Embryonic stem cell-derived microvesicles reprogram hematopoietic progenitors: evidence for horizontal transfer of mRNA and protein delivery

scientific article published on 2 February 2006

Embryonic stem cell-derived microvesicles reprogram hematopoietic progenitors: evidence for horizontal transfer of mRNA and protein delivery is …
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scholarly articleQ13442814

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P6179Dimensions Publication ID1046811448
P356DOI10.1038/SJ.LEU.2404132
P3181OpenCitations bibliographic resource ID699275
P698PubMed publication ID16453000
P5875ResearchGate publication ID7321220

P50authorMariusz RatajczakQ11770192
Petr DvorakQ39062371
Magdalena KuciaQ61942769
P2093author name stringJ Zhang
J Ratajczak
R Reca
K Miekus
P2860cites workNuclear reprogramming of somatic cells after fusion with human embryonic stem cellsQ28269087
A role for Wnt signalling in self-renewal of haematopoietic stem cellsQ28592213
Maintenance of pluripotency in human and mouse embryonic stem cells through activation of Wnt signaling by a pharmacological GSK-3-specific inhibitorQ29614622
Wnt proteins are lipid-modified and can act as stem cell growth factorsQ29615009
Segregation of RNA and separate packaging of DNA and RNA in apoptotic bodies during apoptosisQ33181284
Reprogrammed gene expression in a somatic cell-free extractQ33757733
The induction of matrix metalloproteinase and cytokine expression in synovial fibroblasts stimulated with immune cell microparticlesQ33831170
Argosomes: a potential vehicle for the spread of morphogens through epitheliaQ34090785
Microparticles in cardiovascular diseases.Q34221054
Nanotubular highways for intercellular organelle transportQ34298770
Global gene expression analysis of the living human fetus using cell-free messenger RNA in amniotic fluidQ34394846
RNA as a long-distance information macromolecule in plantsQ34443618
Circulating nucleic acids and proteomics of plasma/serum: clinical utilityQ35835700
Cellular microparticles: a disseminated storage pool of bioactive vascular effectorsQ35838107
Mechanisms of soluble cytokine receptor generationQ35923165
The role of intranuclear lipids.Q35935663
Horizontal transfer of oncogenes by uptake of apoptotic bodiesQ35946111
The Trojan exosome hypothesisQ35976953
The role of membranes and membrane trafficking in RNA localizationQ35985156
Cells release prions in association with exosomesQ36448448
Nuclei of embryonic stem cells reprogram somatic cellsQ38334452
Platelet- and megakaryocyte-derived microparticles transfer CXCR4 receptor to CXCR4-null cells and make them susceptible to infection by X4-HIV.Q39412581
Microvesicles derived from activated platelets induce metastasis and angiogenesis in lung cancerQ40500955
Vesicle traffic through intercellular bridges in DU 145 human prostate cancer cells.Q40502913
Proinvasive properties of ovarian cancer ascites-derived membrane vesiclesQ40507973
Platelet-derived microparticles stimulate proliferation, survival, adhesion, and chemotaxis of hematopoietic cellsQ40729733
Reprogramming fibroblasts to express T-cell functions using cell extractsQ40735257
Endocytic entry of HIV-1.Q40855363
A trans-receptor mechanism for infection of CD4-negative cells by human immunodeficiency virus type 1.Q40952571
Mobilization studies in mice deficient in either C3 or C3a receptor (C3aR) reveal a novel role for complement in retention of hematopoietic stem/progenitor cells in bone marrowQ44646941
Incorporation of CXCR4 into membrane lipid rafts primes homing-related responses of hematopoietic stem/progenitor cells to an SDF-1 gradientQ45029569
Hematopoietic stem cells convert into liver cells within days without fusionQ47631908
Nuclear reprogramming—alchemy or analysis?Q57086633
Biochemical and NMR studies on structure and release conditions of RNA-containing vesicles shed by human colon adenocarcinoma cellsQ61095293
Numerous growth factors, cytokines, and chemokines are secreted by human CD34+ cells, myeloblasts, erythroblasts, and megakaryoblasts and regulate normal hematopoiesis in an autocrine/paracrine mannerQ61942737
Platelet-derived microparticles bind to hematopoietic stem/progenitor cells and enhance their engraftmentQ61942738
Activated Platelets Release Two Types of Membrane Vesicles: Microvesicles by Surface Shedding and Exosomes Derived From Exocytosis of Multivesicular Bodies and -GranulesQ107392236
P433issue5
P407language of work or nameEnglishQ1860
P304page(s)847-856
P577publication date2006-02-02
P1433published inLeukemiaQ6534498
P1476titleEmbryonic stem cell-derived microvesicles reprogram hematopoietic progenitors: evidence for horizontal transfer of mRNA and protein delivery
P478volume20

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Q35154283Inferring alterations in cell-to-cell communication in HER2+ breast cancer using secretome profiling of three cell models
Q35089453Inflammation-induced endothelial cell-derived extracellular vesicles modulate the cellular status of pericytes
Q38215360Information handling by the brain: proposal of a new "paradigm" involving the roamer type of volume transmission and the tunneling nanotube type of wiring transmission
Q89947669Inhalation of lung spheroid cell secretome and exosomes promotes lung repair in pulmonary fibrosis
Q39740145Inhibition of LINE-1 and Alu retrotransposition by exosomes encapsidating APOBEC3G and APOBEC3F.
