Concise Review: Mesenchymal Stem Cells Ameliorate Tissue Injury via Secretion of Tumor Necrosis Factor-α Stimulated Protein/Gene 6.

scientific article published on 15 December 2014

Concise Review: Mesenchymal Stem Cells Ameliorate Tissue Injury via Secretion of Tumor Necrosis Factor-α Stimulated Protein/Gene 6. is …
instance of (P31):
review articleQ7318358
scholarly articleQ13442814

External links are
P356DOI10.1155/2014/761091
P932PMC publication ID4279254
P698PubMed publication ID25580135
P5875ResearchGate publication ID270907139

P2093author name stringZhigang He
Zhenshun Song
Jie Hua
P2860cites workA novel secretory tumor necrosis factor-inducible protein (TSG-6) is a member of the family of hyaluronate binding proteins, closely related to the adhesion receptor CD44Q24297519
Human multipotent stromal cells attenuate lipopolysaccharide-induced acute lung injury in mice via secretion of tumor necrosis factor-α-induced protein 6Q24302245
Mesenchymal stem cell secretes microparticles enriched in pre-microRNAsQ24651962
Gene expression induced by interleukin-17 in fibroblast-like synoviocytes of patients with rheumatoid arthritis: upregulation of hyaluronan-binding protein TSG-6Q24804836
Multilineage potential of adult human mesenchymal stem cellsQ27860737
Concise review: mesenchymal stem/multipotent stromal cells: the state of transdifferentiation and modes of tissue repair--current viewsQ28251015
TSG-6, an arthritis-associated hyaluronan binding protein, forms a stable complex with the serum protein inter-alpha-inhibitorQ28286255
Human mesenchymal stem cells modulate allogeneic immune cell responsesQ28288692
Mesenchymal stem cells attenuate peritoneal injury through secretion of TSG-6Q28566510
Microvesicles derived from adult human bone marrow and tissue specific mesenchymal stem cells shuttle selected pattern of miRNAsQ28750201
DAMPs, PAMPs and alarmins: all we need to know about dangerQ29547535
Mesenchymal stem cells in health and diseaseQ29614296
Circulating mitochondrial DAMPs cause inflammatory responses to injuryQ29614470
Mesenchymal stem cellsQ29619804
Mesenchymal stem cells as trophic mediatorsQ29619806
Paracrine mechanisms in adult stem cell signaling and therapyQ29620571
Intravenous hMSCs improve myocardial infarction in mice because cells embolized in lung are activated to secrete the anti-inflammatory protein TSG-6Q29620590
Comparative analysis of mesenchymal stem cells from bone marrow, umbilical cord blood, or adipose tissueQ29620725
Administration of TSG-6 improves memory after traumatic brain injury in mice.Q30548200
Myocardial infarction and remodeling in mice: effect of reperfusionQ33178763
Paracrine factors of mesenchymal stem cells recruit macrophages and endothelial lineage cells and enhance wound healingQ33326623
Stem cell paracrine actions and tissue regenerationQ33708216
Mesenchymal stem cell therapy: Two steps forward, one step backQ33898653
Isolation and characterization of eight tumor necrosis factor-induced gene sequences from human fibroblastsQ33989008
Marrow stromal cells form guiding strands in the injured spinal cord and promote recoveryQ34012747
Isolated allogeneic bone marrow-derived mesenchymal cells engraft and stimulate growth in children with osteogenesis imperfecta: Implications for cell therapy of boneQ34066339
The link module from human TSG-6 inhibits neutrophil migration in a hyaluronan- and inter-alpha -inhibitor-independent manner.Q34156381
Anti-inflammatory protein TSG-6 reduces inflammatory damage to the cornea following chemical and mechanical injury.Q34165745
Therapeutic potential of mesenchymal stem cells for severe acute lung injuryQ34184246
TSG-6: a multifunctional protein associated with inflammationQ34190264
Mesenchymal stem cells: building blocks for molecular medicine in the 21st centuryQ34265135
Mesenchymal stem cellsQ34275859
TNF/IL-1-inducible protein TSG-6 potentiates plasmin inhibition by inter-alpha-inhibitor and exerts a strong anti-inflammatory effect in vivoQ34372188
The TSG-6 and I alpha I interaction promotes a transesterification cleaving the protein-glycosaminoglycan-protein (PGP) cross-link.Q34384870
TSG-6: an IL-1/TNF-inducible protein with anti-inflammatory activityQ34434369
TSG-6: a pluripotent inflammatory mediator?Q34527768
Tissue injury in inflammation. Oxidants, proteinases, and cationic proteinsQ34562547
Anti-inflammatory protein TSG-6 secreted by activated MSCs attenuates zymosan-induced mouse peritonitis by decreasing TLR2/NF-κB signaling in resident macrophages.Q35112231
The MSC: an injury drugstoreQ35130445
Mesenchymal stem cell engraftment in lung is enhanced in response to bleomycin exposure and ameliorates its fibrotic effectsQ35168236
Activity-dependent neuronal plasticity following tissue injury and inflammationQ35315392
Mesenchymal stem/stromal cells (MSCs): role as guardians of inflammationQ35665181
Mesenchymal stem cells (MSC) as therapeutic cytoreagents for gene therapy.Q36072501
Comparative analysis of paracrine factor expression in human adult mesenchymal stem cells derived from bone marrow, adipose, and dermal tissueQ36138509
Intravenous mesenchymal stem cells prevented rejection of allogeneic corneal transplants by aborting the early inflammatory responseQ36401080
