Tyrosine kinase non receptor 2

mammalian protein found in Homo sapiens

Wikidata entity: Q21115284



P682 biological process ... Q189092 (cell migration) cell migration
P682 biological process ... Q189814 (endocytosis) endocytosis
P682 biological process ... Q210861 (cell differentiation) cell differentiation
P682 biological process ... Q242736 (phosphorylation) phosphorylation
P682 biological process ... Q428253 (innate immune response) innate immune response
P682 biological process ... Q828130 (signal transduction) signal transduction
P682 biological process ... Q7251493 (protein phosphorylation) protein phosphorylation
P682 biological process ... Q14331037 (positive regulation of peptidyl-tyrosine phosphorylation) positive regulation of peptidyl-tyrosine phosphorylation
P682 biological process ... Q14818120 (regulation of cell population proliferation) regulation of cell population proliferation
P682 biological process ... Q14820580 (cell surface receptor signaling pathway) cell surface receptor signaling pathway
P682 biological process ... Q14863362 (transmembrane receptor protein tyrosine kinase signaling pathway) transmembrane receptor protein tyrosine kinase signaling pathway
P682 biological process ... Q14865044 (small GTPase mediated signal transduction) small GTPase mediated signal transduction
P682 biological process ... Q15328828 (peptidyl-tyrosine autophosphorylation) peptidyl-tyrosine autophosphorylation
P682 biological process ... Q15331121 (negative regulation of GTPase activity) negative regulation of GTPase activity
P682 biological process ... Q21109452 (regulation of clathrin-dependent endocytosis) regulation of clathrin-dependent endocytosis
P681 cell component ... Q29548 (plasma membrane) plasma membrane
P681 cell component ... Q40260 (nucleus) nucleus
P681 cell component ... Q45173 (adherens junction) adherens junction
P681 cell component ... Q79899 (cytoplasm) cytoplasm
P681 cell component ... Q189073 (cell junction) cell junction
P681 cell component ... Q824237 (endosome) endosome
P681 cell component ... Q14330632 (perinuclear region of cytoplasm) perinuclear region of cytoplasm
P681 cell component ... Q14349455 (membrane) membrane
P681 cell component ... Q14840128 (cytoplasmic vesicle) cytoplasmic vesicle
P681 cell component ... Q14860540 (clathrin-coated pit) clathrin-coated pit
P681 cell component ... Q14862270 (cytoplasmic vesicle membrane) cytoplasmic vesicle membrane
P681 cell component ... Q14882520 (clathrin-coated vesicle) clathrin-coated vesicle
P681 cell component ... Q14905148 (extrinsic component of cytoplasmic side of plasma membrane) extrinsic component of cytoplasmic side of plasma membrane
P681 cell component ... Q14905185 (Grb2-EGFR complex) Grb2-EGFR complex
P681 cell component ... Q22329412 (cytoophidium) cytoophidium
P702 encoded by ... Q18035104 (TNK2) TNK2
P703 found in taxon ... Q15978631 (Homo sapiens) Homo sapiens
P527 has part(s) ... Q24719835 (tyrosine-protein kinase, catalytic domain) tyrosine-protein kinase, catalytic domain
P527 has part(s) ... Q24720233 (Cdc42 binding domain-like) Cdc42 binding domain-like
P527 has part(s) ... Q24738472 (tyrosine-protein kinase, active site) tyrosine-protein kinase, active site
P527 has part(s) ... Q24740842 (serine-threonine/tyrosine-protein kinase, catalytic domain) serine-threonine/tyrosine-protein kinase, catalytic domain
P527 has part(s) ... Q24768234 (protein kinase domain) protein kinase domain
P527 has part(s) ... Q24769051 (protein kinase, ATP binding site) protein kinase, ATP binding site
P527 has part(s) ... Q24770962 (Mig-6 domain) Mig-6 domain
P527 has part(s) ... Q24771787 (SH3 domain) SH3 domain
P31 instance of ... Q8054 (protein) protein
P680 molecular function ... Q167149 (protein binding) protein binding
P680 molecular function ... Q13667380 (metal ion binding) metal ion binding
P680 molecular function ... Q14326094 (protein serine/threonine kinase activity) protein serine/threonine kinase activity
P680 molecular function ... Q14331146 (protein serine/threonine/tyrosine kinase activity) protein serine/threonine/tyrosine kinase activity
P680 molecular function ... Q14633869 (ubiquitin protein ligase binding) ubiquitin protein ligase binding
P680 molecular function ... Q14762994 (identical protein binding) identical protein binding
P680 molecular function ... Q14817981 (ATP binding) ATP binding
P680 molecular function ... Q14820641 (protein kinase activity) protein kinase activity
P680 molecular function ... Q14840131 (transferase activity) transferase activity
P680 molecular function ... Q14860365 (nucleotide binding) nucleotide binding
P680 molecular function ... Q14863082 (kinase activity) kinase activity
P680 molecular function ... Q14863338 (protein tyrosine kinase activity) protein tyrosine kinase activity
P680 molecular function ... Q14864679 (epidermal growth factor receptor binding) epidermal growth factor receptor binding
P680 molecular function ... Q14873985 (non-membrane spanning protein tyrosine kinase activity) non-membrane spanning protein tyrosine kinase activity
P680 molecular function ... Q21096410 (GTPase inhibitor activity) GTPase inhibitor activity
P680 molecular function ... Q21831245 (WW domain binding) WW domain binding
P361 part of ... Q24726164 (Protein kinase-like domain superfamily) Protein kinase-like domain superfamily
P361 part of ... Q32854277 (Activated CDC42 kinase 1) Activated CDC42 kinase 1
P361 part of ... Q41797170 (SH3-like domain superfamily) SH3-like domain superfamily
P361 part of ... Q41798176 (Cdc42 binding domain-like superfamily) Cdc42 binding domain-like superfamily
P361 part of ... Q83130430 (Tyrosine-protein kinase, catalytic domain, protein family) Tyrosine-protein kinase, catalytic domain, protein family
P361 part of ... Q83130627 (Cdc42 binding domain-like, protein family) Cdc42 binding domain-like, protein family
P361 part of ... Q83137014 (Serine-threonine/tyrosine-protein kinase, catalytic domain, protein family) Serine-threonine/tyrosine-protein kinase, catalytic domain, protein family
P361 part of ... Q83138186 (Protein kinase domain, protein family) Protein kinase domain, protein family
P361 part of ... Q83140115 (Mig-6 domain, protein family) Mig-6 domain, protein family
P361 part of ... Q83140574 (SH3 domain, protein family) SH3 domain, protein family
P361 part of ... Q95352684 (Tyrosine-protein kinase, active site, protein family) Tyrosine-protein kinase, active site, protein family
P361 part of ... Q95354221 (Protein kinase, ATP binding site, protein family) Protein kinase, ATP binding site, protein family
P129 physically interacts with ... Q894611 (bosutinib) bosutinib