Q89719755Intravenous Administration of Allogenic Cell-Derived Microvesicles of Healthy Origins Defend Against Atherosclerotic Cardiovascular Disease Development by a Direct Action on Endothelial Progenitor Cells
Q38800211Introduction to Extracellular Vesicles: Biogenesis, RNA Cargo Selection, Content, Release, and Uptake
Q38872063In Vivo imaging reveals extracellular vesicle-mediated phenocopying of metastatic behavior
Q58226894Isolation and Characterization of Extracellular Vesicles in Stem Cell-Related Studies
Q40413509Isolation of Exosomes and Microvesicles from Cell Culture Systems to Study Prion Transmission
Q28087005Isolation of extracellular vesicles: Determining the correct approach (Review)
Q58702047Isolation, Culture, and Functional Characterization of Human Embryonic Stem Cells: Current Trends and Challenges
Q37125856Itinerant exosomes: emerging roles in cell and tissue polarity
Q37810517Janus head: the dual role of HLA-G in CNS immunity
Q40196309KRAS and BRAF mutations in serum exosomes from patients with colorectal cancer in a Chinese population
Q35756936L Particles Transmit Viral Proteins from Herpes Simplex Virus 1-Infected Mature Dendritic Cells to Uninfected Bystander Cells, Inducing CD83 Downmodulation
Q58708585Lab-on-Chip for Exosomes and Microvesicles Detection and Characterization
Q42796042Large-scale generation of cell-derived nanovesicles
Q57282157Large-scale preparation of extracellular vesicles enriched with specific microRNA
Q38269348Leukemia cell microvesicles promote survival in umbilical cord blood hematopoietic stem cells.
Q38952093Leukemia microvesicles affect healthy hematopoietic stem cells.
Q90853964Liquid biopsies to guide therapeutic decisions in rheumatoid arthritis
Q55187959Liquid biopsy in pancreatic cancer: the beginning of a new era.
Q41895573Liver extracellular vesicles in health and disease
Q41206883Long Distance Metabolic Regulation through Adipose-Derived Circulating Exosomal miRNAs: A Trail for RNA-Based Therapies?
Q37180308Lung cancer screening: from imaging to biomarker
Q37403299Lung cancer secreted microvesicles: underappreciated modulators of microenvironment in expanding tumors
Q37526963Macroautophagy and Selective Mitophagy Ameliorate Chondrogenic Differentiation Potential in Adipose Stem Cells of Equine Metabolic Syndrome: New Findings in the Field of Progenitor Cells Differentiation
Q37434730Macrophage Foam Cell-Derived Extracellular Vesicles Promote Vascular Smooth Muscle Cell Migration and Adhesion
Q33918018Macrophage immunomodulation by breast cancer-derived exosomes requires Toll-like receptor 2-mediated activation of NF-κB.
Q36595322Macrophage microvesicles induce macrophage differentiation and miR-223 transfer
Q92781911Malignant Glioma Therapy by Vaccination with Irradiated C6 Cell-Derived Microvesicles Promotes an Antitumoral Immune Response
Q34645721Mammalian Argonaute-DNA binding?
Q35005372Mapping the small RNA content of simian immunodeficiency virions (SIV)
Q36057277Marrow cell genetic phenotype change induced by human lung cancer cells
Q29618139Melanoma exosomes educate bone marrow progenitor cells toward a pro-metastatic phenotype through MET
Q29547765Membrane vesicles as conveyors of immune responses
Q29615670Membrane-derived microvesicles: important and underappreciated mediators of cell-to-cell communication
Q57170602Mesenchymal Stem Cell Derived Exosomes in Cancer Progression, Metastasis and Drug Delivery: A Comprehensive Review
Q91714327Mesenchymal Stem Cell Derived Extracellular Vesicles Ameliorate Kidney Injury in Aristolochic Acid Nephropathy
Q33755190Mesenchymal Stem Cell Derived Extracellular Vesicles: A Role in Hematopoietic Transplantation?