TSG-6 protein is crucial for the development of pulmonary hyaluronan deposition, eosinophilia, and airway hyperresponsiveness in a murine model of asthmaQ36508659
TSG-6: a TNF-, IL-1-, and LPS-inducible secreted glycoprotein associated with arthritisQ36756311
The magic glue hyaluronan and its eraser hyaluronidase: a biological overviewQ36780289
TSG-6 produced by hMSCs delays the onset of autoimmune diabetes by suppressing Th1 development and enhancing tolerogenicityQ36867533
Adult mesenchymal stem cells for tissue engineering versus regenerative medicine.Q36874456
Bone marrow-derived mesenchymal stem cells for treatment of heart failure: is it all paracrine actions and immunomodulation?Q37056142
Mesenchymal stem cell-derived microvesicles protect against acute tubular injuryQ37176871
Mesenchymal stem cells and their use as cell replacement therapy and disease modelling tool.Q37390890
DAMPs and inflammatory processes: the role of redox in the different outcomesQ37535386
Phase-directed therapy: TSG-6 targeted to early inflammation improves bleomycin-injured lungsQ37576082
Modification of hyaluronan by heavy chains of inter-α-inhibitor in idiopathic pulmonary arterial hypertensionQ37622593
Mesenchymal stem cells transplantation suppresses inflammatory responses in global cerebral ischemia: contribution of TNF-α-induced protein 6.Q37729080
The immunomodulatory properties of mesenchymal stem cellsQ37866167
Role of mesenchymal stem cell therapy in Crohn's diseaseQ37995012
Paracrine mechanisms of mesenchymal stem cell-based therapy: current status and perspectives.Q38107063
Localization and characterization of the hyaluronan-binding site on the link module from human TSG-6.Q38310376
Oxygen radicals, inflammation, and tissue injuryQ39581083
Interactions between human mesenchymal stem cells and natural killer cellsQ40385365
Gene expression profile of cytokine and growth factor during differentiation of bone marrow-derived mesenchymal stem cellQ40419310
Macrophages and inflammatory mediators in tissue injuryQ40437032
Chemokines and tissue injuryQ40543142
Cartilage link protein interacts with neurocan, which shows hyaluronan binding characteristics different from CD44 and TSG-6.Q40570446
TSG-6 modulates the interaction between hyaluronan and cell surface CD44.Q40570782
Tissue injury in neutrophilic inflammationQ41645304
A successful collagenase and hyaluronic Acid topical use combined with antibiotic therapy in the treatment of ulcerative lesions arising on tattooQ42255243
Hyaluronan binding properties of a CD44 chimera containing the link module of TSG-6.Q43993812
Mesenchymal stem cells enhance the viability and proliferation of human fetal intestinal epithelial cells following hypoxic injury via paracrine mechanisms.Q45921794
Adult human mesenchymal stem cells added to corticosteroid therapy for the treatment of acute graft-versus-host disease.Q45962719
Expression of tumor necrosis factor-alpha stimulated gene-6 mRNA in cultured human uterine cervical fibroblastsQ46606118
TSG-6 released from intradermally injected mesenchymal stem cells accelerates wound healing and reduces tissue fibrosis in murine full-thickness skin woundsQ47842516
Vasculotropic, paracrine actions of infused mesenchymal stem cells are important to the recovery from acute kidney injury.Q51085218
IGF-1-overexpressing mesenchymal stem cells accelerate bone marrow stem cell mobilization via paracrine activation of SDF-1alpha/CXCR4 signaling to promote myocardial repair.Q51677233
Heterotopic of bone marrow. Analysis of precursor cells for osteogenic and hematopoietic tissuesQ53745526
Acute myocardial infarctionQ54069247
Up-regulation and differential expression of the hyaluronan-binding protein TSG-6 in cartilage and synovium in rheumatoid arthritis and osteoarthritisQ60505217
Acute myocardial infarctionQ73138978
Human marrow-derived mesenchymal stem cells (MSCs) express hematopoietic cytokines and support long-term hematopoiesis when differentiated toward stromal and osteogenic lineagesQ73438633
Identification of CD44 residues important for hyaluronan binding and delineation of the binding siteQ73996059
Sleuthing the source of regeneration by MSCsQ84153511
Action at a distance: systemically administered adult stem/progenitor cells (MSCs) reduce inflammatory damage to the cornea without engraftment and primarily by secretion of TNF-α stimulated gene/protein 6Q84753164
P275copyright licenseCreative Commons Attribution 3.0 UnportedQ14947546
P6216copyright statuscopyrightedQ50423863
P921main subjectmesenchymal stem cellQ1922379
P304page(s)761091
P577publication date2014-12-15
P1433published inStem Cells InternationalQ26842114
P1476titleConcise Review: Mesenchymal Stem Cells Ameliorate Tissue Injury via Secretion of Tumor Necrosis Factor-α Stimulated Protein/Gene 6.
P478volume2014

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cites work (P2860)
Q47808641Bone marrow mesenchymal stem cells ameliorate lung injury through anti-inflammatory and antibacterial effect in COPD mice
Q37649042Mesenchymal stem cells alleviate Japanese encephalitis virus-induced neuroinflammation and mortality.
Q55311906Sphingosine 1-Phosphate Receptor 1 Is Required for MMP-2 Function in Bone Marrow Mesenchymal Stromal Cells: Implications for Cytoskeleton Assembly and Proliferation.

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