Why are MSCs therapeutic? New data: new insight.

scientific article

Why are MSCs therapeutic? New data: new insight. is …
instance of (P31):
review articleQ7318358
scholarly articleQ13442814

External links are
P356DOI10.1002/PATH.2469
P698PubMed publication ID19023885
P5875ResearchGate publication ID23487858

P50authorArnold CaplanQ56233365
P2093author name stringA I Caplan
P433issue2
P304page(s)318-324
P577publication date2009-01-01
P1433published inJournal of PathologyQ400296
P1476titleWhy are MSCs therapeutic? New data: new insight
P478volume217

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Q37678413More insight into mesenchymal stem cells and their effects inside the body
Q50951146Multipotent bone marrow stromal cell therapy promotes endogenous cell proliferation following ischemic stroke.
Q35369603Multipotent mesenchymal stromal stem cell expansion by plating whole bone marrow at a low cellular density: a more advantageous method for clinical use
Q34429321Myogenic potential of whole bone marrow mesenchymal stem cells in vitro and in vivo for usage in urinary incontinence
Q35860306Nestin Positive Bone Marrow Derived Cells Responded to Injury Mobilize into Peripheral Circulation and Participate in Skin Defect Healing
Q26765840Neuromuscular Regeneration: Perspective on the Application of Mesenchymal Stem Cells and Their Secretion Products
Q34978132New Frontiers for Cartilage Repair and Protection
Q34513159New concepts on the immune modulation mediated by mesenchymal stem cells
Q33532634Non-invasive stem cell therapy in a rat model for retinal degeneration and vascular pathology
Q43616044Nonviral gene delivery of erythropoietin by mesenchymal stromal cells
Q43113201One-Step Cartilage Repair with Bone Marrow Aspirate Concentrated Cells and Collagen Matrix in Full-Thickness Knee Cartilage Lesions: Results at 2-Year Follow-up.
Q30529826Optimization and scale-up culture of human endometrial multipotent mesenchymal stromal cells: potential for clinical application.
Q36202472Optimization of adipose tissue-derived mesenchymal stem cells by rapamycin in a murine model of acute graft-versus-host disease
Q91845563Optimization of photocrosslinked gelatin/hyaluronic acid hybrid scaffold for the repair of cartilage defect
Q38982831Optimizing stem cells for cardiac repair: Current status and new frontiers in regenerative cardiology
Q35305543Organ specific regenerative markers in peri-organ adipose: kidney
Q96022699Oriented immobilization of basic fibroblast growth factor: Bioengineered surface design for the expansion of human mesenchymal stromal cells
Q89359657Origin of Reparative Stem Cells in Fracture Healing
Q37930522Osteochondral tissue engineering approaches for articular cartilage and subchondral bone regeneration.
Q36142956Overexpression of Glutamate Decarboxylase in Mesenchymal Stem Cells Enhances Their Immunosuppressive Properties and Increases GABA and Nitric Oxide Levels.
Q48496494Oxygen-Glucose Deprivation Induces G2/M Cell Cycle Arrest in Brain Pericytes Associated with ERK Inactivation
Q51666542Parameters of Microcirculation in the Broad Ligament of the Uterus in Wistar Rats after Injection of Autologous Biomedical Cell Product.
Q35778584Patterns of amino acid metabolism by proliferating human mesenchymal stem cells
Q47296829Pentosan polysulfate binds to STRO-1+ mesenchymal progenitor cells, is internalized, and modifies gene expression: a novel approach of pre-programing stem cells for therapeutic application requiring their chondrogenesis
Q37788221Perivascular cells as mesenchymal stem cells
Q37095242Perivascular cells in blood vessel regeneration
Q38078084Perivascular mesenchymal stem cells in the adult human brain: a future target for neuroregeneration?
Q54453404Pigment epithelium-derived factor delays cellular senescence of human mesenchymal stem cells in vitro by reducing oxidative stress.