Q90617296Mesenchymal Stem Cell-Derived Extracellular Vesicles in Tissue Regeneration
Q36706478Mesenchymal Stem Cell-Derived Microvesicles Support Ex Vivo Expansion of Cord Blood-Derived CD34(+) Cells
Q39238366Mesenchymal Stem Cell-derived Extracellular Vesicles for Renal Repair
Q39419410Mesenchymal Stem/Stromal Cell-Derived Extracellular Vesicles and Their Potential as Novel Immunomodulatory Therapeutic Agents
Q91899785Mesenchymal Stromal Cell-Based Bone Regeneration Therapies: From Cell Transplantation and Tissue Engineering to Therapeutic Secretomes and Extracellular Vesicles
Q60938459Mesenchymal Stromal Cell-Derived Exosomes Affect mRNA Expression and Function of B-Lymphocytes
Q41918085Mesenchymal Stromal Cell-Derived Extracellular Vesicles Provide Long-term Survival after Total Body Irradiation without additional Hematopoietic Stem Cell Support.
Q36074972Mesenchymal Stromal Cells Epithelial Transition Induced by Renal Tubular Cells-Derived Extracellular Vesicles
Q37614303Mesenchymal stem cell derived secretome and extracellular vesicles for acute lung injury and other inflammatory lung diseases.
Q64097130Mesenchymal stem cell exosomes: a two-edged sword in cancer therapy
Q41831728Mesenchymal stem cell secreted vesicles provide novel opportunities in (stem) cell-free therapy
Q38543282Mesenchymal stem cell treatment for hemophilia: a review of current knowledge.
Q92841047Mesenchymal stem cell-derived extracellular vesicles promote nerve regeneration after sciatic nerve crush injury in rats
Q52663977Mesenchymal stem cell-derived extracellular vesicles: novel frontiers in regenerative medicine.
Q34158605Mesenchymal stem cell-derived microparticles: a promising therapeutic strategy
Q37176871Mesenchymal stem cell-derived microvesicles protect against acute tubular injury
Q37899553Mesenchymal stem cells and acute lung injury
Q37310677Mesenchymal stem cells expressing TRAIL lead to tumour growth inhibition in an experimental lung cancer model
Q90412540Mesenchymal stem cells from different sources and their derived exosomes: A pre-clinical perspective
Q38734475Mesenchymal stromal cell-derived extracellular vesicles rescue radiation damage to murine marrow hematopoietic cells.
Q57267891Methods for Biomarker Analysis
Q42069315MiRNAs and piRNAs from bone marrow mesenchymal stem cell extracellular vesicles induce cell survival and inhibit cell differentiation of cord blood hematopoietic stem cells: a new insight in transplantation
Q35060575MicroRNA in exosomes isolated directly from the liver circulation in patients with metastatic uveal melanoma.
Q29614237MicroRNA signatures of tumor-derived exosomes as diagnostic biomarkers of ovarian cancer
Q47107821MicroRNA-containing extracellular vesicles released from endothelial colony-forming cells modulate angiogenesis during ischaemic retinopathy.
Q27027663MicroRNAs are shaping the hematopoietic landscape
Q27013998MicroRNAs as biomarkers for CNS disease
Q37872226MicroRNAs as biomarkers of disease onset.
Q38165818MicroRNAs delivered by extracellular vesicles: an emerging resistance mechanism for breast cancer.
Q38887851MicroRNAs in extracellular vesicles: potential cancer biomarkers
Q39856376MicroRNAs in human embryonic and cancer stem cells
Q88122126MicroRNAs of Equine Amniotic Mesenchymal Cell-derived Microvesicles and Their Involvement in Anti-inflammatory Processes
Q26741214MicroRNAs: Potential Biomarkers and Therapeutic Targets for Alveolar Bone Loss in Periodontal Disease
Q64110563Microglia-Derived Microvesicles Affect Microglia Phenotype in Glioma
Q34533653Microparticle-mediated transfer of the viral receptors CAR and CD46, and the CFTR channel in a CHO cell model confers new functions to target cells
Q35087871Microparticles from kidney-derived mesenchymal stem cells act as carriers of proangiogenic signals and contribute to recovery from acute kidney injury.
