Interferon-β gene-modified human bone marrow mesenchymal stem cells attenuate hepatocellular carcinoma through inhibiting AKT/FOXO3a pathway

scientific article published on 25 July 2013

Interferon-β gene-modified human bone marrow mesenchymal stem cells attenuate hepatocellular carcinoma through inhibiting AKT/FOXO3a pathway is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.1038/BJC.2013.422
P932PMC publication ID3778282
P698PubMed publication ID23887606
P5875ResearchGate publication ID252325112

P2093author name stringC Xie
L Peng
Z-L Gao
P-P Wang
G-L Zhang
B-L Lin
D-Y Xie
P2860cites workControl of cell cycle exit and entry by protein kinase B-regulated forkhead transcription factorsQ24537205
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Cell cycle inhibition by FoxO forkhead transcription factors involves downregulation of cyclin D.Q39677789
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The expression and prognosis of FOXO3a and Skp2 in human hepatocellular carcinomaQ39858544
p38alpha blockade inhibits colorectal cancer growth in vivo by inducing a switch from HIF1alpha- to FoxO-dependent transcriptionQ39864596
Recombinant human IFN-beta affects androgen receptor level, neuroendocrine differentiation, cell adhesion, and motility in prostate cancer cellsQ40085697
Intrapulmonary IFN-beta gene therapy using an adenoviral vector is highly effective in a murine orthotopic model of bronchogenic adenocarcinoma of the lung.Q40372805
Inhibition of tumorigenicity and metastasis of human bladder cancer growing in athymic mice by interferon-beta gene therapy results partially from various antiangiogenic effects including endothelial cell apoptosis.Q40738912
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Why do so many cancer patients fail to respond to interferon therapy?Q41480595
Tumor-infiltrating macrophages are involved in suppressing growth and metastasis of human prostate cancer cells by INF-beta gene therapy in nude miceQ45854931
Antitumor effect of genetically engineered mesenchymal stem cells in a rat glioma modelQ45875290
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Human bone marrow-derived mesenchymal stem cells in the treatment of gliomasQ48926056
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Mesenchymal Stem Cells: Potential Precursors for Tumor Stroma and Targeted-Delivery Vehicles for Anticancer AgentsQ58828469
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Pharmacokinetics and pharmacodynamics of IFN-beta 1a in healthy volunteersQ73130450
Anti-tumor activity of mesenchymal stem cells producing IL-12 in a mouse melanoma modelQ79142180
FoxO3a mediates transforming growth factor-beta1-induced apoptosis in FaO rat hepatoma cellsQ79720153
Autologous bone marrow mesenchymal stem cell transplantation in liver failure patients caused by hepatitis B: short-term and long-term outcomesQ84184548
P433issue5
P407language of work or nameEnglishQ1860
P921main subjectbone marrowQ546523
hepatocellular carcinomaQ1148337
P304page(s)1198-1205
P577publication date2013-07-25
P1433published inBritish Journal of CancerQ326309
P1476titleInterferon-β gene-modified human bone marrow mesenchymal stem cells attenuate hepatocellular carcinoma through inhibiting AKT/FOXO3a pathway
P478volume109

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cites work (P2860)
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