protein | Q8054 |
P705 | Ensembl protein ID | ENSMUSP00000005671 |
P637 | RefSeq protein ID | NP_034643 |
XP_006540704 | ||
XP_006540705 | ||
XP_006540706 | ||
XP_006540707 | ||
XP_006540708 | ||
XP_017177475 | ||
P352 | UniProt protein ID | Q60751 |
P682 | biological process | positive regulation of cold-induced thermogenesis | Q54810622 |
phosphorylation | Q242736 | ||
estrous cycle | Q388121 | ||
axonogenesis | Q14330656 | ||
brain development | Q14330969 | ||
positive regulation of phosphatidylinositol 3-kinase signaling | Q14330982 | ||
negative regulation of apoptotic process | Q14599533 | ||
positive regulation of cell population proliferation | Q14633891 | ||
insulin receptor signaling pathway | Q14758913 | ||
positive regulation of cell migration | Q14758919 | ||
glucose homeostasis | Q14758934 | ||
positive regulation of MAPK cascade | Q14758936 | ||
positive regulation of mitotic nuclear division | Q14758946 | ||
positive regulation of protein kinase B signaling | Q14761970 | ||
positive regulation of transcription, DNA-templated | Q14818066 | ||
protein tetramerization | Q14818074 | ||
male sex determination | Q14819278 | ||
adrenal gland development | Q14819869 | ||
response to ethanol | Q14819884 | ||
cerebellum development | Q14820054 | ||
cellular response to glucose stimulus | Q14859859 | ||
establishment of cell polarity | Q14859934 | ||
anatomical structure development | Q14860201 | ||
cellular response to insulin stimulus | Q14863071 | ||
epidermis development | Q14863096 | ||
negative regulation of DNA-binding transcription factor activity | Q14863100 | ||
exocrine pancreas development | Q14863352 | ||
transmembrane receptor protein tyrosine kinase signaling pathway | Q14863362 | ||
animal organ morphogenesis | Q14863363 | ||
immune response | Q1612119 | ||
protein autophosphorylation | Q3630494 | ||
mammary gland development | Q6745783 | ||
protein phosphorylation | Q7251493 | ||
insulin-like growth factor receptor signaling pathway | Q14863699 | ||
phosphatidylinositol-mediated signaling | Q14863700 | ||
positive regulation of smooth muscle cell proliferation | Q14863701 | ||
prostate gland epithelium morphogenesis | Q14863721 | ||
positive regulation of steroid hormone biosynthetic process | Q14863722 | ||
neuron projection development | Q14864368 | ||
negative regulation of protein kinase B signaling | Q14878366 | ||
cellular response to transforming growth factor beta stimulus | Q14881724 | ||
negative regulation of muscle cell apoptotic process | Q14882923 | ||
negative regulation of MAPK cascade | Q14883333 | ||
protein heterooligomerization | Q14884136 | ||
positive regulation of cytokinesis | Q14901454 | ||
regulation of JNK cascade | Q14901455 | ||
positive regulation of DNA metabolic process | Q14901459 | ||
positive regulation of osteoblast proliferation | Q14903134 | ||
positive regulation of axon regeneration | Q14906194 | ||
peptidyl-tyrosine autophosphorylation | Q15328828 | ||
dendritic spine maintenance | Q21095095 | ||
amyloid-beta clearance | Q21111526 | ||
cellular response to insulin-like growth factor stimulus | Q21118137 | ||
response to L-glutamate | Q21119123 | ||
positive regulation of protein-containing complex disassembly | Q21130717 | ||
positive regulation of meiotic cell cycle | Q21171628 | ||
cellular response to amyloid-beta | Q22273352 | ||
cellular response to angiotensin | Q22273368 | ||
negative regulation of hepatocyte apoptotic process | Q22304679 | ||
negative regulation of cholangiocyte apoptotic process | Q22304686 | ||
P681 | cell component | plasma membrane | Q29548 |
nucleus | Q40260 | ||
cytoplasm | Q79899 | ||
axon | Q178999 | ||
caveola | Q1051872 | ||
membrane | Q14349455 | ||
intracellular membrane-bounded organelle | Q14349519 | ||
neuron projection | Q14645640 | ||
neuronal cell body | Q14645696 | ||
integral component of plasma membrane | Q14859540 | ||
insulin receptor complex | Q14863336 | ||
T-tubule | Q2983734 | ||
integral component of membrane | Q14327652 | ||
receptor complex | Q14877465 | ||
alphav-beta3 integrin-IGF-1-IGF1R complex | Q21107751 | ||
P702 | encoded by | Igf1r | Q14901458 |
P703 | found in taxon | house mouse | Q83310 |
P527 | has part(s) | protein kinase, ATP binding site | Q24769051 |
Furin-like repeat | Q24774294 | ||
Receptor L-domain | Q24780479 | ||
Furin-like cysteine-rich domain | Q24787364 | ||
tyrosine-protein kinase, receptor class II, conserved site | Q24787466 | ||
tyrosine-protein kinase, catalytic domain | Q24719835 | ||