Q38012180Microparticles, not only markers but also a therapeutic target in the early stage of diabetic retinopathy and vascular aging
Q37769584Microparticles--messengers of biological information
Q35792749Microparticles: major transport vehicles for distinct microRNAs in circulation
Q41232230Microvesicle Induction of Prostate Specific Gene Expression in Normal Human Bone Marrow Cells
Q47127903Microvesicle Involvement in Shiga Toxin-Associated Infection
Q21147072Microvesicle entry into marrow cells mediates tissue-specific changes in mRNA by direct delivery of mRNA and induction of transcription
Q43556329Microvesicle-mediated Wnt/β-Catenin Signaling Promotes Interspecies Mammary Stem/Progenitor Cell Growth
Q64100377Microvesicles and chemokines in tumor microenvironment: mediators of intercellular communications in tumor progression
Q38137085Microvesicles and intercellular communication in the context of parasitism.
Q28079166Microvesicles as Vehicles for Tissue Regeneration: Changing of the Guards
Q38452579Microvesicles as immune orchestra conductors
Q37841221Microvesicles as mediators of intercellular communication in cancer--the emerging science of cellular 'debris'.
Q37686479Microvesicles as mediators of tissue regeneration
Q37955969Microvesicles as novel biomarkers and therapeutic targets in transplantation medicine.
Q28750201Microvesicles derived from adult human bone marrow and tissue specific mesenchymal stem cells shuttle selected pattern of miRNAs
Q58831473Microvesicles derived from endothelial progenitor cells protect the kidney from ischemia–reperfusion injury by microRNA-dependent reprogramming of resident renal cells
Q33568086Microvesicles derived from human Wharton's jelly mesenchymal stem cells promote human renal cancer cell growth and aggressiveness through induction of hepatocyte growth factor
Q34674941Microvesicles derived from human umbilical cord Wharton's jelly mesenchymal stem cells attenuate bladder tumor cell growth in vitro and in vivo
Q34354584Microvesicles derived from human umbilical cord mesenchymal stem cells stimulated by hypoxia promote angiogenesis both in vitro and in vivo
Q28731306Microvesicles derived from mesenchymal stem cells enhance survival in a lethal model of acute kidney injury
Q37981578Microvesicles in health and disease.
Q37017724Microvesicles provide a mechanism for intercellular communication by embryonic stem cells during embryo implantation
Q35077269Microvesicles secreted from human multiple myeloma cells promote angiogenesis
Q24628728Microvesicles: mediators of extracellular communication during cancer progression
Q37273154Microvesicles: potential markers and mediators of endothelial dysfunction
Q42226744Milk's Role as an Epigenetic Regulator in Health and Disease
Q36232987Minireview: Emerging Roles for Extracellular Vesicles in Diabetes and Related Metabolic Disorders
Q91650600Modeling Cell Communication in Cancer With Organoids: Making the Complex Simple
Q52605943Modularized Extracellular Vesicles: The Dawn of Prospective Personalized and Precision Medicine.
Q83202684Modulation of cellular behavior by exogenous messenger RNA
Q42256345Molecular characterization of human osteoblast-derived extracellular vesicle mRNA using next-generation sequencing.
Q36847231Molecular pathways: tumor-derived microvesicles and their interactions with immune cells in vivo
Q26777469Molecular signatures of mesenchymal stem cell-derived extracellular vesicle-mediated tissue repair
Q36550793More Than Tiny Sacks: Stem Cell Exosomes as Cell-Free Modality for Cardiac Repair
Q38134570Moving RNA moves RNA forward
Q37507833Nanofilaments on glioblastoma exosomes revealed by peak force microscopy.
Q33522242Nanostructural and transcriptomic analyses of human saliva derived exosomes
Q24642271Nanotubes, exosomes, and nucleic acid-binding peptides provide novel mechanisms of intercellular communication in eukaryotic cells: implications in health and disease
Q58785905New Insights Into Immune Cell-Derived Extracellular Vesicles in Multiple Sclerosis
Q64782418New windows into the brain: Central nervous system-derived extracellular vesicles in blood
Q42361723Nexus between extracellular vesicles, immunomodulation and tissue remodeling: for good or for bad?
Q35630132Non-cell-autonomous RNA interference in mammalian cells: Implications for in vivo cell-based RNAi delivery.
Q47148827Non-coding RNAs in Mesenchymal Stem Cell-Derived Extracellular Vesicles: Deciphering Regulatory Roles in Stem Cell Potency, Inflammatory Resolve, and Tissue Regeneration.
Q55052671Noncoding RNAs Carried by Extracellular Vesicles in Endocrine Diseases.