Q37676215Platelet-derived growth factor receptors regulate mesenchymal stem cell fate: implications for neovascularization
Q39030538Poly(γ-Glutamic Acid) as an Exogenous Promoter of Chondrogenic Differentiation of Human Mesenchymal Stem/Stromal Cells
Q39145866Positive selection of Wharton's jelly-derived CD105(+) cells by MACS technique and their subsequent cultivation under suspension culture condition: A simple, versatile culturing method to enhance the multipotentiality of mesenchymal stem cells
Q26765276Potential mechanisms underlying the Runx2 induced osteogenesis of bone marrow mesenchymal stem cells
Q38071770Potential role of mesenchymal stromal cells in pancreatic islet transplantation
Q34479398Potential therapeutic applications of muscle-derived mesenchymal stem and progenitor cells
Q50937752Pre-Treatment of Human Mesenchymal Stem Cells With Inflammatory Factors or Hypoxia Does Not Influence Migration to Osteoarthritic Cartilage and Synovium.
Q36046310Preclinical Studies of Mesenchymal Stem Cell (MSC) Administration in Chronic Obstructive Pulmonary Disease (COPD): A Systematic Review and Meta-Analysis
Q35655462Preconditioning of mesenchymal stem cells for improved transplantation efficacy in recessive dystrophic epidermolysis bullosa
Q34131282Prospect of cell therapy for Parkinson's disease
Q35552862Pullulan: a new cytoadhesive for cell-mediated cartilage repair.
Q99415670Pulsed focused ultrasound enhances the therapeutic effect of mesenchymal stromal cell-derived extracellular vesicles in acute kidney injury
Q42277124Quantification of Mesenchymal Stem Cells (MSCs) at sites of human prostate cancer
Q59800140Quantitative assessment of mesenchymal stem cells contained in concentrated autologous bone marrow aspirate transplantation for the treatment of osteonecrosis of the femoral head: predictive factors and differences by etiology
Q33796581Radiation rescue: mesenchymal stromal cells protect from lethal irradiation
Q36867662Rapid selection of mesenchymal stem and progenitor cells in primary prostate stromal cultures
Q27314509Rapidly self-renewing human multipotent marrow stromal cells (hMSC) express sialyl Lewis X and actively adhere to arterial endothelium in a chick embryo model system
Q38282065Rationale for the potential use of mesenchymal stromal cells in liver transplantation
Q36928797Regenerative medicine in 2012: the coming of age of musculoskeletal tissue engineering
Q38133660Regenerative medicine: prospects for the treatment of inflammatory bowel disease.
Q37041753Reiterated Targeting Peptides on the Nanoparticle Surface Significantly Promote Targeted Vascular Endothelial Growth Factor Gene Delivery to Stem Cells.
Q36733945Relevance of brown adipose tissue in infancy and adolescence
Q56978588Response of encapsulated cells to a gelatin matrix with varied bulk and microenvironmental elastic properties
Q94453499Reversing Acute Kidney Injury Using Pulsed Focused Ultrasound and MSC Therapy: A Role for HSP-Mediated PI3K/AKT Signaling
Q39017821Review article: mesenchymal stromal cell therapy for inflammatory bowel diseases
Q88395107Rheological characterization of dynamic remodeling of the pericellular region by human mesenchymal stem cell-secreted enzymes in well-defined synthetic hydrogel scaffolds
Q26865460Roles of microRNAs in prenatal chondrogenesis, postnatal chondrogenesis and cartilage-related diseases
Q37523447Rotator cuff repair augmentation in a rat model that combines a multilayer xenograft tendon scaffold with bone marrow stromal cells
Q64947688Safety and Efficacy of Adult Stem Cell Therapy for Acute Myocardial Infarction and Ischemic Heart Failure (SafeCell Heart): A Systematic Review and Meta-Analysis.
