Mesenchymal stem cells and their use as cell replacement therapy and disease modelling tool.

scientific article published on December 2008

Mesenchymal stem cells and their use as cell replacement therapy and disease modelling tool. is …
instance of (P31):
review articleQ7318358
scholarly articleQ13442814

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P356DOI10.1111/J.1582-4934.2008.00516.X
P932PMC publication ID3828873
P698PubMed publication ID19210755
P5875ResearchGate publication ID227606954

P50authorRene RodriguezQ37836712
Pablo MenendezQ38329307
Javier Garcia-castroQ43111748
P2093author name stringJ A Pérez-Simón
J Madrenas
C Trigueros
P2860cites workDerivation of sarcomas from mesenchymal stem cells via inactivation of the Wnt pathwayQ24298295
Molecular mechanisms for adaptive tolerance and other T cell anergy modelsQ24671646
Adult mesenchymal stem cells and cell-based tissue engineeringQ24796160
Stem cell niche: structure and functionQ28276131
Human mesenchymal stem cells modulate allogeneic immune cell responsesQ28288692
Tie2/angiopoietin-1 signaling regulates hematopoietic stem cell quiescence in the bone marrow nicheQ28505006
Mesenchymal stem cells within tumour stroma promote breast cancer metastasisQ29614303
Identification of the haematopoietic stem cell niche and control of the niche sizeQ29615008
Mesenchymal stem cells for treatment of steroid-resistant, severe, acute graft-versus-host disease: a phase II studyQ29617267
Treatment of severe acute graft-versus-host disease with third party haploidentical mesenchymal stem cellsQ29618766
Chondrogenic potential of human synovial mesenchymal stem cells in alginate.Q50468942
Potential risks of bone marrow cell transplantation into infarcted hearts.Q50685139
Allogeneic mesenchymal stem cell infusion for treatment of metachromatic leukodystrophy (MLD) and Hurler syndrome (MPS-IH).Q51953623
Preimplantation-stage stem cells induce long-term allogeneic graft acceptance without supplementary host conditioningQ45883050
The effect of mesenchymal stem cells on the viability, proliferation and differentiation of B-lymphocytes.Q46010474
Favorable response to human adipose tissue-derived mesenchymal stem cells in steroid-refractory acute graft-versus-host diseaseQ46843859
Sustained remissions of high-risk acute myeloid leukemia and myelodysplastic syndrome after reduced-intensity conditioning allogeneic hematopoietic transplantation: chronic graft-versus-host disease is the strongest factor improving survival.Q46845322
Autologous bone marrow stromal cells loaded onto porous hydroxyapatite ceramic accelerate bone repair in critical-size defects of sheep long bonesQ47250977
Effects of Wnt signaling on proliferation and differentiation of human mesenchymal stem cellsQ47424802
Expression of the EWS/FLI-1 oncogene in murine primary bone-derived cells Results in EWS/FLI-1-dependent, ewing sarcoma-like tumorsQ47605320
Susceptibility and resistance to antigen-induced apoptosis in the thymus of transgenic miceQ48032387
Wnt signaling regulates the invasion capacity of human mesenchymal stem cellsQ48088586
Human bone marrow-derived mesenchymal stem cells in the treatment of gliomasQ48926056
Mesenchymal stem cells are capable of homing to the bone marrow of non-human primates following systemic infusionQ49047090
Self-renewing osteoprogenitors in bone marrow sinusoids can organize a hematopoietic microenvironmentQ29620053
Graft-versus-host disease: a surge of developmentsQ33290423
Molecular characterization of spontaneous mesenchymal stem cell transformationQ33312958
Paracrine factors of mesenchymal stem cells recruit macrophages and endothelial lineage cells and enhance wound healingQ33326623
Transplantability and therapeutic effects of bone marrow-derived mesenchymal cells in children with osteogenesis imperfectaQ33855709
Therapeutic relevance of CD34 cell dose in blood cell transplantation for cancer therapyQ33861711
Development of Ewing's sarcoma from primary bone marrow-derived mesenchymal progenitor cellsQ33992270
