Primary murine MSC show highly efficient homing to the bone marrow but lose homing ability following culture

scientific article published on 01 January 2003

Primary murine MSC show highly efficient homing to the bone marrow but lose homing ability following culture is …
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scholarly articleQ13442814

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P6179Dimensions Publication ID1008752494
P356DOI10.1038/SJ.LEU.2402763
P698PubMed publication ID12529674

P2093author name stringPloemacher RE
Rombouts WJ
P2860cites workCotransplantation of stroma results in enhancement of engraftment and early expression of donor hematopoietic stem cells in uteroQ73074029
Bone marrow-derived mesenchymal stem cells remain host-derived despite successful hematopoietic engraftment after allogeneic transplantation in patients with lysosomal and peroxisomal storage diseasesQ73180485
Repair of large bone defects with the use of autologous bone marrow stromal cellsQ73482003
Transplantation of gene-modified human bone marrow stromal cells into mouse-human bone chimerasQ73797744
Human mesenchymal stem cells support megakaryocyte and pro-platelet formation from CD34(+) hematopoietic progenitor cellsQ73821823
Ex vivo expansion of umbilical cord blood (UCB) CD34(+) cells alters the expression and function of alpha 4 beta 1 and alpha 5 beta 1 integrinsQ77231184
Homing efficiency, cell cycle kinetics, and survival of quiescent and cycling human CD34(+) cells transplanted into conditioned NOD/SCID recipientsQ77678262
Bone marrow cells regenerate infarcted myocardiumQ28210640
Use of mesenchymal stem cells in a collagen matrix for Achilles tendon repairQ28283228
Marrow stromal cells as stem cells for nonhematopoietic tissuesQ29618770
Mesenchymal stem cellsQ29619804
Cell surface antigens on human marrow-derived mesenchymal cells are detected by monoclonal antibodiesQ30195546
The monoclonal antibody SH-2, raised against human mesenchymal stem cells, recognizes an epitope on endoglin (CD105).Q30807148
The molecular basis for the cytokine-induced defect in homing and engraftment of hematopoietic stem cellsQ33183103
Transplantability and therapeutic effects of bone marrow-derived mesenchymal cells in children with osteogenesis imperfectaQ33855709
Role of mesenchymal stem cells in hematopoietic stem cell transplantationQ34072408
Cultured adherent cells from marrow can serve as long-lasting precursor cells for bone, cartilage, and lung in irradiated miceQ34269619
Ex vivo expansion and engraftment potential of cord blood-derived CD34+ cells in NOD/SCID mice.Q34310816
Rapid expansion of recycling stem cells in cultures of plastic-adherent cells from human bone marrowQ35107753
Marrow stromal cells as a source of progenitor cells for nonhematopoietic tissues in transgenic mice with a phenotype of osteogenesis imperfectaQ35796570
Engraftment and migration of human bone marrow stromal cells implanted in the brains of albino rats--similarities to astrocyte graftsQ36012180
Osteoblast-specific gene expression after transplantation of marrow cells: implications for skeletal gene therapyQ36394220
Cytogenetic studies on bone marrow fibroblasts from a male-female hematopoietic chimera. Evidence that stromal elements in human transplantation recipients are of host typeQ40853235
Green fluorescent protein variants as markers of retroviral-mediated gene transfer in primary hematopoietic cells and cell linesQ41109699
Recovery of hemopoietic stromal progenitor cells after lethal total-body irradiation and bone marrow transplantation in miceQ41966481
Donor origin of the in vitro haematopoietic microenvironment after marrow transplantation in man.Q42463848
The dynamic in vivo distribution of bone marrow-derived mesenchymal stem cells after infusion.Q43599448
Changes in integrin expression are associated with altered homing properties of Lin(-/lo)Thy1.1(lo)Sca-1(+)c-kit(+) hematopoietic stem cells following mobilization by cyclophosphamide/granulocyte colony-stimulating factorQ43873789
Human mesenchymal stem cells engraft and demonstrate site-specific differentiation after in utero transplantation in sheepQ45872229