Q37321828Noncoding RNAs in Long-Term Memory Formation
Q30360749Obstacles and opportunities in the functional analysis of extracellular vesicle RNA - an ISEV position paper
Q36330702Of Cytometry, Stem Cells and Fountain of Youth
Q61799559On the Choice of the Extracellular Vesicles for Therapeutic Purposes
Q42361704On the function and heterogeneity of extracellular vesicles
Q36193774Oncogenic extracellular vesicles in brain tumor progression
Q64095329Optimisation of laboratory methods for whole transcriptomic RNA analyses in human left ventricular biopsies and blood samples of clinical relevance
Q27015774Optimization of pre-transplantation conditions to enhance the efficacy of mesenchymal stem cells
Q37227933Osteoblasts secrete miRNA-containing extracellular vesicles that enhance expansion of human umbilical cord blood cells
Q38835020PML-RARa modulates the vascular signature of extracellular vesicles released by acute promyelocytic leukemia cells.
Q37382231Pancreatic cancer diagnosis by free and exosomal miRNA.
Q26741215Pancreatic cancer stem cell markers and exosomes - the incentive push
Q26739740Paracrine Signaling by Extracellular Vesicles via Osteoblasts
Q38204262Paracrine effects of stem cells in wound healing and cancer progression (Review).
Q42854848Paracrine proangiopoietic effects of human umbilical cord blood-derived purified CD133+ cells--implications for stem cell therapies in regenerative medicine
Q35233608Parasite extracellular vesicles: mediators of intercellular communication
Q37672913Pathogens hijack the epigenome: a new twist on host-pathogen interactions.
Q52722785Peripheral Blood Cell Interactions of Cancer-Derived Exosomes Affect Immune Function.
Q35632958Perspectives on the Potential Therapeutic Uses of Vesicles.
Q38170072Physiological and pathological relevance of secretory microRNAs and a perspective on their clinical application
Q37969874Pivotal role of paracrine effects in stem cell therapies in regenerative medicine: can we translate stem cell-secreted paracrine factors and microvesicles into better therapeutic strategies?
Q38244018Placenta-derived exosomes and syncytiotrophoblast microparticles and their role in human reproduction: immune modulation for pregnancy success
Q64296078Plant Extracellular Vesicles Contain Diverse Small RNA Species and Are Enriched in 10- to 17-Nucleotide "Tiny" RNAs
Q38392023Plasma-derived Extracellular Vesicles Contain Predictive Biomarkers and Potential Therapeutic Targets for Myocardial Ischemic (MI) Injury.
Q38044999Platelet microRNAs: From platelet biology to possible disease biomarkers and therapeutic targets.
Q36058568Platelets and platelet-like particles mediate intercellular RNA transfer
Q37265491Port-to-port delivery: Mobilization of toxic sphingolipids via extracellular vesicles
Q26796775Potential Reparative Role of Resident Adult Renal Stem/Progenitor Cells in Acute Kidney Injury
Q26861645Potential Therapies by Stem Cell-Derived Exosomes in CNS Diseases: Focusing on the Neurogenic Niche
Q48344924Potential roles of metalloproteinases of endometrium-derived exosomes in embryo-maternal crosstalk during implantation.
Q44378272Pre-metastatic cancer exosomes induce immune surveillance by patrolling monocytes at the metastatic niche.
Q38743711Pre-metastatic niches: organ-specific homes for metastases.
Q39404696Pregnancy and spontaneous fetal loss: A pig perspective.
Q37996455Premetastatic niche: ready for new therapeutic interventions?
Q89823874Preservation techniques of stem cells extracellular vesicles: a gate for manufacturing of clinical grade therapeutic extracellular vesicles and long-term clinical trials
Q35792720Profiling of circulating microRNAs: from single biomarkers to re-wired networks
Q41852564Progenitor/stem cell fate determination: interactive dynamics of cell cycle and microvesicles
Q48268616Protein Characterization of Extracellular Microvesicles/Exosomes Released from Cytotoxin-Challenged Rat Cerebrocortical Mixed Culture and Mouse N2a Cells
Q38585869Protein transfer into human cells by VSV-G-induced nanovesicles.
Q38092801Proteolytic factors in exosomes
Q38494818Proteomic profiling of secreted proteins for the hematopoietic support of interleukin-stimulated human umbilical vein endothelial cells.
Q38629150Proteomics of cell-cell interactions in health and disease.
Q38080806Proteomics, transcriptomics and lipidomics of exosomes and ectosomes.
Q40220857Pseudotyping exosomes for enhanced protein delivery in mammalian cells
Q35668891Quantitative and qualitative analysis of small RNAs in human endothelial cells and exosomes provides insights into localized RNA processing, degradation and sorting
Q38926438Quantitative changes in the protein and miRNA cargo of plasma exosome-like vesicles after exposure to ionizing radiation.
Q39107313RNA in extracellular vesicles
Q39076891Re-Engineering Extracellular Vesicles as Smart Nanoscale Therapeutics.
