Erich Nigg

Swiss cell biologist

DBpedia resource is: http://dbpedia.org/resource/Erich_Nigg

Abstract is: Erich Nigg (born 28 November 1952 in Uster) is a Swiss cell biologist.

Wikimedia Commons category is Erich Nigg

Born 1952-11-28 in Uster (Q64032)

Erich Nigg is …
instance of (P31):
humanQ5

External links are
P6231BDELIS ID80051
P268Bibliothèque nationale de France ID146016537
P11496CiNii Research ID1140845216625853312
P8168FactGrid item IDQ886574
P646Freebase ID/m/0w7p_zx
P4872GEPRIS person ID1646417
P227GND ID172290716
P1960Google Scholar author IDXKwAiVsAAAAJ
P269IdRef ID081583834
P213ISNI0000000044573047
P10299Leopoldina member ID (new)erich-a-nigg
P3413Leopoldina member ID (superseded)1128
P244Library of Congress authority IDnb2004303253
P271NACSIS-CAT author IDDA1532889X
P8189National Library of Israel J9U ID987007319849005171
P1006Nationale Thesaurus voor Auteursnamen ID291346472
P1015NORAF ID90247563
P496ORCID iD0000-0003-4835-5719
P3368Prabook ID484733
P2038ResearchGate profile IDErich-Nigg
P1153Scopus author ID35433130400
P10013SNSF person ID3507
P214VIAF ID64256255
3250155044911772520009
P10832WorldCat Entities IDE39PBJyxm7mvYhGb9V3bxqxJjC

P166award receivedMeyenburg PrizeQ1926301
EMBO MembershipQ26268243
P27country of citizenshipSwitzerlandQ39
P69educated atUniversity of BaselQ372608
University of GenevaQ503473
University of California, San DiegoQ622664
P108employerBiozentrum University of BaselQ864916
University of GenevaQ503473
P734family nameNiggQ37326529
NiggQ37326529
NiggQ37326529
P735given nameErichQ15277196
ErichQ15277196
P463member ofGerman Academy of Sciences LeopoldinaQ543804
Academia EuropaeaQ337234
P106occupationuniversity teacherQ1622272
biochemistQ2919046
P21sex or gendermaleQ6581097