Clinical responses to bone marrow transplantation in children with severe osteogenesis imperfectaQ45875073
Systemic delivery of human growth hormone or human factor IX in dogs by reintroduced genetically modified autologous bone marrow stromal cellsQ45880501
A quadripotential mesenchymal progenitor cell isolated from the marrow of an adult mouse.Q48215905
In vitro chondrogenesis of bone marrow-derived mesenchymal progenitor cells.Q50525701
Phenotypical and functional properties of human bone marrow mesenchymal progenitor cells.Q51088335
Host origin of marrow stromal cells following allogeneic bone marrow transplantationQ59068388
Recipient origin of bone marrow-derived fibroblastic stromal cells during all periods following bone marrow transplantation in humansQ67780726
Characterization of cells with osteogenic potential from human marrowQ68117980
An in vitro analysis of murine hemopoietic fibroblastoid progenitors and fibroblastoid cell function during agingQ70994307
Species differences in growth requirements for bone marrow stromal fibroblast colony formation In vitroQ71467805
Origin of human bone marrow fibroblastsQ72135391
Evaluation of mixed chimaerism and origin of bone marrow derived fibroblastoid cells after allogeneic bone marrow transplantationQ72490644
Transplantation of bone marrow fibroblastoid stromal cells in mice via the intravenous routeQ72552470
P433issue1
P304page(s)160-170
P577publication date2003-01-01
P1433published inLeukemiaQ6534498
P1476titlePrimary murine MSC show highly efficient homing to the bone marrow but lose homing ability following culture
P478volume17

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cites work (P2860)
Q365438467. Transplantation of undifferentiated, bone marrow-derived stem cells
Q61447325A case report on filamin A gene mutation and progressive pulmonary disease in an infant: A lung tissued derived mesenchymal stem cell study
Q41842342A comparative study of mesenchymal stem cell transplantation with its paracrine effect on control of hyperglycemia in type 1 diabetic rats.
Q27321219A small-molecule screen for enhanced homing of systemically infused cells
Q36648047A soluble granulocyte colony stimulating factor decoy receptor as a novel tool to increase hematopoietic cell homing and reconstitution in mice
Q28067094Activation, homing, and role of the mesenchymal stem cells in the inflammatory environment
Q28066235Adult Stem Cell Therapy for Stroke: Challenges and Progress
Q41261677Allogeneic Mesenchymal Stem Cell Therapy Promotes Osteoblastogenesis and Prevents Glucocorticoid-Induced Osteoporosis.
Q84195701Allogeneic mesenchymal stem cells do not protect NZBxNZW F1 mice from developing lupus disease
Q37126551Amniotic Fluid-Derived Mesenchymal Stem Cells Cut Short the Acuteness of Cisplatin-Induced Nephrotoxicity in Sprague-Dawley Rats
Q42554345Apoptotic endothelial cells demonstrate increased adhesiveness for human mesenchymal stem cells
Q41858303Are cultured mesenchymal stromal cells an option for immunomodulation in transplantation?
Q87840309Augmented migration of mesenchymal stem cells correlates with the subsidiary CXCR4 variant
Q28069791Biodistribution, migration and homing of systemically applied mesenchymal stem/stromal cells
Q35588431Bone marrow mesenchymal stem cells suppress metastatic tumor development in mouse by modulating immune system
Q89447778Bone marrow mesenchymal stem cells: Aging and tissue engineering applications to enhance bone healing
Q33820971Bright Polymer Dots Tracking Stem Cell Engraftment and Migration to Injured Mouse Liver
Q50650777CXCR5-Overexpressing Mesenchymal Stromal Cells Exhibit Enhanced Homing and Can Decrease Contact Hypersensitivity.
Q91825034Cancer-educated mesenchymal stem cells promote the survival of cancer cells at primary and distant metastatic sites via the expansion of bone marrow-derived-PMN-MDSCs
Q59793899Cell surface engineering and application in cell delivery to heart diseases
Q37716635Cell-autonomous heparanase modulates self-renewal and migration in bone marrow-derived mesenchymal stem cells
Q38809993Chemical and Physical Approaches to Extend the Replicative and Differentiation Potential of Stem Cells
Q35170330Chemistry and material science at the cell surface.