Q33863334Safety and Feasibility of Autologous Mesenchymal Stem Cell Transplantation in Chronic Stroke in Indian patients. A four-year follow up
Q34469147Safety of cell therapy with mesenchymal stromal cells (SafeCell): a systematic review and meta-analysis of clinical trials
Q35997373Safety of mesenchymal stem cells for clinical application
Q42542515Salient features of mesenchymal stem cells-implications for Ewing sarcoma modeling
Q30010051Scaling-up of dental pulp stem cells isolated from multiple niches
Q54271815Scleroderma Mesenchymal Stem Cells display a different phenotype from healthy controls; implications for regenerative medicine.
Q35169389Scx-transduced tendon-derived stem cells (tdscs) promoted better tendon repair compared to mock-transduced cells in a rat patellar tendon window injury model
Q37868851Selecting the optimal cell for kidney regeneration: fetal, adult or reprogrammed stem cells.
Q38034154Separation technologies for stem cell bioprocessing.
Q42664619Sequential exposure to fibroblast growth factors (FGF) 2, 9 and 18 enhances hMSC chondrogenic differentiation
Q93092814Short-term results (1 year) of vented versus solid polyetheretherketone anchors in treatment of rotator cuff tears
Q54958005Sizes and Sufficient Quantities of MSC Microspheres for Intrathecal Injection to Modulate Inflammation in Spinal Cord Injury.
Q36797513Skeletal ligament healing using the recombinant human amelogenin protein
Q36806575Soft Elasticity-Associated Signaling and Bone Morphogenic Protein 2 Are Key Regulators of Mesenchymal Stem Cell Spheroidal Aggregates
Q42019222Sonic hedgehog (SHH) signaling improves the angiogenic potential of Wharton's jelly-derived mesenchymal stem cells (WJ-MSC).
Q27333151Spatial organization of mesenchymal stem cells in vitro--results from a new individual cell-based model with podia
Q27023276Spheroid Culture of Mesenchymal Stem Cells
Q85482841Stability of human mesenchymal stem cells during in vitro culture: considerations for cell therapy
Q94527898Status, challenges, and future prospects of stem cell therapy in pelvic floor disorders
Q57288362Stem Cell Therapy in Cerebrovascular Disease
Q35840661Stem cell applications in military medicine
Q34111083Stem cell approaches for the treatment of type 1 diabetes mellitus
Q33708216Stem cell paracrine actions and tissue regeneration
Q33605311Stem cell therapies for knee cartilage repair: the current status of preclinical and clinical studies
Q38601272Stem cell therapy for cardiac regeneration: hits and misses.
Q34419548Stem cell-based treatments against stroke: observations from human proof-of-concept studies and considerations regarding clinical applicability
Q35877941Stem cell-derived extracellular matrix enables survival and multilineage differentiation within superporous hydrogels.
Q35980472Stem cells and bFGF in tendon healing: Effects of lentiviral gene transfer and long-term follow-up in a rat Achilles tendon defect model
Q35849847Stem cells in dental pulp of deciduous teeth.
Q38630465Stem cells therapy for ALS.
Q34614799Stromal cell-derived factor-1β mediates cell survival through enhancing autophagy in bone marrow-derived mesenchymal stem cells.
Q34177504Study of expansion of porcine bone marrow mesenchymal stem cells on microcarriers using various operating conditions
Q54465514Supercharging allografts with mesenchymal stem cells in the operating room during hip revision.
Q53623785Supercharging irradiated allografts with mesenchymal stem cells improves acetabular bone grafting in revision arthroplasty.
Q35903711Surface Phosphatidylserine Is Responsible for the Internalization on Microvesicles Derived from Hypoxia-Induced Human Bone Marrow Mesenchymal Stem Cells into Human Endothelial Cells
Q36484494Surface tethered epidermal growth factor protects proliferating and differentiating multipotential stromal cells from FasL-induced apoptosis.
Q36736589Survival of hypoxic human mesenchymal stem cells is enhanced by a positive feedback loop involving miR-210 and hypoxia-inducible factor 1.