Reverse relations

author (P50)
Q364254993D-structured illumination microscopy provides novel insight into architecture of human centrosomes
Q36310555A bacterial type III secretion-based protein delivery tool for broad applications in cell biology
Q24320294A centrosomal function for the human Nek2 protein kinase, a member of the NIMA family of cell cycle regulators.
Q24540212A complex of two centrosomal proteins, CAP350 and FOP, cooperates with EB1 in microtubule anchoring
Q57985118A licence for duplication
Q28569992A mammalian RNA polymerase II holoenzyme containing all components required for promoter-specific transcription initiation
Q57985215A monoclonal antibody specific for snRNPs U1 and U2
Q39285846Acentrosomal spindle organization renders cancer cells dependent on the kinesin HSET.
Q24338617Active cyclin B1-Cdk1 first appears on centrosomes in prophase
Q35464261Assembly and cell cycle dynamics of the nuclear lamina
Q35978070Assembly-disassembly of the nuclear lamina
Q36133388Assessment of current mass spectrometric workflows for the quantification of low abundant proteins and phosphorylation sites
Q39754221Astrin is required for the maintenance of sister chromatid cohesion and centrosome integrity
Q35839779Aurora B controls kinetochore-microtubule attachments by inhibiting Ska complex-KMN network interaction
Q37104871Aurora B suppresses microtubule dynamics and limits central spindle size by locally activating KIF4A
Q35756009Aurora kinases link chromosome segregation and cell division to cancer susceptibility
Q24536196Aurora-A overexpression reveals tetraploidization as a major route to centrosome amplification in p53-/- cells
Q28202615Aurora-B phosphorylates Histone H3 at serine28 with regard to the mitotic chromosome condensation
Q28216339Aurora-B regulates the cleavage furrow-specific vimentin phosphorylation in the cytokinetic process
Q34361195Aurora-C kinase is a novel chromosomal passenger protein that can complement Aurora-B kinase function in mitotic cells
Q57985233Band 3-glycophorin A association in erythrocyte membranes demonstrated by combining protein diffusion measurements with antibody-induced cross-linking
Q35597296Biogenesis of the nuclear lamina: in vivo synthesis and processing of nuclear protein precursors.
Q24676678Borealin: a novel chromosomal passenger required for stability of the bipolar mitotic spindle
Q30667283Bub1 autophosphorylation feeds back to regulate kinetochore docking and promote localized substrate phosphorylation
Q30648730C-Nap1 mutation affects centriole cohesion and is associated with a Seckel-like syndrome in cattle.
Q57985125Calcium triggers exit from meiosis II by targeting the APC/C inhibitor XErp1 for degradation
Q34455814Cdk1/Erk2- and Plk1-dependent phosphorylation of a centrosome protein, Cep55, is required for its recruitment to midbody and cytokinesis.
Q36727037Cell cycle analysis and chromosomal localization of human Plk1, a putative homologue of the mitotic kinases Drosophila polo and Saccharomyces cerevisiae Cdc5.
Q47068857Cell cycle regulation of central spindle assembly.
Q24306123Cell cycle-dependent expression of Nek2, a novel human protein kinase related to the NIMA mitotic regulator of Aspergillus nidulans
Q42051639Cell cycle-regulated phosphorylation of the Xenopus polo-like kinase Plx1.
Q40939219Cell cycle. The NIMA kinase joins forces with Cdc2.
Q39393625Cell-cycle-regulated expression of STIL controls centriole number in human cells
Q57985194Cellular substrates of p34cdc2 and its companion cyclin-dependent kinases
Q39741611Centromere DNA decatenation depends on cohesin removal and is required for mammalian cell division
Q24547361Centromere targeting of the chromosomal passenger complex requires a ternary subcomplex of Borealin, Survivin, and the N-terminal domain of INCENP
Q34157650Centrosome aberrations: cause or consequence of cancer progression?
Q33880083Centrosome duplication in mammalian somatic cells requires E2F and Cdk2-cyclin A.
Q36769585Centrosome duplication: of rules and licenses
Q24301325Centrosome-associated Chk1 prevents premature activation of cyclin-B-Cdk1 kinase
Q42830689Centrosome-associated NDR kinase regulates centrosome duplication
Q33959927Centrosomes as signalling centres