Q38122364Clinical applications of mesenchymal stem cells
Q37074199Comparative characterization of mesenchymal stem cells from eGFP transgenic and non-transgenic mice
Q37228699Comparative study of allogenic and xenogeneic mesenchymal stem cells on cisplatin-induced acute kidney injury in Sprague-Dawley rats
Q37419297Comparison of uncultured marrow mononuclear cells and culture-expanded mesenchymal stem cells in 3D collagen-chitosan microbeads for orthopedic tissue engineering
Q35188018Comparisons of mouse mesenchymal stem cells in primary adherent culture of compact bone fragments and whole bone marrow
Q41851257Comprehensive Screening of Cell Surface Markers Expressed by Adult-Derived Human Liver Stem/Progenitor Cells Harvested at Passage 5: Potential Implications for Engraftment.
Q58804653Concise Review: Mesenchymal Stem Cell-Based Drug Delivery: The Good, the Bad, the Ugly, and the Promise
Q47161681Concise Review: Quantitative Detection and Modeling the In Vivo Kinetics of Therapeutic Mesenchymal Stem/Stromal Cells.
Q35752045Conditions to improve expansion of human mesenchymal stem cells based on rat samples
Q92876658Copper promotes migration of adipose-derived stem cells by enhancing vimentin-Ser39 phosphorylation
Q35097806Corticosterone mediates the inhibitory effect of restraint stress on the migration of mesenchymal stem cell to carbon tetrachloride-induced fibrotic liver by downregulating CXCR4/7 expression
Q45869865Cotransplantation of third-party mesenchymal stromal cells can alleviate single-donor predominance and increase engraftment from double cord transplantation
Q35747904Culturing and characterization of human gingival mesenchymal stem cells and their chemotactic responses to stromal cell-derived factor-1
Q39647492Culturing of human mesenchymal stem cells as three-dimensional aggregates induces functional expression of CXCR4 that regulates adhesion to endothelial cells
Q58702140Current Strategies to Generate Human Mesenchymal Stem Cells In Vitro
Q48228534Deferoxamine promotes mesenchymal stem cell homing in noise-induced injured cochlea through PI3K/AKT pathway.
Q34751252Deficiency of lipid phosphatase SHIP enables long-term reconstitution of hematopoietic inductive bone marrow microenvironment
Q36591615Density-Dependent Metabolic Heterogeneity in Human Mesenchymal Stem Cells
Q34206151Differential mechanical response of mesenchymal stem cells and fibroblasts to tumor-secreted soluble factors
Q40727194Discrepancy between the in vitro and in vivo effects of murine mesenchymal stem cells on T-cell proliferation and collagen-induced arthritis
Q37459109Diversity of ion channels in human bone marrow mesenchymal stem cells from amyotrophic lateral sclerosis patients
Q46332910Do adipose tissue-derived mesenchymal stem cells ameliorate Parkinson's disease in rat model?
Q33286093Dynamics of adipogenic promoter DNA methylation during clonal culture of human adipose stem cells to senescence
Q28579033Effect of in vitro passaging on the stem cell-related properties of tendon-derived stem cells-implications in tissue engineering
Q26740408Effects of Oxidative Stress on Mesenchymal Stem Cell Biology
Q35623682Engineered cell homing
Q40734038Engineered mesenchymal stem cells with self-assembled vesicles for systemic cell targeting
Q27026414Engineering mesenchymal stem cells for regenerative medicine and drug delivery
Q92801341Enhancement of Mesenchymal Stem Cell-Driven Bone Regeneration by Resveratrol-Mediated SOX2 Regulation
Q55271061Enhancement of Replication and Differentiation Potential of Human Bone Marrow Stem Cells by Nicotinamide Treatment.
Q42057790Enhancing the migration ability of mesenchymal stromal cells by targeting the SDF-1/CXCR4 axis
Q64931629FGF2 Induces Migration of Human Bone Marrow Stromal Cells by Increasing Core Fucosylations on N-Glycans of Integrins.
Q34591315Fate of bone marrow-derived stromal cells after intraperitoneal infusion or implantation into femoral bone defects in the host animal
Q36257063From bench to bedside: use of human adipose-derived stem cells.