Q34934863Synthetic surface for expansion of human mesenchymal stem cells in xeno-free, chemically defined culture conditions
Q33722380Systemic Delivery of Bone Marrow Mesenchymal Stem Cells for In Situ Intervertebral Disc Regeneration
Q40733169TH17 predominant T-cell responses in radiation-induced bowel disease are modulated by treatment with adipose-derived mesenchymal stromal cells
Q34789088TNF receptor 2, not TNF receptor 1, enhances mesenchymal stem cell-mediated cardiac protection following acute ischemia.
Q52684314TSG-6 secreted by bone marrow mesenchymal stem cells attenuates intervertebral disc degeneration by inhibiting the TLR2/NF-κB signaling pathway.
Q92394719Targeting Purinergic Signaling and Cell Therapy in Cardiovascular and Neurodegenerative Diseases
Q46102792The Athena trials: Autologous adipose-derived regenerative cells for refractory chronic myocardial ischemia with left ventricular dysfunction.
Q41164454The Clinical Use of Human Culture-Expanded Autologous Bone Marrow Mesenchymal Stem Cells Transplanted on Platelet-Rich Fibrin Glue in the Treatment of Articular Cartilage Defects: A Pilot Study and Preliminary Results
Q41872607The Complex Ethics of First In Human Stem Cell Clinical Trials
Q41965784The Effect of Recombinant Human Interleukin-6 on Osteogenic Differentiation and YKL-40 Expression in Human, Bone Marrow-Derived Mesenchymal Stem Cells
Q58998678The Systems Biology of Stem Cell Released Molecules—Based Therapeutics
Q38175297The challenge of pancreatic cancer therapy and novel treatment strategy using engineered mesenchymal stem cells.
Q37531470The effect of a polyurethane-based reverse thermal gel on bone marrow stromal cell transplant survival and spinal cord repair
Q41033226The effect of autologous adipose derived mesenchymal stem cell therapy in the treatment of a large osteochondral defect of the knee following unsuccessful surgical intervention of osteochondritis dissecans - a case study.
Q36723735The effect of hypoxia on the chondrogenic differentiation of co-cultured articular chondrocytes and mesenchymal stem cells in scaffolds
Q38314723The enhanced effect of surface microstructured porous titanium on adhesion and osteoblastic differentiation of mesenchymal stem cells
Q36210791The fate of systemically administrated allogeneic mesenchymal stem cells in mouse femoral fracture healing
Q37792295The immunomodulatory properties of mesenchymal stem cells: implications for surgical disease.
Q38767642The influence of macrophages on mesenchymal stromal cell therapy: passive or aggressive agents?
Q36974665The pharmacology of regenerative medicine
Q37914769The possible roles of brain pericytes in brain ischemia and stroke
Q38340609The potential and challenges of using stem cells for cardiovascular repair and regeneration
Q38934189The potential impact of bone tissue engineering in the clinic
Q42069051The role of mouse mesenchymal stem cells in differentiation of naive T-cells into anti-inflammatory regulatory T-cell or proinflammatory helper T-cell 17 population
Q26997815The role of the myofibroblast in tumor stroma remodeling
Q90213463The role of ultrasound in enhancing mesenchymal stromal cell-based therapies
Q37807283The stem cell niche should be a key issue for cell therapy in regenerative medicine
Q37890316The therapeutic potential of bone marrow-derived stromal cells
Q89769517Therapeutic Mesenchymal Stromal Cells for Immunotherapy and for Gene and Drug Delivery
Q46235610Therapeutic effects of a combinatorial treatment of simvastatin and bone marrow stromal cells on experimental embolic stroke
Q48518649Therapeutic effects of intranigral transplantation of mesenchymal stem cells in rat models of Parkinson's disease
Q37900258Therapeutic factors secreted by mesenchymal stromal cells and tissue repair
Q34159047Therapeutic potential of adult bone marrow-derived mesenchymal stem cells in diseases of the skeleton
Q35726548Therapeutic potential of stem cells in orthopedics
Q37015790Tissue engineering strategies for promoting vascularized bone regeneration.
