Q43108065 | ||
| Atypical monocytes in COVID-19: Lighting the fire of cytokine storm? | Q102204608 | ||
| Inflammasomes are activated in response to SARS-CoV-2 infection and are associated with COVID-19 severity in patients | Q102372236 | ||
| CD147-spike protein is a novel route for SARS-CoV-2 infection to host cells | Q104073430 | ||
| SARS-CoV-2-induced immune activation and death of monocyte-derived human macrophages and dendritic cells | Q104074607 | ||
| Scoring cytokine storm by the levels of MCP-3 and IL-8 accurately distinguished COVID-19 patients with high mortality | Q104471785 | ||
| Adherence Affects Monocyte Innate Immune Function and Metabolic Reprogramming after Lipopolysaccharide Stimulation In Vitro | Q104756562 | ||
| Loss of furin cleavage site attenuates SARS-CoV-2 pathogenesis | Q105098704 | ||
| Single-cell RNA sequencing reveals SARS-CoV-2 infection dynamics in lungs of African green monkeys | Q105516387 | ||
| COVID-19 immune features revealed by a large-scale single-cell transcriptome atlas | Q106315467 | ||
| TLR2 senses the SARS-CoV-2 envelope protein to produce inflammatory cytokines | Q107179972 | ||
| SARS-CoV-2 exacerbates proinflammatory responses in myeloid cells through C-type lectin receptors and Tweety family member 2 | Q107344282 | ||
| DC/L-SIGN recognition of spike glycoprotein promotes SARS-CoV-2 trans-infection and can be inhibited by a glycomimetic antagonist | Q107377319 | ||
| SARS-CoV-2 engages inflammasome and pyroptosis in human primary monocytes | Q108502925 | ||
| Evidence that metformin exerts its anti-diabetic effects through inhibition of complex 1 of the mitochondrial respiratory chain | Q110013094 | ||
| Metformin and risk of mortality in patients hospitalised with COVID-19: a retrospective cohort analysis | Q110013095 | ||
| Free SARS-CoV-2 Spike Protein S1 Particles May Play a Role in the Pathogenesis of COVID-19 Infection | Q110013096 | ||
| Major alterations in the mononuclear phagocyte landscape associated with COVID-19 severity | Q110013097 | ||
| Lipid droplets fuel SARS-CoV-2 replication and production of inflammatory mediators | Q110013098 | ||
| Metformin Use Is Associated With Reduced Mortality in a Diverse Population With COVID-19 and Diabetes | Q110013100 | ||
| Aging and monocyte immunometabolism in COVID-19 | Q110013101 | ||
| Metformin Suppresses Monocyte Immunometabolic Activation by SARS-CoV-2 and Spike Protein Subunit 1 | Q110013102 | ||
| Circulating SARS-CoV-2 Vaccine Antigen Detected in the Plasma of mRNA-1273 Vaccine Recipients | Q110013228 | ||
| Metformin inhibition of mitochondrial ATP and DNA synthesis abrogates NLRP3 inflammasome activation and pulmonary inflammation | Q110013229 | ||
| Monocytes and macrophages, targets of SARS-CoV-2: the clue for Covid-19 immunoparalysis | Q110013230 | ||
| Cellular events of acute, resolving or progressive COVID-19 in SARS-CoV-2 infected non-human primates | Q110013232 | ||
| Nucleocapsid and Spike Proteins of the Coronavirus SARS-CoV-2 Induce IL6 in Monocytes and Macrophages-Potential Implications for Cytokine Storm Syndrome | Q110013233 | ||
| The species Severe acute respiratory syndrome-related coronavirus: classifying 2019-nCoV and naming it SARS-CoV-2 | Q87000965 | ||
| Aging impairs mitochondrial respiratory capacity in classical monocytes | Q88360929 | ||
| Clinical and immunological features of severe and moderate coronavirus disease 2019 | Q90690744 | ||
| Metformin relieves acute respiratory distress syndrome by reducing miR-138 expression | Q91280316 | ||
| 2-Deoxy-d-Glucose and Its Analogs: From Diagnostic to Therapeutic Agents | Q92442029 | ||
| Tissue-Resident Alveolar Macrophages Do Not Rely on Glycolysis for LPS-induced Inflammation | Q93010695 | ||
| Complex Immune Dysregulation in COVID-19 Patients with Severe Respiratory Failure | Q93153123 | ||
| Classical monocytes from older adults maintain capacity for metabolic compensation during glucose deprivation and lipopolysaccharide stimulation | Q93165923 | ||
| The pathogenicity of SARS-CoV-2 in hACE2 transgenic mice | Q94148699 | ||
| Single-cell landscape of bronchoalveolar immune cells in patients with COVID-19 | Q94600823 | ||
| Clinical Characteristics and Outcomes of Patients With Diabetes and COVID-19 in Association With Glucose-Lowering Medication | Q94685427 | ||
| Imbalanced Host Response to SARS-CoV-2 Drives Development of COVID-19 | Q94687906 | ||