Q40080450Gene Delivery Approaches for Mesenchymal Stem Cell Therapy: Strategies to Increase Efficiency and Specificity
Q92573477Generation of mesenchymal stem-like cells for producing extracellular vesicles
Q52694972Genetic modification to induce CXCR2 overexpression in mesenchymal stem cells enhances treatment benefits in radiation-induced oral mucositis.
Q92017633Genetically modified mesenchymal stem cell therapy for acute respiratory distress syndrome
Q36195612Genome-scale DNA methylation pattern profiling of human bone marrow mesenchymal stem cells in long-term culture
Q28251644Glycosyltransferase-programmed stereosubstitution (GPS) to create HCELL: engineering a roadmap for cell migration
Q46491134Haematopoietic lineage-committed bone marrow cells, but not cloned cultured mesenchymal stem cells, contribute to regeneration of renal tubular epithelium after HgCl 2 -induced acute tubular injury
Q35589763Hematopoietic bone marrow cells participate in endothelial, but not epithelial or mesenchymal cell renewal in adult rats
Q36840751Hepatocyte growth factor/Met gene transfer in cardiac stem cells--potential for cardiac repair
Q41117689High glucose microenvironments inhibit the proliferation and migration of bone mesenchymal stem cells by activating GSK3β.
Q48949711High-resolution imaging of bone precursor cells within the intact bone marrow cavity of living mice.
Q37788681Homing Pathways of Mesenchymal Stromal Cells (MSCs) and Their Role in Clinical Applications
Q26750318Homing and migration of mesenchymal stromal cells: How to improve the efficacy of cell therapy?
Q41900937Human ESC-derived MSCs outperform bone marrow MSCs in the treatment of an EAE model of multiple sclerosis
Q36340132Human embryonic stem cell-derived mesenchymal cells preserve kidney function and extend lifespan in NZB/W F1 mouse model of lupus nephritis
Q38806320Human umbilical cord mesenchymal stem cells delivering sTRAIL home to lung cancer mediated by MCP-1/CCR2 axis and exhibit antitumor effects
Q38118664Identification of perivascular mesenchymal stromal/stem cells by flow cytometry.
Q27004487Immunobiology of mesenchymal stem cells
Q43413726Importance of Sox2 in maintenance of cell proliferation and multipotency of mesenchymal stem cells in low-density culture.
Q40023771Improved lentiviral transduction of human mesenchymal stem cells for therapeutic intervention in pancreatic cancer
Q40279933In vitro effect of adenovirus-mediated human Gamma Interferon gene transfer into human mesenchymal stem cells for chronic myelogenous leukemia
Q42651171In vivo distribution of human adipose-derived mesenchymal stem cells in novel xenotransplantation models
Q24812198Influence of hypoxia on the domiciliation of mesenchymal stem cells after infusion into rats: possibilities of targeting pulmonary artery remodeling via cells therapies?
Q36106898Intra-Bone Marrow Transplantation of Endosteal Bone Marrow Cells Facilitates Allogeneic Hematopoietic and Stromal Cells Engraftment Dependent on Early Expression of CXCL-12.
Q39247025Intramarrow injection of beta-catenin-activated, but not naive mesenchymal stromal cells stimulates self-renewal of hematopoietic stem cells in bone marrow
Q42291750In Vitro Generation of Vascular Wall-Resident Multipotent Stem Cells of Mesenchymal Nature from Murine Induced Pluripotent Stem Cells
Q30480238Isolation of a mesenchymal cell population from murine dermis that contains progenitors of multiple cell lineages
Q50500441Isolation of mouse mesenchymal stem cells on the basis of expression of Sca-1 and PDGFR-α.
