bosutinib

chemical compound

Wikidata entity: Q894611

C₂₆H₂₉Cl₂N₅O₃ (P274)


Wikimedia Commons category is Bosutinib



Quantities

P2067mass529.165

P3780 active ingredient in ... Q29004916 (Bosulif) Bosulif
P233 canonical SMILES String CN1CCN(CC1)CCCOC2=C(C=C3C(=C2)N=CC(=C3NC4=CC(=C(C=C4Cl)Cl)OC)C#N)OC ???
P373 Commons category String Bosutinib ???
P366 has use ... Q12140 (medication) medication
P31 instance of ... Q113145171 (type of chemical entity) type of chemical entity
P8026 LiverTox likelihood score ... Q83284515 (LiverTox toxicity likelihood category D) LiverTox toxicity likelihood category D
P2175 medical condition treated ... Q29496 (leukemia) leukemia
P1748 NCI Thesaurus ID String C60809 ???
P129 physically interacts with ... Q423628 (FYN proto-oncogene, Src family tyrosine kinase) FYN proto-oncogene, Src family tyrosine kinase
P129 physically interacts with ... Q587961 (ABL proto-oncogene 1, non-receptor tyrosine kinase) ABL proto-oncogene 1, non-receptor tyrosine kinase
P129 physically interacts with ... Q2463389 (LYN proto-oncogene, Src family tyrosine kinase) LYN proto-oncogene, Src family tyrosine kinase
P129 physically interacts with ... Q21106691 (Fyn related Src family tyrosine kinase) Fyn related Src family tyrosine kinase
P129 physically interacts with ... Q21109354 (SRC proto-oncogene, non-receptor tyrosine kinase) SRC proto-oncogene, non-receptor tyrosine kinase
P129 physically interacts with ... Q21113540 (Calcium/calmodulin dependent protein kinase ID) Calcium/calmodulin dependent protein kinase ID
P129 physically interacts with ... Q21115284 (Tyrosine kinase non receptor 2) Tyrosine kinase non receptor 2
P129 physically interacts with ... Q21116513 (Serine/threonine kinase 4) Serine/threonine kinase 4
P129 physically interacts with ... Q21117407 (Serine/threonine kinase 24) Serine/threonine kinase 24
P129 physically interacts with ... Q21118356 (Calcium/calmodulin dependent protein kinase II gamma) Calcium/calmodulin dependent protein kinase II gamma
P129 physically interacts with ... Q21119231 (TXK tyrosine kinase) TXK tyrosine kinase
P129 physically interacts with ... Q21127300 (Serine/threonine kinase 10) Serine/threonine kinase 10
P129 physically interacts with ... Q21130085 (Mitogen-activated protein kinase kinase kinase kinase 5) Mitogen-activated protein kinase kinase kinase kinase 5
P3489 pregnancy category ... Q28123618 (US pregnancy category D) US pregnancy category D
P769 significant drug interaction ... Q118551 (clarithromycin) clarithromycin
P769 significant drug interaction ... Q213511 (erythromycin) erythromycin
P769 significant drug interaction ... Q412236 (voriconazole) voriconazole
P769 significant drug interaction ... Q5186964 (crizotinib) crizotinib
P769 significant drug interaction ... Q5908266 (idelalisib) idelalisib
P279 subclass of ... Q11173 (chemical compound) chemical compound
P2868 subject has role ... Q50348938 (xenobiotic-transporting ATPase inhibitor) xenobiotic-transporting ATPase inhibitor
P2868 subject has role ... Q7251487 (protein kinase inhibitors) protein kinase inhibitors

External Ids
P267ATC codeL01XE14
P231CAS Registry Number380843-75-4
P683ChEBI ID39112
P592ChEMBL IDCHEMBL288441
P661ChemSpider ID4486102
P715DrugBank IDDB06616
P11198DrugCentral ID4359
P3117DSSTox substance IDDTXSID10861568
P232EC number700-455-1
P2566ECHA Substance Infocard ID100.149.122
P646Freebase ID/m/043pypy
P595Guide to Pharmacology Ligand ID5710
P2057Human Metabolome Database IDHMDB0240205
P234InChIInChI=1S/C26H29Cl2N5O3/c1-32-6-8-33(9-7-32)5-4-10-36-25-13-21-18(11-24(25)35-3)26(17(15-29)16-30-21)31-22-14-23(34-2)20(28)12-19(22)27/h11-14,16H,4-10H2,1-3H3,(H,30,31)
P235InChIKeyUBPYILGKFZZVDX-UHFFFAOYSA-N
P665KEGG IDD03252
P7830LiverTox IDBosutinib
P10245MedlinePlus drug identifiera613005
P486MeSH descriptor IDC471992
P6366Microsoft Academic ID (discontinued)2778208673
P2115NDF-RT IDN0000185728
P10283OpenAlex IDC2778208673
P3636PDB ligand IDDB8
P638PDB structure ID3SOA
P638PDB structure ID5AJQ
P638PDB structure ID3UE4
P638PDB structure ID4MXY
P638PDB structure ID4MXZ
P638PDB structure ID4MXX
P638PDB structure ID4MXO
P638PDB structure ID4OTW
P638PDB structure ID4QMN
P11199Probes And Drugs IDPD004099
P662PubChem CID5328940
P1579Reaxys registry number9100307
P3345RxNorm CUI1307619
P4964SPLASHsplash10-001l-1900080000-86f44693fc4098040447
P2877SureChEMBL ID158390
P4527UK Parliament thesaurus ID433698
P2892UMLS CUIC1174836
P2892UMLS CUIC1831731
P11089UniChem compound ID11972
P652UNII5018V4AEZ0
P11143WikiProjectMed IDBosutinib

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