Isolated allogeneic bone marrow-derived mesenchymal cells engraft and stimulate growth in children with osteogenesis imperfecta: Implications for cell therapy of boneQ34066339
Characterization of the expression of MHC proteins in human embryonic stem cellsQ34076010
CD3+CD4-CD8- alphabeta-TCR+ T cell as immune regulatory cellQ34340915
Interleukin-10-secreting type 1 regulatory T cells in rodents and humans.Q34569888
SSEA-4 identifies mesenchymal stem cells from bone marrowQ34576375
Differentiation of human mesenchymal stem cells and articular chondrocytes: analysis of chondrogenic potential and expression pattern of differentiation-related transcription factors.Q34577607
The Wnt signal transduction pathway in stem cells and cancer cells: influence on cellular invasion.Q34688333
Multiple tumor types may originate from bone marrow-derived cellsQ35082670
Pretransplant blood transfusions revisited: a role for CD(4+) regulatory T cells?Q35630658
Mesenchymal cells regulate the response of acute lymphoblastic leukemia cells to asparaginaseQ35677647
Clinical trials with adult stem/progenitor cells for tissue repair: let's not overlook some essential precautionsQ35751008
Donor-derived mesenchymal stem cells are immunogenic in an allogeneic host and stimulate donor graft rejection in a nonmyeloablative settingQ35849125
Understanding mesenchymal cancer: the liposarcoma-associated FUS-DDIT3 fusion gene as a modelQ36096576
Genetic manipulation of human embryonic stem cells: a system to study early human development and potential therapeutic applicationsQ36230369
Human mesenchymal stem cells exert potent antitumorigenic effects in a model of Kaposi's sarcomaQ36238078
Major histocompatibility complex class II-positive cortical epithelium mediates the selection of CD4(+)25(+) immunoregulatory T cellsQ36369536
The efficiency of CD4 recruitment to ligand-engaged TCR controls the agonist/partial agonist properties of peptide-MHC molecule ligandsQ36376752
Molecular regulation of T-cell anergyQ36466372
A developmental model of sarcomagenesis defines a differentiation-based classification for liposarcomas.Q36512275
Primer: mechanisms of immunologic toleranceQ36577410
Bone marrow mesenchymal stem cells are abnormal in multiple myelomaQ36593549
Human embryonic stem cells: potential tool for achieving immunotolerance?Q36672114
Cord-blood mesenchymal stem cells and tissue engineeringQ36712812
Wnt/beta-catenin signaling in cancer stemness and malignant behaviorQ36738603
New twists of T cell fate: control of T cell activation and tolerance by TGF-beta and NFAT.Q36791441
Advances in cell-based therapy for structural heart diseaseQ36820216
B-cell anergy: from transgenic models to naturally occurring anergic B cells?Q36887132
Tolerance induction in presensitized bone marrow recipients by veto CTLs: effective deletion of host anti-donor memory effector cells.Q51970080
Homeostatic expansion permits T cells to re-enter the thymus and deliver antigen in a tolerogenic fashion.Q51973805
Clonal mesenchymal progenitors from human bone marrow differentiate in vitro according to a hierarchical model.Q52170394
Human bone marrow derived mesenchymal stem cells do not undergo transformation after long-term in vitro culture and do not exhibit telomere maintenance mechanisms.Q53328521
Expression of the FUS-CHOP fusion protein in primary mesenchymal progenitor cells gives rise to a model of myxoid liposarcoma.Q53343855
Accumulated chromosomal instability in murine bone marrow mesenchymal stem cells leads to malignant transformation.Q53352599
Spontaneous human adult stem cell transformation.Q53358878
EWS-FLI-1 expression triggers a Ewing's sarcoma initiation program in primary human mesenchymal stem cells.Q53487773
Requirement for T-cell apoptosis in the induction of peripheral transplantation tolerance.Q54073234
Induction of peripheral T cell tolerance in vivo requires CTLA-4 engagement.Q54308518
Zebrafish fins as a model system for skeletal human studies.Q55048845