Q36055845Journey of mesenchymal stem cells for homing: strategies to enhance efficacy and safety of stem cell therapy
Q41788181LNGFR(+)THY-1(+)VCAM-1(hi+) cells reveal functionally distinct subpopulations in mesenchymal stem cells
Q34634748Local delivery of mesenchymal stem cells with poly-lactic-co-glycolic acid nano-fiber scaffold suppress arthritis in rats
Q42039222Long Term Study of Protective Mechanisms of Human Adipose Derived Mesenchymal Stem Cells on Cisplatin Induced Kidney injury in Sprague-Dawley Rats
Q39366416Long-term engraftment and angiogenic properties of lentivirally transduced adipose tissue-derived stromal cells
Q33877074Long-term self-renewal of postnatal muscle-derived stem cells
Q38784475Magnetic Nanoparticle Based Nonviral MicroRNA Delivery into Freshly Isolated CD105(+) hMSCs
Q46307085Mammalian MSC from selected species: Features and applications
Q92830126Manufacturing of primed mesenchymal stromal cells for therapy
Q36705331Mechanical signals promote osteogenic fate through a primary cilia-mediated mechanism
Q37223035Mesenchymal Stem Cells Derived from Human Exocrine Pancreas Spontaneously Express Pancreas Progenitor-Cell Markers in a Cell-Passage-Dependent Manner
Q64060139Mesenchymal Stem Cells: Characteristics, Function, and Application
Q64274626Mesenchymal Stromal Cell Homing: Mechanisms and Strategies for Improvement
Q30009860Mesenchymal stem cell and regenerative medicine: regeneration versus immunomodulatory challenges
Q33861809Mesenchymal stem cell population derived from human pluripotent stem cells displays potent immunomodulatory and therapeutic properties
Q33898653Mesenchymal stem cell therapy: Two steps forward, one step back
Q35889077Mesenchymal stem cell-based therapy: a new paradigm in regenerative medicine
Q26827457Mesenchymal stem cells as a therapeutic approach to glomerular diseases: benefits and risks
Q26853498Mesenchymal stem cells as vectors for lung cancer therapy
Q37236694Mesenchymal stem cells as vectors for lung disease
Q33886115Mesenchymal stem cells can participate in ischemic neovascularization
Q26801575Mesenchymal stem cells for the treatment of neurodegenerative and psychiatric disorders
Q52584250Mesenchymal stem cells homing to improve bone healing.
Q27003059Mesenchymal stem cells migration homing and tracking
Q89866297Mesenchymal stem cells suppress leukemia via macrophage-mediated functional restoration of bone marrow microenvironment
Q35921652Mesenchymal stem/stromal cells-a key mediator for regeneration after perinatal morbidity?
Q38499617Mesenchymal stromal cells to halt the progression of type 1 diabetes?
Q90258158Migration of mesenchymal stem cells to tumor xenograft models and in vitro drug delivery by doxorubicin
Q30503541Mimicking the inflammatory cell adhesion cascade by nucleic acid aptamer programmed cell-cell interactions.
Q34060825Modulation of stromal cell-derived factor-1/CXC chemokine receptor 4 axis enhances rhBMP-2-induced ectopic bone formation
Q37687143Molecular mechanisms involved in mesenchymal stem cell migration to the site of acute myocardial infarction
Q37962744Molecular mediators of mesenchymal stem cell biology
Q79149791Nonexpanded primary lung and bone marrow–derived mesenchymal cells promote the engraftment of umbilical cord blood–derived CD34+ cells in NOD/SCID mice
Q36195006Notch2 Signaling Regulates the Proliferation of Murine Bone Marrow-Derived Mesenchymal Stem/Stromal Cells via c-Myc Expression
Q58713633Novel preconditioning strategies for enhancing the migratory ability of mesenchymal stem cells in acute kidney injury
Q39761993Nuclear receptors Nur77 and Nurr1 modulate mesenchymal stromal cell migration
Q37034680Perspectives on the use of mesenchymal stem cells in vascularized composite allotransplantation
Q39203644Potential of bone marrow mesenchymal stem cells in management of Alzheimer's disease in female rats
Q34367266Potential of mesenchymal stem cells in gene therapy approaches for inherited and acquired diseases
Q42252561Primary mesenchymal stem and progenitor cells from bone marrow lack expression of CD44 protein
Q64249676Production of Mesenchymal Stem Cells Through Stem Cell Reprogramming
Q89128870Programming Cell-Cell Interactions through Non-genetic Membrane Engineering
Q42594348Prospective identification, isolation, and systemic transplantation of multipotent mesenchymal stem cells in murine bone marrow.