Q92644016Reduction of the therapeutic dose of silencing RNA by packaging it in extracellular vesicles via a pre-microRNA backbone
Q39017698Regulation of exosome release by glycosphingolipids and flotillins
Q38717262Regulation of prostate cancer progression by the tumor microenvironment
Q26795744Regulation of the Host Antiviral State by Intercellular Communications
Q38659518Renal Tubular Cell-Derived Extracellular Vesicles Accelerate the Recovery of Established Renal Ischemia Reperfusion Injury
Q38814818Renal extracellular vesicles: from physiology to clinical application
Q41048103Reproducible and scalable purification of extracellular vesicles using combined bind-elute and size exclusion chromatography.
Q28469365Reprogramming Malignant Cancer Cells toward a Benign Phenotype following Exposure to Human Embryonic Stem Cell Microenvironment
Q50055320Retinal progenitor cells release extracellular vesicles containing developmental transcription factors, microRNA and membrane proteins.
Q37669563Ribonucleic artefacts: are some extracellular RNA discoveries driven by cell culture medium components?
Q36684242Role of Alix in miRNA packaging during extracellular vesicle biogenesis
Q27000282Role of Exosomal Noncoding RNAs in Lung Carcinogenesis
Q89820638Role of Extracellular Vesicles in Cellular Cross Talk in Malaria
Q90384169Role of Mesenchymal Stem Cell-Derived Extracellular Vesicles in Epithelial-Mesenchymal Transition
Q21129255Role of exosomes/microvesicles in the nervous system and use in emerging therapies
Q26786205Role of extracellular RNA-carrying vesicles in cell differentiation and reprogramming
Q99579318Role of mesenchymal stem cell derived extracellular vesicles in autoimmunity: A systematic review
Q38079531Role of mesenchymal stem cell-derived microvesicles in tissue repair.
Q33684644Role of stem cell-derived exosomes in cancer
Q38688358Roles of exosomes in the normal and diseased eye.
Q35857342Roll over Weismann: extracellular vesicles in the transgenerational transmission of environmental effects
Q33798474Saline is a more appropriate solution for microvesicles for flow cytometric analyses
Q34669417Saliva: diagnostics and therapeutic perspectives
Q93080687Salivary Extracellular Vesicle-Associated exRNA as Cancer Biomarker
Q38781006Schwann Cell Exosomes Mediate Neuron-Glia Communication and Enhance Axonal Regeneration
Q64074734Secretome of adipose-derived mesenchymal stem cells promotes skeletal muscle regeneration through synergistic action of extracellular vesicle cargo and soluble proteins
Q33728084Selective release of microRNA species from normal and malignant mammary epithelial cells
Q39172386Selective secretion of microRNA in CNS system
Q51098153Self-Renewal of Bone Marrow Stem Cells by Nanovesicles Engineered from Embryonic Stem Cells.
Q37372370Senescence, apoptosis, and stem cell biology: the rationale for an expanded view of intracrine action
Q38815925Sensing protein antigen and microvesicle analytes using high-capacity biopolymer nano-carriers
Q58719702Sensitive and rapid quantification of exosomes by fusing luciferase to exosome marker proteins
Q26752817Sensitivity of Dendritic Cells to Microenvironment Signals
Q90266605Serum-free media supplements carry miRNAs that co-purify with extracellular vesicles
Q24607278Small RNA deep sequencing reveals a distinct miRNA signature released in exosomes from prion-infected neuronal cells
Q55039327Small RNA profiling of low biomass samples: identification and removal of contaminants.
Q38202537Small but mighty: microparticles as mediators of tumor progression
Q57811526Small non-coding RNA landscape of extracellular vesicles from human stem cells
Q41228077Social networking in tumor cell communities is associated with increased aggressiveness
Q33822089Sources and Functions of Extracellular Small RNAs in Human Circulation
Q90854406Specificities of secretion and uptake of exosomes and other extracellular vesicles for cell-to-cell communication
Q50079745Sphingolipid pathway enzymes modulate cell fate and immune responses
Q41851773Stability of membranous nanostructures: a possible key mechanism in cancer progression
Q37141132Stable cell fate changes in marrow cells induced by lung-derived microvesicles
Q38798555Stem Cell Extracellular Vesicles: Extended Messages of Regeneration
Q39124190Stem Cell Technology in Cardiac Regeneration: A Pluripotent Stem Cell Promise
Q55071721Stem Cell-Derived Exosome in Cardiovascular Diseases: Macro Roles of Micro Particles.
Q26767434Stem Cell-Derived Exosomes: A Potential Alternative Therapeutic Agent in Orthopaedics
Q28069239Stem Cell-Derived Extracellular Vesicles and Immune-Modulation
Q90721850Stem Cell-Derived Extracellular Vesicles and Kidney Regeneration
Q47099701Stem cell extracellular vesicles and kidney injury.
