Inhibition of hepatocellular carcinoma growth by adenovirus-mediated expression of human telomerase reverse transcriptase COOH-27 terminal polypeptide in mice

scientific article published on 16 July 2013

Inhibition of hepatocellular carcinoma growth by adenovirus-mediated expression of human telomerase reverse transcriptase COOH-27 terminal polypeptide in mice is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.3892/OL.2013.1470
P932PMC publication ID3789117
P698PubMed publication ID24137404
P5875ResearchGate publication ID258056483

P2093author name stringYi Li
Hsiang-Fu Kung
Yi-Dong Wang
Ying Peng
Lei He
Dan Xie
Jun-Jian Huang
Xiang-Pen Li
Han-Xian Gong
P2860cites workSpecific Association of Human Telomerase Activity with Immortal Cells and CancerQ27860801
Use of transcriptional regulatory sequences of telomerase (hTER and hTERT) for selective killing of cancer cellsQ28140743
The hTERT promoter enhances the antitumor activity of an oncolytic adenovirus under a hypoxic microenvironmentQ28728396
Interleukin-2 and inflammation induce distinct transcriptional programs that promote the differentiation of effector cytolytic T cellsQ34003618
Telomerase and cancerQ34188981
Tumor antigen-specific T helper cells in cancer immunity and immunotherapyQ34433202
Intravascular adenoviral agents in cancer patients: lessons from clinical trialsQ35043094
Management of patients with hepatitis B virus-induced cirrhosisQ36074827
Cancer immunotherapy targeting the telomerase reverse transcriptase.Q36426098
A rapid method for accurate DNA measurements in single cells in situ using a simple microfluorimeter and Hoechst 33258 as a quantitative fluorochromeQ36588957
Effective antitumor immunity against murine gliomas using dendritic cells transduced with hTERTC27 recombinant adenovirusQ36642484
Current treatment strategy for hepatocellular carcinoma.Q36927996
Mesenchymal stem cells expressing TRAIL lead to tumour growth inhibition in an experimental lung cancer modelQ37310677
Diepitope multiple antigen peptide of hTERT trigger stronger anti-tumor immune responses in vitroQ39146626
Interleukin-2 gene transfer potentiates the alpha-galactosylceramide-stimulated antitumor effect by the induction of TRAIL in NKT and NK cells in mouse models of subcutaneous and metastatic carcinomaQ39776994
In vitro generation of cytotoxic and regulatory T cells by fusions of human dendritic cells and hepatocellular carcinoma cellsQ39939752
A novel glioblastoma cancer gene therapy using AAV-mediated long-term expression of human TERT C-terminal polypeptide.Q40154353
Cytotoxic T cell responses to human telomerase reverse transcriptase in patients with hepatocellular carcinomaQ40275006
Gene therapy for renal anemia in mice with polycystic kidney using an adenovirus vector encoding the human erythropoietin geneQ40961003
Current management strategy of hepatocellular carcinomaQ43093342
Development of recombinant adeno-associated virus and adenovirus cocktail system for efficient hTERTC27 polypeptide-mediated cancer gene therapyQ43648101
Hepatic arterial infusion of a replication-selective oncolytic adenovirus (dl1520): phase II viral, immunologic, and clinical endpointsQ44203789
Induction of anti-tumour immunity by dendritic cells transduced with hTERT recombinant adenovirus in miceQ44260085
Dendritic cells transduced with recombinant adenoviruses induce more efficient anti-tumor immunity than dendritic cells pulsed with peptideQ44735356
Type 2 cytotoxic T lymphocytes modulate the activity of dendritic cells toward type 2 immune responses.Q45861552
Morphine promotes Jurkat cell apoptosis through pro-apoptotic FADD/P53 and anti-apoptotic PI3K/Akt/NF-kappaB pathwaysQ46985164
Expression of liver phenotypes in cultured mouse hepatoma cellsQ53532544
Phase II clinical trial of intralesional administration of the oncolytic adenovirus ONYX-015 in patients with hepatobiliary tumors with correlative p53 studiesQ64378032
A novel oncolytic adenovirus targeting to telomerase activity in tumor cells with potentQ64379609
Ectopic expression of a COOH-terminal fragment of the human telomerase reverse transcriptase leads to telomere dysfunction and reduction of growth and tumorigenicity in HeLa cellsQ74198983
Survival benefit of transcatheter arterial chemoembolization in patients with hepatocellular carcinoma larger than 10 cm in diameterQ82173274
P433issue3
P921main subjectAdenoviridaeQ193447
hepatocellular carcinomaQ1148337
P304page(s)748-752
P577publication date2013-07-16
P1433published inOncology LettersQ20640514
P1476titleInhibition of hepatocellular carcinoma growth by adenovirus-mediated expression of human telomerase reverse transcriptase COOH-27 terminal polypeptide in mice
P478volume6

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cites work (P2860)
Q39358916Cellular and molecular targets for the immunotherapy of hepatocellular carcinoma
Q41577558Long-term toxicity study of rAd5-hTERTC27 in SD rats and Cynomolgus monkeys by intravenous injection
Q42285876Preclinical safety evaluation of rAd5-hTERTC27 by intravenous injection

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