tyrosine-protein kinase, active site | Q24738472 | ||
fibronectin type III | Q24740327 | ||
serine-threonine/tyrosine-protein kinase, catalytic domain | Q24740842 | ||
protein kinase domain | Q24768234 | ||
P680 | molecular function | protein binding | Q167149 |
insulin receptor binding | Q14758896 | ||
identical protein binding | Q14762994 | ||
ATP binding | Q14817981 | ||
protein kinase activity | Q14820641 | ||
transferase activity | Q14840131 | ||
nucleotide binding | Q14860365 | ||
kinase activity | Q14863082 | ||
protein tyrosine kinase activity | Q14863338 | ||
insulin-activated receptor activity | Q14863340 | ||
insulin-like growth factor I binding | Q14863342 | ||
phosphatidylinositol 3-kinase binding | Q14863345 | ||
insulin binding | Q14863346 | ||
insulin receptor substrate binding | Q14863347 | ||
transmembrane receptor protein tyrosine kinase activity | Q14863358 | ||
G-protein alpha-subunit binding | Q14891374 | ||
insulin-like growth factor-activated receptor activity | Q14901451 | ||
insulin-like growth factor binding | Q14901452 | ||
P361 | part of | tyrosine-protein kinase, insulin-like receptor | Q24773020 |
Immunoglobulin-like fold | Q24787648 | ||
Fibronectin type III superfamily | Q41797245 | ||
Receptor L-domain superfamily | Q41798034 | ||
Tyrosine-protein kinase, catalytic domain, protein family | Q83130430 | ||
Serine-threonine/tyrosine-protein kinase, catalytic domain, protein family | Q83137014 | ||
Fibronectin type III, protein family | Q83137093 | ||
Protein kinase domain, protein family | Q83138186 | ||
membrane protein | Q423042 | ||
Receptor L-domain, protein family | Q83164437 | ||
Furin-like cysteine-rich domain, protein family | Q83166305 | ||
Tyrosine-protein kinase, receptor class II, conserved site, protein family | Q95350852 | ||
Furin-like repeat, protein family | Q95352652 | ||
Tyrosine-protein kinase, active site, protein family | Q95352684 | ||
Protein kinase, ATP binding site, protein family | Q95354221 | ||
Growth factor receptor cysteine-rich domain superfamily | Q24722567 | ||
Protein kinase-like domain superfamily | Q24726164 |
Q28592619 | Age-associated alterations in cardiac and skeletal muscle glucose transporters, insulin and IGF-1 receptors, and PI3-kinase protein contents in the C57BL/6 mouse |
Q28506578 | Conditional deletion of insulin-like growth factor-I receptor in prostate epithelium |
Q28587428 | Crosstalk between the p190-B RhoGAP and IGF signaling pathways is required for embryonic mammary bud development |
Q28590112 | Decreased insulin-like growth factor I-mediated protein tyrosine phosphorylation in human olivopontocerebellar atrophy and lurcher mutant mouse |
Q28512935 | Effects of mutations in the insulin-like growth factor signaling system on embryonic pancreas development and beta-cell compensation to insulin resistance |
Q39972622 | Essential Role of IGFIR in the Onset of Male Brown Fat Thermogenic Function: Regulation of Glucose Homeostasis by Differential Organ-Specific Insulin Sensitivity. |
Q24338901 | Focal adhesion kinase (FAK) activates and stabilizes IGF-1 receptor |
Q28589118 | Insulin and IGF1 receptors are essential for XX and XY gonadal differentiation and adrenal development in mice |
Q28156047 | Insulin receptor substrate-2 deficiency impairs brain growth and promotes tau phosphorylation |
Q28508182 | Insulin stimulates movement of sorting nexin 9 between cellular compartments: a putative role mediating cell surface receptor expression and insulin action |
Q28507173 | Insulin/IGF-1 controls epidermal morphogenesis via regulation of FoxO-mediated p63 inhibition |
Q28586271 | Lack of myotubularin (MTM1) leads to muscle hypotrophy through unbalanced regulation of the autophagy and ubiquitin-proteasome pathways |
Q28512518 | Testis determination requires insulin receptor family function in mice |
Q28505609 | The insulin-like growth factor pathway is altered in spinocerebellar ataxia type 1 and type 7 |
Q28508627 | The insulin-like growth factor-1 receptor is a negative regulator of nitric oxide bioavailability and insulin sensitivity in the endothelium |
Q28505191 | Two novel proteins that are linked to insulin-like growth factor (IGF-I) receptors by the Grb10 adapter and modulate IGF-I signaling |
Q28593654 | Zinc partitions insulin-like growth factors (IGFs) from soluble IGF binding protein (IGFBP)-5 to the cell surface receptors of BC3H-1 muscle cells |
Q14901458 | Igf1r | encodes | P688 |
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