Decreased immune reactivity towards a knobless, affibody-targeted adenovirus type 5 vector

scientific article published on 12 October 2006

Decreased immune reactivity towards a knobless, affibody-targeted adenovirus type 5 vector is …
instance of (P31):
scholarly articleQ13442814

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P6179Dimensions Publication ID1005547818
P356DOI10.1038/SJ.GT.3302875
P698PubMed publication ID17036056
P5875ResearchGate publication ID6759408

P50authorPer-Ake NygrenQ33274230
P2093author name stringLindholm L
Olofsson S
Boulanger P
Hong SS
Myhre S
Henning P
Granio O
Tylö AS
P2860cites workIsolation of a common receptor for Coxsackie B viruses and adenoviruses 2 and 5Q28303765
Integrins alpha v beta 3 and alpha v beta 5 promote adenovirus internalization but not virus attachmentQ29615852
Affinity maturation of a Taq DNA polymerase specific affibody by helix shufflingQ30810400
Anti-idiotypic protein domains selected from protein A-based affibody librariesQ30835904
Immune response to recombinant capsid proteins of adenovirus in humans: antifiber and anti-penton base antibodies have a synergistic effect on neutralizing activity.Q33782487
Immune responses to adenovirus and adeno-associated virus in humans.Q33874473
Binding proteins selected from combinatorial libraries of an alpha-helical bacterial receptor domainQ34435244
Occupancy and mechanism in antibody-mediated neutralization of animal virusesQ34788252
On the mechanism of staphylococcal protein A immunomodulationQ36014924
Established immunity precludes adenovirus-mediated gene transfer in rat carotid arteries. Potential for immunosuppression and vector engineering to overcome barriers of immunityQ37362429
Monitoring foreign gene expression by a human adenovirus-based vector using the firefly luciferase gene as a reporterQ38566509
Immune response to recombinant adenovirus in humans: capsid components from viral input are targets for vector-specific cytotoxic T lymphocytesQ39592823
Binding of adenovirus capsid to dipalmitoyl phosphatidylcholine provides a novel pathway for virus entryQ39742044
Identification of adenovirus (ad) penton base neutralizing epitopes by use of sera from patients who had received conditionally replicative ad (addl1520) for treatment of liver tumorsQ40008652
Adenovirus stripping: a versatile method to generate adenovirus vectors with new cell target specificityQ40651696
Cryo-EM visualization of an exposed RGD epitope on adenovirus that escapes antibody neutralizationQ41120523
Genetic modification of adenovirus 5 tropism by a novel class of ligands based on a three-helix bundle scaffold derived from staphylococcal protein A.Q42050497
Adenoviruses with an RGD-4C modification of the fiber knob elicit a neutralizing antibody response but continue to allow enhanced gene deliveryQ45231506
Use of chimeric adenoviral vectors to assess capsid neutralization determinants.Q45274472
Genetic retargeting of adenovirus vectors: functionality of targeting ligands and their influence on virus viabilityQ45731708
Neutralisation of adenovirus infectivity by ascitic fluid from ovarian cancer patientsQ45867352
Incidence and prevalence of neutralizing antibodies to the common adenoviruses in children with cystic fibrosis: implication for gene therapy with adenovirus vectorsQ45887357
Neutralizing antibodies to adenovirus serotype 5 vaccine vectors are directed primarily against the adenovirus hexon proteinQ46499919
The 100K-chaperone protein from adenovirus serotype 2 (Subgroup C) assists in trimerization and nuclear localization of hexons from subgroups C and B adenovirusesQ46635220
Immunogenicity of recombinant adenovirus serotype 35 vaccine in the presence of pre-existing anti-Ad5 immunityQ47644096
Pre-existent adenovirus antibody inhibits systemic toxicity and antitumor activity of CN706 in the nude mouse LNCaP xenograft model: implications and proposals for human therapyQ64380528
P433issue4
P921main subjectAdenoviridaeQ193447
P304page(s)376-381
P577publication date2006-10-12
P1433published inGene TherapyQ15763095
P1476titleDecreased immune reactivity towards a knobless, affibody-targeted adenovirus type 5 vector
P478volume14

Reverse relations

cites work (P2860)
Q33565630Adenoviral vector immunity: its implications and circumvention strategies
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Q33279445Affibody molecules: potential for in vivo imaging of molecular targets for cancer therapy
Q33330736Alternative binding proteins: affibody binding proteins developed from a small three-helix bundle scaffold
Q37714826An easy method for preparation of Cre-loxP regulated fluorescent adenoviral expression vectors and its application for direct reprogramming into hepatocytes.
Q28744246Cell entry and trafficking of human adenovirus bound to blood factor X is determined by the fiber serotype and not hexon:heparan sulfate interaction
Q26995655Circumventing antivector immunity: potential use of nonhuman adenoviral vectors
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Q37310677Mesenchymal stem cells expressing TRAIL lead to tumour growth inhibition in an experimental lung cancer model
Q42155660Novel subventricular zone early progenitor cell-specific adenovirus for in vivo therapy of central nervous system disorders reinforces brain stem cell heterogeneity.
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