FYN proto-oncogene, Src family tyrosine kinase

mammalian protein found in Homo sapiens

Wikidata entity: Q423628



P682 biological process ... Q133500 (learning) learning
P682 biological process ... Q189092 (cell migration) cell migration
P682 biological process ... Q210861 (cell differentiation) cell differentiation
P682 biological process ... Q242736 (phosphorylation) phosphorylation
P682 biological process ... Q179217 (blood coagulation) blood coagulation
P682 biological process ... Q2034716 (axon guidance) axon guidance
P682 biological process ... Q3630494 (protein autophosphorylation) protein autophosphorylation
P682 biological process ... Q7251493 (protein phosphorylation) protein phosphorylation
P682 biological process ... Q14330812 (forebrain development) forebrain development
P682 biological process ... Q14330959 (neuron migration) neuron migration
P682 biological process ... Q14330967 (central nervous system development) central nervous system development
P682 biological process ... Q14330979 (positive regulation of neuron projection development) positive regulation of neuron projection development
P682 biological process ... Q14330982 (positive regulation of phosphatidylinositol 3-kinase signaling) positive regulation of phosphatidylinositol 3-kinase signaling
P682 biological process ... Q14330986 (peptidyl-tyrosine phosphorylation) peptidyl-tyrosine phosphorylation
P682 biological process ... Q428253 (innate immune response) innate immune response
P682 biological process ... Q14818120 (regulation of cell population proliferation) regulation of cell population proliferation
P682 biological process ... Q14819291 (response to hydrogen peroxide) response to hydrogen peroxide
P682 biological process ... Q14819462 (regulation of cell shape) regulation of cell shape
P682 biological process ... Q14819467 (platelet activation) platelet activation
P682 biological process ... Q14819471 (leukocyte migration) leukocyte migration
P682 biological process ... Q14819639 (cellular response to growth factor stimulus) cellular response to growth factor stimulus
P682 biological process ... Q14819856 (feeding behavior) feeding behavior
P682 biological process ... Q14819859 (negative regulation of gene expression) negative regulation of gene expression
P682 biological process ... Q14331055 (modulation of chemical synaptic transmission) modulation of chemical synaptic transmission
P682 biological process ... Q14599681 (calcium ion transport) calcium ion transport
P682 biological process ... Q14633911 (regulation of apoptotic process) regulation of apoptotic process
P682 biological process ... Q14645705 (multicellular organism development) multicellular organism development
P682 biological process ... Q14758900 (MAPK cascade) MAPK cascade
P682 biological process ... Q14758933 (negative regulation of protein catabolic process) negative regulation of protein catabolic process
P682 biological process ... Q14761970 (positive regulation of protein kinase B signaling) positive regulation of protein kinase B signaling
P682 biological process ... Q14864605 (dendrite morphogenesis) dendrite morphogenesis
P682 biological process ... Q14864697 (regulation of peptidyl-tyrosine phosphorylation) regulation of peptidyl-tyrosine phosphorylation
P682 biological process ... Q14865169 (viral process) viral process
P682 biological process ... Q14865394 (T cell costimulation) T cell costimulation
P682 biological process ... Q14865402 (mitigation of host defenses by virus) mitigation of host defenses by virus
P682 biological process ... Q14877687 (negative regulation of extrinsic apoptotic signaling pathway in absence of ligand) negative regulation of extrinsic apoptotic signaling pathway in absence of ligand
P682 biological process ... Q14878792 (positive regulation of protein localization to nucleus) positive regulation of protein localization to nucleus
P682 biological process ... Q14881724 (cellular response to transforming growth factor beta stimulus) cellular response to transforming growth factor beta stimulus
P682 biological process ... Q14881863 (positive regulation of cysteine-type endopeptidase activity) positive regulation of cysteine-type endopeptidase activity
P682 biological process ... Q14885636 (vascular endothelial growth factor receptor signaling pathway) vascular endothelial growth factor receptor signaling pathway
P682 biological process ... Q14887688 (phosphatidylinositol phosphate biosynthetic process) phosphatidylinositol phosphate biosynthetic process
P682 biological process ... Q14887714 (adaptive immune response) adaptive immune response
P682 biological process ... Q14897688 (detection of mechanical stimulus involved in sensory perception of pain) detection of mechanical stimulus involved in sensory perception of pain
P682 biological process ... Q14904367 (negative regulation of protein ubiquitination) negative regulation of protein ubiquitination
P682 biological process ... Q14904989 (activated T cell proliferation) activated T cell proliferation
P682 biological process ... Q14905487 (ephrin receptor signaling pathway) ephrin receptor signaling pathway
P682 biological process ... Q14905665 (cellular response to peptide hormone stimulus) cellular response to peptide hormone stimulus
P682 biological process ... Q14906083 (positive regulation of GTPase activity) positive regulation of GTPase activity
P682 biological process ... Q14907233 (positive regulation of tyrosine phosphorylation of STAT protein) positive regulation of tyrosine phosphorylation of STAT protein
P682 biological process ... Q27862133 (regulation of calcium ion import across plasma membrane) regulation of calcium ion import across plasma membrane