Q37791614Topical delivery of mesenchymal stem cells and their function in wounds
Q34576845Topically delivered adipose derived stem cells show an activated-fibroblast phenotype and enhance granulation tissue formation in skin wounds
Q34652682Total body irradiation is permissive for mesenchymal stem cell-mediated new bone formation following local transplantation.
Q33560685Toward brain tumor gene therapy using multipotent mesenchymal stromal cell vectors
Q38127722Toward the use of endometrial and menstrual blood mesenchymal stem cells for cell-based therapies.
Q36813588Tracking and Therapeutic Value of Human Adipose Tissue-derived Mesenchymal Stem Cell Transplantation in Reducing Venous Neointimal Hyperplasia Associated with Arteriovenous Fistula
Q35665292Tracking fusion of human mesenchymal stem cells after transplantation to the heart
Q91955604Tracking mesenchymal stem cells using magnetic resonance imaging
Q36529899Tracking of autologous adipose tissue-derived mesenchymal stromal cells with in vivo magnetic resonance imaging and histology after intralesional treatment of artificial equine tendon lesions--a pilot study
Q41698968Transplantation of Autologous Bone Marrow Mesenchymal Stem Cells with Platelet-Rich Plasma Accelerate Distraction Osteogenesis in A Canine Model.
Q51033029Transplantation of Cerebral Dopamine Neurotrophic Factor Transducted BMSCs in Contusion Spinal Cord Injury of Rats: Promotion of Nerve Regeneration by Alleviating Neuroinflammation.
Q50533414Transplantation of SNAP-treated adipose tissue-derived stem cells improves cardiac function and induces neovascularization after myocardium infarct in rats.
Q37681696Transplantation of hUC-MSCs seeded collagen scaffolds reduces scar formation and promotes functional recovery in canines with chronic spinal cord injury
Q54605762Transplantation of retrovirally transduced bone marrow prevents autoimmune disease in aged mice by peripheral tolerance mechanisms.
Q33856455Treatment of stress urinary incontinence with adipose tissue-derived stem cells
Q91719696Trends in mesenchymal stem cell clinical trials 2004-2018: Is efficacy optimal in a narrow dose range?
Q50269152Ultrastructural analysis of human bone marrow mesenchymal stem cells during in vitro osteogenesis and chondrogenesis
Q64950817Umbilical Cord-Derived Mesenchymal Stromal Cells (MSCs) for Knee Osteoarthritis: Repeated MSC Dosing Is Superior to a Single MSC Dose and to Hyaluronic Acid in a Controlled Randomized Phase I/II Trial.
Q48335025Unbiased and quantitative proteomics reveals highly increased angiogenesis induction by the secretome of mesenchymal stromal cells isolated from fetal rather than adult skin.
Q38766622Use of FGF-2 and FGF-18 to direct bone marrow stromal stem cells to chondrogenic and osteogenic lineages
Q38730790Use of genetically engineered stem cells for glioma therapy
Q41698188Variations of the micro-vascularization of the greater tuberosity in patients with rotator cuff tears
Q37456840Vascular endothelial growth factor (VEGF) as a key therapeutic trophic factor in bone marrow mesenchymal stem cell-mediated cardiac repair
Q36548884Viral-mediated fusion of mesenchymal stem cells with cells of the infarcted heart hinders healing via decreased vascularization and immune modulation
Q40394637Vulvar lichen sclerosus: A new regenerative approach through fat grafting.
Q84914069WITHDRAWN: Molecular Characteristics of Bone Marrow Mesenchymal Stem Cells: An Appealing Source for Regenerative Medicine
Q50997013[Mesenchymal stem cells and their interaction with biomaterials: potential applications in tissue engineering].
Q84742683[Mesenchymal stem cells for bone tissue engineering]
Q39805965p75 neurotrophin receptor is involved in proliferation of undifferentiated mouse embryonic stem cells.

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