CTLA-4 regulates induction of anergy in vivoQ56905417
Mesenchymal Stem Cells: Potential Precursors for Tumor Stroma and Targeted-Delivery Vehicles for Anticancer AgentsQ58828469
Bone marrow mesenchymal stem cells induce division arrest anergy of activated T cellsQ59102107
Human mesenchymal stem cells inhibit differentiation and function of monocyte-derived dendritic cellsQ61645531
Mesenchymal Stem Cells for Treatment of Therapy-Resistant Graft-versus-Host DiseaseQ63197317
Mesenchymal stem cells: potential precursors for tumor stroma and targeted-delivery vehicles for anticancer agentsQ64379193
Osteogenesis in transplants of bone marrow cellsQ71202383
Donor leukocyte infusions in 140 patients with relapsed malignancy after allogeneic bone marrow transplantationQ73117300
Rapid hematopoietic recovery after coinfusion of autologous-blood stem cells and culture-expanded marrow mesenchymal stem cells in advanced breast cancer patients receiving high-dose chemotherapyQ73358706
Identification of a previously unknown antigen-specific regulatory T cell and its mechanism of suppressionQ73977252
Pre-transplant blood transfusion and renal allograft outcome: a report of the North American Pediatric Renal Transplant Cooperative StudyQ74619623
T-cell anergy and altered T-cell receptor signaling: effects on autoimmune diseaseQ77454764
Thymic re-entry of mature activated T cells and increased negative selection in vascularized allograft recipientsQ77737333
Influence of the different CD34+ and CD34- cell subsets infused on clinical outcome after non-myeloablative allogeneic peripheral blood transplantation from human leucocyte antigen-identical sibling donorsQ78311697
Nonhematopoietic/endothelial SSEA-1+ cells define the most primitive progenitors in the adult murine bone marrow mesenchymal compartmentQ79143613
HLA expression and immunologic propertiesof differentiated and undifferentiated mesenchymal stem cellsQ79149793
Presence of mesenchymal stem cells in human bone marrow after exposure to chemotherapy: evidence of resistance to apoptosis inductionQ80165361
Transplantation of mesenchymal stem cells to enhance engraftment of hematopoietic stem cellsQ80413361
The correlation between cotransplantation of mesenchymal stem cells and higher recurrence rate in hematologic malignancy patients: outcome of a pilot clinical studyQ80471824
Human mesenchymal stem cell transformation is associated with a mesenchymal-epithelial transitionQ80507318
Tissue repair using allogeneic mesenchymal stem cells for hemorrhagic cystitis, pneumomediastinum and perforated colonQ80568647
Bone marrow stromal cell-derived Wnt signals as a potential underlying mechanism for cyclin D1 deregulation in multiple myeloma lacking t(11;14)(q13;q32)Q80614725
Gastric cancer originating from bone marrow-derived cellsQ81067451
Maintenance of B cell anergy requires constant antigen receptor occupancy and signalingQ81299785
Integration of Notch and Wnt signaling in hematopoietic stem cell maintenanceQ81308407
Cotransplantation of HLA-identical sibling culture-expanded mesenchymal stem cells and hematopoietic stem cells in hematologic malignancy patientsQ81676895
Reduced-intensity conditioning allogeneic transplantation is associated with a high incidence of extramedullary relapses in multiple myeloma patientsQ82242208
Bone marrow mesenchymal stem cells chimerism after allogeneic hematopoietic transplantationQ82264274
Apoptosis during negative selection of autoreactive thymocytesQ36893056
Immune tolerance: mechanisms and application in clinical transplantationQ36909564
Human stem cells for CNS repair.Q36954408
Immunomodulation by mesenchymal stem cells and clinical experienceQ36975987
Dendritic cell therapy for tolerance induction to stem cell transplants.Q37066434
Cancer stem cells--old concepts, new insights.Q37079713
The Foxp3+ regulatory T cell: a jack of all trades, master of regulationQ37088900
Inflammation and tumor microenvironments: defining the migratory itinerary of mesenchymal stem cellsQ37134013