P682 biological process ... Q14907708 (positive regulation of neuron death) positive regulation of neuron death
P682 biological process ... Q14916317 (immune system process) immune system process
P682 biological process ... Q15328828 (peptidyl-tyrosine autophosphorylation) peptidyl-tyrosine autophosphorylation
P682 biological process ... Q21095095 (dendritic spine maintenance) dendritic spine maintenance
P682 biological process ... Q21095173 (stimulatory C-type lectin receptor signaling pathway) stimulatory C-type lectin receptor signaling pathway
P682 biological process ... Q21096414 (cellular response to platelet-derived growth factor stimulus) cellular response to platelet-derived growth factor stimulus
P682 biological process ... Q21097326 (negative regulation of oxidative stress-induced cell death) negative regulation of oxidative stress-induced cell death
P682 biological process ... Q21097363 (positive regulation of non-membrane spanning protein tyrosine kinase activity) positive regulation of non-membrane spanning protein tyrosine kinase activity
P682 biological process ... Q21100433 (positive regulation of protein targeting to membrane) positive regulation of protein targeting to membrane
P682 biological process ... Q21100616 (regulation of phosphatidylinositol 3-kinase signaling) regulation of phosphatidylinositol 3-kinase signaling
P682 biological process ... Q21133478 (negative regulation of hydrogen peroxide biosynthetic process) negative regulation of hydrogen peroxide biosynthetic process
P682 biological process ... Q21170202 (negative regulation of dendritic spine maintenance) negative regulation of dendritic spine maintenance
P682 biological process ... Q22272332 (response to singlet oxygen) response to singlet oxygen
P682 biological process ... Q22273351 (response to amyloid-beta) response to amyloid-beta
P682 biological process ... Q22273352 (cellular response to amyloid-beta) cellular response to amyloid-beta
P682 biological process ... Q22299874 (regulation of glutamate receptor signaling pathway) regulation of glutamate receptor signaling pathway
P682 biological process ... Q22306711 (heart process) heart process
P682 biological process ... Q24575309 (cellular response to L-glutamate) cellular response to L-glutamate
P682 biological process ... Q27116608 (cellular response to glycine) cellular response to glycine
P682 biological process ... Q27118160 (positive regulation of protein localization to membrane) positive regulation of protein localization to membrane
P682 biological process ... Q14819884 (response to ethanol) response to ethanol
P682 biological process ... Q14820580 (cell surface receptor signaling pathway) cell surface receptor signaling pathway
P682 biological process ... Q14820618 (negative regulation of neuron apoptotic process) negative regulation of neuron apoptotic process
P682 biological process ... Q14851952 (intracellular signal transduction) intracellular signal transduction
P682 biological process ... Q14863107 (cytokine-mediated signaling pathway) cytokine-mediated signaling pathway
P682 biological process ... Q14863362 (transmembrane receptor protein tyrosine kinase signaling pathway) transmembrane receptor protein tyrosine kinase signaling pathway
P682 biological process ... Q14863700 (phosphatidylinositol-mediated signaling) phosphatidylinositol-mediated signaling
P682 biological process ... Q14863968 (Fc-gamma receptor signaling pathway involved in phagocytosis) Fc-gamma receptor signaling pathway involved in phagocytosis
P682 biological process ... Q14863969 (T cell activation) T cell activation
P682 biological process ... Q14863970 (T cell receptor signaling pathway) T cell receptor signaling pathway
P682 biological process ... Q14864035 (positive regulation of I-kappaB kinase/NF-kappaB signaling) positive regulation of I-kappaB kinase/NF-kappaB signaling
P681 cell component ... Q79899 (cytoplasm) cytoplasm
P681 cell component ... Q220599 (cytosol) cytosol
P681 cell component ... Q329638 (actin filament) actin filament
P681 cell component ... Q424178 (membrane raft) membrane raft
P681 cell component ... Q4374336 (postsynaptic density) postsynaptic density
P681 cell component ... Q12821248 (dendrite) dendrite
P681 cell component ... Q14330632 (perinuclear region of cytoplasm) perinuclear region of cytoplasm
P681 cell component ... Q824237 (endosome) endosome
P681 cell component ... Q14349455 (membrane) membrane
P681 cell component ... Q14349519 (intracellular membrane-bounded organelle) intracellular membrane-bounded organelle
P681 cell component ... Q14864171 (cell periphery) cell periphery
P681 cell component ... Q14864866 (cell body) cell body
P681 cell component ... Q14905148 (extrinsic component of cytoplasmic side of plasma membrane) extrinsic component of cytoplasmic side of plasma membrane
P681 cell component ... Q27918503 (postsynaptic density, intracellular component) postsynaptic density, intracellular component
P681 cell component ... Q29574383 (Schaffer collateral - CA1 synapse) Schaffer collateral - CA1 synapse
P681 cell component ... Q21103123 (perinuclear endoplasmic reticulum) perinuclear endoplasmic reticulum
P681 cell component ... Q21108295 (glial cell projection) glial cell projection
P681 cell component ... Q24629101 (glutamatergic synapse) glutamatergic synapse
P681 cell component ... Q29548 (plasma membrane) plasma membrane
P681 cell component ... Q39572 (mitochondrion) mitochondrion
P681 cell component ... Q40260 (nucleus) nucleus
P702 encoded by ... Q18024903 (FYN) FYN
P2888 exact match Url UniProt ???