Q33925659Cep164 triggers ciliogenesis by recruiting Tau tubulin kinase 2 to the mother centriole
Q24298367Cep164, a novel centriole appendage protein required for primary cilium formation
Q24301594Cep68 and Cep215 (Cdk5rap2) are required for centrosome cohesion
Q36530128Characterization of A 54-kD protein of the inner nuclear membrane: evidence for cell cycle-dependent interaction with the nuclear lamina
Q24299765Choice of Plk1 docking partners during mitosis and cytokinesis is controlled by the activation state of Cdk1
Q42165279Comparative conservation analysis of the human mitotic phosphoproteome
Q28288825Complex formation of Plk1 and INCENP required for metaphase-anaphase transition
Q39845210Control of centriole length by CPAP and CP110.
Q33823332Coordinate regulation of the mother centriole component nlp by nek2 and plk1 protein kinases
Q57985223Cyclic-AMP-dependent protein kinase type II is associated with the Golgi complex and with centrosomes
Q31107812Cyclin B2 undergoes cell cycle-dependent nuclear translocation and, when expressed as a non-destructible mutant, causes mitotic arrest in HeLa cells.
Q41066914Cyclin-dependent kinase 7: at the cross-roads of transcription, DNA repair and cell cycle control?
Q57985227Cytoskeletal targets for viral transforming proteins with tyrosine protein kinase activity
Q36428823Cytostatic factor: an activity that puts the cell cycle on hold
Q43207732Depletion of licensing inhibitor geminin causes centrosome overduplication and mitotic defects
Q41916004Different Plk1 functions show distinct dependencies on Polo-Box domain-mediated targeting
Q36217953Differential expression of nuclear lamin proteins during chicken development
Q35921144Differential phosphorylation of vertebrate p34cdc2 kinase at the G1/S and G2/M transitions of the cell cycle: identification of major phosphorylation sites
Q57985234Dimeric association of band 3 in the erythrocyte membrane demonstrated by protein diffusion measurements
Q54533856Direct regulation of tRNA and 5S rRNA gene transcription by Polo-like kinase 1.
Q37380380Drosophila Cdk8, a kinase partner of cyclin C that interacts with the large subunit of RNA polymerase II.
Q41295372Dynamic changes in nuclear architecture during mitosis: on the role of protein phosphorylation in spindle assembly and chromosome segregation.
Q41150191Ectopic expression of an A-type lamin does not interfere with differentiation of lamin A-negative embryonal carcinoma cells
Q38390854Evaluation and Improvement of Quantification Accuracy in Isobaric Mass Tag-Based Protein Quantification Experiments
Q30862966Evaluation of data-dependent and -independent mass spectrometric workflows for sensitive quantification of proteins and phosphorylation sites
Q24682520Exploring the functional interactions between Aurora B, INCENP, and survivin in mitosis
Q33524450From proteome lists to biological impact--tools and strategies for the analysis of large MS data sets
Q57277601GFP tagging reveals human Polo-like kinase 1 at the kinetochore/centromere region of mitotic chromosomes
Q57985122Geminin Regulates Multiple Steps of the Chromosome Inheritance Cycle
Q57985121HURP Is a Ran-Importin β-Regulated Protein that Stabilizes Kinetochore Microtubules in the Vicinity of Chromosomes
Q24292479Human Asf1 and CAF-1 interact and synergize in a repair-coupled nucleosome assembly pathway
Q44538474Human Cep192 and Cep152 cooperate in Plk4 recruitment and centriole duplication
Q24536263Human Mps1 kinase is required for the spindle assembly checkpoint but not for centrosome duplication
Q24671169Human TPX2 is required for targeting Aurora-A kinase to the spindle
Q24298560Human Tousled like kinases are targeted by an ATM- and Chk1-dependent DNA damage checkpoint
Q34729343Identification of a novel vertebrate cyclin: cyclin B3 shares properties with both A- and B-type cyclins.
Q24311956Identification of human cyclin-dependent kinase 8, a putative protein kinase partner for cyclin C
Q57985211Identification of major nucleolar proteins as candidate mitotic substrates of cdc2 kinase
Q44222981Identification of phosphorylation sites in the polo-like kinases Plx1 and Plk1 by a novel strategy based on element and electrospray high resolution mass spectrometry
