Mesenchymal stem cells expressing TRAIL lead to tumour growth inhibition in an experimental lung cancer model

scientific article published on 28 March 2008

Mesenchymal stem cells expressing TRAIL lead to tumour growth inhibition in an experimental lung cancer model is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.1111/J.1582-4934.2008.00317.X
P932PMC publication ID3828879
P698PubMed publication ID18373740
P5875ResearchGate publication ID5478381

P50authorRalf Michael ZwackaQ57250345
P2093author name stringLinda Howard
Frank Barry
Tim O'Brien
Georgina Shaw
Mark Lyons
Andrea Mohr
Laura Deedigan
Ralf Zwacka
Tina Harte
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Endothelial progenitor cell derived microvesicles activate an angiogenic program in endothelial cells by a horizontal transfer of mRNA.Q34632614
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Alteration of marrow cell gene expression, protein production, and engraftment into lung by lung-derived microvesicles: a novel mechanism for phenotype modulation.Q36035053
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Mesenchymal stem cells in cancer: tumor-associated fibroblasts and cell-based delivery vehiclesQ36901346
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Prophylaxis against carcinogenesis in three kinds of unestablished tumor models via IL12-gene-engineered MSCsQ40253468
Adenovirus type 5 interactions with human blood cells may compromise systemic delivery.Q40297306
Vascular endothelial growth factor A contributes to glioma-induced migration of human marrow stromal cells (hMSC).Q40298054
Mesenchymal progenitor cells as cellular vehicles for delivery of oncolytic adenovirusesQ40302572
AAV-encoded expression of TRAIL in experimental human colorectal cancer leads to tumor regression.Q40582634
Cell to cell contact required for bystander effect of the TNF-related apoptosis-inducing ligand (TRAIL) geneQ40648897
Mechanisms involved in development of resistance to adenovirus-mediated proapoptotic gene therapy in DLD1 human colon cancer cell line.Q40705843
Adenoviral-mediated transfer of the TNF-related apoptosis-inducing ligand/Apo-2 ligand gene induces tumor cell apoptosisQ40860890
Polymer-coated adenovirus permits efficient retargeting and evades neutralising antibodies.Q43583253
Resistance of prostate cancer cells to soluble TNF-related apoptosis-inducing ligand (TRAIL/Apo2L) can be overcome by doxorubicin or adenoviral delivery of full-length TRAIL.Q43696432
Suppression of allogeneic T-cell proliferation by human marrow stromal cells: implications in transplantationQ44317237
Pre-existing immunity to adenovirus does not prevent tumor regression following intratumoral administration of a vector expressing IL-12 but inhibits virus disseminationQ45758816
Hexon-chimaeric adenovirus serotype 5 vectors circumvent pre-existing anti-vector immunityQ45857523
Decreased immune reactivity towards a knobless, affibody-targeted adenovirus type 5 vectorQ45863127
Gene transfer into the liver of nonhuman primates with E1-deleted recombinant adenoviral vectors: safety of readministrationQ45863202
Human mesenchymal stem cells lack tumor tropism but enhance the antitumor activity of oncolytic adenoviruses in orthotopic lung and breast tumorsQ45869203
Innate immune mechanisms dominate elimination of adenoviral vectors following in vivo administration.Q45880303
Human bone marrow-derived mesenchymal stem cells in the treatment of gliomasQ48926056
Gene transfer into rat mesenchymal stem cells: a comparative study of viral and nonviral vectors.Q50737303
Migration of Bone Marrow and Cord Blood Mesenchymal Stem Cells In Vitro Is Regulated by Stromal-Derived Factor-1-CXCR4 and Hepatocyte Growth Factor-c-met Axes and Involves Matrix MetalloproteinasesQ57375767
Apoptosis mediated by lentiviral TRAIL transfer involves transduction-dependent and -independent effectsQ57384572
Adenovirus-TRAIL can overcome TRAIL resistance and induce a bystander effectQ64377565
P433issue6B
P921main subjectmesenchymal stem cellQ1922379
lung cancerQ47912
P304page(s)2628-2643
P577publication date2008-03-28
P1433published inJournal of Cellular and Molecular MedicineQ1524063
P1476titleMesenchymal stem cells expressing TRAIL lead to tumour growth inhibition in an experimental lung cancer model
P478volume12

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