P703 found in taxon ... Q15978631 (Homo sapiens) Homo sapiens
P692 Gene Atlas image CommonsMedia http://commons.wikimedia.org/wiki/Special:FilePath/PBB%20GE%20FYN%20210105%20s%20at%20fs.png ???
P527 has part(s) ... Q41796901 (Fyn/Yrk, SH3 domain) Fyn/Yrk, SH3 domain
P527 has part(s) ... Q24719835 (tyrosine-protein kinase, catalytic domain) tyrosine-protein kinase, catalytic domain
P527 has part(s) ... Q24738472 (tyrosine-protein kinase, active site) tyrosine-protein kinase, active site
P527 has part(s) ... Q24740842 (serine-threonine/tyrosine-protein kinase, catalytic domain) serine-threonine/tyrosine-protein kinase, catalytic domain
P527 has part(s) ... Q24768234 (protein kinase domain) protein kinase domain
P527 has part(s) ... Q24769051 (protein kinase, ATP binding site) protein kinase, ATP binding site
P527 has part(s) ... Q24771787 (SH3 domain) SH3 domain
P527 has part(s) ... Q24780316 (SH2 domain) SH2 domain
P31 instance of ... Q8054 (protein) protein
P680 molecular function ... Q167149 (protein binding) protein binding
P680 molecular function ... Q13667380 (metal ion binding) metal ion binding
P680 molecular function ... Q14762994 (identical protein binding) identical protein binding
P680 molecular function ... Q14817981 (ATP binding) ATP binding
P680 molecular function ... Q14819233 (signaling receptor binding) signaling receptor binding
P680 molecular function ... Q14819775 (G protein-coupled receptor binding) G protein-coupled receptor binding
P680 molecular function ... Q14599289 (enzyme binding) enzyme binding
P680 molecular function ... Q14762993 (tubulin binding) tubulin binding
P680 molecular function ... Q14865844 (growth factor receptor binding) growth factor receptor binding
P680 molecular function ... Q14873985 (non-membrane spanning protein tyrosine kinase activity) non-membrane spanning protein tyrosine kinase activity
P680 molecular function ... Q14885196 (CD4 receptor binding) CD4 receptor binding
P680 molecular function ... Q14885197 (CD8 receptor binding) CD8 receptor binding
P680 molecular function ... Q14887675 (phosphatidylinositol-4,5-bisphosphate 3-kinase activity) phosphatidylinositol-4,5-bisphosphate 3-kinase activity
P680 molecular function ... Q14897681 (ephrin receptor binding) ephrin receptor binding
P680 molecular function ... Q14901685 (transmembrane transporter binding) transmembrane transporter binding
P680 molecular function ... Q14905529 (T cell receptor binding) T cell receptor binding
P680 molecular function ... Q27123456 (disordered domain specific binding) disordered domain specific binding
P680 molecular function ... Q15324791 (tau-protein kinase activity) tau-protein kinase activity
P680 molecular function ... Q22312641 (type 5 metabotropic glutamate receptor binding) type 5 metabotropic glutamate receptor binding
P680 molecular function ... Q22312857 (protein-containing complex binding) protein-containing complex binding
P680 molecular function ... Q14820602 (peptide hormone receptor binding) peptide hormone receptor binding
P680 molecular function ... Q14820641 (protein kinase activity) protein kinase activity
P680 molecular function ... Q14820643 (signal transducer activity) signal transducer activity
P680 molecular function ... Q14840131 (transferase activity) transferase activity
P680 molecular function ... Q14860365 (nucleotide binding) nucleotide binding
P680 molecular function ... Q14860857 (alpha-tubulin binding) alpha-tubulin binding
P680 molecular function ... Q14860860 (tau protein binding) tau protein binding
P680 molecular function ... Q14863082 (kinase activity) kinase activity
P680 molecular function ... Q14863338 (protein tyrosine kinase activity) protein tyrosine kinase activity