Q35036107Quantification of Mesenchymal Stem Cell (MSC) delivery to a target site using in vivo confocal microscopy
Q33796581Radiation rescue: mesenchymal stromal cells protect from lethal irradiation
Q49343380Reduced neuroprotective potential of the mesenchymal stromal cell secretome with ex vivo expansion, age and progressive multiple sclerosis
Q36185562Regenerative effects of transplanted mesenchymal stem cells in fracture healing
Q37890947Regulatory factors of mesenchymal stem cell migration into injured tissues and their signal transduction mechanisms
Q26825380Role of mesenchymal stem cells in bone regeneration and fracture repair: a review
Q39780663Role of mesenchymal stem cells versus angiotensin converting enzyme inhibitor in kidney repair
Q37311003Secretion of SDF-1alpha by bone marrow-derived stromal cells enhances skin wound healing of C57BL/6 mice exposed to ionizing radiation
Q26742060Senescence in Human Mesenchymal Stem Cells: Functional Changes and Implications in Stem Cell-Based Therapy
Q38232804Senescence suppressors: their practical importance in replicative lifespan extension in stem cells
Q55665217Serum-mediated Activation of Bone Marrow-derived Mesenchymal Stem Cells in Ischemic Stroke Patients: A Novel Preconditioning Method.
Q36797479Simvastatin improves the homing of BMSCs via the PI3K/AKT/miR-9 pathway
Q92701228Spontaneously Formed Spheroids from Mouse Compact Bone-Derived Cells Retain Highly Potent Stem Cells with Enhanced Differentiation Capability
Q34348053Stem cell homing in musculoskeletal injury
Q37730300Stem cells as vectors for antitumour therapy
Q91905837Strategies to enhance efficacy of SPION-labeled stem cell homing by magnetic attraction: a systemic review with meta-analysis
Q37126556Study of the Effect of Route of Administration of Mesenchymal Stem Cells on Cisplatin-Induced Acute Kidney Injury in Sprague Dawley Rats
Q80641442Targeted migration of mesenchymal stem cells modified with CXCR4 gene to infarcted myocardium improves cardiac performance
Q37879593Tendon-derived stem cells (TDSCs): from basic science to potential roles in tendon pathology and tissue engineering applications.
Q92996936The Analysis of In Vivo Aging in Human Bone Marrow Mesenchymal Stromal Cells Using Colony-Forming Unit-Fibroblast Assay and the CD45lowCD271+ Phenotype
Q59797883The Dynamic Roles of Mesenchymal Stem Cells in Colon Cancer
Q90747233The Effect of Smoking Behavior on Alveolar Bone Marrow Mesenchymal Stem Cells of Clinical Implant Patient
Q90279588The Pros and Cons of Mesenchymal Stem Cell-Based Therapies
Q38218112The life and fate of mesenchymal stem cells
Q57789098The optimal time to inject bone mesenchymal stem cells for fracture healing in a murine model
Q37857736The origins of mesenchymal stromal cell heterogeneity
Q34961830The potential role of stem cells in the treatment of urinary incontinence
Q37894571The role of chemokines in mesenchymal stem cell homing to myocardium
Q49575147Therapeutic Benefit for Late, but Not Early, Passage Mesenchymal Stem Cells on Pain Behaviour in an Animal Model of Osteoarthritis.
Q59807954Therapeutic Effect of Human Umbilical Cord Mesenchymal Stem Cells at Various Passages on Acute Liver Failure in Rats
Q89737509Therapeutic Potential of Wharton's Jelly Mesenchymal Stem Cells for Diabetes: Achievements and Challenges
Q49546556Therapeutic utilization of stem cells in orthopedics
Q38181868Use of genetically modified mesenchymal stem cells to treat neurodegenerative diseases
Q64070333Xenogeneic Transplantation of Human Placenta-Derived Mesenchymal Stem Cells Alleviates Renal Injury and Reduces Inflammation in a Mouse Model of Lupus Nephritis
Q83514683[Mesenchymal stromal cells: Biological properties and clinical prospects]
Q30548207mRNA-engineered mesenchymal stem cells for targeted delivery of interleukin-10 to sites of inflammation.

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