The bone marrow microenvironment as a tumor sanctuary and contributor to drug resistanceQ37152481
Stem cell regeneration of degenerated intervertebral discs: current statusQ37161478
Technology insight: adult mesenchymal stem cells for osteoarthritis therapyQ37163015
Mesenchymal stromal cells: a novel treatment option for steroid-induced avascular osteonecrosis.Q37169425
Long-term in vitro expansion alters the biology of adult mesenchymal stem cellsQ37269767
Mesenchymal stem cells expressing TRAIL lead to tumour growth inhibition in an experimental lung cancer modelQ37310677
Interleukin 2 production, not the pattern of early T-cell antigen receptor-dependent tyrosine phosphorylation, controls anergy induction by both agonists and partial agonistsQ37362068
Mesenchymal stem cells as a vehicle for targeted delivery of CRAds to lung metastases of breast carcinomaQ38507328
Suppression of tumorigenesis by human mesenchymal stem cells in a hepatoma modelQ39998770
The growth inhibitory effect of mesenchymal stem cells on tumor cells in vitro and in vivoQ40039805
Spontaneous expression of embryonic factors and p53 point mutations in aged mesenchymal stem cells: a model of age-related tumorigenesis in miceQ40050583
Mesenchymal stem cells share molecular signature with mesenchymal tumor cells and favor early tumor growth in syngeneic miceQ40052794
Electron microscopy reveals the presence of viruses in mouse embryonic fibroblasts but neither in human embryonic fibroblasts nor in human mesenchymal cells used for hESC maintenance: toward an implementation of microbiological quality assurance proQ40128166
In vitro transformation of mesenchymal stem cells by oncogenic H-rasVal12.Q40195027
Earlier onset of syngeneic tumors in the presence of mesenchymal stem cellsQ40216419
Sarcoma derived from cultured mesenchymal stem cellsQ40220522
T cell anergy is reversed by active Ras and is regulated by diacylglycerol kinase-alphaQ40222415
Outgrowth of a transformed cell population derived from normal human BM mesenchymal stem cell culture.Q40348177
Adult human mesenchymal stem cell as a target for neoplastic transformationQ40563067
Gene-enhanced tissue engineering: applications for bone healing using cultured periosteal cells transduced retrovirally with the BMP-7 gene.Q40952287
Identification of stromal cell precursors in human bone marrow by a novel monoclonal antibody, STRO-1.Q41675626
Calcium phosphate surfaces promote osteogenic differentiation of mesenchymal stem cellsQ41969492
Immunosuppressive therapy and tolerance of organ allograftsQ42365619
Cotransplantation of ex vivo expanded mesenchymal stem cells accelerates lymphocyte recovery and may reduce the risk of graft failure in haploidentical hematopoietic stem-cell transplantationQ44746492
Mesenchymal stem cells for graft-versus-host disease: a double edged sword?Q44786836
Adipose tissue-derived mesenchymal stem cells have in vivo immunosuppressive properties applicable for the control of the graft-versus-host diseaseQ45861396
Propagation and senescence of human marrow stromal cells in culture: a simple colony-forming assay identifies samples with the greatest potential to propagate and differentiateQ45863683
Gene therapy and stem cell therapy for cardiovascular diseases today: a model for translational researchQ45865166
Human mesenchymal stem cells lack tumor tropism but enhance the antitumor activity of oncolytic adenoviruses in orthotopic lung and breast tumorsQ45869203
Human mesenchymal stem cells alter antigen-presenting cell maturation and induce T-cell unresponsivenessQ45879145
P433issue6B
P921main subjectmesenchymal stem cellQ1922379
cellQ7868
biomedical investigative techniqueQ66648976
P304page(s)2552-2565
P577publication date2008-12-01
P1433published inJournal of Cellular and Molecular MedicineQ1524063
P1476titleMesenchymal stem cells and their use as cell replacement therapy and disease modelling tool
P478volume12

Reverse relations

cites work (P2860)
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