External Ids
P705Ensembl protein IDENSP00000392546
P705Ensembl protein IDENSP00000371341
P705Ensembl protein IDENSP00000329425
P705Ensembl protein IDENSP00000395588
P638PDB structure ID4ID7
P638PDB structure ID1U4D
P638PDB structure ID3EQR
P638PDB structure ID4EWH
P638PDB structure ID3EQP
P638PDB structure ID1CF4
P638PDB structure ID1U46
P638PDB structure ID1U54
P638PDB structure ID4HZR
P638PDB structure ID4HZS
P637RefSeq protein IDNP_001010938
P637RefSeq protein IDNP_001294975
P637RefSeq protein IDNP_005772
P637RefSeq protein IDXP_005269325
P637RefSeq protein IDXP_005269327
P637RefSeq protein IDXP_005269331
P637RefSeq protein IDXP_005269332
P637RefSeq protein IDXP_011510619
P637RefSeq protein IDXP_011510620
P637RefSeq protein IDXP_011510622
P637RefSeq protein IDXP_011510623
P637RefSeq protein IDXP_016860997
P637RefSeq protein IDXP_016860998
P637RefSeq protein IDXP_016860999
P637RefSeq protein IDXP_024309059
P637RefSeq protein IDXP_024309060
P637RefSeq protein IDXP_024309061
P637RefSeq protein IDXP_024309062
P637RefSeq protein IDXP_024309063
P352UniProt protein IDQ07912

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