Q33921305Stem cell plasticity revisited: the continuum marrow model and phenotypic changes mediated by microvesicles
Q38586627Stem cell-derived exosomes: roles in stromal remodeling, tumor progression, and cancer immunotherapy
Q30486086Stem cells and cell therapies in lung biology and lung diseases
Q84303950Stem cells and cell therapies in lung biology and lung diseases
Q34361245Stem cells and cell therapy approaches in lung biology and diseases
Q98291548Stem cells and stem cell-derived extracellular vesicles in acute and chronic kidney diseases: mechanisms of repair
Q26862657Stem cells as drug delivery methods: application of stem cell secretome for regeneration
Q86892039Studying extracellular vesicle transfer by a Cre-loxP method
Q38136096Synthetic nucleic acids delivered by exosomes: a potential therapeutic for generelated metabolic brain diseases
Q27004655Systemic mirnas as potential biomarkers for malignancy
Q34519276TNF-α alters the release and transfer of microparticle-encapsulated miRNAs from endothelial cells
Q38888391TRAIL delivery by MSC-derived extracellular vesicles is an effective anticancer therapy
Q89965559Targeting Extracellular Vesicles to the Arthritic Joint Using a Damaged Cartilage-Specific Antibody
Q42558443Targeting Wnt pathway in mantle cell lymphoma-initiating cells.
Q26741206Telocytes and Their Extracellular Vesicles-Evidence and Hypotheses
Q59806470The Crosstalk between Cancer Stem Cells and Microenvironment Is Critical for Solid Tumor Progression: The Significant Contribution of Extracellular Vesicles
Q49332525The Effect of Mesenchymal Stem Cell-Derived Extracellular Vesicles on Hematopoietic Stem Cells Fate.
Q41995331The Multifaceted Functions of Exosomes in Health and Disease: An Overview.
Q61796708The Regenerative Potential of Amniotic Fluid Stem Cell Extracellular Vesicles: Lessons Learned by Comparing Different Isolation Techniques
Q35684577The Role of Cancer Stem Cells in the Organ Tropism of Breast Cancer Metastasis: A Mechanistic Balance between the "Seed" and the "Soil"?
Q99591126The Role of Exosomes in Stemness and Neurodegenerative Diseases-Chemoresistant-Cancer Therapeutics and Phytochemicals
Q92394700The Role of Extracellular Vesicles as Paracrine Effectors in Stem Cell-Based Therapies
Q38638043The Role of Extracellular Vesicles: An Epigenetic View of the Cancer Microenvironment
Q41068275The Role of Microvesicles Derived from Mesenchymal Stem Cells in Lung Diseases
Q90363306The Roles of miRNA in Glioblastoma Tumor Cell Communication: Diplomatic and Aggressive Negotiations
Q38365386The Secret Role of microRNAs in Cancer Stem Cell Development and Potential Therapy: A Notch-Pathway Approach
Q36737945The biology and function of exosomes in cancer
Q38115783The complexity, function and applications of RNA in circulation
Q26775288The current landscape of the mesenchymal stromal cell secretome: A new paradigm for cell-free regeneration
Q35971555The genomic and proteomic content of cancer cell-derived exosomes
Q37974382The multifaceted exosome: biogenesis, role in normal and aberrant cellular function, and frontiers for pharmacological and biomarker opportunities
Q38164634The origin, function, and diagnostic potential of extracellular microRNAs in human body fluids
Q35830790The paradoxical dynamism of marrow stem cells: considerations of stem cells, niches, and microvesicles
Q33563134The regulation of inflammatory mediators in acute kidney injury via exogenous mesenchymal stem cells.
Q39741387The release of microparticles by Jurkat leukemia T cells treated with staurosporine and related kinase inhibitors to induce apoptosis
Q35095098The ribonome: a dominant force in co-ordinating gene expression
Q28069899The role of exosomes contents on genetic and epigenetic alterations of recipient cancer cells
Q59131778The role of extracellular vesicles in biomineralisation: current perspective and application in regenerative medicine
Q26800735The role of microenvironment and immunity in drug response in leukemia
Q90430751The role of microvesicles containing microRNAs in vascular endothelial dysfunction
Q37875634The role of microvesicles in tissue repair.
Q38171466The roles of extracellular vesicles in cancer biology: toward the development of novel cancer biomarkers
Q35606520The roles of tumor-derived exosomes in cancer pathogenesis
Q41631738The transition of smooth muscle cells from a contractile to a migratory, phagocytic phenotype: direct demonstration of phenotypic modulation
Q90397450Therapeutic Advances of Stem Cell-Derived Extracellular Vesicles in Regenerative Medicine
Q36096318Therapeutic Effects of Human Mesenchymal Stem Cell-derived Microvesicles in Severe Pneumonia in Mice.
