Inhibiting heat shock factor 1 in human cancer cells with a potent RNA aptamer

scientific article published in 2014

Inhibiting heat shock factor 1 in human cancer cells with a potent RNA aptamer is …
instance of (P31):
scholarly articleQ13442814

External links are
P819ADS bibcode2014PLoSO...996330S
P356DOI10.1371/JOURNAL.PONE.0096330
P932PMC publication ID4011729
P698PubMed publication ID24800749
P5875ResearchGate publication ID262109397

P2093author name stringRichard A Cerione
John T Lis
Marc A Antonyak
Hua Shi
H Hans Salamanca
P2860cites workRegulation of longevity in Caenorhabditis elegans by heat shock factor and molecular chaperonesQ35799651
Transcription Factor and Polymerase Recruitment, Modification, and Movement on dhsp70 In Vivo in the Minutes following Heat ShockQ36139169
Tanespimycin with bortezomib: activity in relapsed/refractory patients with multiple myelomaQ36162690
Targeting Hsp90 for the treatment of cancer.Q36556620
An RNA aptamer that interferes with the DNA binding of the HSF transcription activator.Q38310815
H1 RNA polymerase III promoter-driven expression of an RNA aptamer leads to high-level inhibition of intracellular protein activity.Q38311335
Selection and characterization of an RNA decoy for transcription factor NF-kappa B.Q38327211
Characterization of a new human diploid cell strain, IMR-90.Q42802708
Geldanamycin and 17-allylamino-17-demethoxygeldanamycin potentiate the in vitro and in vivo radiation response of cervical tumor cells via the heat shock protein 90-mediated intracellular signaling and cytotoxicity.Q44705946
Plants contain a novel multi-member class of heat shock factors without transcriptional activator potentialQ47819460
Heat Shock Factor 2 (HSF2) Contributes to Inducible Expression ofhspGenes through Interplay with HSF1Q59572058
Isolation of a cDNA for HSF2: evidence for two heat shock factor genes in humansQ24324038
The genomic and transcriptomic landscape of a HeLa cell lineQ24632989
Heat shock factor 1 is a powerful multifaceted modifier of carcinogenesisQ24655006
Distinct transcriptional responses of RNA polymerases I, II and III to aptamers that bind TBPQ24807338
Crystal structure of NF- B (p50)2 complexed to a high-affinity RNA aptamerQ27641747
Isolation of the gene encoding the S. cerevisiae heat shock transcription factorQ27939979
An RNA aptamer perturbs heat shock transcription factor activity in Drosophila melanogasterQ28237753
Cloning and characterization of two mouse heat shock factors with distinct inducible and constitutive DNA-binding abilityQ28279289
Apoptosis: a review of programmed cell deathQ28305845
HSF1 is required for extra-embryonic development, postnatal growth and protection during inflammatory responses in miceQ28588529
Activation of heat shock gene transcription by heat shock factor 1 involves oligomerization, acquisition of DNA-binding activity, and nuclear localization and can occur in the absence of stressQ28609211
Regulation of the heat shock transcriptional response: cross talk between a family of heat shock factors, molecular chaperones, and negative regulatorsQ29618401
Phase I study of BIIB028, a selective heat shock protein 90 inhibitor, in patients with refractory metastatic or locally advanced solid tumorsQ33163062
Selection and characterization of anti-NF-kappaB p65 RNA aptamersQ33329753
Inhibition of Hsp90 down-regulates mutant epidermal growth factor receptor (EGFR) expression and sensitizes EGFR mutant tumors to paclitaxelQ33571026
Probing TBP interactions in transcription initiation and reinitiation with RNA aptamers that act in distinct modes.Q33781651
Multiple functions of Drosophila heat shock transcription factor in vivoQ33886554
Conservation of a stress response: human heat shock transcription factors functionally substitute for yeast HSF.Q33887676
Knocking down gene function with an RNA aptamer expressed as part of an intronQ34080091
Mouse heat shock transcription factor 1 deficiency alters cardiac redox homeostasis and increases mitochondrial oxidative damageQ34149797
HSF1 drives a transcriptional program distinct from heat shock to support highly malignant human cancersQ34292197
Heat shock transcription factors: structure and regulationQ34387283
Multicenter phase II trial of the heat shock protein 90 inhibitor, retaspimycin hydrochloride (IPI-504), in patients with castration-resistant prostate cancerQ35194754
RNA aptamers as effective protein antagonists in a multicellular organismQ35613156
A phase II study of gemcitabine in combination with tanespimycin in advanced epithelial ovarian and primary peritoneal carcinomaQ35691439
P275copyright licenseCreative Commons Attribution 4.0 InternationalQ20007257
P6216copyright statuscopyrightedQ50423863
P433issue5
P407language of work or nameEnglishQ1860
P304page(s)e96330
P577publication date2014-01-01
P1433published inPLOS OneQ564954
P1476titleInhibiting heat shock factor 1 in human cancer cells with a potent RNA aptamer
P478volume9

Reverse relations

cites work (P2860)
Q35224117An RNA aptamer specific to Hsp70-ATP conformation inhibits its ATPase activity independent of Hsp40.
Q89454336Aptamers: Uptake mechanisms and intracellular applications
Q89876909Chemical Biology Framework to Illuminate Proteostasis
Q58594721HSF1 as a Cancer Biomarker and Therapeutic Target
Q36490084HSF1: Guardian of Proteostasis in Cancer
Q101044484Implication of heat shock proteins in rotavirus entry into Reh cells
Q45873648Incorporation of aptamers in the terminal loop of shRNAs yields an effective and novel combinatorial targeting strategy
Q57179194Influence of hyperthermal regimes on experimental teratoma development in vitro
Q36201349Inverse relationship between Alzheimer's disease and cancer, and other factors contributing to Alzheimer's disease: a systematic review
Q42237173New inhibitor targeting human transcription factor HSF1: effects on the heat shock response and tumor cell survival
Q37702284Proof-of Concept that an Acute Trophic Factors Intervention After Spinal Cord Injury Provides an Adequate Niche for Neuroprotection, Recruitment of Nestin-Expressing Progenitors and Regeneration
Q46832829Protection of Momordica charantia polysaccharide against intracerebral hemorrhage-induced brain injury through JNK3 signaling pathway
Q38287714RNA aptamers targeted for human αA-crystallin do not bind αB-crystallin, and spare the α-crystallin domain
Q38667614Specific labeling: An effective tool to explore the RNA world
Q41660505Targeting Heat Shock Proteins in Cancer: A Promising Therapeutic Approach
Q50557388The heat-shock, or HSF1-mediated proteotoxic stress, response in cancer: from proteomic stability to oncogenesis
Q38503345When Cancer Fights Back: Multiple Myeloma, Proteasome Inhibition, and the Heat-Shock Response

Search more.