P680 molecular function ... Q14863345 (phosphatidylinositol 3-kinase binding) phosphatidylinositol 3-kinase binding
P361 part of ... Q41797170 (SH3-like domain superfamily) SH3-like domain superfamily
P361 part of ... Q41797956 (SH2 domain superfamily) SH2 domain superfamily
P361 part of ... Q50261758 (Src family kinases (SFKs) [cytosol]) Src family kinases (SFKs) [cytosol]
P361 part of ... Q83130430 (Tyrosine-protein kinase, catalytic domain, protein family) Tyrosine-protein kinase, catalytic domain, protein family
P361 part of ... Q83137014 (Serine-threonine/tyrosine-protein kinase, catalytic domain, protein family) Serine-threonine/tyrosine-protein kinase, catalytic domain, protein family
P361 part of ... Q83138186 (Protein kinase domain, protein family) Protein kinase domain, protein family
P361 part of ... Q83140574 (SH3 domain, protein family) SH3 domain, protein family
P361 part of ... Q83164644 (SH2 domain, protein family) SH2 domain, protein family
P361 part of ... Q83172438 (Fyn/Yrk, SH3 domain, protein family) Fyn/Yrk, SH3 domain, protein family
P361 part of ... Q95352684 (Tyrosine-protein kinase, active site, protein family) Tyrosine-protein kinase, active site, protein family
P361 part of ... Q95354221 (Protein kinase, ATP binding site, protein family) Protein kinase, ATP binding site, protein family
P361 part of ... Q24726164 (Protein kinase-like domain superfamily) Protein kinase-like domain superfamily
P129 physically interacts with ... Q894611 (bosutinib) bosutinib

External Ids
P705Ensembl protein IDENSP00000430455
P705Ensembl protein IDENSP00000346671
P705Ensembl protein IDENSP00000229471
P705Ensembl protein IDENSP00000428983
P705Ensembl protein IDENSP00000429813
P705Ensembl protein IDENSP00000428045
P705Ensembl protein IDENSP00000429992
P705Ensembl protein IDENSP00000429294
P705Ensembl protein IDENSP00000430364
P705Ensembl protein IDENSP00000357671
P705Ensembl protein IDENSP00000428493
P705Ensembl protein IDENSP00000357656
P705Ensembl protein IDENSP00000357667
P705Ensembl protein IDENSP00000427993
P705Ensembl protein IDENSP00000428042
P705Ensembl protein IDENSP00000429866
P705Ensembl protein IDENSP00000440646
P705Ensembl protein IDENSP00000429590
P705Ensembl protein IDENSP00000428695
P646Freebase ID/m/03cc30q
P486MeSH descriptor IDD051076
P672MeSH tree codeD08.811.913.696.620.682.725.800.551
P672MeSH tree codeD12.776.476.568.800.551
P672MeSH tree codeD12.776.624.664.700.180
P6366Microsoft Academic ID (discontinued)2910472280
P6366Microsoft Academic ID (discontinued)37686147
P10283OpenAlex IDC37686147
P638PDB structure ID4U1P
P638PDB structure ID2DQ7
P638PDB structure ID3H0F
P638PDB structure ID1NYG
P638PDB structure ID1EFN
P638PDB structure ID4D8D
P638PDB structure ID1M27
P638PDB structure ID1G83
P638PDB structure ID1A0N
P638PDB structure ID1AOT
P638PDB structure ID1AOU
P638PDB structure ID1AVZ
P638PDB structure ID1AZG
P638PDB structure ID1FYN
P638PDB structure ID1NYF
P638PDB structure ID1SHF
P638PDB structure ID1ZBJ
P638PDB structure ID2MQI
P638PDB structure ID2MRJ
P638PDB structure ID2MRK
P638PDB structure ID3H0H
P638PDB structure ID3H0I
P638PDB structure ID3UA6
P638PDB structure ID3UA7
P638PDB structure ID4EIK
P638PDB structure ID4U17
P638PDB structure ID4ZNX
P637RefSeq protein IDNP_001357458
P637RefSeq protein IDNP_002028
P637RefSeq protein IDNP_694592
P637RefSeq protein IDNP_694593
P637RefSeq protein IDXP_005266949
P637RefSeq protein IDXP_016866139
P637RefSeq protein IDXP_016866140
P637RefSeq protein IDXP_016866141
P637RefSeq protein IDXP_016866142
P637RefSeq protein IDXP_016866144
P352UniProt protein IDP06241

Why not click here or view trends?

log id: 5825349