Q36207378Immunofluorescent localization of a 39,000-dalton substrate of tyrosine protein kinases to the cytoplasmic surface of the plasma membrane.
Q36310517Immunofluorescent localization of the transforming protein of Rous sarcoma virus with antibodies against a synthetic src peptide
Q37373363Immunological characterization of avian MAP kinases: evidence for nuclear localization
Q57985119Influence of human Ect2 depletion and overexpression on cleavage furrow formation and abscission
Q45802695Influence of influenza and Sendai virus on the rotational mobility of Band 3 proteins in human erythrocyte membranes.
Q40250728Influence of temperature and cholesterol on the rotational diffusion of band 3 in the human erythrocyte membrane
Q57985131Inhibition of Centrosome Separation after DNA Damage: A Role for Nek2
Q43645744Isoprenylation of rab proteins on structurally distinct cysteine motifs.
Q24301784KIF14 and citron kinase act together to promote efficient cytokinesis
Q28270371Kinetochore localization and microtubule interaction of the human spindle checkpoint kinase Mps1
Q40196310Labeling of human erythrocyte membranes with eosin probes used for protein diffusion measurements. Inhibition of anion transport and photo-oxidative inactivation of acetylcholinesterase
Q40289655M-phase MELK activity is regulated by MPF and MAPK.
Q37623860MAT1 ('menage à trois') a new RING finger protein subunit stabilizing cyclin H-cdk7 complexes in starfish and Xenopus CAK.
Q24563127MAT1, cdk7 and cyclin H form a kinase complex which is UV light-sensitive upon association with TFIIH
Q57985205Mitogen-activated protein kinases phosphorylate nuclear lamins and display sequence specificity overlapping that of mitotic protein kinase p34cdc2
Q24314268Mitotic control of kinetochore-associated dynein and spindle orientation by human Spindly
Q24320475Molecular basis of tubulin transport within the cilium by IFT74 and IFT81.
Q35933396Mutations of p34cdc2 phosphorylation sites induce premature mitotic events in HeLa cells: evidence for a double block to p34cdc2 kinase activation in vertebrates
Q24296940Novel asymmetrically localizing components of human centrosomes identified by complementary proteomics methods
Q49136533Nuclear export of proteins: the role of nuclear retention.
Q36663596Nuclear import-export: in search of signals and mechanisms.
Q48098747Nuclear localization of vertebrate cyclin A correlates with its ability to form complexes with cdk catalytic subunits.
Q57985219Nuclear substructure antigens
Q36410448Oligosaccharide motion in erythrocyte membranes investigated by picosecond fluorescence polarization and microsecond dichroism of an optical probe
Q57985173On the Regulation and Function of Human Polo-like Kinase 1 (PLK1): Effects of Overexpression on Cell Cycle Progression
Q36314222On the nature of crossreactions observed with antibodies directed to defined epitopes.
Q30521431On the regulation, function, and localization of the DNA-dependent ATPase PICH.
Q36611139Origins and consequences of centrosome aberrations in human cancers
Q30540402PI 3-kinase-dependent phosphorylation of Plk1-Ser99 promotes association with 14-3-3γ and is required for metaphase-anaphase transition
Q27317132PICH promotes sister chromatid disjunction and co-operates with topoisomerase II in mitosis
Q34600951PICH, a centromere-associated SNF2 family ATPase, is regulated by Plk1 and required for the spindle checkpoint
Q34366324PICH: a DNA translocase specially adapted for processing anaphase bridge DNA.
Q42007577Persistence of DNA threads in human anaphase cells suggests late completion of sister chromatid decatenation
Q24547339Phosphoproteome analysis of the human mitotic spindle
Q40356177Phosphorylation by Cdk1 induces Plk1-mediated vimentin phosphorylation during mitosis
Q28244586Phosphorylation by p34cdc2 protein kinase regulates binding of the kinesin-related motor HsEg5 to the dynactin subunit p150
Q24315026Phosphorylation by p34cdc2 regulates spindle association of human Eg5, a kinesin-related motor essential for bipolar spindle formation in vivo
Q34463532Phosphorylation of Nlp by Plk1 negatively regulates its dynein-dynactin-dependent targeting to the centrosome