Q101451663Therapeutic potential of mesenchymal stem cell-derived extracellular vesicles as novel cell-free therapy for treatment of autoimmune disorders
Q38031213Therapeutic potential of mesenchymal stem cell-derived microvesicles.
Q37421157Therapeutic potential of plasma membrane-derived microparticles
Q58570616Therapeutic potential of products derived from mesenchymal stem/stromal cells in pulmonary disease
Q92733083Thrombin Preconditioning Boosts Biogenesis of Extracellular Vesicles from Mesenchymal Stem Cells and Enriches Their Cargo Contents via Protease-Activated Receptor-Mediated Signaling Pathways
Q38256369Tolerance in organ transplantation: from conventional immunosuppression to extracellular vesicles.
Q36988371Toward a theory of the primo vascular system: a hypothetical circulatory system at the subcellular level
Q58118698Towards mechanisms and standardization in extracellular vesicle and extracellular RNA studies: results of a worldwide survey
Q38616669Towards the realization of clinical extracellular vesicle diagnostics: challenges and opportunities
Q52894719Transcriptional profiling of the hematopoietic support of interleukin-stimulated human umbilical vein endothelial cells (HUVECs).
Q34850542Transcriptome of extracellular vesicles released by hepatocytes.
Q42196845Transfer of growth factor receptor mRNA via exosomes unravels the regenerative effect of mesenchymal stem cells
Q21143855Transfer of microRNAs by embryonic stem cell microvesicles
Q38019496Transfer of vesicles from schwann cells to axons: a novel mechanism of communication in the peripheral nervous system
Q36888987Transport of sequence-specific RNA interference information between cells.
Q64114307Tumor-derived exosomal HMGB1 promotes esophageal squamous cell carcinoma progression through inducing PD1 TAM expansion
Q38243188Tumor-derived exosomes in oncogenic reprogramming and cancer progression
Q54986381Tumor-derived exosomes induce PD1+ macrophage population in human gastric cancer that promotes disease progression.
Q27023509Tumor-derived microvesicles: shedding light on novel microenvironment modulators and prospective cancer biomarkers
Q89892838Two-step magnetic bead-based (2MBB) techniques for immunocapture of extracellular vesicles and quantification of microRNAs for cardiovascular diseases: A pilot study
Q36438947Ultrastructural evidence of exosome secretion by progenitor cells in adult mouse myocardium and adult human cardiospheres
Q56346556Unbiased classification of mosquito blood cells by single-cell genomics and high-content imaging
Q24300024Unidirectional transfer of microRNA-loaded exosomes from T cells to antigen-presenting cells
Q92276370Uptake of lymphoma-derived exosomes by peripheral blood leukocytes
Q91822259Urinary Extracellular Vesicles Carrying Klotho Improve the Recovery of Renal Function in an Acute Tubular Injury Model
Q37872261Urinary exosomes and proteomics
Q53074101Vascular endothelial growth factor mediates the therapeutic efficacy of mesenchymal stem cell-derived extracellular vesicles against neonatal hyperoxic lung injury.
Q35215645Very small embryonic-like (VSEL) stem cells in adult organs and their potential role in rejuvenation of tissues and longevity
Q37155637Very small embryonic-like (VSEL) stem cells: purification from adult organs, characterization, and biological significance
Q38883154Vesicle-MaNiA: extracellular vesicles in liquid biopsy and cancer
Q53489250Vesiculated Long Non-Coding RNAs: Offshore Packages Deciphering Trans-Regulation between Cells, Cancer Progression and Resistance to Therapies.
Q89724511Where does the cargo go?: Solutions to provide experimental support for the "extracellular vesicle cargo transfer hypothesis"
Q50578329Why the need and how to approach the functional diversity of extracellular vesicles.
Q28077330Wnt Signaling in Cell Motility and Invasion: Drawing Parallels between Development and Cancer
Q94589438[Progress in extracellular vesicle imaging methods]
Q35989190mRNA fragments in in vitro culture media are associated with bovine preimplantation embryonic development
Q36053822miR-1289 and "Zipcode"-like Sequence Enrich mRNAs in Microvesicles
Q28071987miR-200c Regulation of Metastases in Ovarian Cancer: Potential Role in Epithelial and Mesenchymal Transition
Q93083318miRNAs in stem cell-derived extracellular vesicles for acute kidney injury treatment: comprehensive review of preclinical studies

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