| Clinical and pathological investigation of severe COVID-19 patients | Q95297460 | ||
| SARS-CoV-2 infection protects against rechallenge in rhesus macaques | Q95337712 | ||
| Pathogenesis and transmission of SARS-CoV-2 in golden hamsters | Q95644306 | ||
| Metformin Treatment Was Associated with Decreased Mortality in COVID-19 Patients with Diabetes in a Retrospective Analysis | Q95644914 | ||
| Phenotypic characteristics and prognosis of inpatients with COVID-19 and diabetes: the CORONADO study | Q96023320 | ||
| Distribution of ACE2, CD147, CD26 and other SARS-CoV-2 associated molecules in tissues and immune cells in health and in asthma, COPD, obesity, hypertension, and COVID-19 risk factors | Q96118495 | ||
| Severe COVID-19 and aging: are monocytes the key? | Q96582171 | ||
| Pathological Findings of Postmortem Biopsies From Lung, Heart, and Liver of 7 Deceased COVID-19 Patients | Q96582203 | ||
| Attenuated interferon and pro-inflammatory response in SARS-CoV-2-infected human dendritic cells is associated with viral antagonism of STAT1 phosphorylation | Q96614445 | ||
| Infection with novel coronavirus (SARS-CoV-2) causes pneumonia in Rhesus macaques | Q97418600 | ||
| Immunological and inflammatory profiles in mild and severe cases of COVID-19 | Q97533294 | ||
| Elevated Glucose Levels Favor SARS-CoV-2 Infection and Monocyte Response through a HIF-1α/Glycolysis-Dependent Axis | Q97650503 | ||
| Early IL-1 receptor blockade in severe inflammatory respiratory failure complicating COVID-19 | Q97652653 | ||
| Longitudinal analyses reveal immunological misfiring in severe COVID-19 | Q97896835 | ||
| Single-cell analysis of two severe COVID-19 patients reveals a monocyte-associated and tocilizumab-responding cytokine storm | Q98237874 | ||
| Delayed severe cytokine storm and immune cell infiltration in SARS-CoV-2-infected aged Chinese rhesus macaques | Q98284996 | ||
| Mismatch between circulating cytokines and spontaneous cytokine production by leukocytes in hyperinflammatory COVID-19 | Q98467941 | ||
| A dynamic COVID-19 immune signature includes associations with poor prognosis | Q98513784 | ||
| Severe COVID-19 Is Marked by a Dysregulated Myeloid Cell Compartment | Q98563108 | ||
| SARS-CoV-2 infection of human ACE2-transgenic mice causes severe lung inflammation and impaired function | Q98665285 | ||
| An inflammatory cytokine signature predicts COVID-19 severity and survival | Q98665305 | ||
| Metformin use is associated with reduced mortality rate from coronavirus disease 2019 (COVID-19) infection | Q98727138 | ||
| Longitudinal immune profiling reveals key myeloid signatures associated with COVID-19 | Q99564461 | ||
| Metformin Is Associated with Higher Incidence of Acidosis, but Not Mortality, in Individuals with COVID-19 and Pre-existing Type 2 Diabetes | Q99622755 | ||
| Two distinct immunopathological profiles in autopsy lungs of COVID-19 | Q100503838 | ||
| Unique immunological profile in patients with COVID-19 | Q100636018 | ||
| Human Hematopoietic Stem, Progenitor, and Immune Cells Respond Ex Vivo to SARS-CoV-2 Spike Protein | Q100765115 | ||
| The differential immune responses to COVID-19 in peripheral and lung revealed by single-cell RNA sequencing | Q100992511 | ||
| SARS-CoV-2 membrane glycoprotein M antagonizes the MAVS-mediated innate antiviral response | Q101038989 | ||
| Single-Cell Transcriptome Analysis Highlights a Role for Neutrophils and Inflammatory Macrophages in the Pathogenesis of Severe COVID-19 | Q101159101 | ||
| Multi-Omics Resolves a Sharp Disease-State Shift between Mild and Moderate COVID-19 | Q101559148 | ||
| A Longitudinal Study of Immune Cells in Severe COVID-19 Patients | Q101575484 | ||
| P275 | copyright license | Creative Commons Attribution 4.0 International | Q20007257 |
| P6216 | copyright status | copyrighted | Q50423863 |
| P407 | language of work or name | English | Q1860 |
| P921 | main subject | metformin | Q19484 |
| pharmacology | Q128406 | ||
| SARS-CoV-2 | Q82069695 | ||
| spike glycoprotein [SARS-CoV-2] | Q87917585 | ||
| P304 | page(s) | 733921 | |
| P577 | publication date | 2021-01-01 | |
| P1433 | published in | Frontiers in Immunology | Q27723748 |
| P1476 | title | Metformin Suppresses Monocyte Immunometabolic Activation by SARS-CoV-2 Spike Protein Subunit 1 | |
| P478 | volume | 12 |
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