Q24317964Phosphorylation of mitotic kinesin-like protein 2 by polo-like kinase 1 is required for cytokinesis
Q38859208Plk1 and Mps1 Cooperatively Regulate the Spindle Assembly Checkpoint in Human Cells
Q24318919Plk1 regulates mitotic Aurora A function through betaTrCP-dependent degradation of hBora
Q34118510Plk4 trans-autophosphorylation regulates centriole number by controlling betaTrCP-mediated degradation
Q24336451Plk4-induced centriole biogenesis in human cells
Q28612103Polo-like kinase 1 regulates Nlp, a centrosome protein involved in microtubule nucleation
Q57985159Polo-like kinase-1 is a target of the DNA damage checkpoint
Q29616759Polo-like kinases and the orchestration of cell division
Q54442512Polo-like kinases.
Q34663706Polo-like kinases: positive regulators of cell division from start to finish.
Q36624591Probing the catalytic functions of Bub1 kinase using the small molecule inhibitors BAY-320 and BAY-524.
Q24315748Probing the in vivo function of Mad1:C-Mad2 in the spindle assembly checkpoint
Q41001831Protein kinases in the control of mitosis: focus on nucleocytoplasmic trafficking.
Q56904099Protein localization to the nucleolus: a search for targeting domains in nucleolin
Q24316321Proteome analysis of the human mitotic spindle
Q24301045Proteomic characterization of the human centrosome by protein correlation profiling
Q46847591Purification of mitotic spindles from cultured human cells
Q37307416Quantitative analysis of human centrosome architecture by targeted proteomics and fluorescence imaging.
Q43289758Quantitative analysis of the human spindle phosphoproteome at distinct mitotic stages
Q28477755Quantitative mass spectrometry analysis reveals similar substrate consensus motif for human Mps1 kinase and Plk1
Q24294864Quantitative phosphoproteomics reveals widespread full phosphorylation site occupancy during mitosis
Q39907130Quantitative site-specific phosphorylation dynamics of human protein kinases during mitotic progression
Q37035146RanBP2 and SENP3 function in a mitotic SUMO2/3 conjugation-deconjugation cycle on Borealin
Q35012285Re-examination of siRNA specificity questions role of PICH and Tao1 in the spindle checkpoint and identifies Mad2 as a sensitive target for small RNAs
Q34044967Regulating centrosomes by protein phosphorylation.
Q35591745Regulation of Aurora-A kinase on the mitotic spindle
Q35095547Regulation of cell division: stop the SIN!
Q35657748Regulation of p34cdc2 protein kinase activity by phosphorylation and cyclin binding.
Q24676654Relocation of Aurora B from centromeres to the central spindle at the metaphase to anaphase transition requires MKlp2
Q28204299Role of Hec1 in spindle checkpoint signaling and kinetochore recruitment of Mad1/Mad2
Q24337615Rootletin forms centriole-associated filaments and functions in centrosome cohesion
Q39586027Rotational diffusion of band 3 in the red cell membrane: measurements using triplet probes
Q57985231Rotational diffusion of band 3 proteins in membranes from En(a—) and neuraminidase-treated normal human erythrocytes
Q40312216Rotational diffusion of erythrocyte membrane proteins.
Q35933358STIL binding to Polo-box 3 of PLK4 regulates centriole duplication
Q41930712STIL microcephaly mutations interfere with APC/C-mediated degradation and cause centriole amplification
Q50336140SUMO-dependent regulation of centrin-2.
Q24537151Sgt1 is required for human kinetochore assembly
Q31132227Signal transduction. Capturing polo kinase
Q27343797Ska3 Ensures Timely Mitotic Progression by Interacting Directly With Microtubules and Ska1 Microtubule Binding Domain.
Q30414432Spatial exclusivity combined with positive and negative selection of phosphorylation motifs is the basis for context-dependent mitotic signaling
Q24314703Stable kinetochore-microtubule interactions depend on the Ska complex and its new component Ska3/C13Orf3.
Q24290949Strong functional interactions of TFIIH with XPC and XPG in human DNA nucleotide excision repair, without a preassembled repairosome
Q27678365Structural and functional organization of the Ska complex, a key component of the kinetochore-microtubule interface
Q27681275Structural basis for microtubule recognition by the human kinetochore Ska complex
