Mesenchymal stem cell therapy: Two steps forward, one step back

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Mesenchymal stem cell therapy: Two steps forward, one step back is …
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scholarly articleQ13442814

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P356DOI10.1016/J.MOLMED.2010.02.005
P8608Fatcat IDrelease_7cfyktzdfrg5nnreu7ucr25snq
P932PMC publication ID2881950
P698PubMed publication ID20335067
P5875ResearchGate publication ID42541261

P50authorJames A AnkrumQ62577277
P2093author name stringJeffrey M Karp
James Ankrum
P2860cites workRegenerating the heartQ22251075
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Ex vivo glycan engineering of CD44 programs human multipotent mesenchymal stromal cell trafficking to boneQ28264546
Mesenchymal stem cells for treatment of steroid-resistant, severe, acute graft-versus-host disease: a phase II studyQ29617267
Mesenchymal stem cells reside in virtually all post-natal organs and tissuesQ29617740
Treatment of severe acute graft-versus-host disease with third party haploidentical mesenchymal stem cellsQ29618766
Human bone marrow stromal cells suppress T-lymphocyte proliferation induced by cellular or nonspecific mitogenic stimuliQ29618769
Bone marrow stromal cells attenuate sepsis via prostaglandin E(2)-dependent reprogramming of host macrophages to increase their interleukin-10 productionQ29619807
Intravenous hMSCs improve myocardial infarction in mice because cells embolized in lung are activated to secrete the anti-inflammatory protein TSG-6Q29620590
Dynamic imaging of allogeneic mesenchymal stem cells trafficking to myocardial infarctionQ30477220
In vivo imaging of specialized bone marrow endothelial microdomains for tumour engraftmentQ30484167
Live-animal tracking of individual haematopoietic stem/progenitor cells in their nicheQ30493093
Fate of culture-expanded mesenchymal stem cells in the microvasculature: in vivo observations of cell kineticsQ30541132
Intracoronary bone marrow cell transfer after myocardial infarction: eighteen months' follow-up data from the randomized, controlled BOOST (BOne marrOw transfer to enhance ST-elevation infarct regeneration) trialQ31033745
Why are MSCs therapeutic? New data: new insight.Q33386080
Imaging molecular expression on vascular endothelial cells by in vivo immunofluorescence microscopyQ33571085
Repair of tissues by adult stem/progenitor cells (MSCs): controversies, myths, and changing paradigmsQ33713663
Direct evidence of mesenchymal stem cell tropism for tumor and wounding microenvironments using in vivo bioluminescent imagingQ34162598
Trafficking mesenchymal stem cell engraftment and differentiation in tumor-bearing mice by bioluminescence imagingQ34164696
Fibroblast precursors in normal and irradiated mouse hematopoietic organsQ34474362
TSG-6: a pluripotent inflammatory mediator?Q34527768
Mesenchymal stem cells and their potential as cardiac therapeuticsQ35830869
Interleukin 1 receptor antagonist mediates the antiinflammatory and antifibrotic effect of mesenchymal stem cells during lung injuryQ35841729
A randomized, double-blind, placebo-controlled, dose-escalation study of intravenous adult human mesenchymal stem cells (prochymal) after acute myocardial infarctionQ36634299
From the laboratory bench to the patient's bedside: an update on clinical trials with mesenchymal stem cellsQ36709408
Immunomodulatory properties of mesenchymal stromal cellsQ36896799
Mesenchymal stem cells: revisiting history, concepts, and assays.Q37036368
The CD34-like protein PODXL and alpha6-integrin (CD49f) identify early progenitor MSCs with increased clonogenicity and migration to infarcted heart in miceQ37071096
Inflammation and tumor microenvironments: defining the migratory itinerary of mesenchymal stem cellsQ37134013
Allogeneic mesenchymal stem cells restore cardiac function in chronic ischemic cardiomyopathy via trilineage differentiating capacity.Q37310724
Mesenchymal stem cell homing: the devil is in the detailsQ37407769
Autologous mesenchymal stem cells produce reverse remodelling in chronic ischaemic cardiomyopathyQ37420332
Optimizing mesenchymal stem cell-based therapeutics.Q37604019
Labeling of mesenchymal stem cells by bioconjugated quantum dotsQ39978227
Role of paracrine factors in stem and progenitor cell mediated cardiac repair and tissue fibrosisQ41940674
Multipotent human stromal cells improve cardiac function after myocardial infarction in mice without long-term engraftmentQ42853310
The dynamic in vivo distribution of bone marrow-derived mesenchymal stem cells after infusion.Q43599448
Systemic delivery of bone marrow-derived mesenchymal stem cells to the infarcted myocardium: feasibility, cell migration, and body distribution.Q44538164
Stem cell transplantation: the lung barrier.Q46028067
In vivo magnetic resonance imaging of mesenchymal stem cells in myocardial infarctionQ50765152
Vasculotropic, paracrine actions of infused mesenchymal stem cells are important to the recovery from acute kidney injuryQ51085218
Bone marrow mesenchymal stem cells inhibit the response of naive and memory antigen-specific T cells to their cognate peptide.Q52008649
Improvement of cardiac function after transplantation of autologous bone marrow mesenchymal stem cells in patients with acute myocardial infarction.Q53606669
Seeding efficiency of primitive human hematopoietic cells in nonobese diabetic/severe combined immune deficiency mice: implications for stem cell frequency assessmentQ73168627
Bone marrow cell trafficking following intravenous administrationQ73293668
Mesenchymal stem cells modified with Akt prevent remodeling and restore performance of infarcted heartsQ73791469
Primary murine MSC show highly efficient homing to the bone marrow but lose homing ability following cultureQ78800357
Distribution of circulation-derived endothelial progenitors following systemic deliveryQ79963887
Mesenchymal stem cells display coordinated rolling and adhesion behavior on endothelial cellsQ80077858
P433issue5
P921main subjectmesenchymal stem cellQ1922379
P304page(s)203-209
P577publication date2010-03-23
P1433published inTrends in Molecular MedicineQ15265842
P1476titleMesenchymal stem cell therapy: Two steps forward, one step back
P478volume16

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