Q36970336Structural centrosome aberrations favor proliferation by abrogating microtubule-dependent tissue integrity of breast epithelial mammospheres
Q52641939Structural centrosome aberrations promote non-cell-autonomous invasiveness.
Q57985050Structural centrosome aberrations sensitize polarized epithelia to basal cell extrusion
Q24298466Structure of a Survivin-Borealin-INCENP core complex reveals how chromosomal passengers travel together
Q24337012Structure of the N-terminal domain of the FOP (FGFR1OP) protein and implications for its dimerization and centrosomal localization
Q42066299Substrate specificity and cell cycle regulation of the Nek2 protein kinase, a potential human homolog of the mitotic regulator NIMA of Aspergillus nidulans.
Q28204964Suppression of Tousled-like kinase activity after DNA damage or replication block requires ATM, NBS1 and Chk1
Q35378544Targeting lamin proteins to the nuclear envelope: the role of CaaX box modifications.
Q40914611Targets of cyclin-dependent protein kinases.
Q35946386Tension-sensitive Plk1 phosphorylation on BubR1 regulates the stability of kinetochore microtubule interactions
Q34147935The CeCDC-14 phosphatase is required for cytokinesis in the Caenorhabditis elegans embryo
Q38896923The E3 ubiquitin ligase Mib1 regulates Plk4 and centriole biogenesis.
Q42487828The NIMA-related kinase X-Nek2B is required for efficient assembly of the zygotic centrosome in Xenopus laevis.
Q34454981The Plk1-dependent phosphoproteome of the early mitotic spindle
Q24292705The Polo kinase Plk4 functions in centriole duplication
Q52694987The SKP1-Cullin-F-box E3 ligase βTrCP and CDK2 cooperate to control STIL abundance and centriole number.
Q41391681The Ska complex promotes Aurora B activity to ensure chromosome biorientation.
Q28116287The Ste20-like kinase Mst2 activates the human large tumor suppressor kinase Lats1
Q36496562The autoregulated instability of Polo-like kinase 4 limits centrosome duplication to once per cell cycle
Q24336477The centrosomal protein nephrocystin-6 is mutated in Joubert syndrome and activates transcription factor ATF4
Q34221115The centrosome cycle: Centriole biogenesis, duplication and inherent asymmetries
Q38222110The centrosome duplication cycle in health and disease.
Q24644910The crystal structure of the human polo-like kinase-1 polo box domain and its phospho-peptide complex
Q28212662The dissociation of cohesin from chromosomes in prophase is regulated by Polo-like kinase
Q36219284The fates of chicken nuclear lamin proteins during mitosis: evidence for a reversible redistribution of lamin B2 between inner nuclear membrane and elements of the endoplasmic reticulum.
Q24556578The forkhead-associated domain protein Cep170 interacts with Polo-like kinase 1 and serves as a marker for mature centrioles
Q48078742The histone chaperone Asf1 is dispensable for direct de novo histone deposition in Xenopus egg extracts
Q54685334The role of the head and tail domain in lamin structure and assembly: analysis of bacterially expressed chicken lamin A and truncated B2 lamins
Q24313375The spindle protein CHICA mediates localization of the chromokinesin Kid to the mitotic spindle
Q37142551The substrates of the cdc2 kinase
Q33712012The transforming parasite Theileria co-opts host cell mitotic and central spindles to persist in continuously dividing cells
Q45795944The transforming protein of Moloney murine sarcoma virus is a soluble cytoplasmic protein.
Q24313155Timely anaphase onset requires a novel spindle and kinetochore complex comprising Ska1 and Ska2
Q36336805Tousled-like kinase functions with the chromatin assembly pathway regulating nuclear divisions
Q43218217Uncoupling of the spindle-checkpoint and chromosome-congression functions of BubR1.
Q34199659Uncovering the molecular machinery of the human spindle--an integration of wet and dry systems biology
Q30480149Use of the novel Plk1 inhibitor ZK-thiazolidinone to elucidate functions of Plk1 in early and late stages of mitosis
Q34613177Viral transactivators E1A and VP16 interact with a large complex that is associated with CTD kinase activity and contains CDK8
Q40445582Xenopus polo-like kinase Plx1 regulates XErp1, a novel inhibitor of APC/C activity

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